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Journal : Health Notions

Green Tea (EGCG) Decreases Malondialdehide in Oxidative Stress Exposure to Psychological Stress M. Dodi F Priaminda; Bambang Wirjatmadi; Bambang Purwanto; Merryana Adriani
Health Notions Vol 2, No 7 (2018): July
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn20707

Abstract

Exposure to psychological stress can cause oxidative stress. Provision of exogenous antioxidants is expected to reduce the occurrence of oxidative stress. Green tea with its active ingredient Epigalocatechin Galat is considered to reduce the occurrence of oxidative stress. The purpose of this study was to examine the administration of green tea (EGCG) on the effect decreasing MDA levels against Wistar Strain (Rattus norvegicus) white rats exposed to psychological stress; with Randomized Post Test design of only group design by grouping into 5 groups, with control group and treatment group. Administration of steeping green tea (EGCG) with a single dose. To find out the significant influence of the independent variable on a set of variable group tested Manova. Post hoc testing using LSD (Least Significance Different) was performed to see significant differences between groups. In this study, obtained MDA data with significant decrease at the 6th hours after consum EGCG. Keywords: oxidative stress; green tea, EGCG, malondialdehide
Robusta Coffee Decreased Malondialdehyde Levels in Wistar Mice Experiencing Oxidative Stress Rahmi Syarifatun Abidah; Bambang Wirjatmadi; Bambang Purwanto; Merryana Adriani
Health Notions Vol 1, No 4 (2017): October-December
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (607.78 KB) | DOI: 10.33846/hn.v1i4.68

Abstract

Coffee drinking is a habit that still doubtful for it’s benefits. Many active ingredients in robusta coffee (Coffea canephora) are very useful for health, especially the antioxidant content that can ward off free radicals that absorbed in the body. Free radicals can be caused by psychological stress exposure. Excessive amounts of radicals in the body cause oxidative stress. This study aimed to see the robusta coffee effect on decreasing levels of Malondialdehyde (MDA) with “randomized post test only control group” design with 25 samples of white male rat strain wistar (Rattus norvegicus). Samples were divided into 5 groups: control groups and randomized treatment groups. Treatment given in psychological stress and giving robusta coffee drink with single dose. This study used “one way anova” test and followed by “pos hoc tukey HSD” test for statistics. Robusta coffee had an effect in MDA levels changing. There was a MDA levels decreasing in 1 hour after robusta coffee drinking in experimental rats with oxidative stress conditions that were exposed by psychological stress. Keywords: Robusta coffee, Malondialdehyde, Oxidative stress
Cocoa liquor increases SOD activity in wistar rats experiencing oxidative stress Kartika Wahyu Dwi Putra; Bambang Wirjatmadi; Bambang Purwanto; Merryana Adriani
Health Notions Vol 2, No 1 (2018): January
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.472 KB) | DOI: 10.33846/hn.v2i1.98

Abstract

Chocolate is a healthy food. The active ingredient in chocolate (Theobroma cacao L.), especially antioxidants, can counteract the free radicals present in the body. This study aimed to determine the effect of cocoa liquor on increased activity of Superoxyde Dismutase (SOD). The study design was randomized post test only control group with 20 samples of male white rats wistar (Rattus norvegicus). The sample was divided into 4 groups: 2 control groups and 2 treatment groups. The treatments provided were instantaneous physical activity and cocoa liquor preparation with a single dose. This study used one way anova and continued with post hoc tukey HSD test for statistic. The results showed that cocoa liquor had an effect on SOD activity. SOD activity increased in treatment group with cocoa liquor either 2 hours or 24 hours before the momentary physical activity. Keywords: Cocoa liquor, Superoxide dismutase, Oxidative stress
Intake of Folic Acid During Pregnancy Correlates to Preeclampsia Incidents in Health Center of Surabaya Putri Ulin Nuha; Bambang Purwanto; Rizki Pranadyan; Dwi Purwanti
Health Notions Vol 2, No 5 (2018): May
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.061 KB) | DOI: 10.33846/hn.v2i5.195

Abstract

Maternal Mortality Rate (MMR) in Indonesia based on 2015’s Health Profile of Indonesia has reached 305 per 100,000 live births. Preeclampsia is known being one of the most related factors of MMR Studies suggest that the use of folic acid may lower the risk of hypertensive disorders in pregnancy. It has been suggested that folic acid and Folic acid containing multivitamins may reduce the risk of preeclampsia by lowering plasma homocysteine concentrations in pregnant women. This cross sectional study aimed to analyze the correlation between intake of Folic acid with preeclampsia. Data was taken using Food Frequency Questionaire (FFQ) with semi quantitative approach by interviewing subjects. Sampling was obtained by simple random sampling with total 80 subjects. Data was analyzed using Chi square test. There were 15% of subjects diagnosed with preeclampsia and 83.3% of women with preeclampsia were deficient of Folic acid. Data analysis showed there is correlation between intake of Folic acid during pregnancy with preeclampsia in Sidotopo Wetan Health Care Centre (p= 0.028), while OR value was 0.158 (95% CI 0.032 to 0.776). It can be concluded that insufficient intake of Folic acid during pregnancy correlate to preeclampsia incidents. Keywords: Folic Acid, Preeclampsia, Incidents, Pregnancy
Both Acute and Chronic Exercise Decrease Total Cholesterol Level in Human Blood Bambang Purwanto; Wahyu N. Pratiwi; Abdurachman Abdurachman
Health Notions Vol 2, No 9 (2018): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (107.872 KB) | DOI: 10.33846/hn.v2i9.319

Abstract

Exercise such as Diabetes dance of Persadia 1 is the evolvement of prior diabetes dance series with aerobic principle with more eccentric movement. Diabetes dance of Persadia 1 has been inspected effective for lowering fasting blood glucose, but its still unknown about its effect on blood level of total cholesterol. The aim of this research was to analyze the effect of exercise on total cholesterol level. This research was experimental study, with 16 subject of healthy housewifes and divided on 2 groups, that were exercise and control group. Exercise group was given with diabetes dance of Persadia 1 while control group have the unstructured activity. Blood level of total cholesterol (TC) has been measured after 24 hours post single bout exercise (acute-AE) and repeated exercise (chronic exercise-CE). Paired t-test analysis on both acute (AC) (p=0.005) and chronic (CC) (p=0.006) shows TC decrease significantly on control group, as well as on AE (p=0.001) and CE (p=0.001). However, TC tend to increase on CC though not significantly increase (p=0.916), while on CE tend to decrease significantly (p=0.041). This study showed that both acute and cronic exercise decrease total cholesterol level in human blood. Keywords: Interleukin-6, Total cholesterol level, Exercise