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Journal : Ulil Albab

Test Physical and Test Irritation Provision Cream Extract Aromatic Ginger ( Kaempferia Galanga L.) Suhendriyo, Suhendriyo; Dwi Astuti Handayani; Susilo Yulianto
ULIL ALBAB : Jurnal Ilmiah Multidisiplin Vol. 4 No. 4: Maret 2025
Publisher : CV. Ulil Albab Corp

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/jim.v4i4.8232

Abstract

Galangal rhizome is used in traditional medicine which has effectiveness as an anti-inflammatory and antitoxin. Galangal rhizome contains flavonoids, polyphenols, saponins, essential oils. The content of polyphenols in the form of ethylcinnamate can provide anti-inflammatory effects. The content of saponins, flavonoids, essential oils in galangal rhizome as a treatment for mycosis. The purpose of this study was to determine the results of physical tests and irritation tests of galangal extract cream preparations including organoleptic tests, homogeneity tests, spreadability tests, adhesion tests, pH tests, and irritation tests. The method used in this study was descriptive research, namely to observe the characteristics physical and irritation test results of the cream preparation of kencur rhizome extract. The results of This study is an organoleptic test with dark brown kencur rhizome preparation, semi-solid form, distinctive smell of kencur. The homogeneity test has a homogeneous cream result, the spreadability test result is 4.8 cm, the adhesion test result is 4.78 seconds, the pH test result is 5 and the irritation test of the kencur rhizome extract cream preparation when applied to the respondent's skin does not cause irritation. The results of the physical test that show results that are in accordance with the requirements include organoleptic tests, homogeneity tests, adhesion tests and pH tests. While in tests that do not comply with the requirements, namely the spreadability test, and the results of the irritation test show that the cream does not cause skin irritation reactions when applied.
Literature Study Of Chamomile ( Matricaria Chamomilla ) For Generalized Anxiety Disordered Suhendriyo, Suhendriyo; Fadila Anisa Perwito; Susilo Yulianto
ULIL ALBAB : Jurnal Ilmiah Multidisiplin Vol. 4 No. 4: Maret 2025
Publisher : CV. Ulil Albab Corp

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56799/jim.v4i4.8233

Abstract

Chamomile ( Matricaria chamomilla ) is one of the most widely used herbal medicines worldwide. Scientific evidence is needed to increase the use of chamomile in treating generalized anxiety disorder . This study aims to find out information from various scientific publications regarding the benefits of chamomile ( Matricaria chamomilla ) for generalized anxiety disorder . The sources of this study were obtained by collecting data from research results of journals indexed in Google Scholar, Science Direct and PubMed with publication years 2016-2021. Based on the search results, 341 journals with relevant titles were found in the Google Scholar database , 17 journals were found in Science Direct , and 5 journals were found in Pubmed . After being adjusted to the inclusion and exclusion criteria, 5 journals were selected for review. This study uses a literature study method. Based on the results of the literature that has been obtained, chamomile can be useful for reducing symptoms of generalized anxiety disorder with moderate to severe sufferers. The flavonoid content in chamomile has an anxiolytic effect that can reduce the regulation of the hypothalamic pituitary adrenal (HPA) axis. Apigenin, which is a flavonoid, specifically binds to the gamma-aminobutyric acid (GABA) receptor. The dosage forms used are chamomile extract capsules and chamomile hydroalcoholic extract .