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PERBEDAAN EFEK MISOPROSTOL DAN OKSITOSIN SEBAGAI PEMATANGAN SERVIKS Lasmini, Putri Sri; Yunitra, Imelda; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol 3, No 2 (2019)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aogj.3.2.119-122.2019

Abstract

Berbagai penelitian dilakukan untuk menilai efektifitas misoprostol dan oksitosin tersebut, bahkan be- berapa penelitian membandingkan pemakaian misoprostol dan oksitosin sebagai induksi persalinan, Berdasarkan bebagai penelitian tersebut terlihat bahwa tampak pengaruh yang berbeda dari misoprostol dan oksitosin pada fase perturisi mulai pematangan serviks, kontraksi uterus hingga keberhasilan persa- linan. Bila dibandingkan dengan oksitosin, maka misoprostol sebagai obat yang mudah didapatkan, mu- rah dan efektif, sebagai agen pematangan serviks dibanding dengan oksitosin. Penelitian ini merupakan penelitian eksperimental pre-post kontrol group desain untuk menilai proporsi perbedaan efek pemberi- an misoprostol dan oksitosin pada pematangan serviks, Penelitian dilakukan di RS Dr.M.Djamil Padang dan RS jejaring. Waktu penelitian mulai januari 2014 sampai bulan oktober 2014, Variabel bebas adalah pematangan serviks dengan menggunakan misoprostol 25 ?g dan drip oksitosin. Variabel tergantung adalah terjadi atau tidaknya pematangan serviks dan penilaian kenaikan Bishop skor. Rata-rata pematan- gan serviks dengan misoprostol lebih tinggi atau lebih besar dibanding dengan oksitosin yaitu 7,0968 ± 2,11904 berbanding dengan 2,5806±3,36427. Secara statistik perbedaan ini signifikan dengan p < 0,05. Misoprostol adalah agen pematangan serviks yang lebih baik daripada oksitosin, Oksitosin sebaiknya diberikan pada serviks yang matang.Kata Kunci : Preeklampsia berat, asam folat, hamil normal.
Differences of Misoprostol and Oxytocin Effect on Cervical Ripening Imelda Yunitra; Putri Sri Lasmini; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 3, No 2 (2019)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.112-115.2019

Abstract

Many studies has been done to determine the effectiveness of misoprostol and oxytocin even comparing the use of them for the induction of labor. Based on those studies, there seems to be a different effect of misoprostol and oxytocin on different phase of parturition, start from cervical ripening, uterine contrac- tion and successful labor. Compared to oxytocin as cervical ripening agent, misoprostol is more avail- able, cheaper, and effective. This study was an experimental study using pre-post control group to eval- uate the difference of misoprostol and oxytocin effect on cervical ripening. This study was conducted at RSUP DR. M. Djamil Padang and Secondary Hospital in periode of January-October 2014. Indepen- dent variable was cervical ripening using misoprostol 25 µg and oxytocin drip. Dependent variables are the event of cervical ripening and the increase of Bishop score. The average of cervical ripening using misoprostol was higher than oxytocin with 7,0968 ± 2,11904, compared to 2,5806±3,36427. This difference was significantly different with p > 0.05. It can be concluded that misoprostol is a better cer- vical ripening agent than oxytocin. Oxytocin is better given to ripe cervixKeywords: severe preeclampsia, folic acid, normal pregnancy
Pemeriksaan Pertumbuhan Janin Laksmi Maharani; Denny Dhanardono; Irmiya Rachmiyani; Imelda Yunitra
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 9 : Oktober (2023): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Antenatal care is a crucial activity that should be done periodically in all pregnant women. The goal of antenatal care is to monitor the growth and development of the fetus and to prepare the women to successfully deliver healthy baby. Monitoring fetal growth is important to detect fetal growth restriction condition promptly and make any intervention needed as soon as possible to avoid further complications. The measurement can be done conventionally by measuring the fundal height.   On the other hand, ultrasound scanning to measure fetal biometry is more accurate to do so. A community serviced activity has been performed to monitor fetal growth at Kelurahan Ciangsana to 24 pregnant women, which showed a quite good result.
Dilema Managemen Tatalaksana Persalinan pada Anencephali sebagai Janin Letal Yunitra, Imelda; Wiranti, Hervi; Nirmalasari, Rully Ayu; Mayasari, Atut Cicih; Dhanardono, RM Denny; Maharani, Laksmi
Jurnal Biomedika dan Kesehatan Vol 8 No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

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Abstract

Anencephaly is a congenital anomaly of the central nervous system, caused by a disruption in brain and skull development of a fetus, which includes the disruption of the cerebral hemispheres, cerebellum, spinal cord, and pyramidal tract. This is a lethal condition that most fetuses born with this condition cannot survive after being delivered. The prevalence of this condition is 1 in 1000 deliveries. Early detection through prenatal ultrasound testing is essential to make a correct and precise plan for managing the pregnancy and delivery process, thus avoiding potential maternal complications. We reported a 33-year-old pregnant woman who was diagnosed with having anencephalic fetus at 24 weeks of pregnancy. The patient has been informed about this condition and offered a termination, but she refused to do so and is willing to continue the pregnancy. Induction of labor was planned at 40 weeks of pregnancy, but the process was impaired, so a cesarean section was performed to save the mother. The baby was delivered with anencephaly, as shown by the ultrasound result, and died 2 days after being delivered. The mother recovered well and was given education about the importance of folic acid intake for the next pregnancy. Conclusion of this case was labor management of anencephalic fetus was planned according to medical indication, with a special individual approach due to the obstetric condition. Yet, the delivery method should be based more on the mother's condition rather than the baby's, including the maternal emotional factor.
Differences of Misoprostol and Oxytocin Effect on Cervical Ripening Yunitra, Imelda; Lasmini, Putri Sri; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 3 No. 2 (2019)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.112-115.2019

Abstract

Many studies has been done to determine the effectiveness of misoprostol and oxytocin even comparing the use of them for the induction of labor. Based on those studies, there seems to be a different effect of misoprostol and oxytocin on different phase of parturition, start from cervical ripening, uterine contrac- tion and successful labor. Compared to oxytocin as cervical ripening agent, misoprostol is more avail- able, cheaper, and effective. This study was an experimental study using pre-post control group to eval- uate the difference of misoprostol and oxytocin effect on cervical ripening. This study was conducted at RSUP DR. M. Djamil Padang and Secondary Hospital in periode of January-October 2014. Indepen- dent variable was cervical ripening using misoprostol 25 µg and oxytocin drip. Dependent variables are the event of cervical ripening and the increase of Bishop score. The average of cervical ripening using misoprostol was higher than oxytocin with 7,0968 ± 2,11904, compared to 2,5806±3,36427. This difference was significantly different with p > 0.05. It can be concluded that misoprostol is a better cer- vical ripening agent than oxytocin. Oxytocin is better given to ripe cervixKeywords: severe preeclampsia, folic acid, normal pregnancy
Self-Sampling for Cervical Cancer: a Scoping Review Murthi, Aditya Krishna; Kurniawan, Yani; Yunitra, Imelda; Halim, Catherine; Sisca, Sisca
Jurnal Indonesia Sosial Sains Vol. 6 No. 8 (2025): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v6i8.1839

Abstract

Cervical cancer remains a major global health concern, particularly in low- and middle-income countries (LMICs), where barriers such as limited healthcare access, cultural stigma, and logistical challenges hinder routine screening. Human papillomavirus (HPV) self-sampling has emerged as a promising alternative to clinician-collected sampling, offering the potential to improve screening coverage and reduce the burden of cervical cancer. This scoping review aims to synthesize current evidence on the feasibility, effectiveness, and acceptability of HPV self-sampling, with a focus on its impact on screening uptake, psychological outcomes, and diagnostic accuracy. Following the PRISMA-ScR guidelines, a systematic search was conducted across PubMed, Google Scholar, and Scopus, resulting in the inclusion of five studies: four randomized controlled trials and one umbrella review. Findings indicate that self-sampling reduces anxiety associated with cervical screening, improves participation among underserved populations, and demonstrates high diagnostic concordance with clinician-collected samples. Behavioral interventions, such as pay-it-forward models, show potential to enhance sample return and feedback rates. However, challenges remain regarding effective triage strategies for HPV-positive cases, especially in resource-limited settings. The review supports the integration of self-sampling into national screening programs, emphasizing the need for culturally tailored approaches and continued research on cost-effective triage methods.
GANGGUAN MENSTRUASI TENAGA KESEHATAN PEREMPUAN PUSKESMAS KOTA TEGAL TERHADAP LAMA PERGANTIAN JAM KERJA DAN STRES KERJA Dhanardono, Denny; Ekomurtomo, Indrawan; Wiranti, Hervi; Yunitra, Imelda; Fujasari, Ergita; Restigaluh, Kirana
JURNAL PENELITIAN DAN KARYA ILMIAH LEMBAGA PENELITIAN UNIVERSITAS TRISAKTI Vol. 11 No. 1 (2026): Januari 2026
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/pdk.v11i1.25459

Abstract

Latar Belakang: Gangguan menstruasi merupakan salah satu masalah kesehatan reproduksi yang umum terjadi pada perempuan usia produktif, termasuk di kalangan tenaga kesehatan. Stres kerja dan sistem kerja shift yang panjang dapat memengaruhi keseimbangan hormon dan memicu gangguan menstruasi. Tujuan: Mengetahui hubungan lamanya pergantian jam kerja dan stres kerja terhadap gangguan menstruasi pada tenaga kesehatan perempuan di Puskesmas Kota Tegal. Metode: Penelitian ini merupakan studi analitik observasional dengan desain potong lintang. Sebanyak 162 pekerja kesehatan wanita berpartisipasi dengan mengisi kuesioner terstruktur yang mencakup data sosiodemografis, jam kerja, stres terkait pekerjaan (SDS-30), dan pola menstruasi. Data dianalisis menggunakan uji Chi-square dengan tingkat signifikansi 0,05. Hasil: Sebanyak 55,6% responden mengalami gangguan menstruasi. Tidak terdapat hubungan yang bermakna antara lamanya pergantian jam kerja (p=0,103) dan stress kerja (p=0,078) dengan gangguan menstruasi. Faktor sosiodemografi seperti usia, status pernikahan, riwayat kehamilan, dan usia menarche juga tidak menunjukkan hubungan signifikan. Kesimpulan: Tidak terdapat hubungan yang bermakna secara statistik antara lamanya pergantian jam kerja maupun stres kerja dengan kejadian gangguan menstruasi. Penelitian ini menunjukkan bahwa gangguan menstruasi bersifat multifaktorial dan kemungkinan dipengaruhi oleh variabel lain seperti jenis pekerjaan, shift malam, dan gaya hidup.