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All Journal Pharmaciana: Jurnal Kefarmasian Pharmascience Jurnal Ilmu Kefarmasian Indonesia
Imaniar Noor Faridah
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Hubungan kualitas hidup dan persepsi pasien tentang penyakit diabetes mellitus tipe 2 dengan komplikasi Setiyo Budi Santoso; Dyah Aryani Perwitasari; Imaniar Noor Faridah; A.A Kaptein
Pharmaciana Vol 7, No 1 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (310.83 KB) | DOI: 10.12928/pharmaciana.v7i1.4699

Abstract

Kualitas hidup merupakan acuan penilaian outcome pasien diabetes mellitus tipe 2 (DMT2). Kualitas hidup pasien DMT2 dapat semakin menurun akibat komplikasi yang menyertainya. Aspek penting dalam pertimbangan intervensi peningkatan kualitas hidup adalah persepsi tentang penyakit. Tujuan penelitian ini untuk pengaruh persepsi tentang penyakit terhadap kualitas hidup pasien DMT2 dengan komplikasi.Studi potong lintang terhadap populasi terjangkau berlangsung selama Juli-September 2015 di Poliklinik Penyakit Dalam Rumah Sakit PKU Muhammadiyah Bantul. Kuesioner Short Form-36  digunakan untuk mengukur kualitas hidup dan Brief-Illness Perceptions Questionnaire untuk persepsi tentang penyakit. Analisis uji T dan Anova satu jalan dilakukan untuk mengetahui perbedaan kualitas hidup dan persepsi tentang penyakit berdasarkan karakteristik dasar pasien (jenis kelamin, umur, pendidikan, pekerjaan, kadar gula darah sewaktu, tekanan darah, dan durasi diabetes), dan pengaruh persepsi tentang penyakit terhadap kualitas hidup.Penelitian melibatkan 51 pasien DMT2 dengan komplikasi. Subyek dengan tingkat pendidikan rendah memiliki peran fisik yang lebih buruk daripada subyek dengan pendidikan menengah dan tinggi (p=0,049). Persepsi subyek yang positif dapat meningkatkan kualitas hidup pada aspek; peran fisik (p=0,032), vitalitas (p=0,032), kesehatan mental (p=0,001), dan fungsi sosial (p=0,037).            Kualitas hidup pasien DMT2 dengan komplikasi dipengaruhi oleh tingkat pendidikan dan persepsi tentang penyakit.
Uji Banding Metode Isolasi DNA Sampel FTA Card menggunakan Kit Wizard® Genomic DNA Purification, PureLink® Genomic DNA, dan Chelex-100 Dyah Aryani Perwitasari; Imaniar Noor Faridah; Yeni Alfiana Ratnasari; Kania Agustina; Ikrimah Nisa Utami; Rita Maliza
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 2 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.838

Abstract

FTA Cards are an easy way to collect blood samples, deliveries, and stores. The totalvolume of blood samples is less is needed when compared to the blood samples taken through a vein(venipuncture). The purpose of this research is a method that can be applied to isolate DNA samplesfrom FTA Cards using the Wizard® Genomic DNA Purifi cation Kit (Promega), PureLink® GenomicDNA Kits, and Chelex-100. This research was a type of experimental research, and data analysis wasshowed in qualitative and quantitative descriptively. The samples used were 16 samples of human bloodtaken using a lancet and then placed on the FTA Card, sampling was done by accidental samplingtechnique. The variations of the PureLink® Genomic DNA kits method with the addition of SDS 10%showed thin and smear DNA bands on agarose gels. Furthermore, the Chelex-100 method showed aclear DNA band. The purity data obtained varied between 1 to 1.1 and concentrations between 190 to950 ng/μl. The conclusion of this study is DNA kits method with the addition of 10% SDS and theChelex-100 method still have impurities, with the purity value of DNA was less than 1.8 and a lowconcentration to be used as a DNA template for further molecular analysis.
Predicted Factors Related to Medication Compliance and Blood Pressure in Hypertension Patients Faridah Baroroh; Imaniar Noor Faridah; Andriana Sari; Yosi Pratama Dewi
Journal of Pharmascience Vol 13, No 1 (2026): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v13i1.22750

Abstract

Nonadherence to antihypertensive medication is a key factor contributing to treatment-resistant hypertension. The main goal of hypertension treatment is to reduce morbidity and mortality by effectively lowering blood pressure. This study aimed to identify the factors influencing medication adherence and blood pressure regulation in patients with hypertension. This research utilized a retrospective cohort design. Data were gathered using the MARS questionnaire and patient medical records. The study sample consisted of hypertensive outpatients from five community health centers in the Special Region of Yogyakarta, Indonesia. Data analysis was performed using the Chi-square test. A total of 410 respondents met the inclusion criteria, with the majority being female (75.7%), 67.8% of patients adhered to their medication regimen, while 49.5% had controlled blood pressure. Difficulty remembering to take medication (p=0.010) and difficulty taking medication (p=0.049) were significantly associated with non-adherence. Age (p=0.001) and medication adherence (p=0.037) were also significantly associated with blood pressure control. The study's conclusion showed that adherence to taking medication and age are highly correlated to controlled blood pressure in hypertensive patients. Moreover, several factors related to compliance need to be identified to increase patient compliance and therapy outcomes for outpatient hypertension patients at the health center.
Co-Authors A.A Kaptein Andriana Sari Baroroh, Faridah Dyah Aryani Perwitasari Ikrimah Nisa Utami Kania Agustina Maliza, Rita MARIA BINTANG Setiyo Budi Santoso Yeni Alfiana Ratnasari Yosi Pratama Dewi