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Correlation of diuretic therapy toward clinicaloutcomeof patients suffering from chronic kidney disease hospitalized in RSUP DR. M. Djamil Padang Fathnur Sani K.; Armenia Nazar; Aina Fatkhil Haque
Pharmaciana Vol 8, No 1 (2018): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2084.892 KB) | DOI: 10.12928/pharmaciana.v8i1.7144

Abstract

ABSTRACTKidney is one of the most important organs of the human body. The goal of diuretic therapy is to reduce edema in patients with impaired renal function. The therapy of diuretic is very important, because the therapy is effective to control of the volume of extracellular fluid, reduce protein exretion in urine and reduce on effects of hyperceluler complications. The purpose of this research is to provide information on the effect of giving diuretics with clinical outcome of patient with cronic kidney disease. The research was conducted by using longitudinal observational study design. Longitudinal observation is a method that perform data retrieval by a prospective census method with daily follow up until patient returns. The result of research showed that the most widely used diuretic was furosemide. Then the results also showed improvement of blood pressure, pulse, respiration rate, creatinine and urea although the results were not statistically significally (p>0.05). Mortality rate of the subjects in RSUP DR. M.Djamil Padang Hospital was very small. Patient with diuretic and without diuretic have equal mortality rate (p>0.05).Keyword: Kidney, CKD, Outcome, Diuretic
FORMULASI DAN UJI IRITASI KRIM M/A DARI EKSTRAK ETANOL BERAS HITAM (Oryza sativa L. indica) Aina Fatkhil Haque; Dewi Winni Fauziah; Nelsie Sopya Dayanie
Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Vol. 5 No. 1 (2019): JURNAL PENELITIAN DAN KAJIAN ILMIAH KESEHATAN POLITEKNIK MEDICA FARMA HUSADA MA
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (542.367 KB) | DOI: 10.33651/jpkik.v5i1.21

Abstract

Black rice (Oryza sativa L. Indica) contains antioxidants which function to reduce fine lines on the face so that it can help neutralize free radicals that cause aging on the skin. Research on black rice extract as an active substance was obtained by maceration method using ethanol solvent 70% and made O/W cream preparations varied with 3 formulas, namely 2%, 4%, and 8%. The physical properties of the cream were tested, namely organoleptic test, homogeneity test, pH test, dispersion test, viscosity test, cream type test, hedonic test, irritation test. The evaluation results of this study are that each concentration of black rice extract can affect the physical properties of O/W Cream
Uji Efektivitas Antibakteri Handsanitizer Minyak Atsiri Kalamansi (Citrofortunella Microcarpa) Terhadap pertumbuhan Escherichia coli dan Staphyllococcus Aureus Secara In Vitro Aina Fatkhil Haque; Betna Dewi; Dika Amanda
Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Vol. 7 No. 1 (2021): JURNAL PENELITIAN DAN KAJIAN ILMIAH KESEHATAN POLITEKNIK MEDICA FARMA HUSADA MA
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (491.781 KB) | DOI: 10.33651/jpkik.v7i1.230

Abstract

This study aims to determine the antibacterial activity, effective concentration, and the effect of increasing the concentration of Kalamansi orange essential oil in Handsanitizer gel on the inhibition of growth of Eschericia coli and Staphyllococus Aureus bacteria. Testing for antibacterial activity using the agar cakram method. The parameter that is measured is the diameter of the resistivity formed around the disc paper. Antibacterial activity test results were analyzed by descriptive method. The results showed that the concentration of essential oil in the Handsanitizer gel was 1%; 2%; and 4% have provided inhibitory activity for the growth of the tested bacteria. Effective concentration that can inhibit Eschericia coli and Staphyllococus Aureus bacteria at a concentration of 4%. The increase in the concentration of kalamansi orange essential oil showed the wider the diameter of the inhibition zone for bacterial growth. The inhibition that occurs in the Eschericia coli and Staphyllococus Aureus bacteria, proves that the Gel Handsanitizer Preparation Kalamansi orange essential oil contains limonene active compounds which are antibacterial. From the research that has been done, the following conclusions can be drawn: The availability of Kalamansi orange essential oil gel Handsanitizer with a concentration of 1%, 2% and 4% can inhibit the activity of the bacteria Eschericia coli and Staphyllococus Aureus in vitro. With the higher the concentration of kalamansi orange essential oil, the stronger the antibacterial inhibition is produced so that the handsanitizer with a concentration of 4% has the strongest antibacterial power against Eschericia coli and Staphyllococus Aureus bacteria.