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Journal : Jurnal Respirologi Indonesia

Outcomes Prediction Using qSOFA, SpO2 / FiO2 and Procalcitonin of Pneumonia Sepsis Patients In Lung Ward at Dr. M.Djamil Padang Hospital Irawan, Eka; Medison, Irvan; Khairsyaf, Oea; Anggraini, Fenty
Jurnal Respirologi Indonesia Vol 42, No 1 (2022)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v42i1.268

Abstract

Background: Sepsis is a systemic inflammatory response to severe infections, sepsis is a major cause of morbidity and mortality. This study aims to determine the outcome prediction using qSOFA, SpO2/FiO2 Rasio and Procalcitonin in sepsis pneumonia patients in Lung ward of Dr. M DJamil Padang Hospital. Methods: Cohort study design with correlative analytics for 43 pneumonia sepsis patiens in Lung ward at Dr. M. Djamil Padang Hospital from September 2019 until to Februari 2020. Samples were taken by consecutive sampling method. Results: There were a significant relationship between qSOFA score with procalcitonin (p value = 0.006). There were no significant relationship between SpO2/FiO2 Rasio with procalcitonin (p value = 0.128). There were a significant relationship between qSOFA scores with patient outcomes (p value = 0.036), there were no significant relationship between procalcitonin with patient outcomes (p value = 0.205), and there were a significant relationship betweenSpO2/FiO2 Rasio with patient outcomes (p value = 0.019). Conclusion: qSOFA and SpO2 / FiO2 Rasio can predict the outcomes of patients with sepsis pneumonia 
Association Between Ferritin Levels and Sepsis in Patients with COVID-19 at Dr. M. Djamil Hospital Asrini, Diana Nur; Khairsyaf, Oea; Afriani, Afriani
Jurnal Respirologi Indonesia Vol 44 No 1 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i1.545

Abstract

Background: Ferritin is an important mediator of immunomodulatory dysregulation and pro-inflammatory effects, which contribute to cytokine storms that could lead to sepsis in a critically ill patients with COVID-19. The role of ferritin as a biomarker of sepsis in those patients is yet fully understood. The aim of this study is to investigate an association between ferritin levels and sepsis in patients with COVID-19.Method: This study was a retrospective, cross-sectional study of 474 COVID-19 hospitalized patients at Dr. M. Djamil Hospital, Padang.Result: Most of the COVID-19 patients in this study were between the ages of 18 and 49 (38,61%), female (55.91%), with moderate clinical illness (40.50%), and had one comorbidity (41,14%) with obesity as the most common comorbidity (37.97%). More than half of patients (54,22%) had ferritin levels of ≥500 ng/mL (median 1,201 ng/mL with a range of 503–12,010 ng/mL). The incidence of sepsis was significantly higher in the group whose ferritin level was ≥ 500 ng/ml compared to those with less ferritin level (P<0.001; OR=3.33; 5.99% vs 17.91%; CI 95%=1.74-6.36).Conclusion: There is a statistically significant association between the ferritin level and sepsis in patiens with COVID-19 at DR M Djamil Hospital.