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THE EFFECTIVENESS TEST OF CIPLUKAN (Physalis angulate L.) LEAF EXTRACT ON WOUND HEALING IN MALE RABBIT (Oryctolagus cuniculus) WISTAR STRAIN Baiq Mahmudah; Recta Olivia Umboro; Fitri Apriliany
Cendekia Journal of Pharmacy Vol 5, No 2 (2021): Cendekia Journal of Pharmacy
Publisher : STIKES Cendekia Utama Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31596/cjp.v5i2.122

Abstract

  An incision wound is a wound that occurs because of a sharp incision on the skin. This wound can occur in the dermis and epidermis of the skin with a depth 0,3cm, and length of 1,5cm. If not handle properly, the cut can develop into an infected wound. Ciplukan leaves (Physialis angulata L.) contain tannins compounds. Tanin compound can accelerate wound healing with cellular mechanism. The purpose of this study is to determine the ability of ciplukan leaves extract as an alternative medicine in healing the incisions.This study is an experimental study using a completely randomized design wich using 3 treatment groups of male rabbit (Oryctolagus cuniculus) consisted of: 1st group  negative control (vaselin flava), 2nd group positive control (povidone iodine), 3rd group ciplukan leaves extract test with 3 different concentrations (15%, 30%, 45%). Wound healing was observed for 20 days.The results of the analysis using One-way ANOVA, Kruskal Wallis obtained a value of p?0.05, showed the extract of ciplukan leaves is effective in healing incisions . The healing ability equivalent to positive control with a healing time of 13 days was shown at a concentration of 45%. 
Penyuluhan Gema Cermat Obat dan Pelatihan Pembuatan Hand Sanitizer Fitri Apriliany; Recta Olivia Umboro; Vera Fitriya Ersalena
Jurnal Abdidas Vol. 2 No. 1 (2021): February, Pages 1-160
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v2i1.207

Abstract

COVID-2019 merupakan penyakit yang disebabkan oleh virus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) dan pertama kali terjadi pada Desember 2019 di Wuhan, Cina. Pemerintahan Propinsi Nusa Tenggara Barat (NTB) mengumumkan kasus pertama COVID-19 di NTB pada Maret 2020. Jumlah pasien positif yang terkonfirmasi per tanggal 16 November 2020 sebanyak 4,480 kasus yang tersebar di propinsi NTB, seperti Lombok Barat dengan kasus positif COVID-19 sebanyak 728 kasus yang disebabkan oleh tingginya riwayat perjalanan ke daerah terjangkit. Oleh karena itu, tim dosen Program Studi Farmasi Universitas Bumigora melakukan pengabdian kepada masyarakat dengan tema “Penyuluhan Gema Cermat Obat dan Pelatihan Pembuatan Hand Sanitizer” di Lembar Timur Kecamatan Lembar, Lombok Barat dengan tujuan untuk memberikan pengetahuan kepada masyarakat cara mendapatkan, menggunakan, menyimpan dan membuang obat dengan benar. Metode pelaksanaan kegiatan ini dilaksanakan melalui media promosi kesehatan dengan: a) memberikan sosialisasi gerakan masyarakat cerdas menggunakan obat dan suplemen kesehatan di masa pandemi COVID-19, b) memberikan pelatihan pembuatan produk hand sanitizer dan disinfectant yang memenuhi kaidah formulasi yang baik dari segi teknis maupun efikasi, dan c) menyediakan alat dan bahan yang diperlukan. Sehingga dapat disimpulkan bahwa masyarakat memiliki pengetahuan terkait cara mendapatkan, menggunakan, menyimpan dan membuang obat dan suplemen dengan tepat. Selain itu, masyarakat dapat praktik secara langsung dengan membuat produk akhir, berupa hand sanitizer sebanyak 20 L dan disinfectant sebanyak 25 L.
Konseling, Informasi, dan Edukasi Penggunaan Obat Antinyeri pada Manajemen Penanganan Nyeri Dismenore Remaja Recta Olivia Umboro; Fitri Apriliany; Regina Pricilia Yunika
Jurnal Abdidas Vol. 3 No. 1 (2022): February, Pages 1-227
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v3i1.525

Abstract

Manajemen penanganan nyeri dismenore diperlukan bagi remaja perempuan agar mereka mampu mengatasi keluhan nyeri dismenore secara mandiri dan menjadi lebih produktif ditengah periode menstruasinya. Tema yang diangkat pada Kegiatan Pengabdian Kepada Masyarakat (PKM) oleh Tim Dosen Fakultas Kesehatan Universitas Bumigora terkait permasalahan kesehatan reproduksi dan penanganan nyeri dismenore. Kegiatan ini menyasar pada peserta didik usia remaja di Sekolah Menengah Atas (SMA) Negeri 2 Mataram. Pelaksanaan kegiatan ini bertujuan untuk mengedukasi remaja khususnya perempuan terkait permasalahan kesehatan reproduksi dan manajemen penanganan nyeri dismenore. Metode pelaksanaan kegiatan ini dilakukan dengan mekanisme konseling, informasi, edukasi, melalui media promosi kesehatan berupa leaflet dan penyuluhan. Informasi yang tepat terkait permasalahan dismenore berdampak pada kepedulian remaja terhadap kesehatan reproduksinya. Dari kegiatan ini diketahui bahwa kebanyakan remaja perempuan di SMA Negri 2 Mataram salah dalam menginterpretasikan permasalahan nyeri dismenore yang dialaminya, sehingga manajemen penanganan nyeri dismenore tidak terlaksana dengan baik. Antusias peserta yang cukup tinggi pada sesi konseling dan diskusi menunjukkan bahwa penggunaan leaflet sebagai media promosi kesehatan sangat efektif untuk mengedukasi.
Uji Daya Anthelmintik Ekstrak Etanol Biji Petai Cina (Leucaena leucocephala, Lmk. de Wit) terhadap cacing gelang (Ascaridia galli schrank) Secara In Vitro Recta Olivia Umboro; Dedent Eka Bimmahariyanto S; Ade Sukma Hamdani
JISIP: Jurnal Ilmu Sosial dan Pendidikan Vol 3, No 1 (2019): JISIP: Jurnal Ilmu Sosial dan Pendidikan
Publisher : Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jisip.v3i1.953

Abstract

Biji petai cina (Leucaena leucocephala, Lmk. de Wit) dalam pengobatan tradisional mempunyai khasiat sebagai anthelmintik, susah tidur (insomnia), bengkak, radang ginjal, dan diabetes. Penelitian ini bertujuan untuk mengetahui efek anthelmintik ekstrak etanol biji petai cina (Leucaena leucocephala, Lmk. de Wit)terhadap cacing gelang (Ascaridia galli Schrank) secara in vitro, dan mengetahui konsentrasi ekstrak etanol biji petai cina (Leucaena leucocephala, Lmk. de Wit)yang sebanding dengan mebendazol 0,5% (b/v). Penelitian ini bersifat eksperimental yang menggunakan probit. Rancangan percobaan pada penelitian ini adalah post test dengan satu sebagai kontrol negatif yaitu NaCl 0,9%, satu sebagai kontrol positif yaitu mebendazol 0,5%, dan empat kelompok perlakuan dengan variasi konsentrasi 5%, 10%, 15% dan 20%. Data yang diperoleh berupa kematian cacing, diuji statistik uji Anava 1 jalan dengan taraf kepercayaan 95% dan metode probit. Hasil penelitian menunjukkan bahwa ekstrak etanol biji petai cina (Leucaena leucocephala, Lmk. de Wit) dengan konsentrasi 10%, 15% dan 20% (b/v) mempunyai efek anthelmintik. Konsentrasi yang setara dengan mebendazol 0,5% sebagai anthelmintik adalah 10% b/v. Perlu dilakukan penelitian tentang uji daya anthelmintik ekstrak etanol biji petai cina (Leucaena leucocephala, lmk. De wit)terhadap jenis cacing yang lain serta uji daya anthelmintik menggunakan biji petai cina (Leucaena leucocephala, lmk. De wit) dengan bentuk sediaan lain
UJI EFEKTIVITAS ANTIOKSIDANT (IC50) DAN TOKSISITAS AKUT (LD50) FRAKSI ETANOL DAUN NANGKA (Artocarpus Heterophyllus Lam.) Recta Olivia Umboro; Dedent Eka Bimmaharyanto S; Ni Komang Wijiani Yanti
JUPE : Jurnal Pendidikan Mandala Vol 5, No 6 (2020)
Publisher : Lembaga Penelitian dan Pendidikan Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jupe.v5i6.2349

Abstract

Antioxidants are needed by the body to ward of free radicals from internal and external factors. The presence of free radicals is related to human helath conditions. Back to nature lifestyle and the high cost of drugs therapy makes people preferring to use traditional medicine. Jackfruit (Artocarpus heterophyllus Lam) leaves is contain several secondary metabolites such a flavanoids, alkaloids, sapaonins, steroids and tannins. Flavanoid have an antioxidant effect.In this study, the antioxidant activity of ethanol jackfruit (Artocarpus heterophyllus Lam) leaves extract was tested using 1,1-diphenyl-2-picrylhidrazyl (DPPH) method by UV-Vis Spectrophotometry, wich Vitamin C as comparison standart. Acute toxicity test was carried out by giving oral doses of ethanol jackfruit leaf extract to 4 groups of male rats. Group I as a control (aquadest);II(100mg/30gBW);III (150mg/30gBW); IV (200mg/30gBW) were then observed for 7 days.The antioxidant activity test showed that ethanol jackfruit (Artocarpus heterophyllus Lam) leaves extract had effectiveness as an antioxidant with an IC50 value of 58.58 ppm. The data were analyzed using one-way ANOVA showing sig value 0.228, which means (P>0.005), then followed by post hoc test, an average value of 0.00,probability value is 1.000 (sig>0.005). It can be concluded that there is no significant difference between the control and the treatment dose of 100mg, and there is a significant difference in the 150mg/30gBW, 200mg/30gBW dose groups. LD50 value dosage range in 150mg and 200mg.
Evaluasi Waktu Tunggu Pelayanan Resep Obat Racikan dan Non Racikan pada Pasien Rawat Jalan di Apotek Depi Yuliana; Faizul Bayani; Dedent Eka Bimmaharyanto; Lelie Amalia Tusshaleha; Syamsul Rahmat; Meilynda Pomeistia; Recta Olivia Umboro
Bioscientist : Jurnal Ilmiah Biologi Vol 9, No 2 (2021): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v9i2.4950

Abstract

The quality of health services is still not optimal, especially in terms of patient dissatisfaction with drug services at pharmacies. A more efficient system can be built only if the waiting time evaluation has been carried out at pharmacies that provide drug prescriptions for patients. This study aims to evaluate the waiting time for prescription services at pharmacies to achieve patient satisfaction with drug services at pharmacies. In this study, Angkasa Farma's pharmacy became the subject of evaluation. The study was conducted with an observational design using descriptive analysis. The waiting time data obtained were then analyzed descriptively and compared with the minimum service standard of waiting time, this is for two types of drugs (prepared drugs and compound drugs). The results of the study based on a sample of 100 recipes and 100 non-concoction recipes are the number of recipes that meet the standards for prescription recipes as many as 37 recipes and for non-concoction recipes as many as 95 recipes. The average waiting time for concoction recipe services is 41.47 minutes and the average waiting time for non-concoction prescription services is 21.29 minutes. The average waiting time for non-concoction prescription services has met the standard, while the waiting time for blended prescription services has not met the standards according to the Regulation of the Minister of Health of the Republic of Indonesia.
EVALUATION OF ANTIDIABETICS USAGE AMONG PATIENTS WITH ULCER DIABETIC Recta Olivia Umboro; Djoko Wahyono; I Dewa Putu Pramantara
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.78

Abstract

Diabetic ulcers and gangrene are the most frequent cases of diabetes that are hospitalized. Several studies in Indonesia showed that 17-23% of the mortality rate was due to ulcers or gangrene and 15-30% was due to amputation. Blood glucose control is an integral factor which affects the successful management of diabetic ulcers. Blood glucose control can be done by the management of pharmacologic therapy, either in the form of oral antidiabetics therapy, insulin, or a combination of both. This  was a nonexperimental research with descriptive evaluative design using  a retrospective data through the medical records of patients with a T2DM diabetic ulcers diagnosis. This research was conducted in PKU Muhammadiyah Yogyakarta hospital period January 2010-December 2011. Data were analyzed with descriptive analysis and chi-square evaluation on the correlation between the type of therapy and blood glucose levels, and the correlation between blood glucose levels and the clinical outcome of patients T2DM diabetic ulcers. The results showed that the usage pattern of antidiabetics in patients with T2DM in PKU Muhammadiyah Yogyakarta hospital were insulin (46.7%), oral hypoglycemic drugs (OHD) 18.1%, the combination therapy of OHD-OHD  (20.5%), the combination therapy of insulin-OHO (13.9%), and the combination therapy of insulin-insulin  (0.8%). The type of insulin which is mostly used was rapid acting insulin (67.9%), biguanid was mostly used for OHD (68.2%). As for the combination therapy, OHD-OHD that was mostly used was biguanid-sulfonylurea (94%), the combination of insulin and OHD that was majority used was insulin-biguanid, and the combination of insulin-insulin that was mostly used was long acting-rapid acting insulin (100%). The results of chi-square analysis showed that there were significant correlation (p = 0.016) between the type of therapy and blood glucose levels, and between blood glucose levels and diabetic ulcer clinical outcome (p = 0, 00).Keywords: diabetic ulcers, antidiabetics, blood glucose levels, clinical outcomes.
Hadapi pandemi covid-19 dengan perilaku hidup bersih dan sehat (PHBS) di era new normal Recta Olivia Umboro; Fitri Apriliany; Vera Fitriya Ersalena
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 4, No 3 (2021): Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v4i3.10195

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that can be transmitted to humans. The government of West Nusa Tenggara Province confirmed 3.082 positive cases of Covid-19 with 223 cases in Central Lombok by September 2020. Geographically, Penujak is one of villages in Central Lombok close to Lombok International Airport which is an entry point for local and international tourists. Thus, Lecturers of Division of Pharmacy, Bumigora University conducted Community Service Activity entitled “Sosialisasi Hidup Sehat dan Bersih di Tengah Pandemi Covid-19 dan Pelatihan Pembuatan Hand Sanitizer” which aims to educate societies how to start healthy life. The community service was done by socializing for healthy living and adapting to the new normal, and training to formulating hand sanitizer properly. Therefore, new insights and better understanding were gained in order to live healthily and to implement their skills to produce proper standar for hand sanitizer.
RASIONALITAS ANTIBIOTIK EMPIRIS PADA PASIEN HOSPITAL ACQUIRED PNEUMONIA (HAP) DI RSUD PROVINSI NTB Fitri Apriliany; Recta Olivia Umboro; Vera Fitriya Ersalena
Majalah Farmasi dan Farmakologi Vol. 26 No. 1 (2022): MFF
Publisher : Faculty of Pharmacy, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/mff.v26i1.19426

Abstract

Penyakit infeksi masih tetap merupakan masalah kesehatan utama di Indonesia. Tingginya prevalensi penyakit infeksi di Indonesia disebabkan karena penggunaan antibiotik yang secara luas dan tidak tepat/tidak rasional. Salah satu indikator mutu program pengendalian resistensi antimikroba di rumah sakit adalah evaluasi penggunaan antibiotik secara kualitatif maupun kuantitatif. Penelitian ini bertujuan untuk mengevaluasi rasionalitas penggunaan antibiotik empiris pada pasien HAP di RSUD Provinsi NTB dan melihat pengaruh karakteritik terhadap outcome. Penelitian ini menggunakan metode penelitian deskriptif analitik dengan rancangan penelitian cross sectional dan pengambilan data secara retrospektif dari data rekam medik pasien pada Januari 2019-Desember 2020. Kriteria inklusi meliputi pasien ICU dengan diagnosa HAP, usia ≥ 15 tahun, memiliki catatan medis lengkap meliputi usia, hasil lab seperti leukosit, sputum, riwayat pengobatan, hasil pemeriksaan x-ray thorax dan parameter outcome klinik seperti TTV. Sedangkan kriteria Eksklusi yaitu pasien ibu hamil, pasien pulang paksa dan hari perawatan di ICU < 48 jam. Analisis data menggunakan chi square dan regresi logistik multivariate. Pada penelitian ini didapatkan 64 pasien HAP yang masuk dalam kriteria inklusi. Hasil analisis rasionalitas penggunaan terapi antibiotik empiris menunjukkan 17,2 % masuk kategori rasional dan tidak rasional (82,8%). Hal ini menunjukkan bahwa rasionalitas antibiotik hasil analisis hubungan rasionalitas terhadap outcome klinik adalah terdapat hubungan yang signifikan antara rasionalitas penggunaan antibiotik empiris terhadap outcome klinik (p <0,05) dan pengaruh yang signifikan LOS dan kategori gyssens terhadap outcome klinis dengan nilai p <0,05, OR = 1,73 (95% CI 1,11-3,41) dan p <0,05, OR = 2,50 (95% CI 1,22-5,14)
PENINGKATAN PEMAHAMAN PENGGUNAAN VITAMIN DAN LONG COVID DI KOTA MATARAM DAN LOMBOK BARAT Fitri Apriliany; Recta Olivia Umboro; Dedent Eka Bimmaharyanto S.
SELAPARANG Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 2 (2022): Juni
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i2.8421

Abstract

ABSTRAKPemerintah Kota Mataram dan Lombok Barat mengkonfirmasi jumlah kasus sembuh covid per 19 September 2021 6599 kasus dan 3113 kasus. Berdasarkan data tersebut akan ada sekitar enam ribuan orang di Kota Mataram dan tiga ribuan orang di Lombok Barat bisa mengalami gejala long covid-19. Minimnya pengetahuan mengenai penggunaan vitamin, long covid dan membantu program pemerintah untuk memberikan perhatian khusus pada pasien yang mengalami gejala long covid menjadi alasan dilakukan pengabdian ini. Tujuan pengabdian ini adalah memberikan pemahaman masyarakat mengenai long covid dan penggunaan vitamin pada masa pandemi covid-19. Metode pelaksanaan kegiatan ini adalah a) edukasi secara concurrent b) dialog interaktif c) diberikan pendampingan langsung memilih vitamin yang sesuai kebutuhan di Kota Mataram dan Lombok Barat yang dilakukan pada 29 - 30 Oktober 2021. Evaluasi kegiatan ini dilakukan dengan dialog interaktif dengan masyarakat secara singkat. Hasil kegiatan ini adalah telah berhasil meningkatkan pengetahuan masyarakat terhadap long covid dan penggunaan vitamin. Hal ini terlihat dari antusiasi masyarakat dengan diskusi singkat. Kata kunci: edukasi; long covid; vitamin ABSTRACTThe Mataram and West Lombok City Governments confirmed the number of recovered covid-19 cases as of September 19, 2021, with 6599 cases and 3113 cases. Based on this data, there will be six thousand people in Mataram City and three thousand people in West Lombok could experience the old symptoms of covid-19. The lack of knowledge about the use of vitamins, long covid, and assisting government programs to give special attention to patients who experience long-term symptoms of covid are the reasons for the activity. This activity aimed to determine the education about long covid and the use of vitamins during the covid-19 pandemic. This program was carried out by the following methods a) concurrent education b) interactive dialogue c) direct assistance in choosing the vitamins that are needed in Mataram City and West Lombok which be conducted on 29 - 30 October 2021. Evaluation of this activity is carried out by means of an interactive dialogue with the community. The results of this activity have succeeded in increasing public knowledge about long covid and the use of vitamins. This can be seen from the enthusiasm of the community during a short discussion. Keywords: education; long covid; vitamins