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<![CDATA[APLIKASI ANALISIS KIMIA KUANTITATIF UNTUK PEMANTAUAN KADAR OBAT (THEURAPETIC DRUGS MONITORING) ]]>
<![CDATA[Dewi, Ni Made Amelia Ratnata]]>
<![CDATA[ AMINA Vol 1 No 1 (2019): April 2019 ]]>
Publisher : <![CDATA[Department of Chemistry, Faculty of Science and Technology, UIN Ar-Raniry ]]>
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DOI: 10.22373/amina.v1i1.8
<![CDATA[Theurapetic drugs monitoring (TDM) is used to adjust individual drug therapy. TDM purpose is to maximize the therapeutic effect and reduce the side or toxic effects of the drug. In general, TDM includes sample preparation, conducting drug analysis and interpreting the concentration of the drug. The development of analytical techniques resulted in the determination of pharmacokinetic characters by measuring drug concentrations in the blood more easily. Drug analysis can be done by spectrophotometric, chromatographic or immunoassay methods. Immunoassay could provide fast results and easy to use, but this method cannot distinguish between drugs that have similar structures. In addition, immunoassays are not available for all drugs monitored in clinical laboratories, so chromatographic methods such as GC, HPLC, GC/MS, and HPLC / MS can still be applied to TDM.]]>
<![CDATA[Uji Validitas dan Reliabilitas Kuesioner Penggunaan dan Penyimpanan Antibiotika di Kecamatan Ampenan ]]>
<![CDATA[Meivira, Audra]]>;
<![CDATA[Ratnata Dewi, Ni Made Amelia]]>;
<![CDATA[Puspitasari, Candra Eka]]>
<![CDATA[ Archives Pharmacia Vol 4, No 1 (2022): ARCHIVES PHARMACIA ]]>
Publisher : <![CDATA[Lembaga Penerbitan Universitas Esa Unggul ]]>
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<![CDATA[Uji validitas dan reliabilitas kuesioner penting dilakukan sebelum memulai sebuah penelitian. Uji ini dilakukan untuk mengetahui kelayakan sebuah kuesioner yang digunakan sebagai instrumen dalam penelitian. Penelitian ini dilakukan untuk mengetahui validitas dan reliabilitas kuesioner yang akan digunakan untuk mengukur tingkat pengetahuan masyarakat Ampenan tentang penggunaan dan penyimpanan antibiotik. Desain penelitian yang digunakan yaitu cross sectional dengan cara melakukan survey melalui media kuesioner. Instrumen penelitian yang digunakan berupa kuesioner tertutup dengan jumlah 29 pertanyaan. Pengambilan sampel uji validitas dan reliabilitas dilakukan menggunakan metode cluster sampling. Sampel uji sebanyak 30 KK (pada 30 Rukun Tetangga (RT)) di Kecamatan Ampenan. Setelah memperoleh data, kemudian diolah dan dianalisis menggunakan korelasi Product Moment. Hasil yang diperoleh dari uji validitas dan reliabilitas yaitu terdapat 22 pertanyaan valid dengan nilai reliabilitas sebesar 0,902.]]>
<![CDATA[Edukasi Pentingnya Pemberian Vaksin Covid-19 Di Kota Mataram ]]>
<![CDATA[Ni Made Amelia Ratnata Dewi]]>;
<![CDATA[Siti Rahmatul Aini]]>;
<![CDATA[Iman Surya Pratama]]>;
<![CDATA[Candra Eka Puspitasari]]>;
<![CDATA[Raisya Hasina]]>
<![CDATA[ Jurnal Pengabdian Masyarakat Sains Indonesia Vol. 3 No. 2 (2021) ]]>
Publisher : <![CDATA[Universitas Mataram ]]>
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DOI: 10.29303/jpmsi.v3i2.143
<![CDATA[Salah satu harapan terbesar untuk menghentikan pandemi coronavirus 2019 (COVID-19) adalah vaksin. Badan Pengawas Obat dan Makanan telah mengeluarkan persetujuan penggunaan darurat Emergency Use Authorization (EUA) untuk penggunaan vaksin COVID-19 dengan mempertimbangkan keadaan emergensi dan bukti terbatas kemanfaatan dan keamanan vaksin tersebut. Pemberian vaksin penuh COVID-19 hingga tanggal 25 Februari 2021 baru mencapai kepada 853.754 orang atau sekitar 0,31% dari jumlah seluruh populasi penduduk Indonesia. Pengabdian ini bertujuan untuk memberikan edukasi kepada masyarakat terkait pentingnya pemberian vaksin COVID-19. Edukasi dilakukan dengan mengadakan webinar menggunakan aplikasi web conference dengan mengundang pembicara ahli di bidang mikrobiologi, farmasi dan kesehatan anak terkait manfaat dan keamanan pemberian vaksin. Pengetahuan masyarakat terkait pentingnya vaksin sebelum dan sesudah edukasi diukur melalui pretest dan post test. Kegiatan edukasi berjudul “Mitos dan Fakta tentang Vaksin COVID19 telah dilakukan dengan metode webinar menggunakan aplikasi zoom. Kegiatan ini diikuti oleh 110 orang. Kegiatan berjalan dengan lancar sesuai dengan rencana. Terdapat peningkatan nilai rerata pre-test dari 77 menjadi 88 pada saat post-test dengan nilai maksimum adalah 100. Kegiatan terlaksana dengan baik, terlihat dari peningkatan nilai rerata pre-test dan post-test.]]>
<![CDATA[Pola Pemberian Obat Antihipertensi pada Pasien Geriatri di Instalasi Rawat Inap RSUD Provinsi NTB Tahun 2017 ]]>
<![CDATA[Mia Cahya Lestari]]>;
<![CDATA[Raisya Hasina]]>;
<![CDATA[Ni Made Amelia Ratnata Dewi]]>
<![CDATA[ Jurnal Pharmascience Vol 8, No 1 (2021): Jurnal Pharmascience ]]>
Publisher : <![CDATA[Program Studi Farmasi FMIPA Universitas Lambung Mangkurat ]]>
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DOI: 10.20527/jps.v8i1.9444
<![CDATA[Hipertensi merupakan salah satu penyakit yang diderita oleh pasien usia lanjut (geriatri) dengan persentase kejadian terbanyak yaitu sebesar 57,6%. Hipertensi pada pasien geriatri dapat disebabkan karena penurunan fungsi organ, sehingga akan lebih rentan terkena penyakit. Penelitian ini bertujuan untuk melihat gambaran pola pemberian antihipertensi serta kesesuaian pengobatan hipertensi pada pasien geriatri di Instalasi Rawat Inap RSUD Provinsi NTB tahun 2017. Penelitian dilakukan secara deskriptif dengan metode pendekatan observasional secara retrospektif terhadap pasien hipertensi di Instalasi Rawat Inap RSUD Provinsi NTB. Pengambilan data dilakukan dengan metode Total sampling terhadap 97 pasien geriatri. Data yang diperoleh dari bagian rekam medik dan resep ditabulasi dengan software microsoft excel. Setelah dilakukan penelitian didapatkan bahwa terapi untuk hipertensi didominasi oleh obat dengan dua kombinasi yaitu amlodipin dan valsartan (88%). Obat tunggal didominasi oleh amlodipin (75%). Kesesuaian peresepan dilihat dari dosis dan frekuensi terapi antihipertensi telah sesuai 100% dengan pedoman pengobatan, namun jenis obat yang digunakan hanya mencapai 99% dilihat dari pemberian kombinasi 3 antihipertensi dengan kombinasi golongan Angiotensin Converting Enzyme Inhibitor (captopril) dan golongan Angiotensin Receptor Blocker (candesartan) yang menimbulkan potensi interaksi mayor dan efek samping (1%). Kata Kunci: Hipertensi, Geriatri, Pola Pemberian Obat. Hypertension is a disease that affects geriatric with the highest percentage of incidence was 57.6%. Hypertension in geriatric patients can be caused by decreased organ function, so they are more susceptible to disease. The purpose of this study was to describe the pattern of antihypertensive drugs also the appropriateness of hypertension therapy in geriatric patients. This study was held in the inpatient Installation of the NTB Provincial Hospital in 2017. The design of this study was descriptive by collecting data retrospectively on 97 geriatric patients. The data obtained from the medical record and prescription sections were processed using Microsoft Excel software. The result showed that the therapy for hypertension was dominated by combination drugs which consist of amlodipine and valsartan (88%) and single drugs were dominated by amlodipine (75%). The appropriateness of prescription was seen from the dosage and frequency in the main therapy (hypertension) was 100% according to the treatment guidelines, but the type of drug that used was only 99% which seen from the giving combination of 3 antihypertensive drugs of Angiotensin-Converting Enzyme Inhibitor (captopril) and Angiotensin Receptor Blocker (candesartan) groups which caused interactions major and side effects (1%).]]>
<![CDATA[Interaksi Obat Antara Klopidogrel dan Proton Pump Inhibitor (PPI) ]]>
<![CDATA[Ni Made Amelia Ratnata Dewi]]>
<![CDATA[ Sasambo Journal of Pharmacy Vol. 1 No. 1 (2020): April ]]>
Publisher : <![CDATA[Universitas Mataram ]]>
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DOI: 10.29303/sjp.v1i1.12
<![CDATA[Abstrak: Pemberian Proton Pump Inhibitor (PPI) dapat menurunkan terjadinya kejadian perdarahan gastrointestinal berulang pada pasien yang mendapatkan dual therapy antiplatelet yaitu klopidogrel dan aspirin. Klopidogrel diaktivasi melalui proses metabolisme oleh enzim CYP2C19 sedangkan obat golongan PPI dimetabolisme dan menghambat enzim CYP2C19. Studi farmakodinamik menunjukkan adanya efek PPI terutama omeprazole terhadap metabolisme klopidogrel yang dapat mengakibatkan penurunan efek dari inhibisi platelet. Beberapa studi klinik mendapatkan bahwa tidak terdapat kejadian yang dapat menyebabkan permasalahan pada jantung (cardiovascular event) jika kedua obat diberikan secara bersamaan. Kemaknaan klinis dari interaksi obat dari klopidogrel dan PPI belum diketahui secara jelas sehingga untuk keamanan direkomendasikan untuk membatasi penggunaan PPI terutama omeprazole. Pilihan lain adalah dengan mengganti PPI dengan H2 blocker ataupun menggunakan golongan PPI yang tidak banyak dimetabolisme oleh enzim CYP2C19 seperti pantoprazole.]]>
<![CDATA[Pola peresepan antibiotik pada pasien infeksi saluran kemih di instalasi rawat jalan RSUD Provinsi NTB tahun 2017 ]]>
<![CDATA[Dwi Herlina]]>;
<![CDATA[Raisya Hasina]]>;
<![CDATA[Ni Made Amelia Ratnata Dewi]]>
<![CDATA[ Sasambo Journal of Pharmacy Vol. 2 No. 1 (2021): April ]]>
Publisher : <![CDATA[Universitas Mataram ]]>
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DOI: 10.29303/sjp.v2i1.26
<![CDATA[Urinary tract infection (UTI) is an infection due to the proliferation of microorganisms in the urinary tract. UTI is usually occur in the community at various ages. In 2014, Indonesian Ministry of Health showed that the number of people with UTIs reached 90-100 cases per 100,000 population per year. Antibiotics are the main therapy used in treating urinary tract infections. The purpose of this study was to determine the pattern of antibiotic prescribing in UTI patients and determine the suitability of therapy with guidelines for UTI at the Installation of NTB Provincial Hospital in 2017. The design of this study was descriptive by collecting data retrospectively. The study was conducted on 105 UTI patients at the Installation Hospital of NTB Province in 2017, then the data obtained from the medical record and prescription sections were processed using Microsoft Excel software. The results showed that therapy for UTI patients was antibiotics with the most use of ciprofloxacin (45.71%), then cefixime (40%), urinter (pipemidic acid) (11.43%), levofloxacin (1.90%), cefadroxil (0.95 %). Based on these results, the suitability of prescription was seen from the type of drug and the dosage in the main therapy (antibiotics) was 100% according to the treatment guidelines, but the frequency and duration of administration only reached 99.05% and 88.6%.]]>
<![CDATA[Evaluasi pola penggunaan obat dispepsia berdasarkan indikator WHO (World Health Organization) pada pasien rawat jalan Puskesmas Karang Taliwang tahun 2019 ]]>
<![CDATA[Helen Nabila]]>;
<![CDATA[Ni Made Amelia Ratnata Dewi]]>;
<![CDATA[Ima Arum Lestarini]]>
<![CDATA[ Sasambo Journal of Pharmacy Vol. 3 No. 1 (2022): April ]]>
Publisher : <![CDATA[Universitas Mataram ]]>
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DOI: 10.29303/sjp.v3i1.139
<![CDATA[Dyspepsia is a collection of several clinical symptoms consisting of pain in the pit of the stomach, flatulence, early satiety, nausea, and vomiting. The incidence of dyspepsia at the Karang Taliwang Public Health Center until 2019 was quite high. Evaluation of drug use at the Puskesmas has never been carried out, so it is necessary to know the pattern of use of dyspepsia drugs at the Karang Taliwang Public Health Center. This review aimed to determine the pattern of dyspepsia drug use in outpatient dyspepsia at Karang Taliwang Public Health Center using prescribing indicators developed by the World Health Organization. This study is a descriptive study of retrospective drug use. Sampling using a consecutive sampling method. Prescription data and medical records were collected through observation sheets. The results of the study on drug use patterns were the average number of drug items per sheet of 2.55 prescription; the percentage of drugs prescribed with generic names was 99,37%; the percentage of prescription drugs with antibiotics was 1.61%; the percentage of prescription drugs with injection preparations was 0%; and the percentage of drugs prescribed according to the Formularium was 96.84%.]]>
<![CDATA[Uji validitas dan reliabilitas instrumen kuesioner gambaran penggunaan obat nyeri haid secara mandiri pada mahasiswi Fakultas Kedokteran Universitas Mataram ]]>
<![CDATA[Rosa Ninty Oktamadila]]>;
<![CDATA[Iman Surya Pratama]]>;
<![CDATA[Ni Made Amelia Ratnata Dewi]]>
<![CDATA[ Sasambo Journal of Pharmacy Vol. 3 No. 1 (2022): April ]]>
Publisher : <![CDATA[Universitas Mataram ]]>
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DOI: 10.29303/sjp.v3i1.154
<![CDATA[Self-medication often becomes a choice for various complaints, one of which is menstrual pain. Regarding the description of the use of menstrual pain medication independently, it is still limited. The use of a questionnaire as a research instrument that has been tested for validity and reliability is very necessary. Therefore, this study aims to develop and test the validity and reliability of the description of the independent use of menstrual pain medication in female students. This research is a descriptive survey type with a cross-sectional design. The validity test was carried out using a qualitative and quantitative professional assessment method, namely by using the Content Validity Ratio (CVR). An advance validity test was conducted by 5 experts and 40 respondents. The reliability test was carried out with 40 respondents and used the Chronbach Alpha value. The results of the validity test obtained 28 questions with a CVR value of 1. Facial validity was declared valid after one repair. The reliability of the test obtained Cronbach's Alpha coefficient value of 0.934. Based on the validity and reliability test of the questionnaire, it was declared valid and reliable so that all questions could be used as an instrument to find out the description of the use of menstrual pain medication independently.]]>
<![CDATA[Sosialisasi Pencegahan Penyakit Infeksi Kecacingan Di Wilayah Mataram ]]>
<![CDATA[Ni Made Amelia Ratnata Dewi]]>;
<![CDATA[Candra Eka Puspitasari]]>;
<![CDATA[Nisa Isneni Hanifa]]>
<![CDATA[ INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 1 (2020): April ]]>
Publisher : <![CDATA[Universitas Mataram ]]>
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DOI: 10.29303/indra.v1i1.18
<![CDATA[Abstract: Helminthiasis is an infection that often attacks children and could result in decreased health, nutrition, intelligence and productivity of the patient. The purpose of this community service activity is to organize a socialization that can improve the understanding of helminthiasis dangers and how to prevent it. The socialization method that used are presentation of the material by the speakers, discussions session and brochures distribution for the audition. The socialization was held in the South Batu Ringgit area. As many as 30 residents participated in this activity. The socialization went well and has produced the expected outcomes. Pre and post assesment to evaluate resident knowledge about helminthiasis were done by written multiple choice quiz. The difference between the pre-test and post-test score was carried out using the Wilcoxon test. Wilcoxon test results showed that there were significant differences between the pre-test and post-test with p values= 0.03 Keywords: infection, helminthiasis, socialization]]>
<![CDATA[Pengembangan media edukasi diabetes mellitus untuk tenaga kefarmasian di puskesmas wilayah Mataram ]]>
<![CDATA[Ni Made Amelia Ratnata Dewi]]>;
<![CDATA[Iman Surya Pratama]]>;
<![CDATA[Candra Dwipayana Hamdin]]>
<![CDATA[ INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 1 (2021): April ]]>
Publisher : <![CDATA[Universitas Mataram ]]>
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DOI: 10.29303/indra.v2i1.89
<![CDATA[Adherence in using drugs is one of the factors that determine the success of therapy, especially for chronic diseases such as diabetes mellitus. Efforts that can be made by health workers in increasing adherence to diabetes mellitus sufferers in undergoing treatment are to pay attention to providing information and education to patients. The purpose of this community service activity is to develop educational media for type II diabetes mellitus for pharmaceutical workers in the Mataram regional health center. Making diabetes education media is done by making a pocket book which aims to make it easier for health workers to carry out counseling related to diabetes mellitus and its treatment.]]>
