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PENINGKATAN SISTEM IMUN OLEH KOMBINASI EKSTRAK ETANOL DAUN AWAR – AWAR (Ficus septica burm. F) DAN EKSTRAK ETANOL DAUN KELOR (Moringa oleifera) SEBAGAI KO-KEMOTERAPI KANKER PADA TIKUS PUTIH BETINA GALUR SPRAGUE DAWLEY YANG DIINDUKSI DOKSORUBISIN Rizka Angerti Anovia; Dewi Indah Sari; Annisa Hardikasari Yazin; Ulfa Ismayani; Endang Darmawan
Pharmaciana Vol 5, No 2 (2015): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2663.276 KB) | DOI: 10.12928/pharmaciana.v5i2.2145

Abstract

Use of the drug doxorubicin for cancer therapy causes decreasing of immune system reported. Leaves of Ficus septica Burm. F and leaves of Moringa oleifera as immunostimulatory agents. The purpose of this study, among others, determine the combined effects of ethanol extract of Ficus septica Burm. F leaves and ethanol extract of Moringa oleifera leaves as co-chemotherapy for in female rats Sprague Dawley strain induced doxorubicin. Eighteen Sprague Dawley rats were divided into six treatment groups, normal group was given 0.9% NaCl 10ml / kgBB, positive control group were given by doxorubicin with dose of 4.67 mg / kgBB, single-dose treatment group were each given ethanol extract of Ficus septica Burm F leaves dose of 750 mg / kgBB and ethanol extract of Moringa oleifera leaves 500 mg / kgBB, treatment groups were given by combination of ethanol extract Ficus septica Burm. F leaves and Moringa oleifera leaves with a dose of 1.25 g / kgBB and a dose of 1 , 75 g / kgBB. treatment carried out for 7 days. On days 1 and 4 of each treatment groups except the normal group induced by doxorubicin 4.67 mg / kgBB intramuscularly. Blood sampling performed on day 0 and 7 th for lymphocytes CD3+ and lymphocytes CD8+ test. The results showed that the combination of ethanol extract Ficus septica burm. F leaves and Moringa oleifera leaves dose of 1.25 g / kgBB and the dose of 1.75 g / kgBB can enhanched immune system relative small which was not statistically significantly different (p> 0.05). However, a single dose of ethanol extract Moringa oleifera leaves dose of 500 mg/kg have immunostimulatory activity as lymphocytes CD3+ and lymphocytes CD8+ were more effective than a single dose of ethanol extract of Ficus septica Burm. F leaves dose of 750 mg/kgBB.
Pengaruh Konsumsi Dark Chocolate Terhadap Tekanan Darah Ibu Hamil Trimester 3 Dalam Mencegah Pre Eclamps Pada Kehamilan di Wilayah Kerja Puskesmas Kabupaten Lebak Mandala Ninik Wahyuni; Ayi Tansah Rohaeti; Dewi Indah Sari
Journal of Midwifery and Health Research Vol 1 No 1 (2022): Journal of Midwifery and Health Research
Publisher : Politeknik Kesehatan Kementerian Kesehatan Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.408 KB) | DOI: 10.36743/jmhr.v1i1.415

Abstract

Hipertensi dalam kehamilan merupakan kondisi medis yang sering terjadi selama kehamilan dan dapat menimbulkan komplikasi pada 2-3 kehamilan, morbiditas/nyeri ibu termasuk kejang eklampsia, hemoragi otak, gagal ginjal akut, dan pembekuan darah pada pembuluh darah serta morbiditas janin (termasuk keterlambatan pertumbuhan janin dalam kandungan, kematian janin dalam kandungan). Salah satu cara untuk mencegah preeklampsia adalah dengan mengonsumsi dark chocolate. Cokelat hitam merupakan cokelat yang memiliki banyak efek kardiovaskular karena mengandung flavonoid dan teobromin yang tinggi. Tujuan: Menganalisis pengaruh konsumsi dark chocolate terhadap tekanan darah ibu hamil trimester III dalam mencegah terjadinya pre-eklampsia dengan metode penelitian. Jenis penelitian ini menggunakan desain penelitian Quasy Eksperimental dengan desain pre-test post-test without control. Jumlah sampel adalah 53 ibu hamil. Analisis univariat menggunakan uji distribusi frekuensi, analisis bivariat menggunakan uji T independen 1 sampel. Hasil penelitian. Setelah dilakukan intervensi didapatkan p-value tekanan darah sistolik 0,000 (p<0,05) dan p-value tekanan darah diastolik 0,000 (p<0,05), artinya ada perbedaan tekanan darah sistolik dan diastolik. Konsumsi coklat hitam (Dark chocolate) berpengaruh terhadap penurunan tekanan darah pada ibu hamil trimester III.
PENGARUH UPAH MINIMUM KOTA, PENDAPATAN PER KAPITA, PENDIDIKAN, DAN KESEHATAN TERHADAP TINGKAT PARTISIPASI ANGKATAN KERJA: (STUDI KASUS : PERKOTAAN DI PROVINSI ACEH) Dewi Indah Sari; Ferayanti Ferayanti; Sri Sukma Wahyuni
MANAJEMEN Vol. 5 No. 2 (2025): Oktober : MANAJEMEN (Jurnal Ilmiah Manajemen dan Kewirausahaan)
Publisher : LPPM Politeknik Pratama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51903/50s9kq67

Abstract

This study aims to analyze the impact of the variables of City Minimum Wage, Per Capita Income, Education Level, and Health on the Labor Force Participation Rate in urban areas of Aceh Province. A quantitative approach using panel data is applied in this research, where secondary data is collected from various official sources such as the Department of Manpower, Population Mobility, and the Central Statistics Agency of Aceh Province, covering the period from 2015 to 2024 in five major cities in Aceh. The analyzed variables include City Minimum Wage, Per Capita Income, Average Length of Schooling, and Life Expectancy. The results of this study show that Per Capita Income and City Minimum Wage have a significant positive effect on labor force participation, but not Years of Schooling and Life Expectancy. The results of this study have important implications for policy makers in the design of effective labor and social development policies to increase labor participation in the region. This research is expected to serve as a foundation for the development of labor economics theory and the formulation of sustainable labor development programs in Aceh Province.