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All Journal Chimica et Natura Acta Jurnal Pengabdian kepada Masyarakat Journal of Pharmaceutical and Sciences. JPS (Jurnal Pharma Saintika)
Nofita, Dewi
Akademi Farmasi Dwi Farma Bukitttinggi
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Eksplorasi Aktivitas Antimikroba Bakteri Endofit Daun Betadine (Jatropha multifida L.) terhadap Patogen Staphylococcus aureus Arfiandi, Arfiandi; Fadjria , Neri; Nofita, Dewi; Rahmadini, Mutia
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.899

Abstract

Background: Antibiotic resistance has spurred the exploration of novel antibacterial agents, including endophytic bacteria from medicinal plants like Jatropha multifida L. (Betadine leaves), traditionally used as antiseptics. Objective: To assess the antibacterial activity of endophytic bacterial isolates from Betadine leaves against Staphylococcus aureus. Methods: A laboratory-based experimental study employing the paper disc diffusion method. Endophytic isolates were cultured in Nutrient Broth, and centrifuged supernatants were tested for inhibition zones compared to positive (chloramphenicol) and negative (Na.CMC) controls. Results: The endophytic isolate produced a 16.11 mm inhibition zone (moderate activity), while chloramphenicol showed 27.63 mm (strong activity). No inhibition was observed in the negative control. Conclusion: Endophytic bacteria from Betadine leaves exhibit potential as natural antibacterial agents, though their efficacy is lower than standard antibiotics. Further development requires active compound characterization and toxicity studies.
Co-Authors Arfiandi Arfiandi Arfiandi Arfiandi Arfiandi Arfiandi Arfiandi Arfiandi Arfiandi, Arfiandi Budi Setiawan Budi Setiawan Delviona Friti Rahman Fadjria , Neri Hermansyah Aziz Husnatul Mardiah Mazaya Fadhila Neri Fadjria Neri Fadjria Neri Fadjria Neri Fadjria Putri Nandinanti Rahmadini, Mutia Rahmat Dewangga Rahmiana Zein Refilda Refilda Renatalia Fika Shyntia Nofita Sari Yonrizon