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All Journal The Journal of Pure and Applied Chemistry Research
Sasangka Prasetyawan
Chemistry Department, Brawijaya University
Chemical Engineering, Chemistry & Bioengineering Chemistry Materials Science & Nanotechnology Medicine & Pharmacology

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Biosorption of Lead(II) using Trichoderma viride in the Aqueous Solution Rensani Taloin; Anna Safitri; Sasangka Prasetyawan; Budi Kamulyan; Ulfa Andayani
The Journal of Pure and Applied Chemistry Research Vol 7, No 1 (2018): Edition January-April 2018
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (907.361 KB) | DOI: 10.21776/ub.jpacr.2018.007.01.399

Abstract

Lead(II) is considered as the main cause of pollutant that is toxic, corrosive, and irritant. One method that can be applied for reducing Pb(II) in the environment is by using microorganisms. In this work, the study of biosorption of Pb(II) in the water samples was conducted using Trichoderma viride. The research is focused on determination of optimum conditions including pH, biosorption time, and initial concentration of Pb(II) used. The profiles in functional groups contained in the T. viride have been monitored using FT-IR spectrophotometry. Results showed that the maximum biosorption of Pb(II) achieved at pH 4.5, with equilibrium of contact time of 20 h, optimum concentration of 50 mg/L, and adsorption capacity of 85 mg/1x106 T. viride colonies. The FTIR results indicated that biosorption process changed the functional groups in the T. viride. These have shown in the absorption bands at ~3200 cm-1, ~2850 cm-1, ~2260 cm-1, ~1650 cm-1,  ~1450 cm-1, 1180 cm-1, and in the finger printing regions. The biosorption mechanism was proposed through the adsorption process between positively charged metal ions and the negative charge on the functional groups, such as -COO-, -OPO32-, and –NH2-, on the cell surface.
Methanol Extracts Potential of Mas Ngur Shells (Atactodea striata) against Protease Profile and Description of Histopathology of Jejunum Rats Exposed by Indomethacin Vivi Shofia; Celcius Waranmasalembun; Sasangka Prasetyawan; Aulanni'am Aulanni'am
The Journal of Pure and Applied Chemistry Research Vol 4, No 2 (2015)
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (865.907 KB) | DOI: 10.21776/ub.jpacr.2015.004.02.218

Abstract

Inflammatory Bowel Disease (IBD) is a multi-factorial disorder caused by genetic factors, environmental and immune response. One of the causes of IBD is a side effect of non-steroidal of anti-inflammatory drugs (NSAIDs). Indomethacin is an NSAID that activates macrophages and triggers increasing of protease activity. Mas Ngur shells (Atactodea striata) contains an antioxidant that inhibits the protease activity. This research used rats (Rattus norvegicus) induced by Indomethacin and treated with methanol extract of Mas Ngur shells (A. striata) at doses of 100 and 400 mg/kg of body weight (BW). Therapy potency of the Mas Ngur shells methanol extracts were identified by measuring protease activity and observed the Jejenum histopathology. Statistical analysis showed that the Mas Ngur shells therapy showed significant differences (p <0.05) by decreasing of protease activity and improve jejunum histopathology of IBD induced rats
Co-Authors Aulanni&#039;am Aulanni&#039;am Budi Kamulyan Celcius Waranmasalembun Rensani Taloin Safitri, Anna Ulfa Andayani Vivi Shofia