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HUBUNGAN ANTARA USIA, PARITAS, PEKERJAAN DAN INDEK MASSA TUBUH DENGAN KEJADIAN PROLAP ORGAN PANGGUL BERDASARKAN SKOR PELVIC ORGAN PROLAPSE QUANTIFICATION Ermawati Ermawati; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 2, No 1 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.37-43.2018

Pelvic organ prolapse is a condition that affects the quality of women life. Pelvic organ prolapse can be caused by injury until the birth process, the aging process, the composition of the tissue in a woman, a chronic cough, or often do heavy work. Early detection of prolapse associated with Prognosis of anatomy and functional pelvic organs recovery. So we need training and learning more about Pelvic Organ Prolapse Quantification (POPQ) are clearly. The study was conducted by the method of case control study in the department of OB polyclinic of Dr. M. Djamil Padang Hospital from September 2013 until the total sample of 98 patients with 49 control groups and 49 in the case group. Analyzes were connected to assess the association of age, parity, occupation and body mass index with the incidence of pelvic organs prolapse based on POPQ. Score data are presented in tabular form. Data were tested by t-test and chi square test. If p <0.05 indicates significant results. There is a significant relationship between age and the incidence of pelvic organ prolapse (p <0.05) and OR 27,871. there is a significant correlation between parity and the incidence of pelvic organ prolapse (p<0.05) and OR 52,970. From the statistical analysis of the work, it cannot be tested statistically. From the body mass index, there is no significant relationship to the occurrence of pelvic organ prolapse (P> 0.05) and OR 1:00.Keywords: age, parity, occupation, body mass index, pelvic organs prolapse

PERBEDAAN RERATA KADAR IL-6 SERUM MATERNAL BERDASARKAN KEBERHASILAN PEMBERIAN TOKOLITIK PADA PARTUS PREMATURUS IMMINENS Joserizal Serudji; Rika Effendy; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 1, No 1 (2017)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.1.1.15-21.2017

Preterm labor needs to be prevented, one of the prevention methods is by tocolytic administration which could prevent labor thus providing a chance for lung maturation. Preterm Pregnancy is associated with increased concentrations of cytokines such as Interleukin (IL). The increasing concentration of maternal serum IL-6 can be used to predict preterm labor. This research uses the design Cross-Sectional Comparative to determine differences in means of maternal serum levels of IL-6 based on the success of the administration of a tocolytic agent on preterm labor. This study was performed on pregnant women who come to the obstetric emergency room of DR. MA. Hanafiah Batusangkar Hospital within August-November 2015. The total number which was included in statistical analysis was 34 pregnant women which were divided into 2 groups, 17 people in the group of patients who failed in tocolytic agent administration, and 17 people in the group who success in managed with a tocolytic agent. Statistical analysis was performed to analyze the validity using the T-test. There are significant differences in the average rate of maternal serum IL-6 in patients who failed to treat with a tocolytic agent and successful to treat with a tocolytic agent. Seen from the p-value 0.000. Levels of maternal serum IL-6 in patients who failed to treat with a tocolytic agent were higher than successful to treat with a tocolytic agent.Keywords: IL-6, Tocolytic, Preterm labor

Relationship between Husband's Support, Knowledge Level, and Motivation with IVA Examination Behavior in Women of Childbearing ge in Padang City Intan Firmana Putri; Ferdinal Ferry; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.50-55.2021

Background: Cancer is the second leading cause of death in the world. Cervical cancer is in the 9th position out of 35 types of cancer causing the most deaths in the world. Cervical cancer is the second highest type of cancer after breast cancer in women, which affects more than 1.4 million women worldwide. Every year more than 460,000 cervical cancer incidents occur and about 231,000 women die from the disease.Objectives: This study aims to determine the relationship between husband's support, level of knowledge and motivation, with the behavior of IVA examination in fertile aged women in the city of Padang.Methods: This research is an analytic observational study with cross-sectional comparative study approach that looks at the relationship between knowledge, motivation, and husband's support with IVA examination behavior in women of childbearing age.Results: The percentage who did not perform IVA examination was higher among respondents with low motivation compared to those with high motivation, namely 54.7% versus 45%. Statistically this difference was not significant (p> 0.05). The number of respondents who did not perform IVA examinations was higher for respondents with less husband's support, namely 32 respondents (42.1%) and more than half of respondents who did IVA examinations, namely 44 respondents (57.9%) who received less support from their husbands. Statistically this difference was significant (p <0.05).Conclusion: There is a relationship between the level of knowledge and the behavior of the IVA examination, there is no relationship between motivation and the behavior of the IVA examination and there is a relationship between the level of knowledge and the behavior of the IVA examination.Keywords: IVA, women of childbearing age, education

PERBEDAAN KADAR ASAM FOLAT SERUM PENDERITA ABORTUS SPONTAN DENGAN KEHAMILAN NORMAL Ermawati Ermawati; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 2, No 1 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.53-61.2018

Abortion is the termination of pregnancy before fetus can survive in the outside world, regardless of the cause. One cause of spontaneous abortion due to maternal nutritional factors, such as folic acid defi-ciency, lead to disruption of cell function and ends with apoptosis as well as continuing with fetal death. The study was conducted to determine differences in the levels of folic acid serum between patients with normal pregnancy and spontaneous abortion in some hospitals in West Sumatra. The study was con-ducted by the method of analytic observational comparative cross-sectional design. This research was carried out on pregnant women who come to the clinic and emergency obstetric Dr.M.Djamil hospital Padang, Batusangkar Hospital, Reksodiwiryo Hospital Padang and examinations conducted in biomed-ical laboratory medical faculty Andalas University the period August-December 2014. The total number of women included in the statistical calculation after the inclusion and exclusion criteria are met is 54 people, statistical analysis was done afterwards. The mean levels of serum folic acid is lower in sponta-neous abortion patients compared with average levels of folic acid in normal. Results of statistical anal-ysis using t-test found significant differences in the mean serum levels of folic acid group of spontaneous abortion patients with normal pregnancy group, it can be seen from p-value 0.001 (p <0.05).Keywords: Spontaneous abortion, folic acid, fetus death

PERBEDAAN KADAR ZINC SERUM PENDERITA PREEKLAMPSIA BERAT DENGAN KEHAMILAN NORMAL Ermawati Ermawati; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 2, No 1 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.44-52.2018

Preeclampsia is a major obstruction complication with increasing incidence and is associated with maternal morbidity and mortality. One theory regarding preeclampsia is the development of oxidative stress due to the benefits of pro-oxidant and anti-oxidant functions that consequently results in free radicals, active oxygen, or reactive nitrogen. The deacrease of Zinc as a cofactor of anti-oxidant enzymes is reported to be associated with an increased risk of preeclampsia. Cross sectional comparative study was conducted in Dr. M. DjamilPadangHospital, SolokDistrict Hospital, PainanDistrict Hospital, BatusangkarDistrict Hospital, and Biomedicallaboratoryof Medical Faculty of Andalas University from September 2014 to February 2015. There were 40 samples with pregnancy beyond 20 weeks which were then divided into two groups; severe preeclampsia and normal pregnancy. Serum zinc wasexamined in both groups. Serum zinc in severe preeclampsia and normal pre-stressed demonstrated a significant difference (p <0.05). The mean concentration of serum zinc in severe preeclampsia and in normal pregnancy were 0.45 ± 0.09 μg / ml and 0.78 ± 0.55 μg / ml with p = 0.02. This difference is statistically significant with p <0.005. There was a significant difference between serum zinc concentration in normal pregnant women and that in severe preeclamptic women.Keywords: severe preeclampsia, normal pregnancy, zinc serum

AKURASI INSPEKSI VISUAL ASAM ASETAT PADA LOW SQUAMOUS INTRAEPITHELIAL LESIONDIBANDINGKAN DENGAN KOLPOSKOPI DI POLI GINEKOLOGI RS M.DJAMIL PADANG Vera Nirmala; Desmiwarti Desmiwarti; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 3, No 1 (2019)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.1.9-14.2019

LSIL is a low grade cervical cancer prelesion, which through prompt diagnosis and therapy, could reduce cervical cancer incidence to 90% and reducing mortality rate for 70-80%. Colposcopy will speed up diagnosis of cervical precancer lesions thus gaining prompt management, and beneficial for patients from afar. Combination of Pap’s smear, colposcopy and biopsy is a good diagnostic package to perform in medical practice. This study was conducted using statistics diagnostic test with cross-sectional design. This research was carried out among women diagnosed with LSIL (Pap’s smear) which then colposcopy was performed in Gynaecology Clinic in Dr.M.Djamil Hospital Padang, during July to December 2014. The study was performed to determine the definitive diagnosis of LSIL (Pap’s smear). Total number of women included in this study were 70, which were divided into 2 groups: 35 women in VIA positive group and 35 in VIA negative group and statistical anal- ysis was performed using unpaired t test and chi square in SPSS 18.0 for windows. From statistical analysis using chi-square test, obtained a statistical significance between VIA test and colposcopy, it can be seen from the p-value 0.002 (p <0.05). There is a statistical significance between VIA test and colposcopy.Keywords: VIA, colposcopy, LSIL, biopsy

Correlation of Colony Lactobacillus spp. with The Incident of Overactive Bladder with OBSS Score at Pauh Primary Health Center Padang Rimbun Wahyu Gumilar; Bobby Indra Utama; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.56-62.2021

Background : Overactive bladder (OAB) is a group of urgent symptoms, with or without urgent incontinence. Research shows that some Lactobacillus spp. can be a sign of a women bladder’s good health; and found a decrease number of Lactobacillus spp. in patients with OAB. This study aims to assess the correlation of Lactobacillus spp. colony with OAB using the OABSS score at Pauh Primary Health Center, Padang.Method : This research is an analytic study with a cross sectional comparative design. The research was conducted from December 2019 to February 2020 at Pauh Primary Health Center. All women aged 20-40 years who came to Pauh Primary Health Center during the study period were included in the study. Pregnant women, having pelvic abnormalities and a history of other urinary tract diseases or having a history of hypertension and diabetes mellitus were excluded in the study. Numerical data are presented in the form of central tendency. Bivariate analysis was performed using the t-independent test if the data distribution was normal and the Kolmogorov-Smirnov test if the distribution of the data was not normally distributed.Result: There were 42 samples consisting of 21 OAB respondents and 21 normal respondents. The age of the respondents in the OAB group was 28 ± 6.8 years, while the normal group was 32 ± 7.3 years (p> 0.05). The number of Lactobacillus spp colonies in the normal group was higher than the OAB group, namely 16,389,670 ± 74,380,427.9 CU / ml compared to 15,229,634 ± 67,553,932.9 CU / ml (p> 0.05).Conclusion: There was no correlation between the number of Lactobacillus Spp colonies and the incidence of Overactive Bladder. It is necessary to do further research regarding other risk factors associated with the incidence of OAB and the causes of the decrease number of Lactobacillus spp colonies in OAB patients and the presence of other microorganisms, especially pathogenic microorganisms. Keywords: overactive bladder, Lactobacillus, OABSS score

Differences of Misoprostol and Oxytocin Effect on Cervical Ripening Imelda Yunitra; Putri Sri Lasmini; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 3, No 2 (2019)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.112-115.2019

Many studies has been done to determine the effectiveness of misoprostol and oxytocin even comparing the use of them for the induction of labor. Based on those studies, there seems to be a different effect of misoprostol and oxytocin on different phase of parturition, start from cervical ripening, uterine contrac- tion and successful labor. Compared to oxytocin as cervical ripening agent, misoprostol is more avail- able, cheaper, and effective. This study was an experimental study using pre-post control group to eval- uate the difference of misoprostol and oxytocin effect on cervical ripening. This study was conducted at RSUP DR. M. Djamil Padang and Secondary Hospital in periode of January-October 2014. Indepen- dent variable was cervical ripening using misoprostol 25 µg and oxytocin drip. Dependent variables are the event of cervical ripening and the increase of Bishop score. The average of cervical ripening using misoprostol was higher than oxytocin with 7,0968 ± 2,11904, compared to 2,5806±3,36427. This difference was significantly different with p > 0.05. It can be concluded that misoprostol is a better cer- vical ripening agent than oxytocin. Oxytocin is better given to ripe cervixKeywords: severe preeclampsia, folic acid, normal pregnancy

Correlation Between Levels of Interleukin-6 in Peritoneal Fluid With Degree of Pain, Adhesion, and Endometriosis Fertility Index Score in Endometriosis Angga Trifianda Prima; Dedy Hendry; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 5, No 2 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.193-205.2021

Introduction : Endometriosis is a benign gynecological disorder characterized by the presence of endometrial tissue and stroma outside the uterine cavity. Several theories have been proposed to explain the occurrence of endometriosis, one of which is the theory of inflammation. Endometriosis lesions can produce inflammatory cytokines, resulting in their increased levels in the peritoneal fluid. This process causes disruption in pelvic anatomy, ovarian function, prostaglandin production and growth factor production that causes pain, adhesions and infertility. Interleukin-6 (IL-6) is an important and potential inflammatory cytokine in assisting the diagnosis of endometriosis. These cytokines act as activating macrophages that can stimulate endometrial cell proliferation and modulate the secretion of other cytokines such as IL-10, IL-13 and TNF-α which augments the inflammatory process. High levels of IL-6 in the peritoneum are relatedto advanced endometriosis associated with pain, severe pelvic adhesions and embryotoxic effects leading to infertility. The effect of IL-6, both local and systemic, on the growth of endometriosis lesions and its associated symptoms is great that this cytokine is considered an important marker.Objective : This study aims to determine the relationship between local inflammatory factors (IL-6 in peritoneal fluid) obtained during laparoscopy with the degree of pain, the degree of adhesions and the correlation with the Endometriosis Fertility Index (EFI) score in endometriosis patients.Material and methods : This is a quantitative analytic research with a cross sectional study design which was conducted on 22 patients with endometriosis. Prior to the laparoscopy, historical factor (EFI score) was recorded and an assessment of the pain scale was performed by filling out a questionnaire. Intraoperatively, the peritoneal fluid was obtained. If the peritoneal fluid was found, it was taken directly with a volume of 3-5 cc using 10 cc syringe. If no fluid was found, peritoneal rinsing was performed using 0.9% NaCl fluid, then 3-5 cc fluid was aspirated using a 10 cc syringe. Subsequently, an examination was carried out using the RayBio Human IL-6 ELISA Kit. During the laparoscopy procedure, the degree of adhesion of the pelvic organs was assessed by looking at the shape and how the adhesions can be separated. Surgical factor (EFI score) was assessed intraoperatively to obtain data for the least function score, AFS endometriosis score and AFS total score. Statistical analysis was performed using paired t test and correlation test.Results : The mean age of the respondents was 34.86 ± 6.11 years, 81.8% were nulliparous, 100% were married, 100% experienced both primary and secondary infertility and 81.8% had no prior pregnancy history. In the study, it was found that IL-6 levels of peritoneal fluid were higher in patients with the degree of severe pain (P <0.05) compared to moderate with the results of 32.58 ± 7.31 pg/ml and 25.39 ± 2.70 pg/ml. IL-6 levels were found to be higher in grade three adhesions than grade two (P <0.05) with results of 32.78 ± 6.65 pg/ml and 23.86 ± 2.18 pg/ml. The mean peritoneal fluid IL-6 levels were 30.75 ± 7.01 pg/ml and the mean EFI score was 4.09 ± 2.09. The correlation of IL-6 levels in peritoneal fluid with EFI score showed a value of r = -0.448 which had moderate strength and a negative pattern, indicating that the higher the IL-6 level of peritoneal fluid, the lower the EFI score (P <0.05).Conclusion : There is a relationship between IL-6 levels of peritoneal fluid in endometriosis with the degree of pain and the degree of adhesion, where IL-6 levels were found to be higher in the degree of severe than moderate pain (P <0.05), higher in third degree adhesions than second degree ( P <0.05). There was a correlation between IL-6 levels of peritoneal fluid with EFI score (P <0.05) with a negative pattern of moderate strength analysis results (r = -0.448).Keywords: Endometriosis, Interleukin-6, Degree of Pain, Degree of Adhesion, Endometriosis Fertility Index Score

The Relationship Between Magnesium Level in Pregnancy with Gestational Diabetes Mellitus Syntia Ambelina; Dovy Djanas; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.102-111.2021

Introduction : Magnesium is one of important micronutrients in pregnancy. Pregnant women needs higher magnesium intake than non-pregnant women at similar age. Decreased blood and cellular magnesium level was related to insulin resistance.Objective : To determine relationship between mean magnesium level in pregnant women with incidence of gestational diabetes mellitus.Methods : This was quantitative analytic study using cross sectional comparative design conducted in 8 Primary Health Care in Padang and 5 General Hospital in West Sumatra. This study was done from December 2019 until March 2020. Total sample collected was 36 samples consisted of 18 pregnant mother with gestational diabetes mellitus and 18 control sample with normal pregnancy, both were in gestational age between 24-28 weeks. Statistical analysis was done using independent sample T-test.Results : Mean magnesium level of pregnant mother with gestational diabetes mellitus was 1.85 ± 0.12 mg/dL, while in control sample was 2.10 ± 0.15 mg/dL. Statistical result using independent sample T-test showed significant correlation between mean magnesium level and incidence of gestational diabetes mellitus with p <0.001 (p value <0.05)Conclusion : Magnesium level during pregnancy is related to gestational diabetes mellitus incidence.Keywords: magnesium level, pregnant women, gestational diabetes mellitus

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