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Karakteristik Pengetahuan dan Persepsi Penderita Akne Vulgaris di Kota Mataram Hidajat, Dedianto; Hidayati, Agriana Rosmalina; Cenderadewi, Muthia
Jurnal Kedokteran Vol 5 No 4 (2016)
Publisher : Faculty of Medicine Universitas Mataram

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Abstract

Pendahuluan: Beberapa penelitian di negara maju maupun berkembang telah menunjukkan bahwa penderita akne vulgaris (AV) mendapatkan informasi yang inadekuat tentang penyebab dan penanganan AV. Tujuan: Mengetahui karakteristik pengetahuan dan persepsi penderita AV terkait faktor penyebab, sumber informasi, penatalaksanaan dan dampak psikososial AV di kota Mataram Metode: Penelitian ini merupakan survei karakteristik pengetahuan dan persepsi dengan rancangan penelitian deskriptif dengan pendekatan cross sectional. Hasil: Dari 162 responden, 51,2% sudah menderita AV selama lebih dari 1 tahun dan 54,9% termasuk derajat ringan. Sebanyak 30% responden menyatakan bahwa AV disebabkan oleh penyebab tunggal dan jenis penyebab terbanyak adalah karena kurangnya kebersihan wajah (34,8%). Stres (25,3%) merupakan faktor yang paling banyak dianggap berperan dalam memperberat AV. Tiga sumber informasi terbesar terkait AV berasal dari internet (20,9%), televisi/radio (19,9%) dan dokter (17,2%). Harapan responden (55,6%) pengobatan berlangsung dalam waktu kurang dari 2 minggu untuk mengatasi AV. Sebagian besar responden (38,3%) telah mencoba lebih dari 1 jenis produk untuk mengatasi AV sebelum memutuskan untuk berobat ke dokter dan sabun pembersih jerawat merupakan produk yang paling banyak digunakan oleh responden (38,1%). Sebagian besar responden (36,4%) menyatakan bahwa menderita AV memiliki pengaruh yang sangat besar terhadap penampilan. Kesimpulan: masih adanya informasi yang belum adekuat dari sumber yang telah ada terkait penyebab, faktor yang mencetuskan dan penanganan AV.
Karakteristik Pengetahuan dan Persepsi Penderita Akne Vulgaris di Kota Mataram Hidajat, Dedianto; Cenderadewi, Muthia; Hidayati, Agriana Rosmalina
Jurnal Kedokteran Vol 5 No 4 (2016)
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pendahuluan: Beberapa penelitian di negara maju maupun berkembang telah menunjukkan bahwa penderita akne vulgaris (AV) mendapatkan informasi yang inadekuat tentang penyebab dan penanganan AV. Tujuan: Mengetahui karakteristik pengetahuan dan persepsi penderita AV terkait faktor penyebab, sumber informasi, penatalaksanaan dan dampak psikososial AV di kota Mataram Metode: Penelitian ini merupakan survei karakteristik pengetahuan dan persepsi dengan rancangan penelitian deskriptif dengan pendekatan cross sectional. Hasil: Dari 162 responden, 51,2% sudah menderita AV selama lebih dari 1 tahun dan 54,9% termasuk derajat ringan. Sebanyak 30% responden menyatakan bahwa AV disebabkan oleh penyebab tunggal dan jenis penyebab terbanyak adalah karena kurangnya kebersihan wajah (34,8%). Stres (25,3%) merupakan faktor yang paling banyak dianggap berperan dalam memperberat AV. Tiga sumber informasi terbesar terkait AV berasal dari internet (20,9%), televisi/radio (19,9%) dan dokter (17,2%). Harapan responden (55,6%) pengobatan berlangsung dalam waktu kurang dari 2 minggu untuk mengatasi AV. Sebagian besar responden (38,3%) telah mencoba lebih dari 1 jenis produk untuk mengatasi AV sebelum memutuskan untuk berobat ke dokter dan sabun pembersih jerawat merupakan produk yang paling banyak digunakan oleh responden (38,1%). Sebagian besar responden (36,4%) menyatakan bahwa menderita AV memiliki pengaruh yang sangat besar terhadap penampilan. Kesimpulan: masih adanya informasi yang belum adekuat dari sumber yang telah ada terkait penyebab, faktor yang mencetuskan dan penanganan AV. Katakunci
Peningkatan Pengetahuan Studi Etnomedisin Pada Mahasiswa Farmasi Nisa Isneni Hanifa; Agriana Rosmalina Hidayati; Anggit Listyacahyani Sunarwidhi; Dyke Gita Wirasisya
Jurnal Pengabdian Magister Pendidikan IPA Vol 4 No 4 (2021)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (194.01 KB) | DOI: 10.29303/jpmpi.v4i4.1240

Abstract

The topic of research on the exploration of natural materials is still a favorite among pharmacy students. This is also supported by the biodiversity in Indonesia which is spread across the region. Students need more insight and description of research topics related to natural product products, one of which is ethnomedicine studies. Based on this background, it is necessary to provide education related to ethnomedicine studies from experts to increase students' knowledge about the topic of exploring medicinal herbs and plants from ethnic groups in Indonesia. Education is carried out using lecture and discussion methods in webinars using virtual meeting applications with pretest and posttest. The webinar was attended by 239 participants, with the majority being pharmacy students from several Indonesian pharmacy universities. From the results of the pretest, it is known that the average knowledge of participants about ethnomedicine is 53.89. After the expert's explanation, the participants' knowledge increased with the average post-test score of 71.21. Participants' knowledge of the ethnomedicine study increased after being given education.
ALIH INFORMASI TITIK KRITIS HALAL PADA SEDIAAN KOSMETIKA HERBAL Agriana Rosmalina Hidayati; Anggit Listyacahyani Sunarwidhi; Nisa Isneni Hanifa; Neneng Rachmalia Izzatul Mukhlishah; Mahacita Andanalusia
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 4 (2022): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i4.11741

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ABSTRAKSaat ini produk halal telah mampu menjadi primadona yang digunakan beberapa negara untuk meningkatkan devisa, tidak terkecuali di Indonesia. Kosmetika sebagai produk dalam memelihara kecantikan semakin berkembang seiring dengan perkembangan bioteknologi. LPPOM MUI mengungkapkan ada dua titik kritis yang perlu diperhatikan dalam kehalalan produk kosmetik yaitu bahan yang digunakan dan tembus air. Kegiatan pengabdian masyarakat dalam bentuk webinar dan workshop mengenai titik kritis halal pada sediaan kosmetika herbal dilakukan untuk membantu mahasiswa memperoleh informasi dan keterampilan terkait kosmetik halal secara mendalam. Dalam kegiatan webinar, diketahui terjadi peningkatan pengetahuan antara sebelum dan setelah dilakukannya paparan materi (p-value < 0.005). Peserta dengan nilai terbaik selanjutnya mengikuti workshop pembuatan gel anti-acne dengan bahan herbal. Melalui kegiatan pengabdian ini, dapat disimpulkan     bahwa penerapan titik kritis halal pada kosmetik herbal dan formulasi kosmetik herbal halal dapat diimplementasikan untuk pengembangan produk halal di kemudian hari. Kata kunci: edukasi; titik kritis halal; kosmetika herbal; mahasiswa. ABSTRACTHalal products have become the prominance that are used in several countries to increase foreign exchange, including Indonesia. Cosmetic continues to grow along with the development of biotechnology. LPPOM MUI revealed that there are two critical points that need to be considered in the halalness of cosmetic products, such as the materials used and water permeability. Webinar and workshop on halal critical points in herbal cosmetic preparations as community service activity were conducted to help students gain in-depth information and skills related to halal cosmetics. It is known that there is an increase in knowledge between before and after the webinar activity (p-value < 0.005). Participants with the best scores then took part in a workshop on making anti-acne gel with herbal ingredients. Through this service activity, it can be concluded that the application of halal critical points in herbal cosmetics and halal herbal cosmetic formulations can be implemented for the development of halal products in the future. Keywords: education; halal critical point; herbal cosmetics; students.
Anti-Stapylococcus Epidermidis of Methanolic Extracts from Some East Lombok Medicinal Plants Dyke Gita Wirasisya; Amni Hamid; Muhamad Haikhal; Agriana Rosmalina Hidayati; Anggit Listyacahyani Sunarwidhi; Nisa Isneni Hanifa
Jurnal Biologi Tropis Vol. 23 No. 2 (2023): April-June
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i2.4732

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Wounds are structural and functional disruptions of the skin that occur as a result of an injury. Wound healing is a complex tissue repair or remodelling process in response to the injury. The most common factor that causes wounds not properly heal is infection. An infection develops when microorganisms enter the body, multiply, and trigger an immune reaction in the body. This study aims to determine the activity of Jatropha multifida L., Stachytarpheta jamaicensis (L.) Vahl, Centella asiatica (L.) Urb., Euphorbia pulcherrima Willd. ex Klotzsch, and Angelica keiskei (miq.) Koidz has long been used to treat and manage wounds in East Lombok. The plants were dried and macerated with methanol; excessed solvent was evaporated. Disc diffusions were used to determine the antibacterial activity of the plant extracts. All extracts were tested against Staphylococcus epidermidis, a common cause of wound infection. Statistically, the activity of Jatropha multifida (5;10 mg/mL), Stachytarpheta jamaicensis (10 mg/mL), Centella asiatica (10 mg/mL), Euphorbia pulcherrima (M) (5, 10 mg/mL), and Angelica keiskei (2,5; 5; 10 mg/mL) extracts were comparable with positive control. However, Angelica keiskei has a wider inhibition zone than other extracts. This discovery could be served as a basis for using plants to aid wound healing, especially to combat the interference bacteria. However, further research is needed to discover the active phytochemicals involved in the antibacterial and wound healing process.
Teh herbal terstandar simplisia bunga gemitir (Tagetes erecta Linn.) sebagai kandidat antioksidan baru Kadar Riansyah; Aliefman Hakim; Agriana Rosmalina Hidayati
Sasambo Journal of Pharmacy Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i1.194

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Empirically, gemitir flower (Tagetes erecta Linn.) has been used for generations as an alternative to treat whooping cough and eye pain medication. Gemitir flower is potential as an antioxidant because it contains secondary metabolites of phenolic groups, flavonoids, and alkaloids that have been shown to have antioxidant activity. As a pharmaceutical products, medicinal plants must be guaranteed quality and safety. This study aims to determine the suitability of the simplicia quality of gemitir flowers by standardization based on Indonesian Herbal Pharmacopoeia and Indonesian Materia Medica, and also to determine the antioxidant potential of standardized herbal teas of gemitir flowers. This first step of this research were standardization of gemitir flower simplicia based on specific and non-specific parameters, followed by making standardized herbal tea of gemitir flower. Antioxidant activity test was carried out on tea preparations using the DPPH method. The results showed that the simplicia of gemitir flower met all the standard parameters of specific and non-specific standardization with an ash content value of 3,47%, acid insoluble ash content of 0,11%, water soluble extract content of 24,86%, ethanol soluble extract content of 21,67%, drying shrinkage content of 9,33%, moisture content of 9,23% and foreign organic matter of 0,3%. Standardized herbal tea simplicia gemitir flower was able to inhibit 50% of DPPH free radicals at a volume of 33,87 µL. Based on the results, it can be concluded that the empirical use of gemitir flower tea potential as a natural antioxidant.
Formulasi tablet hisap ekstrak etanol daun kemangi (Ocimum sanctum L.) dengan variasi konsentrasi bahan pengikat gelatin Putri Nuryana; Windah Anugrah Subaidah; Agriana Rosmalina Hidayati
Sasambo Journal of Pharmacy Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i1.213

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Basil leaves (Ocimum sanctum L.) contain secondary metabolites as inhibitors of the growth of pathogenic microbes in the mouth, so they can be used as lozenges. The choice of binder in the formulation is very important, because it can affect the physical properties of the tablet. The purpose of this study was to determine the content of secondary metabolites in basil leaf extract and determine the best formula for lozenges of ethanol extract of basil leaves based on variations in gelatin binding agents. Basil leaves were extracted using the sonication method with 96% ethanol solvent and subjected to phytochemical screening (test tube and TLC). Tablets were formulated using the wet granulation method with variations of gelatin in formula 1 (5%), formula 2 (7.5%), and formula 3 (10%). The physical properties of the granules are evaluated and compressed. The resulting tablets were evaluated for physical properties. The results showed that basil leaves contained compounds belonging to the class of flavonoids, saponins and tannins. The results of the granule flow time test for formula 1 and 2 did not meet the requirements, formula 3 met the requirements for the Indonesian Pharmacopoeia Edition III. The angle of repose, settling, and granule water content tests (formula 1, 2, and 3) met the requirements of the Indonesian Pharmacopoeia Edition III. The results of tablet evaluation in the weight uniformity test for formulas 1, 2, and 3 were 257 mg ± 0.226; 248 mg ± 0.068 and 253 mg ± 0.157. Tablet hardness test of 3.721 kg ± 0.268; 4.221 kg ± 0.929 and 6.636 kg ± 1.035. Tablet friability test of 3.4% ± 0.152; 1.1% ± 0.264 and 0.9% ± 0.1. The disintegration time test was 7.6 minutes ± 2.452; 11 minutes ± 2.154 and 18.6 minutes ± 4.016. From this study it can be concluded that the ethanol extract of basil leaves has secondary metabolites of flavonoids, saponins and tannins. Variations in gelatin binder affect the physical properties of the tablet, where the concentration of gelatin binder is best in formula 3 (10%).
Uji aktivitas antimikroba ekstrak etanol buah renggak (Amomum dealbatum Roxb.) terhadap Staphylococcus aureus dan Candida albicans Muhammad Robby Rizky; Agriana Rosmalina Hidayati; Anggit Listyacahyani Sunarwidhi
Sasambo Journal of Pharmacy Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i1.215

Abstract

Staphylococcus aureus and Candida albicans are microorganisms that cause infection in humans and have developed resistance to several classes of antibiotics and antifungals. Plants in the genus Amomum have been used in traditional medicine and have scientific potential as alternatives to natural antibacterial and antifungal agents. Renggak (Amomum dealbatum Roxb.) is a species of the genus Amomum that is commonly found in Lombok. Scientific research related to the antibacterial and antifungal activity of the fruit is still limited. The aim of this study was to determine the antibacterial and antifungal activity of ethanol extract of renggak fruit against Staphylococcus aureus and Candida albicans. The extraction method used sonication with 96% ethanol. Testing of antibacterial and antifungal activity by disc diffusion method. The positive control used chloramphenicol for antibacterial testing and ketoconazole for antifungal testing, while the negative control used 10% DMSO solution. The antibacterial and antifungal activity of the extract was measured based on the diameter of the inhibition zone formed around the disc. Data analysis used the Kruskall-Wallis statistical test with a 95% confidence level. The results showed that the ethanol extract had moderate activity against S. aureus at concentrations of 20% w/v & 30%w/v with inhibitory diameters ranging from 5-7 mm, while at concentrations of 40% w/v & 50% w/v. has strong activity with inhibitory diameters ranging from 10-15 mm. The ethanol extract showed no activity at concentrations of 50%, 75%, and 100% in inhibiting the growth of the fungus C. albicans. Statistical test of each extract concentration had a significant effect on the inhibition of growth of S. aureus compared to the negative control. Based on the description above, it can be concluded that the extract of renggak fruit has the potential to inhibit the growth of S. aureus.
Studi Kelayakan Pendirian Program Studi Profesi Apoteker di Universitas Mataram, Nusa Tenggara Barat Agriana Rosmalina Hidayati; Candra Eka Puspitasari; Anggit L. Sunarwidhi; Siti Rahmatul Aini; Iman Surya Pratama Pratama; Baiq Ihda Nanda Safriyana
JURNAL SOSIAL EKONOMI DAN HUMANIORA Vol. 8 No. 1 (2022): JURNAL SOSIAL EKONOMI DAN HUMANIORA
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (69.393 KB) | DOI: 10.29303/jseh.v8i1.22

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West Nusa Tenggara (NTB) is one of the provinces that does not yet have educational facilities for the Pharmacist Professional Study Program, although it already has several Bachelor of Pharmacy Study Programs, one of which is at the University of Mataram. The pharmacist profession program aims to produce pharmacists who are expected to improve health services in West Nusa Tenggara. However, establishing a study program requires a feasibility analysis of the establishment. This feasibility study research is descriptive in nature using a qualitative design with a case study method, namely by taking pictures and describing an overview of the Pharmacist Professional Study Program feasibility study, Faculty of Medicine, University of Mataram. The instrument for collecting qualitative research data is the researcher as the main instrument equipped with a guide for observations, interviews, and document searches summarized in a Forum Group Discussion (FGD) activity. The results obtained the formation of the curriculum, the establishment of tuition fee, the preparation of a strategic plan which is the result of the process of preparing the management, the arrangement of human resource development methods, and the establishment of a special education facility as well as a computer-based exam room (CBT) and Objective Structured Clinical Examination (OSCE). We can be concluded that the PSPA Mataram University deserves to be established
Uji Aktivitas Antioksidan Kombinasi Ekstrak Kulit Pisang Kepok (Musa paradisiaca L.) dan Kulit Buah Naga Merah (Hylocereus polyrhizus (Weber) Britton & Rose) dengan Metode DPPH Baiq Ridho Amalia; Handa Muliasari; Agriana Rosmalina Hidayati
Jurnal Pharmascience Vol 10, No 1 (2023): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i1.14863

Abstract

Senyawa antioksidan mampu meredam senyawa radikal bebas sehingga menjadi substansi yang tidak berbahaya. Sumber antioksidan dibagi dalam dua kategori, antioksidan sintetis dan alami. Antioksidan alami dapat diperoleh dari bahan alam, salah satunya kulit pisang kepok (Musa paradisiaca L.) dan kulit buah naga merah (Hylocereus polyrhizus (Weber) Britton & Rose). Penelitian ini dilakukan untuk mengetahui aktivitas antioksidan yang dihasilkan ekstrak tunggal kulit buah pisang kepok (KPK) dan kulit naga merah (KNM) serta aktivitas antioksidan kombinasi keduanya. Kombinasi ekstrak KPK dan KNM dibuat dengan rasio (1:1); (1:2); dan (2:1). Ekstrak KPK dan KNM mengandung senyawa flavonoid yang berperan dalam aktivitas antioksidan yang dihasilkan. Uji aktivitas antioksidan dilakukan dengan metode DPPH. Nilai IC50 ekstrak tunggal KPK dan KNM adalah 79,34 ± 1,139 ppm dan 79,96 ± 0,899 ppm. Nilai IC50 Kombinasi ekstrak KPK dan KNM dengan variasi (1:1); (1:2); dan (2:1) adalah 19,50 ± 2,552 ppm; 58,38 ± 2,338 ppm; dan 18,76 ± 1,605 ppm. Uji one way ANOVA menunjukkan nilai IC50 ekstrak tunggal dan kombinasinya berbeda signifikan (p < 0,05). Kombinasi ekstrak KPK dan KNM menghasilkan aktivitas antioksidan yang lebih kuat dibandingkan dengan ekstrak tunggalnya. Kata Kunci: Sonikasi, KLT, Flavonoid, Kombinasi Ekstrak, DPPH Antioxidant compounds can reduce free radical compounds and become harmless substances. Antioxidants are divided into two, which are synthetic and natural antioxidants. Natural antioxidants can be obtained from natural ingredients, such as the peel of kepok banana (Musa paradisiaca L.) and the peel of the red dragon fruit (Hylocereus polyrhizus (Weber) Britton & Rose). The goals of this study are to determine the antioxidant activity of extract kepok banana peel (KPK), red dragon fruit peel (KNM) and extract combination of both. The combination of KPK and KNM extracts was made in a ratio of (1:1); (1:2); and (2:1). KPK and KNM extracts contain flavonoid compounds which are responsible for the antioxidant activity produced. The antioxidant test was carried out using the DPPH method. The IC50 values of the single extracts of KPK and KNM were 79.34 ± 1.139 ppm and 79.96 ± 0.899 ppm. IC50 value combination of KPK and KNM extracts with variation (1:1); (1:2); and (2:1) are 19.50 ± 2.552 ppm; 58.38 ± 2.338 ppm; and 18.76 ± 1.605 ppm. One way ANOVA test showed that the IC50 values of single extracts and their combinations were significantly different (p < 0.05). The combination of KPK and KNM extracts had stronger antioxidant activity than the single extracts.
Co-Authors Abdillah, Lalu Khairi Achmad Fuad Hafid Agustini, Nur Indah Aini, Siti Rahmatul Aliefman Hakim Amira Amira Amni Hamid Anggit L. Sunarwidhi Anggit Listyacahyani Sunarwidhi Anindiya, Naya Wahyu Anisa Febriani Ariani, Fitri Aty Widyawaruyanti Aulia, Dia Ul Avida In Amy Baiq Ihda Nanda Safriyana Baiq Ridho Amalia Bayani, Faizul Cahyani, Dina Fathia Candra Eka Puspitasari Corry, Maylisa Natalia Dedianto Hidajat Dewi Suryani Dia Ul Aulia Djoko Agus Purwanto Dyke Gita Wirasisya Dyke Gita Wirasisya Dyke Gita Wirasisya Edhi, Narendrani Sasmitaning Einstenia Kemalahayati Hafizah, Gina Tasya Rizka Hajrin, Wahida Handa Muliasari Handa Muliasari Hasan, Muhammad Amir Hidayati, Regina Tria Hilkatul Ilmi Ilmi, Hilkatul Iman Surya Pratama Iman Surya Pratama Pratama Indah Permata Sari Indra Purnomo Indriani, Zulfia Ika Julia Harpina Kadar Riansyah Khairatun, Laziza Iklima Kurniasih Sukenti Lahardo, Devanus Lidya Tumewu Lina Permatasari Mahacita Andanalusia Mahacita Andanalusia Marsih Wijayanti Muhamad Haikhal Muhammad Robby Rizky Mukhlishah, Neneng Rachmalia Izzatul Muliasari, Handa Muthia Cenderadewi, Muthia Neneng Rachmalia Izzatul Mukhlishah Nisa Isneni Hanifa NURUL HIDAYAH Permatasari, Lina Permatasari, Ni Made Ayu Dinda Pratama, Iman Surya Pratiwi, Eskarani Tri Prianggawe, Prianggawe Pujiarohman, Pujiarohman Purwitasari, Neny Putri Nuryana Raissa, Talitha Hasna Ramadhan, Muhammad Rafi Bintang Retno Widyowati Riadi, Putri Oktaviati Riesta Primaharinastiti, Riesta Risnata, Richa Poetri rizki, alpa alfi Rizkika, Adila Safriyana, Baiq Ihda Nanda Siti Rahmatul Aini Suciati Suciati Suciati Suciati Sukardiman sulistanti, Erly Sunarwidhi, Anggit Listyacahyani suryani, Bunga Tri Widiandani Wahida Hajrin Wardani, Ray Haerul Wicaksana, Firman Windah Anugrah Subaidah Wirasisya, Dyke Gita Yayuk Andayani Yunita Yunita Zahra, Nisrina