Dewi Agustina
Department of Oral Medicine, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta

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The relationship between salivary secretion and taste sensitivity level in the elderly Fimma Naritasari; Dewi Agustina; Supriatno Supriatno
Majalah Kedokteran Gigi Indonesia Vol 4, No 3 (2018): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (369.674 KB) | DOI: 10.22146/majkedgiind.36903

Abstract

The increasing population of the elderly has an impact on health problems, including an increase of oral problems. One of the common oral problems is dry mouth that possibly disrupts gustatory function. The aim of this study was to investigate the relationship between salivary secretion and taste sensitivity level in the elderly. This study was a cross sectional study for the elderly population of Daerah Istimewa Yogyakarta/The Special Region of Yogyakarta (DIY) Province, Indonesia. This study consisted of interview, clinical examination, measurement of salivary secretion (sialometry) and taste sensitivity level using chemical gustometry method. Salivary secretion data were described in ml/ min. The measurement of taste sensitivity level was performed using 4 different substances: sweet (sucrose), salty (NaCl), sour (citric acid) and bitter (quinidine sulphate) with 4 different concentrations for each flavor. Four score was given if the respondent recognized the lowest concentration of the substance and 0 score was provided when all concentrations were failed to be tasted. Total score for test sensitivity level was scaled from 0 to 16. Salivary secretion data and taste sensitivity level data were analyzed by Spearman correlation test to determine the correlation between both variables. There were 103 subjects (70 women and 33 men) with the age mean of 65.61 years old, participating in this study. The mean of the sweet taste level was 2.81, 3.32 for salty taste, 3.69 for sour taste and 2.98 for bitter taste. Total taste sensitivity level mean was 12.80 out of 16. The measurements of unstimulated whole saliva showed a mean value of 0.170 ml/min with the majority of subjects having normal salivary flow. The Spearman correlation test results showed r= -0.078 with p >0.05 that indicated no correlation. We concluded that there was no relationship between salivary secretion and taste sensitivity level in the elderly.
The effect of papaya leaf extract (Carica papaya L) on healing process of buccal traumatic ulcer in wistar rats Afryla Femilian; Dewi Agustina; Goeno Subagyo
Majalah Kedokteran Gigi Indonesia Vol 5, No 1 (2019): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (611.789 KB) | DOI: 10.22146/majkedgiind.37026

Abstract

Indonesians have been using herbal medicines for a long time to cure some illnesses. Carica papaya L is an example of an herb that contains papain enzymes, saponins, lysozymes, lipases, flavonoids, polyphenols and vitamin C. These  ingredients are believed to be beneficial for the wound healing process. The purpose of this study was to determine the effect of topical application of ethanolic extract of Carica papaya L to the healing process of rat mouth ulcer. Subjects were 32 Wistar rats divided into 2 groups (control group and treatment group), each group containing 16 rats. All subjects were made to suffer from ulcers using glacial acetyl acid applied for 40 seconds in the buccal mucosa. Treatment group was treated with papaya leaf ethanolic extract on ulcers twice a day using microbrush, while the ulcer in the control group was not treated with the extract. The ulcerated tissue was biopsied and stained with H&E. Observations were performed on the day 0, 3rd, 7th and 12th on HE slides. Data were observed by looking at three indicators of wound healing i.e. macrophage, angiogenesis and re-epithelisation. Number of macrophages and angiogenesis were analyzed using two-way ANOVA. Data of epithelial thickness were analyzed using Kruskal-Wallis test. The post hoc test in the treatment group and the control group on day 0 showed results of p = 1.00. On day 3, day 7 and day 12, the result of p was <0.05. In the treatment group on day 0 compared to the treatment group on the 3rd, 7th, 12th day, the results were p<0.05. In the treatment group on the 3rd day compared to the 7th and 12th days the results were p>0.05. The treatment group on the 7 day compared to the treatment group on the 12 day had p>0.05. In the control group, on day 0 compared to day 3, the results of p>0.05, while the control group day 0 with day 7, 12 had a result of p<0.05. The control group on the 3rd day was compared with the 7th day. The 12th also had a result of p<0.05. The comparison between the 7 day control groups showed p of >0.05. These data suggest that the papaya leaf ethanolic extract could accelerate the healing of oral ulcer on the buccal mucosa of wistar rats.
Oral health-related quality of life in type 2 diabetic patients of Yogyakarta General Hospital Dewi Agustina; Nunuk Purwanti; Lisdrianto Hanindriyo; Fimma Naritasari
Majalah Kedokteran Gigi Indonesia Vol 7, No 1 (2021): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.43693

Abstract

Yogyakarta is a province in Indonesia with the highest prevalence (2.4%) of Diabetes Mellitus (DM). Around 90% of diabetic patients suffer from type 2 DM. Oral manifestations of DM may disturb oral functions which in turn influence oral health - related quality of life (OHRQo)L. This study aimed to evaluate the OHRQoL of type 2 DM outpatients in Yogyakarta General Hospital. The study subjects comprised 50 male outpatients and 32 female outpatients with type 2 DM (40-81 years old). Geriatric Oral Health Assessment Index (GOHAI) and Xerostomia Inventory were used to assess OHRQoL and xerostomia status, respectively. Intraoral examinations comprising periodontal tissue, oral hygiene (OH), coated tongue, and present teeth were performed. There were 49 (59.76%) subjects with low and 33 (40.24%) subjects with high score of GOHAI; 78 (95.12%) with and 4 (4.88%) without periodontal tissue defect; 79 (96.34%) with poor and 3 (3.66%) good OH; 17 (20.73%) with coated tongue >50% and 65 (79.27%) with coated tongue ≤50%; 34 (41.46%) with present teeth <20 and 48 (58.54%) with present teeth ≥20; and 39 (47.56%) with xerostomia and 43 (52.44%) with normal status. Only ‘present teeth’ had a significant contribution to the proportion of GOHAI status in type 2 DM patients in this study (p=0.032). Type 2 DM patients with ≥20 teeth had a more significant proportion of high GOHAI status compared to those with <20 teeth. The majority of type 2 DM outpatients of Yogyakarta General Hospital had poor OHRQoL as reflection of their oral condition that is partly contributed by patients with present teeth <20.
Tongue coating index as a risk factor of decline of taste sensitivity in the elderly population Fimma Naritasari; Dewi Agustina; Fania Chairunisa; Lisdrianto Hanindriyo; Elastria Widita; Iffah Mardhiyah
Majalah Kedokteran Gigi Indonesia Vol 7, No 3 (2021): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.54935

Abstract

The elderly had various oral health issues, one of which is taste sensitivity. Taste sensitivity is highly affected by a person’s health, medication, eating habits, nutritional status, and oral hygiene. As an important organ for the sense of taste, the tongue can be covered in a white coating of debris, bacteria, and dead cells. To clean the tongue coating, one can do tongue brushing procedure, but this practice is not common among the elderly, especially in Indonesia. This cross-sectional study involved 114 older adults (n= 114) in the Special Region of Yogyakarta (Daerah Istimewa Yogyakarta- DIY), Indonesia, who were selected using stratified random sampling. The participants first signed the informed consent before undergoing an interview and going through oral clinical examination. This research particularly measured the tongue coating index and taste sensitivity level by way of statistically analyzing both variables to determine the correlation between tongue coating index and taste sensitivity level using three-dropmethod. Data from 114 subjects were presented descriptively using table and graphic. Most of the subjects 90.53% (103 subjects) had a coated tongue with various degree. The correlation statistic between tongue coating index and taste sensitivity level showed the statistically significant correlation (p-value = 0.019) and the coefficient correlation was -0.216, which means that there was a negative and weak correlation between both. Elderly with a higher tongue coating index tended to have less taste sensitivity. This could be due to debris blocking taste buds, thereby reducing taste sensitivity.