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All Journal Jurnal Kedokteran Diponegoro MGMI
Edward Kurnia Setiawan Limijadi
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Medicine & Pharmacology

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HUBUNGAN NEUTROPHYL LYMPHOCYTE RATIO DENGAN C-REACTIVE PROTEIN PADA PASIEN STROKE NON HEMORAGIK Mila Niqi Itami; Banundari Rachmawati; Edward Kurnia Setiawan Limijadi; Dwi Retnoningrum
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 9, No 2 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.616 KB) | DOI: 10.14710/dmj.v9i2.27099

Abstract

Latar Belakang: Stroke merupakan suatu penyakit kegawatan, dapat menyebabkan kematian, dan juga dapat menyebabkan kecacatan. Oleh sebab itu, diperlukan indikator inflamasi berupa Neutrophyl-Lymphocyte Ratio (NLR) dari pemeriksaan hitung jenis leukosit dan C-Reactive Protein (CRP) yang merupakan reaktan tahap akut yang sensitivitasnya tinggi, dapat mendeteksi rendahnya tingkat inflamasi pada pasien stroke non hemoragik. Tujuan : Menganalisis hubungan antara NLR dan  CRP pada pasien penderita stroke non hemoragik Metode : Penelitian  ini  merupakan  penelitian  observasional  analitik  dengan rancangan  cross-sectional. Subjek  penelitian  adalah  34  pasien  stroke  non hemoragik  di  Rumah  Sakit  Nasional  Diponegoro  dan  RSUD  Dr. Adhyatma Semarang. Pengambilan sampel dilakukan dengan cara consecutive sampling yang memenuhi kriteria inklusi dan eksklusi.Uji statistik menggunakan uji Spearman. Hasil : Dari 34 sampel, didapatkan  laki-laki 18 orang  (52,94%) dan  perempuan 16 orang (47,05%), rerata usia 58,06 ± 1,33 tahun. Diperoleh hubungan positif sedang dan bermakna antara NLR dan CRP pada pasien stroke non hemoragik dengan hasil (r= 0,449; p=0,008). Simpulan : Terdapat hubungan positif sedang antara NLR dengan CRP pada pasien stroke non hemoragikKata Kunci: Neutrophyl-Lymphocyte Ratio (NLR), C-Reactive Protein (CRP), stroke non hemoragik.
The potential of dadih in increasing iron intake and its effect on Ret-He and sTfR in adolescent girls Annisa Furkaniaty; Edward Kurnia Setiawan Limijadi; Anang Mohamad Legowo; Ahmad Syauqy; Gemala Anjani
Media Gizi Mikro Indonesia Vol. 15 No. 2 (2023): Media Gizi Mikro Indonesia (MGMI)
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29238/mgmi.v15i2.2038

Abstract

Background : Dadih is a fermented milk product that contains probiotics. Probiotics can increase the bioavailability of iron so that it can help in the effort to prevent iron deficiency anemia, especially in adolescent girls. Laboratory examinations that can be done to diagnose iron deficiency anemia include reticulocyte hemoglobin equivalent (Ret-He) and soluble transferrin receptor (sTfR). Objective : This study aims to determine the effect of dadih feeding on ret-he and sTfR levels. Method : This study used a randomized pre-posttest controlled group design with 40 healthy adolescent girls aged 12-15 years who were divided into 2 groups, control (KK) and intervention (KI). The participants received dadih and a placebo as much as 100 grams with a frequency of once a day. The study was conducted for 14 days. Statistical analysis using the Wilcoxon Test, Paired T-Test, and Mann-Whitney. Result : The results showed an increase in iron and protein intake after being given dadih. Ret-He level after being given dadih decreased but there was no significant difference (p = 0.088), while sTfR level increased and there was no significant difference (p = 0.322). There was no significant difference in Ret-He and sTfR levels before and after the intervention between KK and KI (p>0.05). Conclusion : Giving dadih alone for 14 days with a frequency of once a day can increase iron and protein intake but has not had a significant effect on Ret-He and sTfR levels in healthy adolescent girl.
Co-Authors Ahmad Syauqy Anang M Legowo Annisa Furkaniaty Banundari Rachmawati Dwi Retnoningrum Gemala Anjani Mila Niqi Itami