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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Inovasi Pendidikan IPA E-Dimas: Jurnal Pengabdian kepada Masyarakat Jurnal SOLMA PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal PkM (Pengabdian kepada Masyarakat) Pharmaceutical And Biomedical Sciences Journal (PBSJ)

Yeni Yeni

Universitas Muhammadiyah Prof. Dr. HAMKA

Author-ID : 2988785

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Public Health Social Sciences Other

Published : 8 Documents Claim Missing Document

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Articles

In silico toxicity prediction of 1-phenyl-1-(quinazolin-4-yl) ethanol compounds by using Toxtree, pkCSM and preADMET Yeni Yeni; Supandi Supandi; Fajar Merdekawati
Pharmaciana Vol 8, No 2 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

The 1-phenyl-1-(quinazolin-4-yl) ethanol compounds are alkaloids of quinozoline class found in many Hydrangeaceae families. A survey revealed that most of the identified quinazolin derivatives have anticancer activity. Toxicity prediction of 1-phenyl-1-(quinazolin-4-yl) ethanols were performed to obtain the best three compounds with high activity and the lowest toxicity. Toxicity prediction was conducted using Toxtree, pkCSM and PreADMET. 2D structure of compounds were formed using ChemDraw. The decision tree approach was used in Toxtree application with endpoints including Cramer rules, Kroes TTC, carcinogenicity (genotoxic and non genotoxic) and in vitro mutagenicity. Graph based signature was used in pkCSM application with endpoints including mutagenicity, maximum daily dose, LD50 and hepatotoxicity. In PreADMET application, a method based on drugs similarity and ADMET properties was used with endpoints including mutagenicity, carcinogenicity to rat and mice. The results of data analysis showed that the best three anticancer compounds that have high activity and the lowest toxicity are compounds 14, 16 and 19.

Pelatihan Pembuatan Lilin Aromaterapi sebagai Tambahan Keterampilan Andikpas di LPKA Kelas II Bandung Nining Nining; Yeni Yeni
E-Dimas: Jurnal Pengabdian kepada Masyarakat Vol 12, No 1 (2021): E-DIMAS
Publisher : Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/e-dimas.v12i1.3393

LPKA Kelas II Bandung merupakan lembaga pendidikan bagi anak yang berkonflik dengan hukum di daerah Provinsi Jawa Barat. Berbagai upaya pembinaan dilakukan LPKA berkerjasama dengan berbagai pihak salah satunya adalah Perguruan Tinggi sebagai tenaga pengajar kegiatan non-formal. Kegiatan pelatihan pembuatan lilin aromaterapi ditujukan untuk menambah keterampilan para peserta anak didik pemasyarakatan (andikpas) sebagai bekal keterampilan individu sehingga dapat digunakan kelak setelah kembali ke lingkungan masyarakat. Kegiatan diawali dengan trial pembuatan produk di laboratorium sebelum pelaksanaan pelatihan. Pelatihan disampaikan dalam bentuk presentasi dan dilanjutkan dengan praktik pembuatan lilin aromaterapi secara eksperimentatif dalam berbagai variasi bentuk. Produk berupa lilin aromaterapi yang berfungsi ganda, yaitu sebagai alat penerangan, media terapi dan penyegar ruangan. Kegiatan pelatihan membuat suatu produk yang memiliki nilai ekonomis tinggi melalui pembuatan lilin aromaterapi berbasis soy wax dalam wadah gelas dapat memiliki nilai jual yang tinggi. Hasil pengabdian menunjukkan bahwa kegiatan pelatihan mampu memotivasi peserta andikpas untuk berwirausaha dan peserta antusias mengikuti selama kegiatan pelatihan berlangsung.

Pembuatan Sabun Scrub Kopi sebagai Produk Souvenir Komoditas Lokal di Desa Kaliaren Kabupaten Kuningan Nining Nining; Yeni Yeni
Jurnal SOLMA Vol. 7 No. 2 (2018)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Peningkatan serapan kopi oleh industri merupakan strategi yang perlu dilakukan dalam memperluas diversifikasi produk kopi. Serapan kopi produksi Indonesia berkisar sekitar 35% dan sisanya masih diekspor. Desa Kaliaren merupakan salah satu desa di Kecamatan Cilimus Kabupaten Kuningan yang wilayahnya banyak ditanami kopi. Selama ini, penjualaan kopi oleh para petani secara langsung hanya dalam kondisi segar. Oleh karena itu, perlu dilakukannya suatu usaha untuk memvariasikan produk olahan kopi setempat. Salah satu usaha tersebut adalah memberdayakan masyarakat agar mampu secara mandiri memanfaatkan potensi daerahnya yaitu dengan pengetahuan dan keterampilan mengenai wirausaha dan teknologi tepat guna proses pembuatan sabun scrub kopi yang dapat dijadikan produk souvenir komoditas lokal. Dari hasil kegiatan yang telah dilakukan dapat ditarik kesimpulan bahwa: (1) Kegiatan PKM ini dapat meningkatkan motivasi usaha, kesadaran, pengetahuan dan ketrampilan masyarakat melalui penerapan teknologi tepat guna untuk mengolah komoditas lokal menjadi produk sabun scrub; (2) Peserta pelatihan kelompok ibu-ibu PKK dan KWT telah mengikuti serangkaian kegiatan pembuatan sabun scrub selanjutnya perlu dikembangkan kerjasama dengan pihak terkait untuk pengembangan bisnis sabun scrub ke depannya.

Anti-Parkinson Drug from Chemical Medicines and Herbal Medicines: A Review Yeni Yeni; Xia Wu; Budi Arman
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 3, No 1 (2021)
Publisher : UIN Syarif Hidayatullah Jakarta

Parkinson's disease (PD) is a disease of the central nervous system. It is a progressive disorder, meaning it gets worse over time. PD usually characterized by tremor, rigidity, akinesia and postural autonomic instability. In addition, it may also cause a series of non-motor symptoms (NMSs). This disease affects a small area of cells in the middle of the brain. This area is called the substantia nigra (SNc). The cells slowly lose their ability to produce a chemical called dopamine. The disease usually appears in the age over 60 years. Nowadays, a lot of anti-Parkinson drugs have been found either from that of chemicals or herbs. In this essay anti-Parkinson drugs from chemical medicine and herbal medicines especially from china will be discussed. Anti-Parkinson's drugs are derived from chemical medicines include levodopa (l-dopa), dopamine agonists, MAO-B inhibitors, catechol O-methyltransferase (COMT) inhibitors, anticholinergics and amantadine. Meanwhile, anti-Parkinson drugs derived from herbal medicine include Scutellaria baicalensis Georgi, Polygonum cuspidatum Sieb. et Zucc., green tea (Camellia sinensis L.), Panax ginseng C. A. Mey., Cistanche deserticola Y. C. Ma, Panax Notoginseng Wall. var notoginseng (Burkill.) F.H. Chen, Gastrodia elata Blume and Polygala tenuifoliaWilld.. These drugs have the same effects to help ease symptoms of Parkinson’s and can increase the amount of dopamine in substantia nigra pars compacta (SNc). However, some chemical drugs have more side effects although herbal medicines are less clear, more tests need to be planned.

Potensi Limbah Kulit Biji Kopi dan Pemanfaatannya sebagai Produk Sabun Cair yang memiliki Aktivitas Antioksidan dan Antibakteri: Potential of Coffee Bean Peel Residue and Its Use in a Liquid Soap with Antioxidant and Antibacterial Fith Khaira Nursal; Anisa Amalia; Supandi Supandi; Nining Nining; Yeni Yeni
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 7 No. 6 (2022): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v7i6.4030

Numerous coffee plantation workers are members of the Neglasari village farmer group, located in Sukawangi village, Bogor district. The problem frequently raised is coffee bean residue, which is typically discarded and provides an idea for the group to consider using it. This issue can be remedied by providing knowledge and direction regarding possible coffee bean husk residues. According to earlier studies, coffee bean skin includes polyphenols with potential antibacterial and antioxidant properties, allowing it to be formulated into skin-safe liquid soap solutions. Participants are productive-age men and female farmers with a constant motivation for entrepreneurship. Participants were provided with a direct explanation of the possibilities of coffee bean husk residue, followed by a short training on manufacturing liquid soap. Comparing the outcomes of the pre-test and post-test provided to participants is an indication of the activity's efficacy. Based on the collected results, it can conclude that the participant's comprehension of the presented material increased significantly (p < 0.05). It anticipated that the outcomes of this product development education and training would enable Farmer Group members to become home-based entrepreneurs.

Is conceptual learning based on conceptual change text (CTT) effectively applied to PGSD students' science classes? Wati Sukmawati; Sri Lestari Handayani; Yeni Yeni
Jurnal Inovasi Pendidikan IPA Vol 7, No 2: Oktober 2021
Publisher : Faculty of Mathematics and Natural Sciences, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jipi.v7i2.44034

For Elementary School Teacher Education (PGSD) students, the introductory science concept course is part of the compulsory course. The understanding of PGSD students in basic science concepts will affect the quality of learning in the classroom. This research was conducted in odd semesters with 60 students who attended lectures on basic science concepts, and the sample selection was made randomly. To collect data on the effectiveness of the implementation of CCT, instruments used in the form of cognitive and clinical test questions have gone through validation and reliability tests. Students were divided into two groups in the study: the experimental group using CCT-based contextual learning as teaching materials and the control class using ordinary teaching materials. Based on the N-Gain data found in the field, there was a significant difference between the experimental and control groups; the control class had an N-Gain value of 0.54, while the experimental class was 0.81. The data revealed that learning using CCT successfully increased students' understanding of concepts in the material cycle and created a better environment compared to the control class. However, based on interview data, both experimental and control class students were interested in learning the concept of the energy cycle and environmental pollution, and there was no significant difference.

Penyuluhan Pemilihan dan Penggunaan Kosmetika yang Tepat dan Aman di Kalangan Remaja Yeni Yeni; Nining Nining
Jurnal PkM (Pengabdian kepada Masyarakat) Vol 6, No 4 (2023): Jurnal PkM: Pengabdian kepada Masyarakat
Publisher : Universitas Indraprasta PGRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30998/jurnalpkm.v6i4.9372

Pada usia remaja, penggunaan kosmetika merupakan kebutuhan yang penting. Bahan kimia dalam kosmetika belum tentu memberikan dampak yang sama pada semua konsumen. Beberapa kosmetika mengandung zat berbahaya, dan penggunaannya dalam kosmetika dilarang. Masalah yang dihadapi remaja dalam memilih dan menggunakan kosmetika mungkin karena kurangnya informasi tentang kosmetika yang tepat dan aman. Dalam penyuluhan ini, kami menjelaskan cara mengecek "KLIK" (Kemasan, Label, Izin edar dan Kadaluarsa) kosmetik dan memilih kosmetik yang benar dan aman. Peserta juga telah dijelaskan mengenai beberapa zat berbahaya yang mungkin ada di dalam kosmetika. Penyuluhan ini telah dilaksanakan pada tanggal 10 Januari 2021 dengan jumlah peserta 62 orang. Peserta diberikan pretest sebelum penyuluhan dan posttest setelah penyuluhan. Hasil pengujian menunjukkan ±13,4% peningkatan pengetahuan remaja tentang memilih dan menggunakan kosmetika yang tepat dan aman

Detergen Cair Ramah Lingkungan Berbasis Metil Ester Sulfonat (MES): STEM Project-Based Learning di SMA Muhammadiyah 9 Kota Bekasi Nining Nining; Yeni Yeni; Anisa Amalia
Amaliah: Jurnal Pengabdian Kepada Masyarakat Vol 8 No 1 (2024): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPI UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v8i1.2970

One of the problems related to the issue of damage to aquatic ecosystems due to environmental pollution in Indonesia is the use of surfactant-based detergents, which make it difficult for people to degrade naturally. Making environmentally friendly liquid detergent products made from MES surfactants can be a learning experience for students using the low-carbon STEM project-based learning model concept. This model is a more practical approach to developing creative thinking skills and is part of a learning community for continuous learning. This service activity is collaborative between universities and schools in applying STEM to chemistry learning. This activity is an alternative form of learning chemistry to stimulate students' fascination and interest in learning material, which is often considered challenging. The activity method uses group simulation and experimental methods to optimize material delivery. Based on evaluation data that was paired t-tested, there was a significant increase in students' understanding of the material (p<0.05) with an increase in the average test score from 40.44 to 89.56. Apart from that, most of the activity participants also showed active participation and enthusiasm.

Co-Authors Anisa Amalia Budi Arman Fajar Merdekawati Fith Khaira Nursal Nining Nining Nining, Nining Sri Lestari Handayani Supandi Supandi Supandi Wati Sukmawati Xia Wu Yulianindra Khalishah

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