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All Journal JURNAL KIMIA SAINS DAN APLIKASI Sebatik Syntax Idea HERBAPHARMA : Journal of Herb Farmacological Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Pharmaceutical And Biomedical Sciences Journal (PBSJ) Borobudur Pharmacy Review
Luviriani, Eva
STIKES An Nasher Cirebon
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Identifikasi Natrium Siklamat Pada Susu Bubuk Tanpa Merk Yang Beredar Di Pasar Sumber Kecamatan Sumber Kabupaten Cirebon Eva Luviriani; Indri Puspita Sari
Syntax Idea Vol 2 No 7 (2020): Syntax Idea
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/syntax-idea.v2i7.443

Abstract

Susu bubuk adalah susu berbentuk bubuk yang berasal dari susu segar yang dikeringkan. Susu bubuk mempunyai daya tahan yang lebih lama dari pada susu cair dan tidak perlu disimpan dilemari es karena kandungan uap airnya sangat rendah. Produk susu merupakan produk yang tidak terlepas dari penggunaan bahan pemanis, baik alami maupun buatan. Pemanis buatan merupakan zat yang dapat menimbulkan rasa manis atau dapat membantu mempertajam rasa manis tersebut, sedangkan kalori yang dihasilkan jauh lebih rendah dari pada gula. Tujuan penelitian ini adalah untuk mengetahui kadar Natrium Siklamat yang terkandung pada susu bubuk tanpa merk yang beredar di pasar Sumber dan mengetahui perbedaan yang signifikan antara kadar Natrium Siklamat pada susu bubuk tanpa merk dengan standar maksimum penggunaan siklamat yang telah ditetapkan oleh Peraturan Kepala Badan Pengawasan Obat dan Makanan Republik Indonesia (BPOM RI) Nomor 4 Tahun 2014. Metode yang digunakan adalah metode deskriptif kuantitatif. Metode deskriptif kuantitatif bertujuan untuk menjelaskan fenomena yang ada dengan menggunakan angka-angka untuk menggambarkan karakteristik suatu objek sebagaimana adanya. Hasil penelitian kadar natrium siklamat tertinggi didapatkan pada susu bubuk dengan kode sampel 6d yaitu sebesar 2,849 % dan kadar natrium siklamat terendah didapatkan pada susu bubuk dengan kode sampel 1a yaitu sebesar 0,109%. Hal ini menunjukkan bahwa kadar natrium siklamat pada kode sampel 6d dan 1a melebihi standar penggunaan Natrium Siklamat yang telah ditentukan oleh Kepala Badan Pengawasan Obat dan Makanan Republik Indonesia Nomor 4 Tahun 2014 yaitu sebesar 0,025%. Berdasarkan pengolahan data statistik diperoleh hasil sig. (2-tailed) 0,000 < 0,05 sehingga H0 di tolak dan H1 diterima. Hal ini menunjukkan bahwa terdapat perbedaan yang signifikan antara kadar natrium siklamat pada susu bubuk tanpa merk dengan standar maksimum penggunaan siklamat yang telah ditetapkan oleh BPOM RI Nomor 4 Tahun 2014 tentang batas maksimum penggunaan bahan tambahan pangan pemanis.
KONSENTRASI HAMBAT DAN BUNUH MINIMUM EKSTRAK ETANOL DAN METANOL KULIT DURIAN (Durio zibethinus Murr) TERHADAP SALMONELLA THYPI Rosellynia Calyptranti; Eva Luviriani; Linda Safitri
HERBAPHARMA : Journal of Herb Farmacological Vol 4 No 1 (2022): Volume 4 Nomor 1 Juni 2022
Publisher : STIKes Muhammadiyah Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55093/herbapharma.v4i1.285

Abstract

Durian (Durio zibethinus Murr) is a type of fruit that is very popular by everyone and is classified as a very abundant fruit. Compound content active in durian skin (Durio zibethinus Murr) such as alkaloids, phenols, flavonoids, tannins, and saponins can inhibit and kill bacteria that function as the antibacterial. The active compound can be obtained through the extraction process with a suitable solvent. This study aims to determine the value and difference between Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Durian Skin ((Durio zibethinus Murr.) Ethanol and Methanol Extract against Salmonella typhi. Salmonella typhi is a pathogenic bacterium that causes a large number of infections in humans in the form of typhoid fever. This study uses a completely randomized design (CDR). A factorial pattern consisting of 2 factors, namely the solvent factor and the concentration factor. Data analysis used Two Way ANOVA test to find out the comparison of the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of Durian Skin (Durio zibethinus Murr.) Ethanol and Methanol Extract against Salmonella typhi. If the data is not normally distributed then followed by a nonparametric statistical test, namely the Kruskal-Wallis test. The result of this study showed that at multilevel dilutions of Salmonella typhi which shows the number of colonies 30-300 CFU/ml at a dilution of 10-7. Durian peel ethanol extract can inhibit Salmonella typhi bacteria in the concentration of 25% and durian peel methanol extract can inhibit bacteria Salmonella typhi at a concentration of 10%. Statistical test results show that there is no difference in the Minimum Inhibitory Concentration (MIC) of Durian Skin ((Durio zibethinus Murr.) Ethanol and Methanol Extract against Salmonella typhi. (Asymp sig. >0,05).
Activity of Actinomycetes Isolated from Mangrove Segara Anakan Cilacap toward Methicillin-resistant Staphylococcus aureus (MRSA) Ari Asnani; Eva Luviriani; Oedjijono Oedjijono
Jurnal Kimia Sains dan Aplikasi Vol 23, No 1 (2020): Volume 23 Issue 1 Year 2020
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2815.136 KB) | DOI: 10.14710/jksa.23.1.1-7

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a major health concern because it causes numerous infections in both healthcare facilities and communities. The development of multiresistant against topical antibiotics has caused substantial difficulty in the management of Staphylococcus infection. Thus, this research was aimed to explore indigenous marine Actinomycetes isolated from Segara Anakan Cilacap for anti-MRSA activity. The methods used were screening anti-MRSA activity using agar-block method, production of anti-MRSA extract, extraction of the anti-MRSA extract with ethyl acetate, MIC determination of the ethyl-acetate extract, and species identification based on morphology and 16S rRNA genes. The results indicated that 14 out of 16 Actinomycetes have anti-MRSA activity. Three isolates, which were W-5B, W-5A, and P-7D, showed the highest anti-MRSA activity with the inhibition zone of 2.40 mm, 1.20 mm, and 0.80 mm, respectively. The minimum inhibitory concentration (MIC) of ethyl acetate extract from isolates W-5B, W-5A, and P-7D against MRSA were 2 mg/mL, 4 mg/mL, and 8 mg/mL, respectively. The species identification based on 16S rRNA genes indicated that Actinomycetes W-5B isolate has 92.51% similarity with Streptomyces sp. 2011. The W-5A has 94.69% similarity with Arthrobacter sp. HZ11. The P-7D has 94.79% similarity with Streptomyces clavuligerus strain A-ZN-05. The present study concludes that marine Actinomycetes from sediment mangrove in Segara Anakan Cilacap, Indonesia, has potency as anti-MRSA.
Pemanfaatan Tanaman Obat Sebagai Anti-nyamuk Dan Pemberdayaan Masyarakat Kelurahan Kaliwadas, Kecamatan Sumber, Cirebon Luviriani, Eva; Aji, Rizal Ibrahim; Haqoiroh, Haqoiroh; Hariningsih, Yetti; Azhar, Amelia Jagaddhita; Ramadhan, Alman Shafly; Hermawan, Hildan Bagus; Azizah, Wafik; Fadliyah, Malikhatul; Widiawati, Erika; Habibah, Winda Akhla; Khasanah, Uswatun; Jumaroh, Jumaroh; Nurhaeni, Nurhaeni
Jurnal Pengabdian Kepada Masyarakat (JPKM) TABIKPUN Vol. 5 No. 2 (2024)
Publisher : Faculty of Mathematics and Natural Sciences - Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpkmt.v5i2.156

Abstract

Kasus Demam Berdarah Dengue (DBD) di Desa Kaliwadas tergolong tinggi. Faktor-faktor yang menyebabkannya antara lain perkembangbiakan nyamuk Aedes aegypti, iklim, kepadatan penduduk, pengetahuan tentang cara pencegahan penyakit, dan perilaku sosial. Penggunaan obat nyamuk kimia dapat menimbulkan masalah kesehatan dan lingkungan. Tanaman serai wangi (Cymbopogon nardus L.) dapat diekstrak sebagai bahan anti nyamuk ramah lingkungan. Oleh karena itu, perlu dilaksanakan program pemberdayaan dan pemanfaatan tanaman pengusir nyamuk di Desa Kaliwadas untuk meningkatkan kesehatan dan perekonomian masyarakat melalui kegiatan penyuluhan, pelatihan budidaya serai wangi, pembuatan produk, dan pemasaran. Hasil dari program ini menunjukkan adanya peningkatan pengetahuan tentang demam berdarah, pengobatan, pencegahan penyakit, dan pemanfaatan serai wangi. Masyarakat juga mampu membudidayakan tanaman serai wangi dan membuat produk biolarvasida serta semprotan pengusir nyamuk dari tanaman tersebut.
Mangiferin Content in N-Hexane and Diethyl Ether Fractions of Mango (Mangifera indica L.) Leaves Var. Gedong Gincu : Luviriani, Eva; Calyptranti, Rosellynia; Jehan, Nabilah Nauli
Sebatik Vol. 28 No. 2 (2024): December 2024
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v28i2.2513

Abstract

Mango (Mangifera indica L.) is a tropical fruit plant with high economic value and potential as a source of phytopharmaceuticals. One notable mango variety is Gedong Gincu, originating from Majalengka Regency, West Java, which contains active compounds such as mangiferin, flavonoids, saponins, and tannins with various therapeutic effects. This study aims to compare the mangiferin content in the n-hexane and diethyl ether fractions of Gedong Gincu mango leaf extract using the Reversed-Phase High-Performance Liquid Chromatography (RP-HPLC) method. Mango leaves were extracted with ethanol, followed by fractionation using n-hexane and diethyl ether. The resulting fractions were then analyzed for mangiferin content using RP-HPLC. The weights of the n-hexane and diethyl ether fractions were 13.418 g and 8.21 g, respectively. Phytochemical screening revealed the presence of flavonoids, alkaloids, phenols, tannins, and saponins. RP-HPLC analysis showed differences in mangiferin content between the two fractions, with retention times (RT) of 1.430 minutes for the n-hexane fraction and 1.473 minutes for the diethyl ether fraction, indicating variations in solubility and interaction with the mobile phase. The RP-HPLC quantification revealed that the n-hexane fraction contained 339.5 mg/L of mangiferin, while the diethyl ether fraction contained 547.3 mg/L. This study provides valuable insights into the comparison of extraction solvents for mangiferin, which can be further utilized in the development of herbal formulations.
Kualitas mikrobiologi basis pelembab dari lemak daging Sapi metode low temperature dan bouble boiling berdasarkan angka lempeng total (ALT) Kurniawati, Triani; Luviriani, Eva; Rahasasti, Indri Dwi; Calyptranti, Rosellynia; Shafly, Alman
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.13560

Abstract

Dry skin is a problem that bothers many people. One of the causes of dry skin is skin dehydration, which can be overcome by using moisturizing cosmetics. Vaseline is a moisturizer commonly used by the public because it does not cause allergies and has good moisturizing capabilities. However, it is derived from non-renewable petroleum, necessitating alternatives. Animal fats can be used as cosmetic moisturizers and are considered safer than chemical substances like zinc oxide. According to BPOM, cosmetic products must pass safety tests such as microbial contamination, heavy metal contamination, and chemical contamination tests. Beef fat contains water and fatty acids that can create a suitable medium for microbial growth. However, temperature and water content affect microbial growth, necessitating further research on the microbiological quality of beef fat using low temperature and double boiling methods. This study aims to determine the microbiological quality of beef fat moisturizer bases using low temperature and double boiling methods through Total Plate Count (TPC) testing. This research is a pre-experimental study with a one-shot case study design. The results show that the TPC values of beef fat using low temperature and double boiling methods are each 1 x 10^4 CFU/g. This indicates that the TPC values of beef fat using low temperature and double boiling methods do not meet BPOM criteria, which is < 500 CFU/g. Keywords: Moisturizer; Beef Tallow; Low Temperature; Double Boiling; Total Plate Count.
Aktivitas Antibakteri Sediaan Masker Gel Peel Off Ekstrak Mentimun (Cucumis Sativus) Dan Tomat (Solanum Lycopersicum) Terhadap Staphylococcus Epidermidis Rahasasti, Indri Dwi; Luviriani, Eva; Calyptranti, Rosellynia; Kurniawati, Triani; Rahayu, Lia Handayani
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 6 No. 2 (2024)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i2.35117

Abstract

Acne is a disease that can be caused by bacteria, one of which is Staphylococcus epidermidis. Acne can be treated with active compounds derived from natural ingredients such as cucumbers and tomatoes. Gel masks peel off. This study aims to determine the average diameter of the inhibition zone, the difference in the average diameter of the inhibition zone, and the antibacterial activity of the peel-off from a mixture of cucumber (Cucumis sativus) and tomato  (Solanum lycopersicum) with a concentration of 5%, 10 %, 15%, 20% against  Staphylococcus epidermidis. This experimental study uses a Completely Randomized Design (CRD) consisting of one factor and 6 levels. The results showed that the average diameter of the inhibition zone of the anti-acne peel-off gel mask preparation of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10%, 15% and 20% were 16.38 mm, respectively. ; 24.88 mm; 29.88 mm and 34.88 mm. There was a significant difference in the average diameter of the inhibition zone of the peel off mixture of cucumber and tomato extracts with a concentration of 5%, 10%, 15%, and 20%; against Staphylococcus epidermidis. gel mask preparation peels off from a mixture of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10% concentration, 15% concentration and 20% concentration, namely strong, very strong, very strong and very strong.  
Co-Authors Aji, Rizal Ibrahim Ari Asnani Azhar, Amelia Jagaddhita azizah, wafik Fadliyah, Malikhatul Habibah, Winda Akhla Haqoiroh, Haqoiroh Hariningsih, Yetti Hermawan, Hildan Bagus Indri Dwi Rahasasti Indri Puspita Sari Jumaroh, Jumaroh Linda Safitri Nabilah Nauli Jehan Nurhaeni Nurhaeni Oedjijono Oedjijono Rahayu, Lia Handayani Ramadhan, Alman Shafly Rosellynia Calyptranti Sari, Indri Puspita Sembiring, Rinawati Shafly, Alman Triani Kurniawati, Triani Widiawati, Erika