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UJI AKTIVITAS EKSTRAK BIJI SELASIH (Ocimum basilicum L.) DENGAN BEBERAPA PELARUT SEBAGAI ANTIPIRETIK PADA MENCIT (Mus musculus) Rahimah, Sitti; hendrarti, Wahyu; Ramlah, Sitti
Jurnal Ilmiah As-Syifaa Vol 7, No 2 (2015): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.534 KB) | DOI: 10.33096/jifa.v7i2.7

Abstract

Seeds basil (Ocimum basilicum L.) has been known to the publicand is widely used to treat a variety of diseases. One of its benefits as lowering fever but have not been proven scientifically. This study was to determine whether there is an antipyretic effecte basil seeds (Ocimum basilicum L.) and to determine the effectiveness of extracts of basil seeds by using some of the solvent is n-hexane, ethyl acetate and ethanol compared with paracetamol in mice (Mus musculus). This study was an experimental study using RAL. Experimental animals used were 15 mice, stages of research giving treatment af mice in each group who had fasted for 12 hours, measured rectal temperature (initial temperature), then injected with 1 ml peptone/tail subcutaneously. The data obtained were analyzed ANOVA followed BNJ test. Test antipyretic extract basil seeds (Ocimum basilicum) with some solvent, most effectively used as a solvent in the basil seeds that solvent ethyl acetate compared with solvent n-hexane and ethanol. The results oft his study showed that the extract of basil seeds antipyretic effect.
Evaluasi Penyimpanan Vaksin Pada Puskesmas Kabupaten Maros, Sulawesi Selatan paluseri, andi; Nurul Mufliha, Andi Naura; Hendrarti, Wahyu; Lukman Muslimin; Guntur, Muhammad
Media Farmasi Vol 20 No 1 (2024): Media Farmasi Edisi April 2024
Publisher : Jurusan Farmasi Poltekkes kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mf.v20i1.260

Abstract

Evaluation of Storing Vaccines at the Community Health Center in Maros Regency, South Sulawesi Vaccines are a biological preparation whose storage requires special attention because they are compassionate. Improper storage and distribution of vaccines will reduce the quality of the vaccine so that its effectiveness will also decrease or even not be effective at all. This study aims to determine the description of vaccine storage at the Community Health Center, Regency of Maros, South Sulawesi. This research is a qualitative descriptive study conducted at 14 Community Health Centers in April - June 2022. Data was collected using direct interview techniques with vaccine officials and direct observation at vaccine storage areas. The research results show that the storage system meets the minimum requirements, although several aspects still do not meet the criteria due to a lack of storage facilities. Vaccines include vaccine solvent and vaccine layout in a refrigerator equipped with a generator, not exposed to direct sunlight, and in a room with sufficient air circulation. There are vaccine vial monitors (VVM) in conditions A and B. Incoming and outgoing vaccines are reported and recorded on the stock card. Likewise, the COVID-19 vaccine is also stored under reasonable control. So, it can be concluded that the vaccine storage system at 14 community health centers in the district. Maros has fulfilled the requirements of the Ministry of Health, Republic of Indonesia, No. 12 in 2017. Vaksin merupakan salah satu sediaan biologi yang penyimpanannya membutuhkan perhatian khusus karena sangat sensitif. Penyimpanan dan pendistribusian vaksin yang tidak tepat akan menurunkan mutu vaksin sehingga efektivitasnya juga menurun bahkan tidak berkhasiat sama sekali. Penelitian ini bertujuan untuk mengetahui gambaran penyimpanan vaksin di Puskesmas Kab. Maros, Sulawesi Selatan. Penelitian ini bersifat deskriptif kualitatif yang dilakukan terhadap 14 puskesmas pada bulan April hingga Juni 2022. Data dikumpulkan dengan teknik wawancara langsung pada petugas penanggung jawab vaksin dan melakukan observasi langsung pada tempat penyimpanan vaksin. Hasil penelitian menunjukkan bahwa sistem penyimpanan sudah memenuhi syarat minimal walaupun masih ada beberapa aspek yang tidak terpenuhi kriteria karena kurangnya fasilitas penyimpanan. Vaksin termasuk pelarut vaksin dan tata letak vaksin di dalam refrigerator yang dilengkapi dengan generator (genset), tidak terkena sinar matahari langsung, dan ruangan yang memiliki sirkulasi udara yang cukup. Terdapat vaccine vial monitor (VVM) yang berada dalam kondisi A dan B. Vaksin yang masuk maupun keluar terlapor dan tercatat pada kartu stok. Begitu pula dengan vaksin covid-19 juga tersimpan dengan kontrol yang baik pula. Sehingga dapat disimpulkan sistem penyimpanan vaksin pada 14 Puskesmas di Kab. Maros telah memenuhi syarat PerMenKes No. 12 tahun 2017.
Edukasi Obat Tradisional dan Penyakit Diabetes Mellitus serta Hipertensi untuk Masyarakat Sidrap Abidin, Hamdayani Lance; Hapiwaty, Saldi; Ali, Alimuddin; Ningsih, Ririn Iriani; Tandiarrang, Lira; Hendrarti, Wahyu; Amin, Astuti
Yumary: Jurnal Pengabdian kepada Masyarakat Vol. 5 No. 4 (2025): Juni
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v5i4.3716

Abstract

Purpose: The purpose of the Arga Math program is to introduce and implement the “Plakat” (Rank Number Board) as an innovative teaching aid to enhance students’ mathematical understanding, specifically in exponentiation. This visual tool aims to foster student engagement, simplify abstract concepts, and support teachers in creating more interactive and effective learning environments. Methodology/approach: The socialization activity was conducted at MTS Sinoa using a service-learning approach focused on knowledge transfer. The session began with a brief presentation on the concept and function of Plakat Teaching Aid. This was followed by hands-on practice, where participants applied the tool to solve exponent-related problems. Feedback and perceptions were collected through a structured questionnaire completed by teachers and students after the activity. Results/findings: The results of the activity showed that the Plakat teaching aid helped both teachers and students better understand exponentiation. Students demonstrated increased enthusiasm and confidence in solving exponential problems, while teachers acknowledged the usefulness of the tool in delivering abstract content. Furthermore, the activity motivated educators to design similar instructional media that aligned with curriculum objectives and encouraged creativity in teaching mathematics. Conclusions: The Arga Math Plakat proved to be an effective visual learning aid, making abstract mathematical concepts more accessible. It positively affects learning outcomes and inspires both students and educators. Limitations: The activity had limited reach due to time constraints and the participation of only 13 eighth-grade students, with minimal involvement from other educators. Contribution: This initiative supports educational innovation and contributes to achieving SDG Goal 4: Quality Education.
Studi Penggunaan Obat dan Assessment Pengobatan pada Kasus Acute Kidney Injury dan Chronic Kidney Disease di Rumah Sakit Area Makassar Pawallangi, Andi Nur'ainun Reskia; Hendrarti, Wahyu; Oktaviany, Ni Wayan; Rante, Melty; Rotinsulu, Pinkan Fabiola; Hasmira, Hasmira
Majalah Farmaseutik Vol 21, No 3 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v21i3.106951

Abstract

Acute Kidney Injury (AKI) dan Gagal ginjal akut (GGK) merupakan kondisi dengan morbiditas dan mortalitas tinggi, yang membutuhkan evaluasi terapi yang tepat akibat perubahan farmakokinetik dan farmakodinamik pada pasien. Penelitian ini bertujuan mengevaluasi penggunaan dan kesesuaian pengobatan pasien AKI dan GGK di rumah sakit wilayah Makassar, dengan desain studi observasional deskriptif retrospektif menggunakan data rekam medis Januari–Desember 2022. Sebanyak 179 pasien diteliti, terdiri dari 37 pasien GGA dan 142 pasien AKI. Terapi AKI banyak melibatkan pemberian cairan (NaCl 0,9%, Ringer Laktat), diuretik, dan nutrisi seperti Nephrosteril. Sebanyak 17 pasien AKI menunjukkan perbaikan fungsi ginjal berdasarkan kadar kreatinin dan BUN. Pada pasien GGK, 90,84% menggunakan antihipertensi, terutama golongan calcium channel blocker, loop diuretik, dan ARB. Sebanyak 66 pasien mencapai target tekanan darah (<140/90 mmHg), sementara 43 lainnya tidak tercapai, kemungkinan karena faktor usia, obesitas, konsumsi alkohol, ketidakpatuhan minum obat, dan penurunan eGFR. Secara umum, terapi sudah sesuai dengan pedoman KDIGO dan JNC 8, namun evaluasi berkala dan pendekatan individual tetap dibutuhkan untuk hasil pengobatan yang optimal.