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All Journal Journal of Experimental and Clinical Pharmacy (JECP) Indonesian Journal of Fundamental Sciences
Andi Muflihunna
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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EFEK AIR REBUSAN KAYU CINA (Lannea coromandelica) TERHADAP HISTOPATOLOGI MUKOSA LAMBUNG MENCIT (Mus musculus) YANG DIINDUKSI ASAM KLORIDA (HCl) Andi Mu'nisa; Alimuddin Ali; M. Junda; Andi Muflihunna; Nur Istiqamah
Indonesian Journal of Fundamental Sciences Vol 5, No 1 (2019)
Publisher : Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.74 KB) | DOI: 10.26858/ijfs.v5i1.9370

Abstract

Penelitian ini bertujuan untuk mengetahui efek air rebusan kayu cina terhadap histopatologi mukosa lambung mencit (mus musculus) yang diinduksi asam klorida (HCl). Penelitian ini menggunakan mencit jantan strain ICR sebanyak 45 ekor yang dibagi dalam 3 kelompok perlakuan, yaitu kelompok mencit normal, kelompok mencit gastritis, dan kelompok mencit dengan pemberian air rebusan kayu cina selama 7 dan 14 hari sebanyak 0.3 cc. Hasilnya menunjukkan bahwa setelah pemberian air rebusan kayu cina ada perbaikan sel-sel mukosa lambung mencit. Kesimpulan dalam penelitian ini adalah bahwa air rebusan kayu cina menunjukkan adanya perbaikan secara histopatologis mukosa lambung mencit yang diinduksi asam klorida (HCl).
Comparative Antioxidant Capacity of Seed and Fruit Ethanol Extracts of Bitter Melon (Momordica charantia L.) Using FRAP Assay Luysi Ariani; Faradiba Abdul Rasyid; Dewi Yuliana; Rahmawati Rahmawati; Andi Muflihunna; Asni Amin; Rezki Amriati Syarif
Journal of Experimental and Clinical Pharmacy (JECP) Vol 6, No 1 (2026): February 2026
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v6i1.1628

Abstract

Momordica charantia L. (bitter melon) is traditionally consumed as both food and medicine in Indonesia. Its fruit and seeds contain bioactive compounds such as saponins, flavonoids, polyphenols, and unsaturated fatty acids with recognized antioxidant potential. This study compared the antioxidant activity of ethanol extracts from bitter melon seeds and fruit using the Ferric Reducing Antioxidant Power (FRAP) assay. Extraction was conducted by ultrasound-assisted extraction (UAE) with ethanol as solvent, and antioxidant activity was expressed as quercetin equivalents (mg QE/g extract). The seed extract showed an antioxidant value of 8.680 mg QE/g, while the fruit extract exhibited 8.626 mg QE/g. The statistical analysis showed that the p-value was greater than 0.05, indicating no significant difference between the two extracts. This suggests that both extracts exhibit comparable antioxidant activity. These results highlight that both seeds and fruit of M. charantia may serve as promising natural antioxidant sources for functional food and pharmaceutical applications.
Co-Authors Abdul Rasyid, Faradiba Alimuddin Ali Andi Mu'nisa Asni Amin Dewi Yuliana Luysi Ariani M. Junda Nur Istiqamah Rahmawati Rahmawati Rezki Amriati Syarif