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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Natural
Misrahanum Misrahanum
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Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Energy Immunology & microbiology Medicine & Pharmacology Neuroscience Physics

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UJI FITOKIMIA DAN AKTIVITAS ASAM SUNTI (Averrhoa bilimbi L.) SEBAGAI ANTIMIKROBA Misrahanum Misrahanum; Nia Ayuningrum; Hira Helwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (168.221 KB) | DOI: 10.36387/jiis.v7i1.854

Abstract

Many plants that have potential as antimicrobial agents are found in Indonesia. One of them is bilimbi (Averrhoa bilimbi L.) which comes from the Oxalidaceae family. People in Aceh usually process the fruit into asam sunti. This research was conducted to determine the phytochemical, characterization simplicia, extract, and antimicrobial activity of the asam sunti methanol extract. Phytochemical tests were done using two methods that are the addition of reagents and thin-layer chromatography (TLC). Phytochemical results in each test showed that the asam sunti methanol extract contained alkaloids, flavonoids, tannins, saponins, steroids, and triterpenoids. The water content, water-soluble extract content, ethanol-soluble extract content and total ash obtained was 4,6; 46,6; 54,16 and 39,6% for simplicia and extract respectively, with a value of 22; 42.6; 47.6, and 10.3%. Antimicrobial activity testing used a diffusion well at various concentrations 10; 20; 30; 40 and 50%. The smallest inhibition zone results were obtained at a concentration of 10% with a range of the inhibition zone is 7.43-7.86mm. The biggest antimicrobial activity was found at a concentration of 50% with an inhibition zone of 17.76; 10.63 and 8.7 mm for bacteria and fungi, respectively. in conclusion, the results showed that asam sunti methanol extract was more active in inhibiting the growth of Staphylococcus aureus bacteria than Escherichia coli bacteria and Candida albicans fungi.
ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT OF WHITE AND RED FLESH FROM GUAVA LEAF ( Psidium guajava. L) AGAINTS Staphylococcus aureus AND Escherichia coli Hilda Maysarah; Rika Apriani; Misrahanum Misrahanum
Jurnal Natural Volume 16, Number 1, March 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.007 KB) | DOI: 10.24815/jn.v16i1.4818

Abstract

An antibacterial activity test of ethanol extract of white and red flesh from guava leaf (Psidium guajava. L) against S.aureus and E.coli; using agar diffusion method was carried out in order to produce the extract. The extract was collected using maceration method. The concentration of extract was 7,8125; 6,1035; 5,00; 4,8828; 4,3944; and 3,90625 mg/mL. The results showed that both of extracts had antibacterial activities. Ethanol extract of white flesh of fruit guava leaf had (Minimum Inhibitory Concentration) MIC value at 5.000 mg/mL against S.aureus and 4.8828 mg/mL against E.coli. Whereas ethanol extract of red flesh of fruit guava leaf had MIC value at 4.3944 mg/mL against S.aureus and E.coli.  MIC value of ethanol extract of white flesh of fruit guava leaf is equal with MIC value of clindamicin concentration at 3.00 µg/mL against S.aureus, and 1.00 µg/mL against E.coli. The MIC value of red flesh of fruit guava leaf is equal to the MIC value of clindamicin concentration at 3.00 µg/mL against S.aureus, and 1.00 µg/mL against E.coli.
PENGARUH KOMBINASI EKSTRAK PETROLEUM ETER BAWANG PUTIH (Allium sativum Linn) DENGAN VITAMIN C TERHADAP AKTIVITAS Candida albicans Nurul Khaira; Misrahanum Misrahanum; Rinaldi Idroes; Muhammad Bahi; Khairan Khairan
Jurnal Natural Volume 16, Number 1, March 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.59 KB) | DOI: 10.24815/jn.v16i1.4725

Abstract

Garlic (Allium sativum) contains organosulfur compound that plays an important role as an antibacterial and antifungal activities. Ascorbic acid or vitamine C also has been show has a good activity as an antioxidant and as an antifungal. The aims of the research is to determine the effect of the combination of petroleum ether garlic extract with vitamin C against Candida albicans. Zone of inhibition testing done by Kirby-Bauer method. The results showed that the combination of petroleum ether garlic extract with vitamin C in concentration of 50% did not show an activity significantly. Meanwhile, the activity of petroleum ether garlic extract alone at concentration of 50 and 75% showed activities towards Candida albicans with a diameter of inhibition zone are 19.46 and 27.46 mm respectively. 
PENGARUH KOMBINASI EKSTRAK PETROLEUM ETER BAWANG PUTIH (Allium sativum Linn) DENGAN VITAMIN C TERHADAP AKTIVITAS Candida albicans Nurul Khaira; Misrahanum Misrahanum; Rinaldi Idroes; Muhammad Bahi; Khairan Khairan
Jurnal Natural Volume 16, Number 1, March 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v16i1.4725

Abstract

Garlic (Allium sativum) contains organosulfur compound that plays an important role as an antibacterial and antifungal activities. Ascorbic acid or vitamine C also has been show has a good activity as an antioxidant and as an antifungal. The aims of the research is to determine the effect of the combination of petroleum ether garlic extract with vitamin C against Candida albicans. Zone of inhibition testing done by Kirby-Bauer method. The results showed that the combination of petroleum ether garlic extract with vitamin C in concentration of 50% did not show an activity significantly. Meanwhile, the activity of petroleum ether garlic extract alone at concentration of 50 and 75% showed activities towards Candida albicans with a diameter of inhibition zone are 19.46 and 27.46 mm respectively. 
ANTIBACTERIAL ACTIVITY TEST OF ETHANOL EXTRACT OF WHITE AND RED FLESH FROM GUAVA LEAF ( Psidium guajava. L) AGAINTS Staphylococcus aureus AND Escherichia coli Hilda Maysarah; Rika Apriani; Misrahanum Misrahanum
Jurnal Natural Volume 16, Number 1, March 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v16i1.4818

Abstract

An antibacterial activity test of ethanol extract of white and red flesh from guava leaf (Psidium guajava. L) against S.aureus and E.coli; using agar diffusion method was carried out in order to produce the extract. The extract was collected using maceration method. The concentration of extract was 7,8125; 6,1035; 5,00; 4,8828; 4,3944; and 3,90625 mg/mL. The results showed that both of extracts had antibacterial activities. Ethanol extract of white flesh of fruit guava leaf had (Minimum Inhibitory Concentration) MIC value at 5.000 mg/mL against S.aureus and 4.8828 mg/mL against E.coli. Whereas ethanol extract of red flesh of fruit guava leaf had MIC value at 4.3944 mg/mL against S.aureus and E.coli.  MIC value of ethanol extract of white flesh of fruit guava leaf is equal with MIC value of clindamicin concentration at 3.00 µg/mL against S.aureus, and 1.00 µg/mL against E.coli. The MIC value of red flesh of fruit guava leaf is equal to the MIC value of clindamicin concentration at 3.00 µg/mL against S.aureus, and 1.00 µg/mL against E.coli.
Co-Authors Hilda Maysarah Hira Helwati Khairan Khairan Muhammad Bahi Nia Ayuningrum Nurul Khaira Ramadayani Fitri Rika Apriani Rinaldi Idroes Yulia Sari Ismail