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All Journal Medicina Buletin Udayana Mengabdi E-Jurnal Medika Udayana Jurnal Veteriner The Indonesian Biomedical Journal Jurnal Kesehatan Husada Mahakam: Jurnal Kesehatan Journal of Global Pharma Technology
Ni Luh Putu Eka Diarthini
Department Of Parasitology, Faculty Of Medicine, Udayana University, Denpasar, Bali
Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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A Brief Review of Probiotic: Action Mechanism, Benefits, and Clinical Application on Human Health Dewa Ayu Agus Sri Laksemi; I Ketut Tunas; Ni Luh Putu Eka Diarthini
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
Publisher : Journal of Global Pharma Technology

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Abstract

Probiotics are live microorganisms that are commonly used as food supplementation to provide a positive impact on human health. There was an increasing number of studies concerned with the benefit of probiotics due to the enhance community awareness of health. The primarily role of probiotics are known strengthening the epithelial barrier, increasing attachment to the intestinal mucosa, inhibiting the attachment of pathogenic bacteria, competitive exclusion of pathogenic microorganisms, producing anti-microbial substances and thereby modulating host immunity by initiating specific genes activation in the host intestinal tract system. The benefits of probiotics are not only limited to the gastrointestinal system but the mechanism of action includes other organs such as respiratory, urogenital, endocrine, and immune system. Hence, this review study will focus mainly on three aspects such as benefits, action mechanism, and its clinical application of probiotics on human health.Keywords: Action mechanism, Benefits, Clinical application, Probiotics.
Co-Authors Amaze Morato Anak Agung Ayu Mirah Adi Desak Ketut Indrasari Utami Dewa Ayu Agus Sri Laksmi I Gusti Agung Komang Diafari Djuni Hartawan I Gusti Kamasan Arijana I Kadek Swastika I Ketut Tunas I Made Sudarmaja I NYOMAN MANTIK ASTAWA Ida Ayu Dewi Wiryantini Ida Bagus Satriya Wibawa Lisa Amelia Wijaya Made Indira Dianti Sanjiwani Morato, Amaze Grace Davidz Ni Luh Ariwati Ni Putu Wardani Putu Ayu Asri Damayanti