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All Journal Natural B Jurnal Penelitian Pendidikan IPA (JPPIPA) Sasambo Journal of Pharmacy
Siti Rahmatul Aini
University of Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Physics

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The Antibiofilm Activity of Jatropha curcas L.Latex on Staphylococcus aureus ATCC 25923 Rosmalinda Utami; Siti Rahmatul Aini; Dyke Gita Wirasisya
Natural B, Journal of Health and Environmental Sciences Vol 5, No 1 (2019)
Publisher : Natural B, Journal of Health and Environmental Sciences

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Abstract

Nosocomial infections worldwide shows high rates. One of the causes of nosocomial infections is Staphylococcus aureus. S. aureus as an infectious pathogen is known to form biofilms that often cause failure of antibiotic therapy. Jatropha is one of the plants used by the community in treating various diseases, including infections. The purpose of this study was to determine the jatropha latex antibiofilm activity on S. aureus by microdilution method with crystal violet staining. The results showed that jatropha latex extract had antibiofilm activity, with biofilm inhibition percentages of 150% at concentrations of 0.625 mg/mL, while percent degradation was 189% at concentrations of 5 mg/mL. Jatropha latex extract had biofilm inhibition activity at extract concentrations of 0.625 mg/mL and biofilm degradation at extract concentration of 5 mg/mL. The result of this study can be used as topical drugs for infectious wounds.
Evaluasi kesesuaian peresepan obat terhadap formularium nasional di Rumah Sakit Umum Daerah Sumbawa tahun 2021 Titania Nabilah; Ni Made Amelia Ratnata Dewi; Siti Rahmatul Aini
Sasambo Journal of Pharmacy Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i1.204

Abstract

Hospitals should follow the National Formulary when prescribing medications. In accordance with the National Formulary, the percentage of drug prescriptions in a hospital must be at least 80%, according to the health service quality indicator standard number 30 of 2022 about hospital prescriptions. One of West Nusa Tenggara Province's class C hospitals, the Sumbawa Regional General Hospital treats patients with National Health Insurance (NHI), whose population is steadily growing. The purpose of this study is to assess the Sumbawa Regional General Hospital's suitability to prescribe medications in 2021 in accordance with the National Formulary. Retrospective data gathering is used in the observational research design. Based on inclusion and exclusion criteria, the research sample consisted of all prescription sheets for both inpatients and outpatients at the Sumbawa Hospital from January to December 2021. Prescription forms, drug content, dosage strengths, and dosing forms are all indicators of eligibility for prescribing. By comparing the number of prescriptions for drugs written according to the National Formulary with the total number of prescriptions, the suitability percentage was computed. The National Formulary states that 87.65% of medication items are suitable for prescription. According to the National Formulary, 87.65% of medicine items were suitable, and 66.2% of prescription sheets were as well. The Sumbawa Hospital's prescriptions are not 100% in accordance with the National Formulary, yet based on drug items have exceeded the standard indicators of drug prescriptions on hospital (more than 80%).
The Effect of Propolis Trigona sp. Water Extract from North Lombok on Blood Sugar Levels in Vivo Muhammad Naufal Farras Ananta; Imasayu Nuralyza; Ani Fatin Humaira; Salwa Sausan; Lalu Husnul Hidayat; Raisya Hasina; Iman Surya Pratama; Yayuk Andayani; Siti Rahmatul Aini
Jurnal Penelitian Pendidikan IPA Vol 10 No 8 (2024): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i8.7459

Abstract

Propolis has been touted for its ability to regulate blood sugar levels in diabetes, but the effectiveness can vary depending on the region. A study was conducted to investigate the effect of propolis Trigona sp. water extract on blood sugar levels in vivo. The mice were divided into three groups, with four mice in each group. The positive control group received a 5 mg/kgBW glibenclamide suspension, the negative control group was given a 0.25% CMC-Na suspension, and the treatment group was administered with water extract of propolis at a dose of 300 mg/kgBW. All groups were induced with a 20% D-glucose solution intraperitoneally, and blood sugar levels were measured at 15, 30, 60, 90, and 120 minutes via the tail vein. The blood sugar data was analyzed and presented descriptively. The Mann-Whitney statistical analysis was used to determine the results, revealing that the water extract of propolis at 300 mg/kgBW did not have a significant effect on reducing blood sugar levels in animals induced by a 20% D-glucose solution, with a significance value (p < 0.05).
Co-Authors Ani Fatin Humaira Dyke Gita Wirasisya Iman Surya Pratama Imasayu Nuralyza Lalu Husnul Hidayat Muhammad Naufal Farras Ananta Ni Made Amelia Ratnata Dewi Raisya Hasina Rosmalinda Utami Salwa Sausan Titania Nabilah Yayuk Andayani