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Tingkat Pengetahuan, Sikap, dan Persepsi Mengenai Epilepsi antara Masyarakat Pedesaan dan Perkotaan di Padang Hendra Permana
Health and Medical Journal Vol 3, No 1 (2021): HEME January 2021
Publisher : Universitas Baiturrahmah

Introduction: The Knowledge, perception and attitude about epilepsy in developing country, including Indonesia is still low. These problems can cause stigma and discrimination to the patient. Society still has the view that epilepsy is not a disease, but because of the inclusion of evil spirits, possessions, witches or a curse. Furthermore, the information gap between rural and urban society could contribute to the issues. Aims: This study was aimed to explore the knowledge, perception and attitude about epilepsy between rural and urban society in Padang. Method: This study used cross sectional comparative design. This study was conducted on February – June 2018 at Ulak Karang (urban) and Bungus (rural) public health center. The subjects of this study were 140 visitors of both public health centers. The inclusions criteria of this study was all visitors ≥ 17 years old and the exclusion criteria was all incomplete data. Data was taken by using questionnaire with 13 close questions. These data was analyzed with SPSS 22. Mannwhitney tests and Chi Square test were used to compare the knowledge, perception and attitude from the two groups. A P value below 0.05 was considered asstatistically significant. Result: From demographic data, there were no significant differences between urban and rural communities. In terms of knowledge about epilepsy, there are significant differences regarding the causes of epilepsy with a value of p = 0.002. In addition, perceptions of epilepsy stigma that differed significantly in urban and rural communities were regarding malformations in epilepsy patients with p = 0.046. As for community attitudes towards epilepsy patients, there were no significant differences between urban and rural areas Conclusion: Stigma is a frightening thing for people with epilepsy, because it can interfere with their social interactions and also reduce the opportunity to get a job and also the opportunity to get married.

Hubungan Kadar Magnesium Serum Dan Hba1c dengan Severitas Neuropati Diabetik Andi Fadilah Yusran; Yuliarni Syafrita; Hendra Permana
Jurnal Ilmu Kedokteran Vol 16, No 1 (2022): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v16i1.2022.22-29

Low magnesium levels are known to be associated with increased risk of diabetes mellitus and its complications. In addition, HbA1c levels are also known to have a correlation with further diabetes complications such as diabetic neuropathy. Diabetic neuropathy is the most common microvascular complication in diabetes mellitus, whose incidence is associated with disability and mortality rates in diabetic patients. This study aimed to assess the correlation between serum magnesium levels and HbA1c with the severity of diabetic neuropathy. This was a cross-sectional study. Severity of diabetic neuropathy is classified according to the Baba's Diabetic Neuropathy Classification (BDC). All subjects were examined for serum magnesium and HbA1C levels. This study consisted of 46 diabetes mellitus subjects, with 69.6% of the subjects suffering from diabetic neuropathy. The average magnesium level in this study was 1.87 mg/dl ± 0.245 and the median HbA1c level was 8.6 %. There was no significant correlation between serum magnesium levels and HbA1c with the incidence and severity of diabetic neuropathy (p>0.05). However, there was a significant negative correlation between magnesium levels and HbA1c levels in diabetic neuropathy patients.

The Relationship between CC Ligand 5 Plasma Levels and Modic Changes in Low Back Pain Patients’ Severity Firstisa Nuzulia Krinseani; Syarif Indra; Hendra Permana
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 10 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i10.590

Background: Low back pain (LBP) is one of the global health problems. The most common cause of LBP is disc degeneration. Modic changes (MC) are the most common MRI features in patients with disc degeneration. As a result of cartilage and disc tissue damage, CCL 5 is released and modulates pain responses in the dorsal root ganglion. This study aims to determine the relationship between CCL5 levels and the description of Modic changes on MRI with pain levels in patients with low back pain. Methods: This study is a cross-sectional study. The research subjects were LBP patients who were treated at the Neurology Polyclinic, Dr. M. Djamil General Hospital, Padang, in the range of March 2021-December 2021, who meets the inclusion and exclusion criteria. Subjects will be taken blood to assess CCL5 plasma levels, pain assessment using the McGill Pain Questionnaire, and undergo an MRI examination. Results: A total of 52 subjects consisted of 23 men and 29 women with an age range of 34-77 years. Most of the Modic changes were found in the type 2 group. Based on the pain scale, there were two groups with mild pain and moderate pain. On examination of plasma CCL 5 levels, the median value of plasma CCL5 levels was 303,271 ng/L. There was a significant relationship between plasma CCL5 levels and pain levels in patients with low back pain (p = 0.004). There was no significant relationship between Modic changes and the severity of pain. Conclusion: Plasma CCL5 levels are associated with pain levels in patients with low back pain, while Modic changes are not associated with pain severity.

The Relationship between CC Ligand 5 Plasma Levels and Modic Changes in Low Back Pain Patients’ Severity Firstisa Nuzulia Krinseani; Syarif Indra; Hendra Permana
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 10 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i10.590

Background: Low back pain (LBP) is one of the global health problems. The most common cause of LBP is disc degeneration. Modic changes (MC) are the most common MRI features in patients with disc degeneration. As a result of cartilage and disc tissue damage, CCL 5 is released and modulates pain responses in the dorsal root ganglion. This study aims to determine the relationship between CCL5 levels and the description of Modic changes on MRI with pain levels in patients with low back pain. Methods: This study is a cross-sectional study. The research subjects were LBP patients who were treated at the Neurology Polyclinic, Dr. M. Djamil General Hospital, Padang, in the range of March 2021-December 2021, who meets the inclusion and exclusion criteria. Subjects will be taken blood to assess CCL5 plasma levels, pain assessment using the McGill Pain Questionnaire, and undergo an MRI examination. Results: A total of 52 subjects consisted of 23 men and 29 women with an age range of 34-77 years. Most of the Modic changes were found in the type 2 group. Based on the pain scale, there were two groups with mild pain and moderate pain. On examination of plasma CCL 5 levels, the median value of plasma CCL5 levels was 303,271 ng/L. There was a significant relationship between plasma CCL5 levels and pain levels in patients with low back pain (p = 0.004). There was no significant relationship between Modic changes and the severity of pain. Conclusion: Plasma CCL5 levels are associated with pain levels in patients with low back pain, while Modic changes are not associated with pain severity.

Hubungan Kualitas Tidur dengan Tekanan Darah pada Lansia di Kecamatan Kuranji Kota Padang Dea Rika Putri Purba; Restu Susanti; Rika Susanti; Hendra Permana; Arina Widya Murni; Eldi Sauma
Jurnal Ilmu Kesehatan Indonesia Vol 4 No 3 (2023): September 2023
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v4i3.1077

Latar Belakang: Peningkatan angka harapan hidup yang terjadi menyebabkan peningkatan penyakit degeneratif pada lansia, salah satunya hipertensi. Proses penuaan pada lansia menyebabkan lansia mengalami beberapa perubahan fisiologi salah satunya fisiologi tidur, struktur, durasi, kedalaman, dan kontinuitas tidur akan pada lansia. Kualitas tidur buruk dapat menyebabkan meningkatnya tekanan darah melalui aktivasi sistem saraf simpatis. Objektif: Mengetahui hubungan kualitas tidur dengan tekanan darah pada lansia di kecamatan Kuranji Kota Padang. Metode: Jenis penelitian ini merupakan penelitian analitik dengan desain studi cross-sectional. Sampling from the population using consecutive sampling techniques in the elderly recorded in Kuranji District, Padang City and conducting interviews with PSQI questionnaires and blood pressure measurements directly on the samples. Hasil: Terdapat sebanyak 67 responden (69,1%) memiliki kualitas tidur buruk dan 30 responden (36,1%) memiliki kualitas tidur baik. Sebanyak 62 responden (63,9%) mengalami hipertensi. Hasil analisis data dengan SPSS menggunakan uji Chi-square diperoleh nilai p = 0,000 < 0.05 ( Î± = 0,05 ). Kesimpulan: Terdapat hubungan antara kualitas tidur dan tekanan darah pada lansia di Kecamatan Kuranji Kota Padang sehingga H1 ditolak.

ABNORMALITAS INTERPRETASI ELEKTROKARDIOGRAM MENURUT GAMBARAN NEUROIMAGING PADA STROKE HEMORAGIK Dedi Sutia; Syarif Indra; Hendra Permana; Andi Fadilah Yusran Putri; Ribka Ankashima Sembiring
NEURONA Vol 37 No 2 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i2.110

ELECTROCARDIOGRAM INTERPRETATION ABNORMALITIES ACCORDING TO NEUROIMAGING IN HEMORRHAGIC STROKEABSTRACTIntoduction: Stroke is the third leading cause of death in the world (about 30% of cases of stroke are hemorrhagic). Cardiovascular disease has correlation to stroke, as risk factor and complication leading to mortality.Aim: To describe electrocardiogram (ECG) interpretation abnormalities in acute hemorrhagic stroke patients.Methods: This retrospective descriptive study evaluated the archive data of acute hemorrhagic stroke patients neurology ward General Hospital of Dr. M. Djamil Padang who according to inclusion and exclusion criteria since 1st February to 30th September 2018. The samples were an electrocardiography of acute hemorrhagic stroke patients. Data were analyzed by univariate analysis using statistical package for the social science (SPSS) software 23.Results: This study administered 81 subjects; 34 subjects (41.98%) were male and 47 subjects (58.02%) were female. The highest age group was 61-70 years old (29.63%). Most common risk factor was hypertension (66.68%). There were 40 intracerebral hemorrhage (ICH) subjects (49.38%) and 7 subarachnoid hemorrhage (SAH) subjects (11.11%) who had ECG interpretation abnormality. Both groups had left ventricle hypertrophy (LVH) as the most common ECG interpretation abnormality (ICH: 40.76%, SAH: 3.73%). The only one of ICH with secondary SAH subject had ECG interpretation abnormality.Discussion: Abnormal electrocardiogram interpretation were more common than normal electrocardiogram interpretation in acute hemorrhagic stroke subjects. Left ventricle hypertrophy (LVH) is the most common ECG interpretation abnormality in acute hemorrhagic stroke subjects.Keywords: ECG abnormalities, hemorrhagic stroke, intracerebral hemorrhage, subarachnoid hemorrhageABSTRAKPendahuluan: Stroke adalah penyebab kematian ketiga terbanyak di dunia (sekitar 30% kasus stroke adalah tipe stroke hemoragik). Masalah kardiovaskular berhubungan erat dengan stroke, sebagai faktor risiko dan komplikasi yang mengakibatkan mortalitas.Tujuan: Penelitian ini mendeskripsikan temuan abnormalitas interpretasi elektrokardiogram (EKG) menurut gambaran neuroimaging pada pasien stroke hemoragik akut.Metode: Penelitian deskriptif retrospektif ini mengevaluasi arsip data pasien stroke hemoragik akut di ruangan rawat inap neurologi ruangan rawat inap neurologi Rumah Sakit Umum Pusat Dr. M. Djamil, Padang yang sesuai dengan kriteria inklusi dan eksklusi sejak 1 Februari hingga 30 September 2018. Sampel penelitian adalah gambaran EKG pasien stroke hemoragik akut. Data dianalisis dengan analisis univariat menggunakan software statistical package for the social science (SPSS) 23.Hasil: Pada penelitian ini didapatkan 81 subjek; 34 subjek (41,98%) adalah laki-laki dan 47 subjek (58,02%) adalah perempuan. Kelompok usia subjek terbanyak adalah kelompok usia 61-70 tahun (29,63%). Faktor risiko terbanyak adalah hipertensi (66,68%). Ada 40 subjek perdarahan intraserebral (PIS) (49,38%) dan 7 subjek perdarahan subaraknoid (PSA) (11,11%) yang memiliki abnormalitas interpretasi EKG. Kedua kelompok subjek memiliki left ventricle hypertrophy (LVH) sebagai abnormalitas interpretasi EKG terbanyak (PIS:40,76%, PSA: 3,73%) Ada 1 subjek PIS dengan PSA sekunder (1,23%) dan subjek tersebut memiliki abnormalitas interpretasi EKG. Ada 14 subjek yang memiliki LVH sebagai abnormalitas interpretasi EKG dari 30,90% yang memiliki perdarahan stroke di kapsula interna (lokasi perdarahan terbanyak). Jumlah subjek dengan interpretasi EKG normal terbanyak adalah subjek dengan perdarahan di talamus.Diskusi: Left ventricle hypertrophy (LVH) adalah temuan abnormalitas interpretasi EKG terbanyak yang ditemukan pada subjek perdarahan stroke di kapsula interna (lokasi perdarahan terbanyak). Jumlah subjek dengan interpretasi EKG normal terbanyak adalah subjek dengan perdarahan di talamus.Kata kunci: Abnormalitas EKG, perdarahan intraserebral, perdarahan subarakhnoid, stroke hemoragik

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