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PENGARUH PEMBERIAN EKTRAK BIJI ANGGUR (Vitis vinifera) TERHADAP KADAR SERUM ASAM URAT PADA TIKUS PUTIH JANTAN (Rattusnorvegicus strain wistar) MODEL HIPERURISEMIA Novi Puspita Sari; dr Isbandiah; Bambang Widiwanto
Saintika Medika Vol. 12 No. 2 (2016): DESEMBER 2016
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.v12i2.5272

Abstract

Hiperurisemia adalah salah satu faktor yang menyebabkan angka kejadian infalmasi gout arthtritis akut, dan beberapa penyakit lain. Terjadinya hiperurisemia dapat di hambat dengan senyawa flavonoid seperti katekin dan epikatekin yang dapat menghambat enzim xantin oksidase senyawa tersebut terkandung dalam biji anggur (Vittis vinifera).penelitian ini bertujuan untuk Mengetahui pengaruh pemberian ekstrak biji anggur (Vitis vinnifera) terhadap serum asam urat dalam darah tikus putih (Rattusnorvegicus strain wistar) yang di induksi diet tinggi purin.. metode yang di gunakan merupakan Eksperimental, Post Test Only Control Group Design dilakukan selama 25 hari dengan menggunakan 28 ekor tikus putih jantan, di bagi dalam 1 kontrol positif dan 3 kelompok control perlakuan. Setiap kelompok di berikan diet tinggi purin 20mg/ekor selama 8hari, kemudian pada kelompok perlakuan yang diberikan ekstrak biji anggur pada kelompok 1,2, dan 3 dengan dosis berturut turut 0,9, 2,7, dan 5,4 mg selama 10 hari. Analisis data menggunakan uji One way ANOVA, post hoc bonferroni, uji korelasi dan uji regresi.hasil menunjukan one wayAnova didapatkan perbedaan yang signifikan p<0.001 Hasil uji post hoc di dapatkan perbedaan yang bermakna antara tiap-tiap kelompok perlakuan, namun uji korelasi dan regresi tidak signifikan.ddaru uji statistic dapat di simpulkan pemberian ekstrak biji anggur berpengaruh, tetapi tidak berhubungan terhadap penurunan kadar serum asam urat pada tikus model hiperurisemiaKata kunci: Asam Urat, Ekstrak Biji Anggur , Epikatekin, Katekin.
The Effect Of Counseling On The Adherence Of Therapeutic Hypertension Patients Gita Sekar Prihanti; Novi Puspita Sari; Nur Indah Septiani; Laura Putri Risty L. Tobing; Annisa Rahayu Adrian; Nihayatuz Rahayu Ayu; Muhammad Zainul Abidin; Husni Puspita Farid
Jurnal Keperawatan Vol. 11 No. 2 (2020): Juli
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (338.411 KB) | DOI: 10.22219/jk.v11i2.11943

Abstract

Failure of therapy is a result of bad adherence  medication. Non-adherence to therapy is a major factor that is suspected to result in uncontrolled blood pressure in hypertensive patients resulting in more serious complications. Therefore it is important to increase the adherence rate of treatment in patients with hypertension in the treatment process. For this reason, the need for interventions to improve  adherence  with several aspects that can be changed. This study uses One Group Pretest-Posttest Design using 100 samples. Data derived from questionnaires containing 25 items of adherence to therapy, 5 items of knowledge, 4 items of trust, 3 items of motivation, 10 items of family support with nonparametric statistical tests used were Mc Nemar test. Mc Nemar test results indicate that there is a significant difference between adherence at the pre-test and at the post-test after counseling with a significance value (p = 0,000). The results also showed that there was a difference in knowledge with a significance value (p = 0.001), motivation with a value (p = 0.031) and family support with a value (p = 0,000). The education with counseling about knowledge, trust, motivation and family support is effective in increasing compliance. There are other changeable factors such as lifestyle education, patient doctor relationships, and the use of smartphone applications for self-reported therapy can improve adherence in patients thereby minimizing therapy failure. Other educational methods that can be used besides counseling are counseling and dissemination of social media information.
Creating a Village Website as a Supporting Medium for Community Members’ Business Productivity Ferri Wicaksono; Haryoko Haryoko; Novi Puspita Sari
MITRA: Jurnal Pemberdayaan Masyarakat Vol 5 No 1 (2021): MITRA: Jurnal Pemberdayaan Masyarakat
Publisher : Institute for Research and Community Services

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitra.v5i1.1860

Abstract

The covid-19 pandemic has worsened the economy of the informal sector. Online media may serve as one solution for opening new business spaces. The main problem encountered by our partner is the lack of understanding and use of digital media as a means of promotion. This activity aims to facilitate the creation of a village website as a supporting medium to increase the productivity of the residents.The partner of this community service program is the community members of RT 01 RW 34 Padukuhan Banjeng, Kanoman, Maguwoharjo, Depok, Sleman. This activity employed the Participatory Rural Appraisal (PRA) method. The implementation of these community service activities have successfully increased four aspects of community members’ productivity: 1) human development, shown by the higher understanding and ability in using the website to promote their business and increase the value of their business products; 2) business development, demonstrated by the enthusiasm of seventeen business owners in adding content to the website and in giving access to community members to help develop their digital-based businesses; 3) environmental development, manifested in pictures of the village on the website to provide a good impression of the village; and 4) institutional development, illustrated by the initiation of a new institutional model to ensure the sustainable use of the website, as a digital media to promote the community members’businesses.