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Solanum betaceum Extract as a Protective on Spermatozoa Morphology of Mice Exposed to Lead Acetate Rima Wirenviona; Reny I'tishom; Siti Khaerunnisa; Anak Agung Istri Dalem Cinthya Riris; Nurul Fatimah Susanti; Nurul Jannatul Wahidah; Abadiyah Zakiah Kustantina
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.4594

Abstract

Environmental pollution is one of the factors that contribute to the decline in male fertility. Lead is one of six air pollutants harmful to the reproductive system. One parameter of infertility in men is an increase in reproductive function observed with decreased morphological abnormalities of spermatozoa. The purpose is to analyze the effect of giving various dosages of Solanum betaceum extract on spermatozoa morphology of mice exposed to lead acetate. This study was true experimental using a randomized post-test only control group design. The total sample was 40 male mice Balb/ C taken by simple random sampling technique. Treatment and maintenance of experimental animals for 35 days. Statistical tests showed there were significant differences with p-value 0.005. Solanum betaceum extract can be used as a protective to improve the normal morphology spermatozoa of mice that exposed to lead acetate.
The Protective Effect of Solanum betaceum Extract on Spermatozoa Vitality Exposed to Lead Acetate in Mice Rima Wirenviona; Reny I’tishom; Siti Khaerunnisa
STRADA : Jurnal Ilmiah Kesehatan Vol. 9 No. 2 (2020): November
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjik.v9i2.297

Abstract

The purpose of this study was to analyze the effect of giving various dosages of Solanum betaceum extract on the vitality spermatozoa mice exposed to lead acetate. This research was true experimental using randomized post-test only control group design. The total sample was 40 mice which were divided into 5 groups. Lead acetate used a dose of 75 mg/kg BW and various extracts of Solanum betaceum namely 100 mg/kg BW, 200 mg/kg BW and 400 mg/kg BW. Acclimatization was carried out for 7 days and continued with maintenance and treatment for 35 days. Statistical tests showed that there was a significant difference with (p=0.026). In conclusion, Solanum betaceum extract can be used as a protective to increase the vitality of spermatozoa exposed to lead acetate