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All Journal The Journal of Pure and Applied Chemistry Research Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Borneo Journal Of Pharmascientech
Vera Fitriya Ersalena
Mataram University
Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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Characterization Of Alkaloids From The Leaves Of Psychotria Malayana Jack Of Lombok Island On The Basis Of Gas Chromatography-Mass Spectroscopy Hadi, Surya; Rahmawati, Khairul Pahmi; Asnawati, Dina; Ersalena, Vera Fitriya; Azwari, Ahmadun
The Journal of Pure and Applied Chemistry Research Vol. 3 No. 3 (2014)
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (710.542 KB) | DOI: 10.21776/ub.jpacr.%y.03.03.176

Abstract

The genus Psychotria is well known as a source of alkaloids and has contributed several novel indole-type alkaloids with quite a broad spectrum of bioactivities. This study was focused on identifying the alkaloids from the leaves of P. malayana Jack from Lombok island on the basis of Gas Chromatography-Mass Spectroscopy (GC-MS) data and the sample preparation followed acid-base extraction. The study showed that the major alkaloid contained by the leaves was hodgkinsine and other minor compounds, namely calycanthine, chimonantine, 2-ethyl-6-methylpyrazine, and 3-methyl-1,2,3,4-tetrahydro-gamma-carboline. Bioactivities of the compounds were also discussed.
Sensitivity of Bacteria causing Hospital-Acquired Pneumonia (HAP) in the Intensive Care Unit (ICU) to Empiric Antibiotics APRILIANY, FITRI; Umboro, Recta Olivia; Ersalena, Vera Fitriya; Setiawan, Deni; Cholisah, Elis
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.565

Abstract

The main therapy for the treatment of pneumonia is antibiotics. The use of antibiotics requires special attention to prevent antibiotic resistance. Therefore, it is important to know the pathogenic microorganisms that cause hospital-acquired pneumonia (HAP) infections. This study aimed to describe the sensitivity of negative-positive bacteria to empiric antibiotics in HAP patients. The study method was an analytical descriptive observational study with a cross-sectional design. Data were collected from patient medical records for the period January 2019 – December 2020. Inclusion criteria were ICU patients diagnosed with HAP, aged 15 years, with complete medical records (age, sputum culture, leukocytes, chest x-ray results), treatment history and outcome parameters (vital signs). Exclusion criteria were pregnant patients, involuntary discharge, and ICU stay of less than 48 hours. The data in this study were analyzed descriptively and Likelihood Ratio. The results of the description showed that the empiric antibiotics with sensitivity more than 70% against gram-positive bacteria causing HAP were rifampin (78%), TMP-sulfamethoxazole (78%), vancomycin (100%), and linezolid (100%) while the empiric antibiotics with sensitivity more than 70% against gram-negative bacteria was cefoperazone-sulbactam (≥75%), followed amikacin and imipenem (≥55%). Meanwhile, the empiric antibiotics had a very low sensitivity (≤ 50%) against ESLB-producing bacteria and MRSA. There is a significant relationship between age and educational level factors and bacterial growth in sputum cultures (p<0.05). Conclusion: Vancomycin and linezolid are sensitive to gram-positive bacteria, cefoperazone-sulbactam is sensitive to gram-negative bacteria and resistance to ESLB-producing bacteria and MRSA has occurred.
Hadapi pandemi covid-19 dengan perilaku hidup bersih dan sehat (PHBS) di era new normal Umboro, Recta Olivia; Apriliany, Fitri; Ersalena, Vera Fitriya
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 4 No 3 (2021)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v4i3.10195

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that can be transmitted to humans. The government of West Nusa Tenggara Province confirmed 3.082 positive cases of Covid-19 with 223 cases in Central Lombok by September 2020. Geographically, Penujak is one of villages in Central Lombok close to Lombok International Airport which is an entry point for local and international tourists. Thus, Lecturers of Division of Pharmacy, Bumigora University conducted Community Service Activity entitled “Sosialisasi Hidup Sehat dan Bersih di Tengah Pandemi Covid-19 dan Pelatihan Pembuatan Hand Sanitizer” which aims to educate societies how to start healthy life. The community service was done by socializing for healthy living and adapting to the new normal, and training to formulating hand sanitizer properly. Therefore, new insights and better understanding were gained in order to live healthily and to implement their skills to produce proper standar for hand sanitizer.
Co-Authors Ahmadun Azwari Cholisah, Elis DENI SETIAWAN Dina Asnawati Fitri Apriliany, Fitri Khairul Pahmi Rahmawati Surya Hadi Umboro, Recta Olivia