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All Journal Syntax Idea Pharmaceutical And Biomedical Sciences Journal (PBSJ)
Triani Kurniawati
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Health Professions Medicine & Pharmacology Public Health

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Analisis Penggunaan Antibiotika Pada Pasien Demam Typoid Rawat Inap Di Rumah Sakit Daerah Gunung Jati Cirebon Triani Kurniawati; Khoeriyah Khoeriyah
Syntax Idea Vol 2 No 7 (2020): Syntax Idea
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/syntax-idea.v2i7.453

Abstract

Demam typoid adalah penyakit infeksi saluran pencernaan yang disebabkan oleh bakteri Salmonella Typhi. Penyakit ini merupakan salah satu penyakit yang sering terjadi, khususnya di negara berkembang. Dalam proses pengobatan penyakit demam typoid dibutuhkan antibiotika. Penggunaan antibiotika yang tidak tepat dapat meningkatkan resiko kejadian efek samping dan resistensi antibiotika. Tujuan Penelitian ini adalah mengetahui pola penggunaan antibiotika dan menganalisis rasionalitas penggunaan antibiotika pada pasien demam typoid rawat inap di Rumah Sakit Daerah Gunung Jati Cirebon periode 2018. Tinjauan Pustaka Penggunaan antibiotika disini di batasi pada tepat diagnosa, tepat indikasi, tepat obat dan tepat dosis. Penelitian ini merupakan penelitian non eksperimental yang bersifat retrospektif. Data yang diambil berasal dari rekam medik pasien demam typoid 49 pasien. Hasil penelitian menunjukan antibiotika yang sering digunakan adalah golongan sepalosporin, yaitu ceftriaxon sebanyak 55%. Dan untuk rasionalitas pengobatan adalah tepat diagnosa 100%, tepat indikasi 100% tepat obat 100% dan tepat dosis 84%.
Aktivitas Antibakteri Sediaan Masker Gel Peel Off Ekstrak Mentimun (Cucumis Sativus) Dan Tomat (Solanum Lycopersicum) Terhadap Staphylococcus Epidermidis Indri Dwi Rahasasti; Eva Luviriani; Rosellynia Calyptranti; Triani Kurniawati; Lia Handayani Rahayu
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 2 (2024)
Publisher : Pharmacy Department, Faculty of Health Sciences, UIN Syarif Hidayatullah Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i2.35117

Abstract

Acne is a disease that can be caused by bacteria, one of which is Staphylococcus epidermidis. Acne can be treated with active compounds derived from natural ingredients such as cucumbers and tomatoes. Gel masks peel off. This study aims to determine the average diameter of the inhibition zone, the difference in the average diameter of the inhibition zone, and the antibacterial activity of the peel-off from a mixture of cucumber (Cucumis sativus) and tomato  (Solanum lycopersicum) with a concentration of 5%, 10 %, 15%, 20% against  Staphylococcus epidermidis. This experimental study uses a Completely Randomized Design (CRD) consisting of one factor and 6 levels. The results showed that the average diameter of the inhibition zone of the anti-acne peel-off gel mask preparation of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10%, 15% and 20% were 16.38 mm, respectively. ; 24.88 mm; 29.88 mm and 34.88 mm. There was a significant difference in the average diameter of the inhibition zone of the peel off mixture of cucumber and tomato extracts with a concentration of 5%, 10%, 15%, and 20%; against Staphylococcus epidermidis. gel mask preparation peels off from a mixture of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10% concentration, 15% concentration and 20% concentration, namely strong, very strong, very strong and very strong.  
Co-Authors Indri Dwi Rahasasti Khoeriyah Khoeriyah Lia Handayani Rahayu Luviriani, Eva Rosellynia Calyptranti