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All Journal Pharmaciana: Jurnal Kefarmasian MANAJEMEN Malahayati International Journal of Nursing and Health Science
Dewi Indah Sari
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Computer Science & IT Economics, Econometrics & Finance Health Professions Medicine & Pharmacology Nursing Public Health Other

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PENINGKATAN SISTEM IMUN OLEH KOMBINASI EKSTRAK ETANOL DAUN AWAR – AWAR (Ficus septica burm. F) DAN EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) SEBAGAI KO-KEMOTERAPI KANKER PADA TIKUS PUTIH BETINA GALUR SPRAGUE DAWLEY YANG DIINDUKSI DOKSORUBISIN Rizka Angerti Anovia; Dewi Indah Sari; Annisa Hardikasari Yazin; Ulfa Ismayani; Endang Darmawan
Pharmaciana Vol 5, No 2 (2015): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2663.276 KB) | DOI: 10.12928/pharmaciana.v5i2.2145

Abstract

Use of the drug doxorubicin for cancer therapy causes decreasing of immune system reported. Leaves of Ficus septica Burm. F and leaves of Moringa oleifera as immunostimulatory agents. The purpose of this study, among others, determine the combined effects of ethanol extract of Ficus septica Burm. F leaves and ethanol extract of Moringa oleifera leaves as co-chemotherapy for in female rats Sprague Dawley strain induced doxorubicin. Eighteen Sprague Dawley rats were divided into six treatment groups, normal group was given 0.9% NaCl 10ml / kgBB, positive control group were given by doxorubicin with dose of 4.67 mg / kgBB, single-dose treatment group were each given ethanol extract of Ficus septica Burm F leaves dose of 750 mg / kgBB and ethanol extract of Moringa oleifera leaves 500 mg / kgBB, treatment groups were given by combination of ethanol extract Ficus septica Burm. F leaves and Moringa oleifera leaves with a dose of 1.25 g / kgBB and a dose of 1 , 75 g / kgBB. treatment carried out for 7 days. On days 1 and 4 of each treatment groups except the normal group induced by doxorubicin 4.67 mg / kgBB intramuscularly. Blood sampling performed on day 0 and 7 th for lymphocytes CD3+ and lymphocytes CD8+ test. The results showed that the combination of ethanol extract Ficus septica burm. F leaves and Moringa oleifera leaves dose of 1.25 g / kgBB and the dose of 1.75 g / kgBB can enhanched immune system relative small which was not statistically significantly different (p> 0.05). However, a single dose of ethanol extract Moringa oleifera leaves dose of 500 mg/kg have immunostimulatory activity as lymphocytes CD3+ and lymphocytes CD8+ were more effective than a single dose of ethanol extract of Ficus septica Burm. F leaves dose of 750 mg/kgBB.
PENGARUH UPAH MINIMUM KOTA, PENDAPATAN PER KAPITA, PENDIDIKAN, DAN KESEHATAN TERHADAP TINGKAT PARTISIPASI ANGKATAN KERJA: (STUDI KASUS : PERKOTAAN DI PROVINSI ACEH) Dewi Indah Sari; Ferayanti Ferayanti; Sri Sukma Wahyuni
MANAJEMEN Vol. 5 No. 2 (2025): Oktober : MANAJEMEN (Jurnal Ilmiah Manajemen dan Kewirausahaan)
Publisher : LPPM Politeknik Pratama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51903/50s9kq67

Abstract

This study aims to analyze the impact of the variables of City Minimum Wage, Per Capita Income, Education Level, and Health on the Labor Force Participation Rate in urban areas of Aceh Province. A quantitative approach using panel data is applied in this research, where secondary data is collected from various official sources such as the Department of Manpower, Population Mobility, and the Central Statistics Agency of Aceh Province, covering the period from 2015 to 2024 in five major cities in Aceh. The analyzed variables include City Minimum Wage, Per Capita Income, Average Length of Schooling, and Life Expectancy. The results of this study show that Per Capita Income and City Minimum Wage have a significant positive effect on labor force participation, but not Years of Schooling and Life Expectancy. The results of this study have important implications for policy makers in the design of effective labor and social development policies to increase labor participation in the region. This research is expected to serve as a foundation for the development of labor economics theory and the formulation of sustainable labor development programs in Aceh Province.
Effectiveness of complementary food formulated from soybean seed coat and milkfish flour in supporting weight gain among young children Lindawati; Sari, Yunita; Sari, Cucuk Kunang; Wijanarko, Bangun; Dewi Indah Sari
Malahayati International Journal of Nursing and Health Science Vol. 9 No. 1 (2026): Volume 9 Number 1
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/minh.v9i1.2027

Abstract

Background: Child undernutrition remains a significant concern in Indonesia, particularly during the complementary feeding period when inadequate dietary quality may impair optimal growth. Purpose: To evaluate the short-term effectiveness of a complementary feeding formulation composed of soybean seed coat flour and milkfish flour in supporting weight gain among children aged 9–12 months. Method: A quasi-experimental one-group pretest–posttest design was conducted among 20 children, with 16 included in the final analysis after excluding dropouts and outliers. Participants received 125 ml of the formulated complementary food daily for nine consecutive days. Body weight was assessed before and after the intervention. Results: Due to non-normal data distribution (Shapiro–Wilk p < 0.05), the Wilcoxon Signed Rank Test was applied. Seven children demonstrated weight gain, seven showed no change, and two experienced slight weight loss. Despite positive tendencies, the overall change was not statistically significant (Z = −1.727; p = 0.08). Factors such as short intervention duration, inconsistent caregiver adherence, concurrent intake of ultra-processed foods, and minor illnesses likely contributed to limited measurable changes. Conclusion: Although not statistically significant, the nutrient-rich formulation shows potential for longer-term application, especially in low-resource settings. Extended duration studies with larger sample sizes are recommended.
Co-Authors Annisa Hardikasari Yazin Endang Darmawan Ferayanti Ferayanti LINDAWATI Rizka Angerti Anovia Sari, Cucuk Kunang Sri Sukma Wahyuni Ulfa Ismayani Wijanarko, Bangun Yunita Sari