Bismarck J. Laihad
Faculty of Medicine University of Sam Ratulangi/ Prof. Dr. R.D. Kandou General Hospital Manado

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HE4 has a High Diagnostic Value to Detect Epithelial Ovarian Cancer Laihad, Bismarck J.
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.209 KB)

Abstract

Objective: To find out the diagnostic value of CA125 and HE4 as a tumor marker, and also RMI and ROMA as a malignancy predictor in patients with ovarian tumors. Methods: This study was a diagnostic study using cross-sectional design.This study was performed in Jakarta from November 2010 to May 2011. One hundred and twenty eight serum samples of patients diagnosed with ovarian tumors were collected before undergoing surgery in Dr. Cipto Mangunkusumo General Hospital. The CA125 and HE4 levels were then examined. The histopathological examination of tissue specimens were performed in Department of Pathology Anatomy in RSCM. For statistical analysis, we used a 2x2 table to produce ROC-AUC curve. Results: The median value of HE4 and CA125 serum concentrations was higher and more significant on patients with ovarian malignancy than patients with benign ovarian tumor (p
HE4 has a High Diagnostic Value to Detect Epithelial Ovarian Cancer Laihad, Bismarck J.
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.209 KB) | DOI: 10.32771/inajog.v1i4.368

Abstract

Objective: To find out the diagnostic value of CA125 and HE4 as a tumor marker, and also RMI and ROMA as a malignancy predictor in patients with ovarian tumors. Methods: This study was a diagnostic study using cross-sectional design.This study was performed in Jakarta from November 2010 to May 2011. One hundred and twenty eight serum samples of patients diagnosed with ovarian tumors were collected before undergoing surgery in Dr. Cipto Mangunkusumo General Hospital. The CA125 and HE4 levels were then examined. The histopathological examination of tissue specimens were performed in Department of Pathology Anatomy in RSCM. For statistical analysis, we used a 2x2 table to produce ROC-AUC curve. Results: The median value of HE4 and CA125 serum concentrations was higher and more significant on patients with ovarian malignancy than patients with benign ovarian tumor (p
Insiden dan Mortalitas Penderita Kanker Serviks di RSUP Prof. Dr. R. D. Kandou Periode Januari 2014 - September 2015 Mamesah, Frits; Laihad, Bismarck J.; Kaeng, Juneke J.
e-CliniC Vol 6, No 1 (2018): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v6i1.19501

Abstract

Abstract: Cervical cancer is caused by human papiloma virus (HPV). It is a malignant disease in obstetrics and gynecology field which still occupies the highest position cancer among females woman. This study was aimed to obtain the incidence and mortality of cervical cancer patients at Prof. Dr. R. D. Kandou Hospital Manado from january 2014- september 2015. This was a descriptivease retrospective study using patients’ medical record data of cervical cancer. The results showed that there were 121 patients of cervical cancer, most were in the age group of 41-50 years (39.67%) and stage III B (41 people; 33.89%); 23 patients (19.00%) died. Conclusion: The incidence of cervical cancer at Prof. Dr. R. D. Kandou Hospital Manado was high enough with a mortality rate of 19.00%.Keywords: cervical cancer Abstrak: Kanker serviks disebabkan oleh Human Papiloma Virus (HPV) dan merupakan salah satu penyakit keganasan di bidang obstetrik dan ginekologi yang masih menempati posisi tertinggi sebagai penyakit kanker yang menyerang kaum perempuan. Penelitian ini bertujuan untuk mengetahui insiden dan mortalitas pasien kanker serviks di RSUP Prof. Dr. R. D. Kandou Manado sejak Januari 2014-Septemper 2015. Jenis penelitian ialah deskriptif retrospektif dengan menggunakan data rekam medik pasien kanker serviks. Hasil penelitian mendapatkan 121 kasus kanker serviks, terbanyak pada kelompok usia 41-50 tahun (39,67%). Kebanyakan pasien berada pada stadium IIIB sebanyak 41 orang (33,89%) dan 23 penderita (19,00%) dinyatakan meninggal dunia. Simpulan: Insiden penderita kanker serviks di RSUP Prof. Dr. R. D. Kandou Manado cukup tinggi dengan angka mortalitas sebesar 19,00%.Kata kunci: kanker serviks