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Effects of resistant starch of mixed tubers snacks on glucose metabolism, leptin, visceral fat and body mass index in type 2 diabetes mellitus (T2DM) Hidayat, Jenny; Sunarti, .; Mustofa, .; Sadewa, Ahmad Hamim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 51, No 1 (2019)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (259.686 KB) | DOI: 10.19106/JMedSci005101201906

Abstract

Resistant starch could lower blood glucose, decrease adipocyte in adipose tissue and affect satiety hormones such as leptin. Tubers and pumpkin have high content of resistant starch, but their effectiveness to type 2 diabetes mellitus (T2DM) has not been known clearly. This research was conducted to determine the effectiveness of snack consumption made from tubers and pumpkins to BMI, visceral fat, glucose and leptin levels in the blood of T2DM patients and the correlation between the variables. The research method was pre-post clinical trial. Sixteen T2DM patients were in treatment (RS) and control groups. Subjects in RS group were given snack twice daily for 4 weeks. After following wash out process for 4 weeks, the same subjects was continued as subjects’ control. Paired t-test and/or Wilcoxon-test was used to analyze the differences between values before and after treatment in the group and between groups. Pearson test was used to analyze the correlation of BMI, visceral fat, glucose and leptin level. The visceral fat was increased in RS group (p=0.04) after 4 weeks consuming snack but decrease in control group (p=0.04) without significant change of BMI. Leptin level was decreased (p=0.00) in RS group. Blood glucose significantly decreased (p=0.01) and leptin level increased slightly in control group. Comparing the RS and control group at the end of study, there were significantly different in the variation of visceral fat in the female groups (p=0.05) and leptin (p=0.05). Visceral fat correlated with BMI in the RS and control group. In conclusion, the mixed tubers and pumpkin snack decreased the leptin level but increased visceral fat.
Domain Stresor dan Hubungannya dengan Stres pada Mahasiswa Kedokteran di Masa Pandemi Covid-19 Prasetyo, Juan Alexsandra; Hidayat, Jenny; Surilena, Surilena; Widjaja, Nelly Tina
Majalah Kedokteran Indonesia Vol 72 No 6 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.6-2022-585

Abstract

Introduction: Medical students are a vulnerable population to develop mental health problems particularly during Covid-19 pandemic. During the learning process, a lot of stressors may cause stress. Method: A cross-sectional study was done on 796 medical students. Measuring instruments used were respondent characteristic questionnaire, MSSQ to measure stressor domains, and DASS-21 to measure stress. All clinical and preclinical students of School of Medicine and Health Sciences Atma Jaya Catholic University of Indonesia were included and those who refused to participate were excluded. Data analysis was done univariate, then bivariate with Spearman’s Rank correlation test. Result: Among respondents, 48.7% were stressed. Stressor domains reported to caused high stress were academic, teaching and learning, and group activities. Stressor domains reported to caused moderate stress were interpersonal and intrapersonal, social, and drive and desire. Overall, academic stressor was the most common finding. Stress was reported on 52.8% female and 40.2% male respondents. Stress was reported on 53.0% preclinical and 37.0% clinical students. There were positive and significant correlation between all stressor domains and stress (p less than 0.01, rs = 0.387 – 0.481). Conclusion: All stressor domains were significantly correlated to stress in medical students.