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All Journal Indonesian Journal of Pharmaceutical Science and Technology KIDDO: Jurnal pendidikan Islam Anak Usia Dini
Tiara Julianti
Unknown Affiliation
Computer Science & IT Education Medicine & Pharmacology

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Tyrosinase Inhibition from Green Tea (Camellia sinensis (L.) Kuntze) gel Hanifah Rahmi; Supandi Supandi; Naniek Setiadi Radjab; Tiara Julianti
Indonesian Journal of Pharmaceutical Science and Technology Vol 8, No 2 (2021)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v8i2.27145

Abstract

Green tea (Camellia sinensis (L.) Kuntze) leaf has polyphenol substance that able to inhibit tyrosinase enzyme. Tyrosinase enzyme is one of the essential components that can be initiated melanin formation on the skin (melanogenesis). The natural inhibitory enzyme can be utilized in cosmetics and medicinal industries as depigmentation agent. Green tea leaf was formulated in the dosage form of a gel with carbomer 934 as a gelling agent. This study aimed to determine the optimum concentration of carbomer 934 on green tea leaf extract gel that has an inhibitory tyrosinase activity. This research used three carbomer 934 concentration, there was 0.5%, 0.75%, and 1% respectively. Which every formula was evaluated during six weeks involve organoleptic, homogeneity, viscosity, pH, centrifuge, and freeze-thaw test (during six cycles). The optimum formula was evaluated tyrosinase activity used a spectrophotometer-vis. The results showed that the great concentration of carbomer 934 was contained on the first formula, which has not phase separation and 49.62 ppm of IC50 value. This research showed that green tea leaf extract gel with 0,5% carbomer 934 prevented tyrosinase activity. Keywords: Carbomer 934, gel, green tea leaf extract, inhibitory of tyrosinase
Pengaruh Media Colour Corrugated Paper (Kokoru) Terhadap Kemampuan Kreativitas Anak Usia Dini Tiara Julianti; Akbari; Alrefi; Rini Susanti
Kiddo: Jurnal Pendidikan Islam Anak Usia Dini Vol. 5 No. 2 (2024)
Publisher : Institut Agama Islam Negeri Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19105/kiddo.v5i2.13325

Abstract

This research aims to determine the effect of colored corrugated paper (kokoru) media on the creative abilities of group B children at KB Aisyiyah 5 Baturaja. The type of research used was pre-experiment with a one-shot case study design. The sampling technique used purposive sampling, namely class B with a total of 20 children consisting of 12 boys and 8 girls. The data collection technique used will then be analyzed using a one-sample t-test. The results obtained were t-value of 5.74 with a significance of 0.05 and the degrees of freedom were 19 so that a t-table of 1.729 was obtained. So the t-value of 5.74 is greater than t-table of 1.729. So it can be concluded that there is an influence of Color Corrugated Paper (Kokoru) Media on the Creativity Abilities of Group B Children at KB Aisyiyah 5 Baturaja.
Co-Authors Akbari Alrefi Hanifah Rahmi Naniek Setiadi Radjab Rini Susanti Supandi