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All Journal Jurnal Penelitian Hukum - Fakultas Hukum Universitas Gadjah Mada Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Dian Widyaningrum
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Biochemistry, Genetics & Molecular Biology Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience

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VOLUME PLASMA DAN FAKTOR VIII DALAM KRIOPRESIPITAT Dian Widyaningrum; Purwanto AP; Julia Setyati
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 19, No 1 (2012)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v19i1.396

Abstract

Blood product such as cryoprecipitate required a quality control. This includes development, implementation and the standard operating procedures use of each step of the process in the production of cryoprecipitated substance to ensure that the produced product contains a minimum of 80 international units (IU) of factor VIII. Cryoprecipitation is prepared from fresh frozen plasma that thawed and centrifuge by immediate spinning the excess plasma which then removed and leaving approximately 40ml which deposit 10 mL cryoprecipitate. One unit of cryoprecipitate contain 70–80 IU/unit factor VIII, ≥100 mg/unit von Willebrand factor, fibrinogen 5–10 mg/dL. The levels of factor VIII and von Willebrand factor (VWF) lowered in individuals with blood group O compared to individuals groups with non-O blood. This research is aimed to investigate whether plasma volume are correlated with the levels of factor VIII in cryoprecipitation. In this study purposive sampling is done in which 25 bags of cryoprecipitate materials (was storage for 11 months) from all types of blood group which were taken from storage, thawed, weighed and the plasma volume measured. Factor VIII was measured by coagulometric method. The researcher used Spearman correlation test to analyze the product, with significance degree p<0.05 and confidence interval 95%. In this study it is found plasma volume which was not related to the factor VIII level in cryoprecipitattion substance (p=0.585). Mean plasma volume of the cryoprecipitated matter was 56 mL, mean factor VIII was 83.3UI. Highest factor VIII level was 160.6 UI of cryoprecipitated blood group AB and lowest factor VIII level was 21.3 UI of cryoprecipitated blood group A.
SERUM ZINC AND C-REACTIVE PROTEIN LEVELS AS RISK FACTORS FOR MORTALITY IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROME Dwi Retnoningrum; Banundari Rachmawati; Dian Widyaningrum
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 24, No 1 (2017)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v24i1.1147

Abstract

Kondisi Systemic Inflammatory Response Syndrome (SIRS) berkebahyaan terjadinya sepsis dan kegagalan multi organ. Inflamasidapat menyebabkan terjadinya redistribusi zinc ke jaringan sehingga terjadi penurunan kadar zinc plasma. Kadar CRP pada SIRSmeningkat sebagai respons peningkatan protein tahap akut. Tujuan penelitian ini untuk mengetahui apakah kadar zinc dan CRP serummerupakan faktor kebahayaan kematian di pasien SIRS. Penelitian observasional analitik dengan pendekatan kohort prospektif di 30pasien SIRS berusia 27–64 tahun. Kadar zinc serum diperiksa dengan metode atomic absorbance spectrophotometer (AAS) dan CRPserum dengan metode latex agglutination immunoassay menggunakan alat autoanaliser. Kejadian kematian subjek dinilai setelah 28hari perawatan. Data dilakukan uji statistik Chi-Kwadrat, bila tidak memenuhi maka dilakukan uji alternatif Fisher. Besarnya nilaifaktor kebahyaan dilakukan perhitungan kebahayaan relatif. Rerata kadar zinc dan CRP berturut-turut 81,24 ± 8,72 μg/dL, dan 8,13± 8,12 mg/dL. Kematian dalam 28 hari adalah 33,3%. Penelitian ini menunjukkan bahwa kadar zinc plasma < 80 μg/dL bukanmerupakan faktor kebahayaan terjadinya kematian (p=0,114), sedangkan kadar CRP ≥ 10 mg/dL merupakan faktor kebahayaanterjadinya kematian di pasien SIRS (RR=3,28, 95% CI 1,33-8,13, p=0,015). Kadar zinc plasma bukan merupakan faktor kebahayaanterjadinya kematian pada SIRS, sedangkan kadar CRP merupakan faktor kebahayaan terjadinya kematian di pasien SIRS.
IMPLIKASI PEMENUHAN HAK EKOSOB MASYARAKAT TEMAJUK TERHADAP KETAHANAN NASIONAL INDONESIA Dian Widyaningrum; Endri Ismail; Fardi Prabowo Jati; Rayvo Rahmatullah
Jurnal Penelitian Hukum - Fakultas Hukum Universitas Gadjah Mada Vol 3, No 1 (2016)
Publisher : Fakultas Hukum Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.529 KB)

Abstract

AbstractThe purpose of the research is to explain if the fulfillment of economic, social, and cultural (ecosoc) rights in Temajuk as a borderland are affecting national defense of Indonesia. In order to prove said argument, the research will describe the view of fulfillment as a reality of those rights’ fulfillment explained beforehand, review efforts from the government, and finally observe the correlation between them with the conception of national defense. Temajuk has some limitations and lack of infrastructures needed to support the optimal fulfillment of economic, social, and cultural rights, specifically to the three main sectors, namely education, health, and food, despit the guarantee of those rights by Undang-Undang Nomor 11 Tahun 2005 on Ratification of International Covenant on Economic, Social, and Cultural Rights (ICESCR). IntisariPenelitian ini berusaha menjelaskan apakah pemenuhan hak ekonomi, sosial, dan budaya (Ekosob)  masyarakat Temajuk sebagai masyarakat yang berdomisili di daerah perbatasan memberi pengaruh terhadap ketahanan nasional Indonesia. Untuk membuktikan argumen tersebut, penelitian ini akan mendeskripsikan gambaran pemenuhan sebagai sebuah realita pemenuhan hak ekosob, meninjau upaya pemenuhan hak ekosob oleh Pemerintah, dan melihat korelasi kedua hal tersebut dengan konsepsi ketahanan nasional. Temajuk memiliki keterbatasan dan kekurangan infrastruktur yang mampu menunjang proses terpenuhinyahak ekosob secara optimal, spesifik terhadap tiga sektor utama, yaitu pendidikan, kesehatan, dan pangan. Padahal hak­hak tersebut telah dijamin dalam Undang­ Undang Nomor 11 tahun 2005 Tentang Pengesahan Internasional Covenant On Economic, Social, And Cultural Rights (ICESCR).
Co-Authors Banundari Rachmawati Dwi Retnoningrum Endri Ismail Fardi Prabowo Jati Julia Setyati Purwanto AP Rayvo Rahmatullah