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All Journal Jurnal Farmasi Udayana Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Sains dan Komunitas Nyimak: Journal of Communication Syntax Literate: Jurnal Ilmiah Indonesia Jurnal SOLMA JMM (Jurnal Masyarakat Mandiri) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan JSFK (Jurnal Sains Farmasi & Klinis) PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia JCPS (Journal of Current Pharmaceutical Sciences) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Peduli Masyarakat BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Abdimas Indonesia : Jurnal Abdimas Indonesia ALMUJTAMAE: Jurnal Pengabdian Masyarakat Jurnal Ilmu Gizi dan Dietetik Jurnal Pengabdian Masyarakat Bangsa Indonesian Journal of Pharmacy and Natural Product MARAS : Jurnal Penelitian Multidisplin Jurnal Pengabdian Farmasi dan Sains Jurnal Abdita Naturafarm

Anisa Amalia

Department Of Pharmaceutical Technology, Faculty Of Pharmacy And Science, Universitas Muhammadiyah Prof. DR. HAMKA, Jakarta 13460, Indonesia

Author-ID : 1229621

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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THE INFLUENCE OF B-CYCLODEXTRIN CONCENTRATIONS AS LIGANDS ON INCLUSION COMPLEXES TO INCREASE THE SOLUBILITY OF IBUPROFEN Rahmah Elfiyani; Anisa Amalia; Alvin Integra
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 17, No 1 (2020)
Publisher : Sanata Dharma University

Ibuprofen is a compound with low solubility but high permeability in water. One method to improve the ability of a substance to dissolve in water is through the formation of inclusion complexes. This study aims to obtain ratio between ibuprofen and b-cyclodextrin which results in inclusion complex with an optimal amount of dissolved ibuprofen. The inclusion complex was made using solvent evaporation method with molar ratio variations of 1: 1, 1: 2, 1: 3, 1: 4 and 1: 5. The results of the inclusion complex were characterized by X-ray diffraction, FTIR, SEM, and DTA. The solubility test was carried out using three different media; they are pH solution 7.4; pH solution 1.5; and distilled water. The solubility test results showed no increase on the ibuprofen solubility of the inclusion complex within medium solutions of pH 7.4 and pH 1.5 whereas in aquades medium there was an increase in the inclusion complex solubility compared to pure ibuprofen. Based on the results, it can be concluded that inclusion complex with molar ratio of 1: 1 shows optimal amount of dissolved ibuprofen compared to other ratio variations in aquadest medium.

Diffusion rate of quercetin from chitosan-TPP nanoparticles dispersion of onion (Allium cepa L.) ethanol extract in medium phosphate buffer pH 7.4 Anisa Amalia; Rahmah Elfiyani; Putri Ulan Sari
Pharmaciana Vol 12, No 1 (2022): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Onion extract contains quercetin, which has anti-inflammatory properties. The absorption of quercetin in the extract can be improved by using the ionic gelation method to composition the extract into a nanoparticle system. Chitosan is a polymer that is used to make nanoparticles that impact medicinal drug absorption. Although many studies of nanoparticle coatings with chitosan have been performed, the effect of the chitosan concentration used remains an intriguing research issue, especially as a natural compound carrier.Â The goal of this study was to examine how varying chitosan polymer concentrations affected the rate of quercetin diffusion from onion (Allium cepa L.) ethanol extract nanoparticles. With 0.1% tripolyphosphate (TPP) as a crosslinker, the concentrations of chitosan used were 0.1% (F1), 0.2% (F2), 0.3% (F3), and 0.4% (F4). Organoleptic test, particle size measurement, zeta potential, polydisperse index, entrapment efficiency, density, and determination of quercetin diffusion rate using a phosphate buffer medium pH 7.4 were all used to analyze each composition. Transparent yellow nanoparticles with particle sizes ranging from 199.89 nm to 514.97 nm, a zeta potential of 47.73 mV to 51.36 mV, a polydispersity index of 0.57, an entrapment efficiency of 54.78 % to 59.06 %, and a density of 1.012 g/mL to 1.042 g/mL are the result of this system. In each composition, the rate of diffusion follows the Higuchi reaction kinetics. Increased chitosan concentration decreases the diffusion rate of onion ethanol extract nanoparticles (Allium cepa L). The fastest diffusion rate value with requirements-meeting physical properties was obtained in nanoparticle systems containing a 0.1 % chitosan solution.Â

Peningkatan Laju Difusi Allisin dalam Sistem Fitosom Ekstrak Bawang Putih Anisa Amalia; Rahmah Elfiyani; Adesi Chenia
JURNAL ILMU KEFARMASIAN INDONESIA Vol 19 No 1 (2021): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v19i1.842

Garlic (Allium sativum L) contains allicin which has the property of reducing blood sugar levels. In previous studies, methanol extract of garlic can reduce blood sugar levels in mice at a dose of 400 mg/kg BW. Penetration of allicin can be increased by formulating extracts in the phytosome system. In this study, it will be observed the effect of making a phytosome system on the diffusion rate of allicin. Garlic extract phytosome was made using a thin layer hydration method which was then evaluated for its physicochemical properties which included testing of entrapment efficiency, density, particle size, index polydispersity, and zeta potential. Determination of the value of the diffusion rate of allicin in the extract and in the phytosome system was carried out using a modified diffusion cell for 420 minutes. The phytosome system formed has an entrapment efficiency value of 64.8789% with a density of 1.0051 g/mL, the particle size of 270 nm, the zeta potential of -32.55 mV and polydispersion index of 0.571. Diffusion rate testing indicates the diffusion rate of the phytosome system can increase the diffusion rate of allicin when compared to the diffusion rate of allicin in garlic extract.

Stabilitas Fisik Transethosome Kurkumin yang Menggunakan Kombinasi Surfaktan Tween 60 dan Span 60 Yudi Srifiana; Anisa Amalia; Yusnia Yusnia
JURNAL ILMU KEFARMASIAN INDONESIA Vol 18 No 2 (2020): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v18i2.796

Curcumin has low solubility in water and has low stability so that a drug delivery system is needed that can overcome these problems. One delivery system that can be used to overcome these problems is transethosome. Transethosome is composed of several component, one of them is surfactant. Surfactant is a component that can help improve the stability of the transethosome system so that in this study research was conducted on the eff ect of the use of a combination of surfactants (tween 60 and span 60) on the physical stability of transethosome curcumin. In this study used a combination of tween 60 and span 60 with a ratio of 1: 2, 1: 1, 2: 1 at a concentration of 5%. Transethosome formed then characterized include organoleptic, viscosity, particle size and particle size distribution, zeta potential, adsorption effi ciency and pH. Transethosome characteristics were observed for 8 weeks to see the physical stability of the transethosome. The results at week 0 indicate that the transethosome formed a suspension with orange color and smelled of phosphatidylcholine with the highest viscosity in formula 3, has a particle size of 1-1000 nm, polydispersity 0-0.571, has a negative zeta potential value, has an absorption effi ciency above 80 % and pH 8.5-10.0. Physical stability test results show the use of a combination of tween 60 and span 60 with rasio 3:1 (F3) can improve the physical stability of transethosome curcumin.

Preparasi dan Karakterisasi Sediaan Solid Lipid Nanoparticle (SLN) Gliklazid ANISA AMALIA; MAHDI JUFRI; EFFIONORA ANWAR
JURNAL ILMU KEFARMASIAN INDONESIA Vol 13 No 1 (2015): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1864.377 KB)

Solid lipid nanoparticle (SLN) has been proposed as colloidal carriers using solid lipid as matrix material. In this study, gliclazide-loaded solid lipid nanoparticle has been prepared with high shear homogenization and freeze drying method using stearic acid as lipid material, Tween 80 and PEG 400 as surfactant, ethanol as`co-solvent and lactose as cryoprotectant. Characterization was performed on SLN dosage from before and after freeze drying, which includes the analysis of particle size, zeta potential value, morphology analysis and entrapment efficiency of gliclazide. Results indicated gliclazidecan be formulated in SLN dosage form using high shear homogenization and freeze drying method. The morphology study revealed that the prepared SLN were irregular in shape with mean particle size of 878.0 ± 246.3 nm and 745.8 ± 204.0 nm. Zeta potensial values of gliclazide-loaded SLN were found –

PROFIL DIFUSI TRANSETHOSOME KURKUMIN DALAM SEDIAAN GEL YANG MENGGUNAKAN KARBOMER 934 SEBAGAI PEMBENTUK GEL Astri Dian Wulandari; Amelia Novianti; Muhammad Andika; Anisa Amalia
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 1 (2019): September 2019
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (657.023 KB)

Kurkumin merupakan senyawa yang berasal dari tanaman kunyit (Curcuma Longa L.). Kurkumin memiliki banyak khasiat, tetapi kelarutan dan penetrasinya rendah. Oleh karena itu, perlu dibuat dalam sistem transethosome. Penelitian ini bertujuan untuk mengetahui profil difusi transethosome kurkumin secara in vitro menggunakan sel difusi franz. Transethosome kurkumin dibuat dengan metode dingin menggunakan pengaduk magnetik. Selanjutnya, transethosome dibuat sediaan gel dengan menggunakan karbomer 934 sebagai basis gel dengan konsentrasi 0,5%; 0,75%; 1% dan 1,25%. Sediaan gel dibuat dengan mencampurkan transethosome kurkumin kedalam basis gel karbomer. Karbomer dipilih karena menghasilkan gel yang memiliki viskositas yang baik. Evaluasi gel dilakukan dengan beberapa parameter seperti organoleptik, potensial zeta, ukuran partikel, pH, homogenitas, reologi dan profil difusi. Jumlah kumulatif kurkumin yang terdifusi selama 6 jam pada masing-masing formula adalah 1921,76µց, 1662,75µց, 1521,40µց, 1298,28 µg. Berdasarkan hasil difusi formula 1 menunjukan jumlah kumulatif yang besar dengan ukuran partikel 325,4 nm.

The Effect of Olive Oil, VCO, and Corn Oil with Adeps Lanae and Vaselin Alba Variation to Physical Characteristic of Methyl Salicylic Stick Balm Anisa Amalia
JCPS (Journal of Current Pharmaceutical Sciences) Vol 3 No 2 (2020): March 2020
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (281.102 KB)

AbstractThe physical characteristic of stick balm have been affected the consistency and comfortness at the time of used. Components that affected the physical properties of stick balm were components of fats and oils. Fat used were adeps lanae and vaseline alba, as it can prevented the tendency to split up oil. The components of the oil used were the VCO which had saturated fatty acids, olive oil and corn oil which had not saturated fatty acids which could affected the melting point and hardness. Based on the foregoing, the comparison of oil type with variations of adeps lanae and vaseline alba carried out towards the physical characteristic of stick balm methyl salicylate. The purpose of this research was to knew the effect of olive oil, corn oil and VCO with variations of adeps lanae and vaseline alba towards the physical properties of stick blam. Adeps lanae and vaselin alba concentration was 10%. Characterization performed on stick balm which included analysis of organoleptics, the melting point and hardness. Results indicate formula with adeps lanae more colored yellow. Homogeneity test of each formula showed that the stick balm was homogeneous. On the hardness and melting point assay, the results qualified on 3.3 mm - 4.16 mm and 51.25 0C - 56.52 0C. A summary of this research was the used of adeps lanae with VCO delivered the highest melting point on 56.52 ºC and the most violent both with translucent 3.33 mm depth. Keywords: physical characteristic, stick balm, a type of oil, variations of adeps lanae and vaseline alba

PENDAMPINGAN PEMBUATAN PANGAN FUNGSIONAL TEH KASKARA KEPADA POKTAN SUKATANI DESA SUKAWANGI BOGOR Nining Nining; Yeni Yeni; Fith Khaira Nursal; Anisa Amalia
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 4 (2022)
Publisher : Universitas Majalengka

Sukatani is a farmer group in Sukawangi Village, Sukamakmur District, Bogor Regency, that requires assistance processing coffee peels. So far, coffee post-harvest technology has only focused on the fruit, while the peel, known as cascara, has been limited to animal feed or even thrown away. Cascara contains antioxidants, phenolic compounds and caffeine, which can potentially be used as a functional food for tea materials. Tea consumption is considered part of a balanced diet, enhancing the antioxidant and overall health status. Cascara processing can be an additional income for farmers, so applying appropriate technology to cascara is necessary. This service activity aims to design tea production using cascara and to diversify coffee products. Cascara is made into dried simplicia and powdered, then packaged in tea bags. This activity is carried out with the direct training tutoring method so that the response or target feedback can be obtained spontaneously and quickly. Activities evaluation is carried out to measure knowledge and achievement success. Statistically, there was an increase in the average score from the pretest (40.36) to the posttest (52.21) with a Sig. (2-tailed) 0.003 (< 0.05) using paired t-test. Thus, the evaluation results show a significant increase in knowledge of the activity target.

Potensi Limbah Kulit Biji Kopi dan Pemanfaatannya sebagai Produk Sabun Cair yang memiliki Aktivitas Antioksidan dan Antibakteri: Potential of Coffee Bean Peel Residue and Its Use in a Liquid Soap with Antioxidant and Antibacterial Fith Khaira Nursal; Anisa Amalia; Supandi Supandi; Nining Nining; Yeni Yeni
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 7 No. 6 (2022): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v7i6.4030

Numerous coffee plantation workers are members of the Neglasari village farmer group, located in Sukawangi village, Bogor district. The problem frequently raised is coffee bean residue, which is typically discarded and provides an idea for the group to consider using it. This issue can be remedied by providing knowledge and direction regarding possible coffee bean husk residues. According to earlier studies, coffee bean skin includes polyphenols with potential antibacterial and antioxidant properties, allowing it to be formulated into skin-safe liquid soap solutions. Participants are productive-age men and female farmers with a constant motivation for entrepreneurship. Participants were provided with a direct explanation of the possibilities of coffee bean husk residue, followed by a short training on manufacturing liquid soap. Comparing the outcomes of the pre-test and post-test provided to participants is an indication of the activity's efficacy. Based on the collected results, it can conclude that the participant's comprehension of the presented material increased significantly (p < 0.05). It anticipated that the outcomes of this product development education and training would enable Farmer Group members to become home-based entrepreneurs.

SIFAT FISIKOKIMIA DAN LAJU DIFUSI PATCH TRANSDERMAL DISPERSI PADAT MELOKSIKAM YANG MENGGUNAKAN NATRIUM LAURIL SULFAT SEBAGAI PENINGKAT PENETRASI Anisa Amalia; Nining Nining; Jannatu Yasmin Adiningsih
Jurnal Farmasi Udayana Vol. 11, No. 2, Tahun 2022
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2022.v11.i02.p01

Meloxicam is a non-steroidal anti-inflammatory medicine (NSAID) with gastrointestinal side effects, hence it's used in transdermal patch preparations as a substitute. Meloxicam was dispersed in PEG 6000 (1:8) and formed as a transdermal patch using sodium lauryl sulfate as a penetration enhancer in this study. The purpose of this study is to see how sodium lauryl sulfate, used as a penetration enhancer, affects the physicochemical characteristics and diffusion of meloxicam in solid dispersion transdermal patches. The patch comes in four different formulas, each with a different concentration of sodium lauryl sulfate: 0% (F0), 1% (F1), 3% (F2), and 5% (F3). The physicochemical parameters of each formula were evaluated, including organoleptic tests, pH, thickness, weight uniformity, moisture content, and folding resistance, as well as diffusion tests. Each formula's transdermal patch has physicochemical characteristics that fulfill the literature's standards. The percentage of meloxicam diffused in each formula was 80.6683 percent, 85.8091 percent, 90.7508 percent, and 93.3322 percent, respectively, with each formula's diffusion rate kinetics following Higuchi's kinetics. The physicochemical characteristics and diffusion rate of the meloxicam transdermal patch were altered by sodium lauryl sulfate (p < 0.05). The most promising patch as an alternative to meloxicam dosage form is meloxicam solid dispersion transdermal patch formulation with 5% sodium lauryl sulfate content.

Co-Authors Abdurrahman, Ade Irfan Adesi Chenia Adia Putra Wirman Alvin Integra Amelia Novianti Amelia Novianti Apt. Fahjar Prisiska Ari Widayanti Astri Dian Wulandari Dewi, Elvira Ratna Dinaianti, Adelia Edi Setiawan Effionora Anwar Etin Diah Permanasari Etnis, Baktianita Ratna Faizal Ridwan Zamzany Fatmawati, Sofia Fith Khaira Nursal Gantini, Sri Nevi Hadi Sunaryo Haqqoni, Muhammad Najmi Hariyanti Hariyanti Hariyanti Hariyanti Hasan Bisri Hukom, Evi Hudriyah Husni, Aisyah Nur Ikeu Ekayanti Irfandi Rahman Jannatu Yasmin Adiningsih Karsiti Karsiti Khairil Anam, Khairil Khalbu, M. Abdullah Khaulah, Khaulah Kriana Efendi Larasati, Kinanti Dara Laszairina, Andra Yunita Mahdi Jufri Muhammad Andika Munatunnisa, Husna Nandhary Fitriana Priyoni Nasution, Zuraidah Nining Nining Nining Nining, Nining Nugrahaeni, Fitria Oktafiani, Erna Palensia, Fadhilah Pratama, Rizal Abdi Putri Ulan Sari Putri, Dania Athaya Rahmah Elfiyani Rahmah Elfiyani Rahmah Elfiyani Rahmatullah, Rizki Riyanto, Raditya Naufal Saputri, Niken Widya Supandi Tahyatul Bariroh Tania, Cici Wahyuni Maria Prasetyo Hutomo Wansit, Aulya Putri Widyaningsih, Sekar Yeni Yeni Yeni Yeni Yeni Yeni Yudi Srifiana Yusnia Yusnia

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