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Hubungan Derajat Merokok Dengan Derajat Eksaserbasi Asma Pada Pasien Asma Perokok Aktif di Bangsal Paru RSUP DR. M. Djamil Padang Tahun 2007 - 2010 Syandrez Prima Putra; Oea Khairsyaf; Julizar Julizar
Jurnal Kesehatan Andalas Vol 2, No 3 (2013)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v2i3.163

AbstrakPrevalensi asma dan perokok aktif di Indonesia semakin meningkat. Penyakit asma dapat menurunkan kualitas hidup dan menimbulkan kematian terutama pada perokok aktif jika eksaserbasi asma berat terjadi. Penelitian ini bertujuan untuk melihat bagaimana hubungan antara derajat merokok dengan derajat eksaserbasi asma pada pasien asma perokok aktif. Penelitian analitik telah dilakukan dengan menggunakan data deskriptif di Bangsal Paru RSUP Dr. M. Djamil Padang pada bulan Desember 2011 sampai Januari 2013. Data yang dikumpulkan berasal dari catatan rekam medik pasien asma di Bangsal Paru sejumlah 228 orang. Sampel ditetapkan dengan menggunakan teknik total sampling sehingga didapatkan sampel sebanyak lima puluh orang. Untuk melihat hubungan antara derajat merokok dengan derajat eksaserbasi asma digunakan uji korelasi Spearman. Hasil Penelitian menunjukkan 51 dari 228 dari pasien asma (22,4%) adalah perokok aktif. Secara umum pasien memiliki derajat merokok sedang (41,18%) dan derajat eksaserbasi asma sedang (78,43%). Berdasarkan analisis statistik didapatkan nilai p = 0,275 (p<0,05) yang berarti tidak ada hubungan yang bermakna antara derajat merokok dengan derajat eksaserbasi asma.Kata kunci: merokok, eksaserbasi, asmaAbstractPrevalence of asthma and active smokers in Indonesia has increased. Asthma can reduce quality of life and lead to death especially in active smokers if the severe asthma exacerbation occur. This study aims to look at how the correlation between the degree of smoking by the degree of asthma exacerbation in active smoker patients with asthma. Analytic studies have been conducted using the descriptive data in Pulmonary Ward of RSUP Dr. M. Djamil Padang in December 2011 to January 2013. Data collected from the medical records of patients with asthma history in Pulmonary Ward for 228 people. The samples were appointed by using total sampling technique, so obtained the samples about fifty people. Spearman correlation test was used to examine the relationship between the degree of smoking by the degree of asthma exacerbation. The results of this study showed 51 of 228 of the patients with asthma (22.4%) were active smokers. In general, patients had a moderate degree of smoking (41.18%) and moderate degree of asthma exacerbations (78.43%). The statistical analysis was obtained p-value = 0.275 (p<0,05) which means there is no significant correlation between the degree of smoking by the degree of asthma exacerbation.Keywords: smoking, exacerbation, asthma

PEMBERDAYAAN MASYARAKAT DI NAGARI LUMPO KABUPATEN PESISIR SELATAN Yusrawati Yusrawati; Yulizawati Yulizawati; Lusiana El Sinta Bustami; Aldina Ayunda Insani; Vaulinne Basyir; Hudila Rifa Karmila; Feni Andriani; Erda Mutiara Halida; Fitrayeni Fitrayeni; Uliy Iffah; Miranie Safaringga; Laila Rahmi; Rafika Oktova; Ulfa Farah Lisa; Muhammad Iqbal; Rahmat Syawqi; Syandrez Prima Putra; Liganda Endo Mahata; Elfira Yusri
BULETIN ILMIAH NAGARI MEMBANGUN Vol 2 No 4 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Pesisir Selatan Regency is one of the districts with 15 sub-districts with the largest population in IV Jurai District. The number of deaths per year on the South Coast fluctuates. In 2015 the number of infant deaths increased from 6 to 42 people (male 29 and 13 female) from the previous year, AKABA of 47 from 18 in the previous year. There were 16 toddlers with herniated nutrition and many pregnant women, namely around 273 pregnant women. Based on a preliminary study conducted by the activity implementation team at the Lumpo Public Health Center, IV Jurai District, Pesisir Selatan Regency, it is known that there is no ultrasound examination facility in pregnancy and prenatal yoga facilities at the Lumpo Puskesmas, besides that there are no similar activities carried out at SD Negeri 016 and MTsN. Nagari Lumpo which is included in the work area of Lumpo Puskesmas. Several tests can be done during pregnancy as an effort to detect early and prevent complications and growth disorders in the fetus. Among others, by monitoring weight gain during pregnancy, conducting general examinations (vital signs), physical examinations that focus on the breasts, abdomen, genitalia with inspection, palpation, auscultation, and percussion, ultrasonography (USG) examinations, and performing supporting examinations in the form of laboratory examination (hemoglobin examination). The result of this activity is an increase in each target group's quality of life by the stages of life after this activity.

Upaya Pencegahan Kanker Serviks melalui Vaksinasi dan Skrining Human Papillomavirus Syandrez Prima Putra
Majalah Kedokteran Andalas Vol 44, No 2 (2021): Online July 2021
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v44.i2.p125-133.2021

Kanker serviks masih menjadi salah satu penyebab kesakitan dan kematian tertinggi pada perempuan secara global akibat keganasan. Infeksi human papillomavirus (HPV) risiko tinggi (high-risk HPV/ hrHPV) terutama HPV 16 dan 18 merupakan penyebab etiologis terjadinya kanker serviks. Pemanfaatan vaksin HPV baik bivalen, quadrivalen, dan generasi terbaru 9-valen dinilai efektif untuk mencegah terjadinya kanker serviks di negara-negara maju, sementara di negara-negara berkembang masih terkendala dengan sumber daya yang terbatas. Disamping vaksinasi, skrining kanker serviks masih penting untuk dilakukan untuk preventif. Deteksi dini secara sitologis menggunakan Pap smear merupakan metode konvensional dengan sensitifitas dan spesifisitas yang tinggi, namun sulit diterapkan di negara-negara berkembang. Inspeksi visual asam asetat (tes IVA) menjadi alternatif pemeriksaan sitologis yang lebih murah, namun akurasinya untuk identifikasi lesi prakanker masih diperdebatkan. Tes DNA HPV saat ini menjadi pilihan pencegahan kanker serviks terbaru yang uji sensitiftas dan spesifisitasnya mampu menyamai Pap smear pada kasus neoplasia intraepitelial serviks (CIN) +2 dan +3. Jadwal skrining yang lebih sedikit dan adanya peluang untuk melakukan pengambilan sampel secara mandiri membuat tes HPV sangat ideal untuk dimasukkan pada program pencegahan primer pada negara berkembang. Tinjauan ini bertujuan untuk memaparkan kondisi terbaru mengenai epidemiologi kanker serviks dan upaya preventif terkini yang lebih efektif.

Correlation Of Neutrophil Lymphocyte Ratio And Platelet Lymphocyte Ratio With Severity Of COVID-19 Warman, Fadil Ahmadhia; Yulia, Dwi; Kadri, Husnil; Mulyana, Roza; Yusri, Elfira; Putra, Syandrez Prima
Majalah Kedokteran Andalas Vol 46, No 9 (2024): Supplementary Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i9.p1361-1375.2024

The neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) tests are simple tests can be done before a COVID-19 patient hospitalized. This examination is useful for determining the diagnosis and prognostic of the patient. The aim of the study was to determine the correlation between NLR and PLR with the severity of COVID-19. This research was an analytical study with a cross-sectional approach using secondary data from 289 medical records of patients with confirmed COVID-19 for the period June-August 2021. The total sampling technique was used and processed with the chi-square test. Most of the research subjects were in the range of 26-45 years (28.4%). More than half of the subjects were female (61.6%). There were 99 patients (34.3%) with severe conditions. Less than half of the patients had abnormal leukocyte and platelet examination results, namely 64 (22.1%) and 56 (19.4%). Patients with abnormal NLR and PLR examinations were 135 (46.7%) and 123 (42.6%). There was a significant correlation between NLR and the severity of COVID-19 inpatients (p<0.001, OR=9.452). There is a significant correlation between PLR and the severity of COVID-19 inpatients (p<0.001, OR=7.268). This study concludes a significant correlation between NLR and PLR with the severity of COVID-19.

Hubungan Tingkat Aktivitas Penyakit Lupus Eritematosus Sistemik dengan Derajat Gangguan Fungsi Ginjal pada Pasien Lupus Eritematosus Sistemik Nabila, Fathiya Sarah; Miro, Saptino; Effendi, Rinal; Almurdi, Almurdi; Yulia, Dwi; Putra, Syandrez Prima
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 2 (2024): Juni 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i2.1103

Abstrak Latar Belakang: Evaluasi fungsi ginjal dan pemantauan aktivitas penyakit pada pasien lupus eritematosus sistemik (LES) diperlukan untuk mendeteksi penyakit LES secara dini. Penilaian aktivitas penyakit juga berperan penting dalam memandu pemberian terapi yang tepat agar memberikan hasil yang lebih baik. Objektif: Mengetahui hubungan antara tingkat aktivitas penyakit LES dengan derajat gangguan fungsi ginjal pada pasien LES. Metode: Penelitian ini merupakan penelitian analitik dengan pendekatan cross-sectional menggunakan data sekunder dari rekam medis pasien LES di Departemen Penyakit Dalam RSUP Dr. M. Djamil Padang. Teknik pengambilan sampel adalah consecutive sampling dengan total sampel 70 pasien LES. Analisis data dilakukan dengan menggunakan chi-squared test. Hasil: Terdapat 98,6% pasien berjenis kelamin perempuan, 48,9% pasien berada pada kelompok usia 17–25 tahun, rerata kadar serum kreatinin 1,756±3,3437 mg/dl, 65,7% pasien memiliki fungsi ginjal normal, 70% pasien memilliki tingkat aktivitas penyakit LES sedang, dan hasil uji statistik antara tingkat aktivitas penyakit LES dengan derajat gangguan fungsi ginjal pada pasien LES adalah menunjukkan nilai p=0,081. Kesimpulan: Mayoritas pasien berjenis kelamin perempuan, kelompok usia terbanyak yaitu usia 17 – 25 tahun, rerata kadar serum kreatinin 1,756±3,3437 mg/dl, mayoritas memiliki derajat fungsi ginjal yang normal, tingkat aktivitas penyakit LES sedang, dan tidak terdapat hubungan yang signifikan antara tingkat aktivitas penyakit LES dengan derajat gangguan fungsi ginjal pada pasien LES. Kata kunci: tingkat aktivitas penyakit, derajat gangguan fungsi ginjal, lupus eritematosus sistemik Abstract Background: Evaluation of kidney function and monitoring the disease activity in patients with systemic lupus erythematosus (SLE) are necessary for early detection of the SLE disease. Assessment of disease activity also plays an important role in providing a better therapy. Objective: This study aims to determine the relationship between SLE disease activity and the stages of kidney disease in SLE patients. Methods: This study is an analytical study with a cross-sectional approach using secondary data from the medical records of SLE patients in the Internal Medicine Department of Dr. M. Djamil Padang Hospital. The sampling technique is consecutive sampling with a total sample of 70 SLE patients. Data analysis was performed using chi-squared test. Results: There were 98.6% of the patients were female, 48.9% of the patients were in the age group of 17–25 years, the mean serum creatinine level was 1.756±3.3437 mg/dl, 65.7% of the patients had normal kidney function, 70% of the patients had a moderate level of LES disease activity, and the results of a statistical test between the level of activity of LES disease and the stages of kidney disease in SLE patients showed a value of p=0.081. Conclusion: The majority of patients were female, the largest age group was 17-25 years old, the average serum creatinine were 1,756±3,3437 mg/dl, majority of patients had a normal kidney function, had a moderate level of SLE disease activity, and there was no significant relationship between level of SLE disease activity and stages of kidney disease in SLE patients. Keyword: disease activity, stages of kidney disease, systemic lupus erythematosus

PEMBERDAYAAN MASYARAKAT DI NAGARI LUMPO KABUPATEN PESISIR SELATAN Yusrawati Yusrawati; Yulizawati Yulizawati; Lusiana El Sinta Bustami; Aldina Ayunda Insani; Vaulinne Basyir; Hudila Rifa Karmila; Feni Andriani; Erda Mutiara Halida; Fitrayeni Fitrayeni; Uliy Iffah; Miranie Safaringga; Laila Rahmi; Rafika Oktova; Ulfa Farah Lisa; Muhammad Iqbal; Rahmat Syawqi; Syandrez Prima Putra; Liganda Endo Mahata; Elfira Yusri
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 2 No. 4 (2019)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v2i4.130

Pesisir Selatan Regency is one of the districts with 15 sub-districts with the largest population in IV Jurai District. The number of deaths per year on the South Coast fluctuates. In 2015 the number of infant deaths increased from 6 to 42 people (male 29 and 13 female) from the previous year, AKABA of 47 from 18 in the previous year. There were 16 toddlers with herniated nutrition and many pregnant women, namely around 273 pregnant women. Based on a preliminary study conducted by the activity implementation team at the Lumpo Public Health Center, IV Jurai District, Pesisir Selatan Regency, it is known that there is no ultrasound examination facility in pregnancy and prenatal yoga facilities at the Lumpo Puskesmas, besides that there are no similar activities carried out at SD Negeri 016 and MTsN. Nagari Lumpo which is included in the work area of Lumpo Puskesmas. Several tests can be done during pregnancy as an effort to detect early and prevent complications and growth disorders in the fetus. Among others, by monitoring weight gain during pregnancy, conducting general examinations (vital signs), physical examinations that focus on the breasts, abdomen, genitalia with inspection, palpation, auscultation, and percussion, ultrasonography (USG) examinations, and performing supporting examinations in the form of laboratory examination (hemoglobin examination). The result of this activity is an increase in each target group's quality of life by the stages of life after this activity.

Profil Pasien Luka Bakar dengan Syok Hipovolemik di RSUP Dr. M. Djamil Padang Tahun 2019-2021 Addina, Azka; Saputra, Deddy; Manela, Citra; Fortuna, Fory; Elvira, Dwitya; Putra, Syandrez Prima
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 2 (2025): Juni 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i2.1304

Latar Belakang: Syok hipovolemik adalah suatu keadaan gawat darurat pada luka bakar yang meningkatkan risiko kematian. Pemahaman tentang karakteristik pasien luka bakar dengan syok hipovolemik sangat penting untuk mempercepat penegakan diagnosis dan menurunkan risiko mortalitas. Objektif: Penelitian ini bertujuan untuk menilai karakteristik pasien luka bakar yang mengalami syok hipovolemik. Metode: Penelitian ini merupakan penelitian deskriptif dengan desain cross sectional. Teknik pengambilan sampel menggunakan total sampling. Variabel yang diteliti adalah usia, jenis kelamin, penyebab, derajat luka, luas luka, komorbid, dan fasilitas kesehatan asal. Data penelitian diambil dari data sekunder rekam medis di Instalasi Rekam Medis RSUP Dr. M. Djamil Padang tahun 2019-2021. Analisis data dilakukan menggunakan analisis univariat yang dilakukan pada setiap variabel penelitian. Hasil: Sebanyak 30 pasien luka bakar dengan syok hipovolemik diikutsertakan ke dalam penelitian. Kasus terbanyak ditemukan pada kelompok usia 36-45 tahun, laki-laki, luka bakar api, derajat full thickness, luas luka 20-39% dan 40-59% TBSA, komorbid penyakit paru, serta rujukan dari rumah sakit tipe C. Kesimpulan: Risiko kejadian syok hipovolemik perlu diwaspadai pada kasus luka bakar usia dewasa akhir, luka bakar pada laki-laki, luka bakar akibat api, luka bakar dengan derajat full thickness serta luka bakar mayor, dan pada kasus dengan komorbid paru.

Correlation Of Neutrophil Lymphocyte Ratio And Platelet Lymphocyte Ratio With Severity Of COVID-19 Warman, Fadil Ahmadhia; Yulia, Dwi; Kadri, Husnil; Mulyana, Roza; Yusri, Elfira; Putra, Syandrez Prima
Majalah Kedokteran Andalas Vol. 48 No. 2 (2025): MKA April 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i2.p125-137.2025

The neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) tests are simple tests can be done before a COVID-19 patient hospitalized. This examination is useful for determining the diagnosis and prognostic of the patient. The aim of the study was to determine the correlation between NLR and PLR with the severity of COVID-19. This research was an analytical study with a cross-sectional approach using secondary data from 289 medical records of patients with confirmed COVID-19 for the period June-August 2021. The total sampling technique was used and processed with the chi-square test. Most of the research subjects were in the range of 26-45 years (28.4%). More than half of the subjects were female (61.6%). There were 99 patients (34.3%) with severe conditions. Less than half of the patients had abnormal leukocyte and platelet examination results, namely 64 (22.1%) and 56 (19.4%). Patients with abnormal NLR and PLR examinations were 135 (46.7%) and 123 (42.6%). There was a significant correlation between NLR and the severity of COVID-19 inpatients (p<0.001, OR=9.452). There is a significant correlation between PLR and the severity of COVID-19 inpatients (p<0.001, OR=7.268).Â This study concludes a significant correlation between NLR and PLR with the severity of COVID-19.

GAMBARAN TINGKAT PENGETAHUAN MASYARAKAT TENTANG KEJADIAN IKUTAN PASCA IMUNISASI (KIPI) COVID-19 DI KOTA SOLOK Adhima Indriyani; Eryati Darwin; Syandrez Prima Putra; Nita Afriani; Firdawati Firdawati
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 6 (2026): SINERGI : Jurnal Riset Ilmiah, Juni 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i6.2677

Covid-19 is an infectious disease caused by SARS-CoV-2 virus. Many people are worried about getting vaccinated because they received false rumors about KIPI Covid-19 which can cause death by using several types of vaccines. Objective: This study aims to describe the level of public knowledge about Covid-19 Post-Immunization Follow-up Events (KIPI) in Solok City. Methode: This research is a quantitative descriptive study, which is to see a variable description of the level of public knowledge regarding KIPI Covid-19 based on the characteristics of respondents. Sampling using simple random sampling method on 100 respondents. Result: In this study, the results were obtained: only 36% of respondents had received the third dose of Covid-19 vaccination, 52% of respondents had insufficient knowledge regarding KIPI Covid-19, and 57% of respondents experienced Covid-19 Post Immunization Follow-Up Events (KIPI). There is no association between gender, age, education level, and employment status with knowledge of Covid-19 Post Immunization Follow-Up Events (KIPI). There is a significant association between vaccination status with knowledge of Covid-19 Post Immunization Follow-Up Events (KIPI). Conclusion: There were more respondents who have less knowledge (more than half of the respondents). When viewed from the vaccination status, more respondents with less knowledge got vaccinated up to the second dose.

PENGARUH PEMBERIAN PARE (MOMORDICA CHARANTIA) TERHADAP PERUBAHAN HISTOPATOLOGIS PADA USUS TIKUS YANG TERINFEKSI ESCHERICHIA COLI Sabrina Herfika Putri; Alimuddin Tofrizal; Elmatris Sy; Aswiyanti Asri; Rauza Sukma Rita; Syandrez Prima Putra
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 4 (2026): SINERGI : Jurnal Riset Ilmiah, April 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i4.2469

Bitter melon (Momordica charantia) has been empirically proven for antimicrobial properties that can be used as an alternative medicine, while the changes that occur in Escherichia coli-infected mouse intestine after administering bitter melon have not been widely studied. The aim of this study was to determine the effect of Momordica charantia administration on histopathology of intestine of E. coli infected mice. This research was post-test control randomized group study involving 20 mice’s small intestine paraffin blocks which were divided into 4 groups consisted of control and different dosage of bitter melon juice, observed subsequently under a microscope to measure the of the small intestine lining and assess inflammation using modified Barthel Mandja scoring. This study found significant changes the height of mucosa and villi of mice small intestine after administration of 100 grams of bitter melon juice and the muscle layer and crypts after administration of 200 grams of bitter melon juice. The Barthel Manja score showed decrease of inflammation degree among P2 group, while increased inflammation degree found in P3 group. It can be concluded that administration of bitter melon juice has the potential to improve the intestinal histopathology of mice infected with Escherichia coli.

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