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All Journal Jurnal Kedokteran Diponegoro Jurnal Biomedika dan Kesehatan Andalas obstetrics and gynecology journal
Yunitra, Imelda
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Case Report: Diagnosis and Management of Body Stalk Anomaly Yunitra, Imelda; Yusrawati, Yusrawati
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 2 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i2.41097

Abstract

Background: Body stalk anomaly is a rare and severe malformation syndrome , occurring only 1 of 10.000 live births. The patholphysiology and trigger factor of body stalk anomaly are still unknown and characterized by : abdominal wall defects, thoracoo and abdominochisis, Severe kyphoscoliosis, a truncated or absent umbilical cord, and limb irregularities are characteristic features of body stalk anomaly. Potential factors contributing to this condition encompass early amnion rupture due to direct mechanical pressure or the presence of amniotic bands, vascular disruption in the early embryo, or an abnormality in the germinal disk.Early antenatal diagnosis is crucial for patient management despide the low life expectancy, and cooperative teamwork is needed to investigation the abdnormalities encountered at birth. the chromosomal testing is performed for congemital anomaly investigation. Case Presentation: We describe a case of body stalk anomaly that was identified through antenatal ultrasound evaluation during the initial visit. The findings were confirmed during the fetomaternal ultrasound examination, the finding were as follows : a single live fetus in utero in transverse lie position, absent amniotic fluid, scoliosis of the vertebrae, an abdominal wall defect, visceral organs (liver and intestines) protruding from the defect. The patient underwent elective caesarean section due to the tranverse lie positionof the fetus and severe oligohydramnios. The baby was born weigh in 2700 grams, measuring 30 cm in length, and with apgar score of 1/1. The observed congenital anomaly include : the placental adhering to the fetal abdomen, absence of an umbilical, visceral organs ( liver, spleen, small intestine, and large intestine ) protruding from a large abdominal wall defect. Both upper limbs are normal , the right lower limb has short femur with tibia and fibula, four toes and a band from the right foot to the pelvis. The left limb is not formed, with low set ears, placental thicketing, a singke umbilical artery, and undeveloped anus. Conclusion: Ultrasound examination is primary diagnostic tool to detect Body Stalk Anomaly ( BSA) ,with ultrasound , doctors can visualize the internal structure of the fetus and conditions intra uterine. Diagnosis of chromosomal abnormalities in fetus is one of most important challrnge in perinatology.
Dilema Managemen Tatalaksana Persalinan pada Anencephali sebagai Janin Letal Yunitra, Imelda; Wiranti, Hervi; Nirmalasari, Rully Ayu; Mayasari, Atut Cicih; Dhanardono, RM Denny; Maharani, Laksmi
Jurnal Biomedika dan Kesehatan Vol 8 No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

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Abstract

Anencephaly is a congenital anomaly of the central nervous system, caused by a disruption in brain and skull development of a fetus, which includes the disruption of the cerebral hemispheres, cerebellum, spinal cord, and pyramidal tract. This is a lethal condition that most fetuses born with this condition cannot survive after being delivered. The prevalence of this condition is 1 in 1000 deliveries. Early detection through prenatal ultrasound testing is essential to make a correct and precise plan for managing the pregnancy and delivery process, thus avoiding potential maternal complications. We reported a 33-year-old pregnant woman who was diagnosed with having anencephalic fetus at 24 weeks of pregnancy. The patient has been informed about this condition and offered a termination, but she refused to do so and is willing to continue the pregnancy. Induction of labor was planned at 40 weeks of pregnancy, but the process was impaired, so a cesarean section was performed to save the mother. The baby was delivered with anencephaly, as shown by the ultrasound result, and died 2 days after being delivered. The mother recovered well and was given education about the importance of folic acid intake for the next pregnancy. Conclusion of this case was labor management of anencephalic fetus was planned according to medical indication, with a special individual approach due to the obstetric condition. Yet, the delivery method should be based more on the mother's condition rather than the baby's, including the maternal emotional factor.
Differences of Misoprostol and Oxytocin Effect on Cervical Ripening Yunitra, Imelda; Lasmini, Putri Sri; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 3 No. 2 (2019)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.112-115.2019

Abstract

Many studies has been done to determine the effectiveness of misoprostol and oxytocin even comparing the use of them for the induction of labor. Based on those studies, there seems to be a different effect of misoprostol and oxytocin on different phase of parturition, start from cervical ripening, uterine contrac- tion and successful labor. Compared to oxytocin as cervical ripening agent, misoprostol is more avail- able, cheaper, and effective. This study was an experimental study using pre-post control group to eval- uate the difference of misoprostol and oxytocin effect on cervical ripening. This study was conducted at RSUP DR. M. Djamil Padang and Secondary Hospital in periode of January-October 2014. Indepen- dent variable was cervical ripening using misoprostol 25 µg and oxytocin drip. Dependent variables are the event of cervical ripening and the increase of Bishop score. The average of cervical ripening using misoprostol was higher than oxytocin with 7,0968 ± 2,11904, compared to 2,5806±3,36427. This difference was significantly different with p > 0.05. It can be concluded that misoprostol is a better cer- vical ripening agent than oxytocin. Oxytocin is better given to ripe cervixKeywords: severe preeclampsia, folic acid, normal pregnancy
Co-Authors Atut Cicih Mayasari Dhanardono, RM Denny Hafni Bachtiar Laksmi Maharani Putri Sri Lasmini, Putri Sri Rully Ayu Nirmalasari, Rully Ayu Wiranti, Hervi Yusrawati Yusrawati