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EFEK EKSTRAK ETANOLIK DAUN BAYAM MERAH (Amaranthus tricolor L.) TERSTANDAR TERHADAP INDEKS MASSA TUBUH DAN KADAR GLUKOSA DARAH PADA TIKUS SPRAGUE DAWLEY YANG DIBERIKAN DIET TINGGI LEMAK SEBAGAI UPAYA PREVENTIF OBESITAS Cynthia Astiti Putri; Dimas Adhi Pradana; Qrio Susanto
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 13 No. 02 Desember 2016
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v13i02.1251

Obesitas terbukti menyebabkan peningkatan resiko morbiditas dan mortalitas dari beberapa penyakit seperti diabetes melitus tipe-2. Terdapat korelasi positif antara kejadian obesitas dan peningkatan kadar glukosa darah. Bayam merah (Amaranthus tricolor L.) merupakan tanaman obat yang diketahui memiliki aktivitas preventif terjadinya obesitas. Salah satu upaya peningkatan kualitas obat herbal dapat dilakukan dengan pembuatan ekstrak herbal terstandar. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanolik daun bayam merah terstandar sebagai preventif obesitas berdasarkan parameter indeks massa tubuh dan kadar glukosa darah pada tikus galur Sprague Dawley jantan yang diinduksi diet tinggi lemak. Tiga puluh hewan uji dibagi 6 kelompok, yaitu kelompok kontrol normal, kontrol negatif, kontrol positif (Orlistat 10,8 mg/kg bb), dosis I (200 mg/kg bb), dosis II (400 mg/kg bb), dan dosis III (800 mg/kg bb). Ekstrak etanolik daun bayam merah secara oral diberikan hari ke-1 sampai hari ke-67, dilanjutkan induksi diet tinggi lemak hari ke-8 sampai hari ke-67 dua jam setelah pemberian terapi. Berdasarkan hasil uji aktivitas ekstrak etanolik daun bayam merah, dosis 200 dan 400 mg/kg bb memiliki aktivitas sebagai preventif obesitas berdasarkan parameter indeks massa tubuh dan kadar glukosa darah (p

Pemberdayaan Kader dalam Pembentukan Pos Pembinaan Terpadu (Posbindu) Penyakit Tidak Menular di Ngandong Sleman Yogyakarta: Empowerment of Cadres in the Establishment of Posbindu Non-Communicable Diseases in Ngandong Sleman Yogyakarta Erlina Marfianti; Sunarto Sunarto; Dimas Adhi Pradana
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 7 No. 4 (2022): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v7i4.2928

The prevalence of non-communicable diseases (NCD) in Indonesia is currently increasing. Data from WHO states that 71% of the causes of death worldwide are NCD. Control of risk factors and early detection of non-communicable diseases (NCD) are the keys to reducing the number of cases and mortality of NCD. Posbindu is a preventive, promotive effort that involves community participation. The ability of cadres and community awareness are not the same in every area. In this regard, our community service activities aim to optimize cadres in controlling NCD through the establishment and implementation of Posbindu. This program consists of 5 actions: Training of cadres about Posbindu, Counseling, and education to cadres and the community about non-communicable diseases, especially hypertension and diabetes mellitus, Procurement and training on the use of medical devices for Posbindu, Creation of information and communication media for health education to the public, and Establishment of Posbindu and its implementation. The results of this program are increasing the understanding of cadres about Posbindu, increasing the knowledge of cadres and the community about NCD, and the formation of Posbindu, which has been implemented in the community. Active participation of the cadres and the community is expected to ensure the continuity of this activity.

Hyperlipidemia Preventing Activities of Standardized Ethanolic Extract of Red Spinach (Amaranthus tricolor L.): An In Vivo Study in Male Sprague-Dawley Rats Pradana, Dimas Adhi; Apriani, Lalily; Widyarini, Sitarina
Jurnal Kefarmasian Indonesia VOLUME 8, NOMOR 2, AGUSTUS 2018
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v8i2.349

Lipid metabolism disorders can lead to hyperlipidemia that triggers atherosclerosis. This study aimed to identify the potential of standardized ethanolic extract of red spinach (Amaranthus tricolor L.) to prevent hyperlipidemia by referring to the reduction of triglyceride level and total cholesterols in male Sprague-Dawley rats. A total of 30 experimental animals was put into 6 groups, including normal, positive control (0.9 mg/kgBW of simvastatin), negative control, treatment I (200 mg/kgBW of extract), treatment II (400 mg/kgBW of extract), and treatment III (800 mg/kgBW of extract). Preventive therapy and positive control were administered from day 1 to day 67. Hyperlipidemia was induced by feeding pure lard and duck yolk to the rats twice daily from day 8 to day 67. Determination of triglyceride level and total cholesterols was conducted on day 0 and day 67. The findings revealed that the treatment groups with ethanolic extract of red spinach at doses of 200 mg/kgBW, 400 mg/kgBW, and 800 mg/kgBW had statistically significant differences (p

Peningkatan Pengetahuan dan Sikap Masyarakat Tentang Tuberculosis dengan Leaflet di RT 04 Ngemplak Kembang Arum Winano, Agus; Handayani, Erny Tri; Ayuningrum, Fahmay Dwi; P, Leonardus Rayvaldo K.; Bili, Losarida Amelia; Amar, Muhammad; Suwerda, Bambang; Pradana, Dimas Adhi
JGEN : Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 2 (2024): JGEN : Jurnal Pengabdian Kepada Masyarakat, Desember 2024
Publisher : Lumbung Pare Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60126/jgen.v2i2.501

Tuberkulosis (TBC) masih menjadi ancaman kesehatan global, dengan Indonesia menduduki peringkat kedua jumlah pengidap TBC terbanyak di dunia. Penelitian ini bertujuan untuk mengetahui pengaruh promosi kesehatan menggunakan media leaflet terhadap tingkat pengetahuan dan sikap masyarakat dalam pencegahan TBC. Metode yang digunakan adalah pre-eksperimen dengan desain one group pre-test post-test. Responden penelitian adalah 30 ibu rumah tangga di RT 04 Dukuh Ngemplak Kembang Arum, Kecamatan Turi, Kabupaten Sleman, Yogyakarta. Data dikumpulkan melalui kuesioner sebelum dan sesudah penyuluhan. Hasil penelitian menunjukkan adanya peningkatan signifikan pada pengetahuan dan sikap responden setelah diberikan penyuluhan (p<0,05). Tingkat pengetahuan tinggi meningkat dari 63% menjadi 100%, sedangkan sikap baik meningkat dari 83% menjadi 100%. Kesimpulannya, promosi kesehatan menggunakan media leaflet efektif dalam meningkatkan pengetahuan dan sikap masyarakat terhadap pencegahan TBC. Disarankan untuk melakukan penyuluhan secara berkala dan mengoptimalkan penggunaan media edukasi lainnya untuk meningkatkan efektivitas pencegahan TBC di masyarakat.

Design of a Web-Based Pain Module for a Medication Record Application to Support Pharmacist Self-Medication Services: Design of a Web-Based Pain Module for a Medication Record Application to Support Pharmacist Self-Medication Services Suraya Baharun; Dimas Adhi Pradana; Sri Haryanti
Media Farmasi Indonesia Vol. 20 No. 2 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i2.326

Today's pharmacists' roles in healthcare services are changing quickly, and the key to staying up to date is internet-based drug records. Pharmacists have a significant impact on the field of health technology, particularly when it comes to patient medication records through the use of certain technologies. As professionals, pharmacists must play a bigger part in using digital technology to help improve patient safety and public health (patient safety). Medication records are one of the documents from pharmaceutical services carried out by pharmacists in pharmacies. Web-based pharmacist medication records can be used to document the provision of over-the-counter medications, referred to as self-medication services. This study aims to determine the usability of the web-based pharmacist medication record application developed as a supporting tool for community pharmacists in self-medication services. The research method used is Research and Development (R&D). The initial stage of the research involved interviews with 10 pharmacists to identify the needs of the application. Based on the interview results, self-medication for pain is the most common case occurring in pharmacies, so the researchers added a pain module to this application. Usability testing was conducted using the USE questionnaire to 135 respondents (45 pharmacists and 90 patients) in the city of Semarang. The test results show that the application meets usability criteria with the categories of usefulness, easy of use, easy learning, and satisfaction.

EFEK EKSTRAK ETANOLIK DAUN BAYAM MERAH (Amaranthus tricolor L.) TERSTANDAR TERHADAP INDEKS MASSA TUBUH DAN KADAR GLUKOSA DARAH PADA TIKUS SPRAGUE DAWLEY YANG DIBERIKAN DIET TINGGI LEMAK SEBAGAI UPAYA PREVENTIF OBESITAS Cynthia Astiti Putri; Dimas Adhi Pradana; Qrio Susanto
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), Vol. 13 No. 02 Desember 20
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v13i02.1251

Obesitas terbukti menyebabkan peningkatan resiko morbiditas dan mortalitas dari beberapa penyakit seperti diabetes melitus tipe-2. Terdapat korelasi positif antara kejadian obesitas dan peningkatan kadar glukosa darah. Bayam merah (Amaranthus tricolor L.) merupakan tanaman obat yang diketahui memiliki aktivitas preventif terjadinya obesitas. Salah satu upaya peningkatan kualitas obat herbal dapat dilakukan dengan pembuatan ekstrak herbal terstandar. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanolik daun bayam merah terstandar sebagai preventif obesitas berdasarkan parameter indeks massa tubuh dan kadar glukosa darah pada tikus galur Sprague Dawley jantan yang diinduksi diet tinggi lemak. Tiga puluh hewan uji dibagi 6 kelompok, yaitu kelompok kontrol normal, kontrol negatif, kontrol positif (Orlistat 10,8 mg/kg bb), dosis I (200 mg/kg bb), dosis II (400 mg/kg bb), dan dosis III (800 mg/kg bb). Ekstrak etanolik daun bayam merah secara oral diberikan hari ke-1 sampai hari ke-67, dilanjutkan induksi diet tinggi lemak hari ke-8 sampai hari ke-67 dua jam setelah pemberian terapi. Berdasarkan hasil uji aktivitas ekstrak etanolik daun bayam merah, dosis 200 dan 400 mg/kg bb memiliki aktivitas sebagai preventif obesitas berdasarkan parameter indeks massa tubuh dan kadar glukosa darah (p

IPTEK BAGI MASYARAKAT (IbM) DESA TERONG DAN JATIMULYO DALAM PENGELOLAAN HIPERTENSI DAN DIABETES MELITUS Pradana, Dimas Adhi; Marfianti, Erlina; Trimulyaningsih, Nita
Asian Journal of Innovation and Entrepreneurship Volume 03, Issue 02, May 2018
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar

IbM aims to improve the management of hypertension and Diabetes mellitus (DM) through optimizing the Posbindu (Integrated Development Position) Position of Terong and Jatimulyo Villages. The target is the establishment of posbindu with adequate facilities and trained posbindu cadres. Other targets are the formation of IEC media on hypertension and DM and obtaining baseline clinical parameters data and after management for 3 months. Devotion is implemented within 8 months in fiscal year 2017 in cooperation with the government of Terong Village and Jatimulyo and coordinate with local health center that is Dlingo II Public Health Center. The first stage is cadre training and posbindu formation. The training was conducted by using the method of "Learning Active Cadre" (CBKA), cooperative learning, case-based learning with material on Posbindu implementation, risk factor measurement, early detection, hypertension and DM management, herbal treatment, and basic counseling techniques to play motivator healthy lifestyle. After that done early detection (baseline data) and management of hypertension and DM disease for 3 months in order to know the level of improvement of disease management and as a picture of program sustainability. To improve the knowledge of the community also provided IEC media about Posbindu and hypertension and DM. Until the end of October 2017, the Dedication team has completed several programs such as training candidate cadres posbindu, procurement of medical equipment, and the establishment of posbindu in the Village Terong and Jatimulyo. Based on clinical examination data at the opening of posbindu, monitoring and final measurement can be concluded that the implementation of Posbindu has been able to detect, monitor and improve the management of DM patients and hypertension in both villages in order to achieve controlled clinical condition.

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