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Retinitis Pigmentosa: A Case Report Delfi Delfi; Vanda Virgayanti; Rika Ramadhani Sinambela
Jurnal sosial dan sains Vol. 2 No. 2 (2022): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3090.083 KB) | DOI: 10.59188/jurnalsosains.v2i2.355

Abstract

Background : Retinitis pigmentosa is an inherited heterogeneous group of retinal disorders represented by rod photoreceptors progressive dysfunction with subsequent cone photoreceptors degeneration and the retinal pigment epithelium. The typical manifestations are progressive loss of visual field and night blindness. Purpose : The purpose of this study was to examine with the Amsler Grid on the right and left eyes, no scotomas and metamorphopsia were found. Method : The type of research is quantitative with an explanatory research approach, the sampling technique is saturated sampling with the number of subjects 76 employees and the data analysis technique uses PLS. Results : Best corrected visual acuity was 6/9 in the right eye and 6/18 in the left eye. There was arteriolar attenuation, waxy disc pallor, bone-spicule pigmentation and pigment deposits on both eyes in funduscopy exaination. The patient was diagnosed with retinitis pigmentosa. The management given was vitamin A 15.000 IU/day, DHA 1.200mg/day, and counselling about retinitis pigmentosa, progressivity, and prognosis. Conclusion : Retinitis pigmentosa caused irrreversible visual and visual field impairment. Low vision management for retinitis pigmentosa was to optimize the visual function and optimized quality of life. Genetic counselling might provide the patient and her family information of the inheritance and genetic disorders implications that could help the patient to obtain medical information regarding the disease.
Hubungan Perkuliahan Daring dengan Nyeri Kepala pada Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Angkatan 2018-2020 Sanjaya, Calvin; Pujiastuti, Raden Ajeng Dwi; Amelia, Sri; Virgayanti, Vanda
E-Jurnal Medika Udayana Vol 11 No 12 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i12.P04

Abstract

Latar belakang: Nyeri kepala merupakan keluhan umum yang sering ditemukan dengan prevalensi lebih besar dari 90%. Sekitar 26% nyeri kepala dilaporkan pada pelajar yang bukan pengguna internet dan telepon genggam, 30% pada pengguna internet, 29% pada pengguna telepon genggam, dan 29% pada pengguna keduanya. Penggunaan internet dan gadget semakin meningkat pada masa pandemi COVID-19, salah satunya dikarenakan pemberlakuan pembelajaran atau perkuliahan daring. Penggunaan gadget memiliki dampak negatif dalam aspek kesehatan seperti meningkatnya risiko kanker akibat radiasi, mata perih, nyeri leher, dan nyeri kepala. Tujuan: Untuk mengetahui hubungan antara perkuliahan daring dengan nyeri kepala pada mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Angkatan 2018-2020. Metode: Penelitian ini merupakan penelitian analitik menggunakan desain cross sectional dengan teknik simple random sampling. Subjek penelitian adalah sebanyak 90 orang mahasiswa. Hasil: Dari 90 responden, 39 orang (43,4%) mengeluhkan kadang-kadang menderita nyeri kepala, 34 orang (37,8%) mengeluhkan jarang menderita nyeri kepala, sedangkan 13 orang (14,4%) tidak mengeluhkan nyeri kepala, sisanya sebanyak 4 orang (4,4%) mengeluhkan sering nyeri kepala selama perkuliahan daring. Hasil uji statistik Fisher’s Exact menunjukkan tidak ada hubungan yang signifikan antara durasi perkuliahan daring dengan frekuensi nyeri kepala (p=0,314) dan antara frekuensi perkuliahan daring dengan frekuensi nyeri kepala (p=0,781). Kesimpulan: Tidak terdapat hubungan yang bermakna antara perkuliahan daring dengan nyeri kepala pada mahasiswa Fakultas Kedokteran Universitas Sumatera Utara angkatan 2018 sampai angkatan 2020. Kata kunci : COVID-19, gadget, nyeri kepala, perkuliahan daring
Relationship between Serum Homocysteine Levels and Manganese Superoxide Dismutase (MnSOD) on Retinal Nerve Fiber Layer (RNFL) Thickness in Diabetic Retinopathy and Non-Diabetic Retinopathy Patients: Oral Presentation - Observational Study - Resident Nurrakhmah, Rini; Delfi; Lubis, Rodiah Rahmawaty; Virgayanti, Vanda
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/w9rgsd55

Abstract

Introduction & ObjectivesDiabetic retinopathy is a visual disorder caused by abnormalities in the retina, where there is aprogressive microangiopathy characterized by damage and blockage of fine blood vessels, resultingin impaired nutrition of the retina. This study is to find out the relationship between serumhomocysteine levels and MnSOD on retinal nerve fiber layer (RNFL) thickness in diabeticretinopathy and non-diabetic retinopathy patients. MethodsThis study is an analytic observational case-control study with a total of 31 subjects for each group.3cc of venous blood samples were taken to assess the serum levels of homocysteine and MnSOD andthen analyzed by ELISA method in the integrated laboratory of the USU Medical Faculty. ResultsThere was a significant difference in Avg RNFL and Nasal RNFL thickness between the two groups(p=0.015) with the mean Avg RNFL thickness being 100.94 (SD=17.04) and the mean RNFL nasalthickness being 90.16 (SD=33.68). The highest MnSOD levels were found in non-diabeticretinopathy subjects with a mean of 142.77 (SD=101.77). There was no significant relationshipbetween homocysteine and thickness of superior RNFL (p=0.346), inferior RNFL (p=0.292),temporal RNFL (p=0.109), nasal RNFL (p=0.190). However, a significant association was foundbetween homocysteine and Avg RNFL (p=0.007). ConclusionIn the group of cases of diabetic retinopathy, a significant relationship was found between Hcy andAvg RNFL (p=0.007). An increase in serum homocysteine levels will be followed by a decrease in thethickness of the Avg RNFL.