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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) UNEJ e-Proceeding International Journal of Applied Biology Indonesian Journal of Chemistry JCES (Journal of Character Education Society) Jurnal Widya Medika Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Lanny Hartanti
Widya Mandala Catholic University Surabaya
Agriculture, Biological Sciences & Forestry Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Chemistry Education Energy Environmental Science Medicine & Pharmacology

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The Utilization of Nutraceuticals and Phytochemical Compounds to Inhibit The Interaction of Spike-protein SARS-CoV-2 Virus and ACE-2 Receptor for COVID-19 Therapy (Literature Review) Ferdinand, David; Hartanti, Lanny
International Journal of Applied Biology Vol. 7 No. 1 (2023): International Journal of Applied Biology
Publisher : Hasanuddin University

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Abstract

SARS-CoV-2 virus can cause Coronavirus disease 2019 (COVID-19). The interaction between spike protein and ACE2 receptor causes virus entry into the cells. The aim of this study was to review the utilization of nutraceutical and phytochemical agents to inhibit the interaction of spike protein envelope SARS-CoV-2 virus and ACE2 receptor. The data literature was retrieved from several databases such as Google scholar, Science direct, and PubMed. This study was conducted from September-October 2020. The review process was conducted based on PRISMA Guidelines.The results showed that nutraceuticals such as tuna peptides (EEAGGATAAQIEM), nisin, teicoplanin, zinc, propolis, Ganoderma lucidum, brown algae, and lectin have the potential to inhibit the interaction of spike protein SARS-CoV-2 virus and ACE2 receptor. Phytochemical compounds such as curcumin, luteolin, EGCG, hesperidin, resveratrol, saikosaponin, nicotianamine, procyanidin and the others also have the same. From this study, it can be concluded that nutraceuticals and phytochemical agents have potential benefits in COVID-19 treatment based on in silico study. However, we need further studies based on in vitro experiments and in vivo to ensure the effectivity of those nutraceutical agents.
PELATIHAN STEM UNTUK MENINGKATKAN MINAT PESERTA DIDIK SMA/SMK DALAM MEMILIH STUDI DAN KARIR BIDANG STEM Lestari, Tri; Wulani, Fenika; Lie, Anita; Hartanti, Lanny
JCES (Journal of Character Education Society) Vol 8, No 4 (2025): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jces.v8i4.35277

Abstract

Abstrak: Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan minat peserta didik SMA/SMK dalam melanjutkan studi dan karir di bidang Science, Technology, Engineering, dan Mathematics (STEM). Rendahnya minat siswa umumnya dipengaruhi keterbatasan pemahaman mengenai peran STEM dalam kehidupan sehari-hari serta kurangnya informasi terkait prospek studi dan karir. Untuk menjawab hal tersebut, tim pelaksana merancang program pelatihan berbasis partisipatif yang melibatkan siswa dari sekolah mitra. Metode pelatihan mencakup penyampaian materi interaktif, diskusi kelompok, praktik berbasis proyek, serta pemaparan peluang studi dan karir. Hasil kegiatan menunjukkan adanya peningkatan pemahaman siswa terhadap konsep STEM, tumbuhnya motivasi untuk mengeksplorasi bidang tersebut, serta meningkatnya minat memilih STEM sebagai arah studi dan karir. Guru pendamping juga memperoleh wawasan baru mengenai strategi pembelajaran STEM yang relevan diterapkan di sekolah. Dengan demikian, pelatihan ini tidak hanya meningkatkan literasi STEM, tetapi juga mendukung pengembangan pendidikan yang sesuai dengan kebutuhan abad 21.Abstract:  This community service program aimed to enhance the interest of high school and vocational school (SMA/SMK) students in pursuing further studies and careers in Science, Technology, Engineering, and Mathematics (STEM). Students’ lack of interest is often influenced by limited understanding of STEM’s role in daily life and insufficient information regarding study and career prospects. To address this, the team designed a participatory training program involving students from partner schools. The methods included interactive sessions, group discussions, project-based practices, and presentations on study and career opportunities. The results indicated improved student understanding of STEM concepts, increased motivation to explore the field, and stronger interest in considering STEM for future studies and careers. Teachers also gained new insights into STEM-based learning strategies applicable in classrooms. Thus, this training not only strengthened STEM literacy but also supported the development of education aligned with 21st-century demands.
Co-Authors Anita Lie Bernadette Dian Novita Caesilia Putri Utami Caesilia Putri Utami, Caesilia Putri Diga Albrian Setiadi Dyana Sarvasti Emi Sukarti Emi Sukarti, Emi Evelyn Ongkodjojo Fandy Susanto Fandy Susanto, Fandy Felix Kurniawan Adithia Fenika Wulani Ferdinand, David Fransiskus Reynaldy Henry Kurnia Setiawan Ivan Priyantono Iwan Satria Djuanda Lisa Soegianto Marcellino Rudyanto Martha Ervina Prihastuti, Angelina Ajeng Setiawan, Henry K. Shavna Arfi Rasyid Sianty Dewi Sumi WIjaya, Sumi Tri Lestari Yonas, Stefani Maureen Kasih