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All Journal Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Biologi Tropis ad-Dawaa : Journal of Pharmaceutical Sciences SPIN: Jurnal Kimia & Pendidikan Kimia INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Katalisator Jurnal Sains dan Kesehatan
Wahida Hajrin
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Peningkatan Pengetahuan Masyarakat melalui Pelatihan Pengolahan Jahe Merah menjadi Chew Gummy di Desa Senggigi Wahida Hajrin; Yohanes Juliantoni; Windah Anugerah Subaidah
Agrokreatif: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 7 No. 1 (2021): Agrokreatif Jurnal Ilmiah Pengabdian Kepada Masyarakat
Publisher : Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agrokreatif.7.1.1-6

Abstract

Red ginger is a beneficial rhizome used to treat sore throats, dry cough, colic, rheumatism, headache, and flatulence. This community service aims to provide knowledge about the benefits of red ginger for health and how to process red ginger to a worth to sell products. The knowledge about the benefits of red ginger for health presented directly and the processing of chew gummy demonstrated in front of the participants. The community service was carried out at the Senggigi Village Office by involving by involving cadre of Posyandu and PKK asparticipants. The participants are given a pre-test and post-test to determine the increase in participant understanding. The results showed an increase in post-test scores from pre-test values about the benefits of red ginger and its processing. Participants understand the benefits of red ginger for health and can process red ginger into chew gummy preparations.
ANALISIS KANDUNGAN HIDROKUINON DALAM KRIM PEMUTIH YANG BEREDAR DI BEBERAPA PASAR KOTA MATARAM DENGAN SPEKTROFOTOMETRI ULTRAVIOLET-VISIBEL Syarah Megianti Fahira; Agus Dwi Ananto; Wahida Hajrin
SPIN JURNAL KIMIA & PENDIDIKAN KIMIA Vol. 3 No. 1 (2021): Januari - Juni 2021
Publisher : UIN Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/spin.v3i1.3299

Abstract

Hidrokuinon merupakan senyawa turunan benzena yang dapat menghambat produksi melanin sehingga mengurangi pigmentasi pada kulit dan mengatasi hiperpigmentasi serta digunakan sebagai pewarna kuku dan rambut. Namun penggunaan senyawa ini pada kulit dapat menyebabkan efek samping seperti iritasi, vitiligo, okrosisis endogen, kulit menghitam secara permanen bahkan kanker kulit. Tujuan dari penelitian ini adalah mengetahui dan menentukan kadar hidrokuinon dalam krim pemutih yang beredar di Kota Mataram menggunakan spektrofotometri ultraviolet-visibel. Metode yang digunakan pada penelitian ini secara kualitatif menggunakan pereaksi FeCl3, sedangkan secara kuantitatif menggunakan metode spektrofotometri ultraviolet-visible. Hasil penelitian menunjukan bahwa dari 10 sampel terdapat 8 sampel yang positif mengandung hidrokuinon dengan kadar yaitu sampel B 3,438%, sampel C 3,130%, sampel D 3,594%, sampel E 4,156%, sampel F 4,096%, sampel H 4,292%, sampel I 4,086%, sampel J 4,184%. Nilai presisi yang diperoleh sebesar 0,91%, nilai koefisien korelasi (r2) sebesar 0,998, nilai LOD 0,328 ppm dan nilai LOQ sebesar 1,095 ppm. Dapat disimpulkan bahwa kadar hidrokuinon 8 sampel krim pemutih tidak memenuhi persyaratan yang diperbolehkan BPOM yaitu sebesar 0%.
Ethnobotanical Study of Medicinal Plants Used to Treat Degenerative Disease in East Lombok Dyke Gita Wirasisya; Nisa Isneni Hanifa; Wahida Hajrin
Jurnal Biologi Tropis Vol. 20 No. 3 (2020): September - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v20i3.2119

Abstract

Degenerative diseases have become a complex problem around the world. Until now, degenerative diseases have become the biggest cause of death in the world. Approximately, 17 million people die early each year due to the global epidemic of degenerative diseases. Peoples in developing countries still rely on medicinal plants for primary health care. The knowledge for medicinal plant were passed down through generation with little written documentation. This study aimed to document the indigenous medicinal plants used for the treatment for degenerative diseases in East Lombok, Indonesia and to find leads on prospective plants for further ethnopharmacology research based on quantitative ethnobotany index. The ethnomedicinal data were collected through interview and discussion among local healers and plant collected with the help of local guide also herbarium was made to aid specimen confirmation. Ethnomedicinal data was analyzed using use value (UV) along with fidelity level (FL). A total of 20 informants (traditional healers) were interviewed and from the study we can documented the use of 63 plants for the treatment of degenerative diseases. The UV ranged from 0,05 (Sesbania grandiflora) to 0,35 (Carica papaya), while the highest FL (100%) was found for 29 species. Based on the ethnobotanical index (UV and FL) from each plant we can recommend 15 species for further ethnopharmacological study to determine their therapeutic effects and mechanism of action. This study revealed rich ethnomedicinal knowledge from the community in East Lombok for the treatment of degenerative disease. 
Nanoparticle Formula Optimization of Juwet Seeds Extract (Syzygium cumini) using Simplex Lattice Design Method Yohanes Juliantoni; Wahida Hajrin; Windah Anugrah Subaidah
Jurnal Biologi Tropis Vol. 20 No. 3 (2020): September - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v20i3.2124

Abstract

Diabetes is a degenerative disease whose numbers continue to increase from year to year. Treatment with oral antidiabetic drugs can cause harmful side effects for patients. One of the plants that can be used for diabetes therapy is juwet (Syzygium cumini L.). Flavonoid compounds of juwet seed is easily oxidized and hydrolyzed in intestinal fluids with low absorption. This problem can be overcome by forming nanoparticle of juwet seed extract. The aims of this study was to obtain the formula for juwet seed nanoparticles. Nanoparticle of juwet seed extract made by ionic gelation method with chitosan and Na-TPP polymers which are varied. The formula optimization design in this study was determined using a simplex lattice design by 3 variations of materials based on the parameters %entrapment efficiency, %transmittant, particle size, polydisperse index, and zeta potential. The results showed that the yield of duwet seed extract was 7,44%. Juwet seed ethanolic extract contains 3.33 mg of quercetin per 1 g of extract. Based on the desirability value approach, the optimum formula was produced with an extract composition of 1.650 mL; chitosan 0.500 mL; and Na-TPP 0.010 mL can give optimal results with a desirability value of 0.772 which results in the criteria of 63.66% entrapment efficiency; 50.56% transmittant; 615,833nm particle size; 0.620 PDI; and zeta potential of +13.89 mV. Juwet seeds extract can be formulated into the form of nanoparticles. To get better parameters, it is advisable to optimize the mixing time and mixing speed in the ionic gelation method.
Application of Simplex Lattice Design Method on The Optimisation of Deodorant Roll-on Formula of Ashitaba (Angelica keiskei) Wahida Hajrin; Windah Anugrah Subaidah; Yohanes Juliantoni; Dyke Gita Wirasisya
Jurnal Biologi Tropis Vol. 21 No. 2 (2021): Mei - Agustus
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v21i2.2717

Abstract

Ashitaba is known to have antioxidant activity and gram-positive antibacterial activity that causes body odor. This is the potential activity for an active substance to be developed as deodorant. The appropriate formula is needed, so it is necessary to optimize the formula using the right method. This study aimed was to determine the application of the simplex lattice design method on the optimization of a deodorant roll-on formula of ashitaba extract. Ashitaba was extracted by the maceration method. The formula optimization design was determined using the simplex lattice design method by Design Expert®7.5.1. The components for optimization were the concentration of carbopol and concentration of TEA, and the optimization parameters were the spreadability test, sticky power, and pH test. The optimum formula of deodorant consists of 0.45% carbopol and 2.05% TEA. The responses of optimum formula obtained spreadability test 6.32 ± 0.33 cm, sticky power 44.67 ± 3.94 seconds, and pH 7.73 ± 0.17. These results meet the criteria for good preparation but need further testing related to the effectiveness of the preparation and the level of acceptance of the preparation by the user.
PERBANDINGAN FENOLIK TOTAL PADA EKSTRAK BIJI BUAH WALI (BRUCEA JAVANICA L. MERR) DENGAN METODE EKSTRAKSI MASERASI DAN SONIKASI Baiq Rizkia Dwiyana Meliandari; Wahida Hajrin
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 5 No 1 (2022)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v5i1.29317

Abstract

Wali Fruit Seed (Brucea javanica L. Merr) is one of the traditional medicines in Indonesia that has acted as an antidiabetic, antioxidant, and anti-inflammatory. Phenolic compounds play a role in acting as a drug. The amount of phenolic can be influenced by the extraction method used. The purpose of this study was to compare the total phenolic content of wali fruit seed extract with maceration and sonication extraction methods. The advantage of maceration was the simplest and most economical method, while sonication had a short extraction time. The method of this research is the extraction process by maceration and sonication. Screening of phenolic compounds with FeCl3 reagent and determination of total phenolics by the Folin-Ciocalteau method. The results obtained were the total phenolic value with the maceration method was 61,1927±0,1560 mg GAE/g extract, while the total phenolic value with the sonication method was 67,9854±0,0968 mg GAE/g extract. This value was significantly different (p<0.05) statistically. Thus, it was found that the total phenolic by the sonication method was greater than the maceration method. KEYWORDS: wali seeds, maceration, sonication, phenolic
NANOEMULSION EXTRACT ETHANOL Brucea javanica (L) Merr. FORMULATION USING TWEEN 20 & TWEEN 80 AS EMULGATOR Windah Anugrah Subaidah; Wahida Hajrin; Eskarani Tri Pratiwi; Sucilawaty Ridwan
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (196.255 KB) | DOI: 10.62769/katalisator.v8i1.1923

Abstract

Brucea javanica (L) Merr. has the potential to be developed as a topical application as a result of its high flavonoid content. However, advancements in pharmaceutical preparation are constrained by the chemicals' poor bioavailability when prepared conventionally. Nanoemulsion preparation has been an efficient method for enhancing topical preparation absorption. The previous studies show that the stable formulation of nanoemulsion depends on emulgator, especially tween. This study's objective is to create an ethanol extract of Brucea javanica (L) Merr. using tween 20 and tween 80 as emulsifying agent. A pseudo-ternary phase diagram was utilized to formulate the nanoemulsion formula. Physical characteristics such as particle size, polydispersity index, zeta potential, percent transmittance, drug load, viscosity, and pH were then analyzed for the nanoemulsion. At 15 sampling points, the formula tween 20 (surfactant):PEG 400 (cosurfactant) in a 1:1 ratio did not produce a clear preparation. In contrast, tween 80 with the same cosurfactant and ratio formed a formula that was transparent. The formula was then examined for its physical parameters, which included a particle size of 17.90.14 nm, a polydispersity index of 0.0970.012, a zeta potential of 84.63% transmittance, a drug load of 99.97%, a viscosity of 240 cp, and a pH of 7.194. According to the results, tween 80 is the most suited emulsifier for the production of Brucea javanica (L) Merr extract nanoemulsion. The study of physical attributes reveals that the nanoemulsion generated satisfies the criteria for nanoemulsions with desirable physical properties. Furthermore, the study provides data required for the development of a nanoemulsion of ethanol extract of Brucea javanica.
Edukasi penggunaan sediaan tabir surya sebagai upaya pencegah penuaan dini dan kanker kulit di SMAIT Anak Sholeh Mataram Windah Anugrah Subaidah; Wahida Hajrin; Yohanes Juliantoni
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 2 (2023): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v4i2.202

Abstract

Prolonged sun exposures can have negative impacts to skin such as premature aging and skin cancer. These impacts can be minimized by using sunscreen. Unfortunately, majority of Lombok islanders, especially students, still not aware on sunscreen benefits and applications. Therefore, community service is conducted to educate on the danger of prolonged sun exposures on skin and on how to apply sunscreen to prevent skin aging and skin cancer. The method consists of preparation stage, pre-test, education, and evaluation. The community service on SMAIT Anak Sholeh Mataram is considered to be positive by the involved party. This activity has been an early education for the students about how to prevent premature aging and skin cancer. Furthermore, the test result shows there is a positive increase on the training participants’ knowledge.
Determination of Antioxidants by DPPH Scavenging Activity of Ashitaba Herb (Angelica keiskei) Methanol Extract Handa Muliasari; Nisa Isneni Hanifa; Wahida Hajrin; Mahacita Andanalusia; Agriana Rosmalina Hidayati
Jurnal Biologi Tropis Vol. 23 No. 4 (2023): October - December
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4.5686

Abstract

Ashitaba (Angelica keiskei) is one of the plants cultivated in the Sembalun region, Lombok, NTB, which has the potential to be developed as a source of antioxidants. This study aims to determine the antioxidant activity of the methanol extract of ashitaba herb by measuring the inhibition against DPPH (1,1-diphenyl-2-picrylhydrazyl) radicals using a UV-Vis spectrophotometer. Ashitaba herb samples were collected in Jorong Hamlet, Sembalun Bumbung Village, Sembalun District, East Lombok Regency at coordinates 8°23'5.273" LAT - l16°32'12.016" EAST. The sample was then processed into simplisia with a simplisia yield of 14.75%. The simplisia was dechlorinated with n-hexane solvent and then extracted with 80% methanol solvent using the sonic method, giving a methanol extract of ashitaba herb yielding 20.30%. DPPH radical inhibitory activity was measured at a maximum wavelength of 516 nm and an operating time (OT) of 30 minutes. The methanol extract of ashitaba herb has an IC50 value of 129.40 ± 7.36 ppm, which shows moderate antioxidant activity, with a standard compound comparison of ascorbic acid with an IC50 value of 2.37 ± 0.06 ppm, which is classified as very potent.
Formulasi dan Karakterisasi Nanopartikel Kitosan Ekstrak Sari Buah Juwet (Syzygium cumini) menggunakan metode Gelasi Ionik: Formulation and characterization of Chitosan Nanoparticle of Juwet (Syzygium cumini) Fruit Extract Using Ionic Gelation Method Wahida Hajrin; Wayan Cintya Ganes Budastra; Yohanes Juliantoni; Windah Anugrah Subaidah
Jurnal Sains dan Kesehatan Vol. 3 No. 5 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i5.614

Abstract

Syzygium cumini (S. cumini) fruits have a high potential to be developed as medicine because of their polyphenol content. Polyphenol is easily degraded so that its stability needs to be increased through the formation of nanoencapsulation. The aim of this study was to determine the formula of SBJ nanoparticles which has good characteristics. The formula was determined using a pseudoternary phase diagram based on the %transmittant and %EE. Nano SBJ was characterized for % transmittant ,% EE, polydispersity index, and zeta potential. The formula of Nano SBJ obtained chitosan, SBJ extract, and Na TPP were 0.347%, 0.627%, and 0.047%, respectively. The characterization of Nano SBJ were % EE was 30.72%, the mean diameter of particles was 138.1 ± 7.9 nm, PdI was 0.839 ± 0.043, and zeta potential was 34.9 ± 1.2 mV. Nano SBJ has nano-sized particles and has good stability, but low in entrapment efficiency.
Co-Authors Agus Dwi Ananto, Agus Baiq Rizkia Dwiyana Meliandari Dyke Gita Wirasisya Eskarani Tri Pratiwi Handa Muliasari Hidayati, Agriana Rosmalina Mahacita Andanalusia Nisa Isneni Hanifa Sucilawaty Ridwan Syarah Megianti Fahira Wayan Cintya Ganes Budastra Windah Anugerah Subaidah Windah Anugrah Subaidah Yohanes Juliantoni