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All Journal Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati BIOSFER : Jurnal Biologi dan Pendidikan Biologi Indonesian Journal of Islamic History and Culture Indonesian Journal of Fundamental Sciences Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Bionature
Alimuddin Ali
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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Journal : Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan

 1 
PENGARUH VARIASI KONDISI FERMENTASI TERHADAP PRODUKSI METABOLIT ANTIBAKTERI EKSTRAK ISOLAT I5 FUNGI ENDOFIT Anredera cordifolia (Ten.) Steenis Ismail Ismail; Megawati Megawati; Alimuddin Ali; Fuji Asmiati Ningsih
Jurnal Ilmiah Manuntung Vol 5 No 2 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i2.260

Abstract

Endophytic fungi are one of the microorganisms that live in plants and symbiotic with their host plant produce secondary metabolites. This study aims to determine the optimum growth profile of endophytic fungus isolated from the leaf of Anredera cordifolia (Ten.) Steenis namely isolate I5 as antibacterial. The fungus growth profile optimization analyzed by a correlation between fermentation time and mycelium weight, which collected every 24 hours for 15 days. The media were varied at pH conditions of 4, 7, and 8 in each PDYB medium (glucose and fructose substrates). The results showed that isolate I5 grew optimally on the 13th day on the PDYB medium pH 8. Ethyl acetate extract 5% of isolate I5 could inhibit bacteria growth with the largest inhibition zone diameter against Staphylococcus aureus of 9.96 mm (± 0.60) and Escherichia coli of 9.03 mm (± 0.46).
Co-Authors Adnan Andi Mu'nisa Andi Muflihunna Darminto Darminto, , Dwi Rahayu Dini Endang Sutariningsih Soetarto Fuji Asmiati Ningsih Ismail Ismail Iwan Dini J. Sri Widada M. Junda Megawati Megawati Nani Kurnia Nur Istiqamah Nurhayati B Yahdiel Ronrong