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All Journal e-CliniC Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Bismarck J. Laihad
Faculty of Medicine University of Sam Ratulangi/ Prof. Dr. R.D. Kandou General Hospital Manado
Health Professions Medicine & Pharmacology Public Health

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HE4 has a High Diagnostic Value to Detect Epithelial Ovarian Cancer Laihad, Bismarck J.
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.209 KB)

Abstract

Objective: To find out the diagnostic value of CA125 and HE4 as a tumor marker, and also RMI and ROMA as a malignancy predictor in patients with ovarian tumors. Methods: This study was a diagnostic study using cross-sectional design.This study was performed in Jakarta from November 2010 to May 2011. One hundred and twenty eight serum samples of patients diagnosed with ovarian tumors were collected before undergoing surgery in Dr. Cipto Mangunkusumo General Hospital. The CA125 and HE4 levels were then examined. The histopathological examination of tissue specimens were performed in Department of Pathology Anatomy in RSCM. For statistical analysis, we used a 2x2 table to produce ROC-AUC curve. Results: The median value of HE4 and CA125 serum concentrations was higher and more significant on patients with ovarian malignancy than patients with benign ovarian tumor (p
HE4 has a High Diagnostic Value to Detect Epithelial Ovarian Cancer Laihad, Bismarck J.
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.209 KB) | DOI: 10.32771/inajog.v1i4.368

Abstract

Objective: To find out the diagnostic value of CA125 and HE4 as a tumor marker, and also RMI and ROMA as a malignancy predictor in patients with ovarian tumors. Methods: This study was a diagnostic study using cross-sectional design.This study was performed in Jakarta from November 2010 to May 2011. One hundred and twenty eight serum samples of patients diagnosed with ovarian tumors were collected before undergoing surgery in Dr. Cipto Mangunkusumo General Hospital. The CA125 and HE4 levels were then examined. The histopathological examination of tissue specimens were performed in Department of Pathology Anatomy in RSCM. For statistical analysis, we used a 2x2 table to produce ROC-AUC curve. Results: The median value of HE4 and CA125 serum concentrations was higher and more significant on patients with ovarian malignancy than patients with benign ovarian tumor (p
Insiden dan Mortalitas Penderita Kanker Serviks di RSUP Prof. Dr. R. D. Kandou Periode Januari 2014 - September 2015 Mamesah, Frits; Laihad, Bismarck J.; Kaeng, Juneke J.
e-CliniC Vol 6, No 1 (2018): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v6i1.19501

Abstract

Abstract: Cervical cancer is caused by human papiloma virus (HPV). It is a malignant disease in obstetrics and gynecology field which still occupies the highest position cancer among females woman. This study was aimed to obtain the incidence and mortality of cervical cancer patients at Prof. Dr. R. D. Kandou Hospital Manado from january 2014- september 2015. This was a descriptivease retrospective study using patients’ medical record data of cervical cancer. The results showed that there were 121 patients of cervical cancer, most were in the age group of 41-50 years (39.67%) and stage III B (41 people; 33.89%); 23 patients (19.00%) died. Conclusion: The incidence of cervical cancer at Prof. Dr. R. D. Kandou Hospital Manado was high enough with a mortality rate of 19.00%.Keywords: cervical cancer Abstrak: Kanker serviks disebabkan oleh Human Papiloma Virus (HPV) dan merupakan salah satu penyakit keganasan di bidang obstetrik dan ginekologi yang masih menempati posisi tertinggi sebagai penyakit kanker yang menyerang kaum perempuan. Penelitian ini bertujuan untuk mengetahui insiden dan mortalitas pasien kanker serviks di RSUP Prof. Dr. R. D. Kandou Manado sejak Januari 2014-Septemper 2015. Jenis penelitian ialah deskriptif retrospektif dengan menggunakan data rekam medik pasien kanker serviks. Hasil penelitian mendapatkan 121 kasus kanker serviks, terbanyak pada kelompok usia 41-50 tahun (39,67%). Kebanyakan pasien berada pada stadium IIIB sebanyak 41 orang (33,89%) dan 23 penderita (19,00%) dinyatakan meninggal dunia. Simpulan: Insiden penderita kanker serviks di RSUP Prof. Dr. R. D. Kandou Manado cukup tinggi dengan angka mortalitas sebesar 19,00%.Kata kunci: kanker serviks
Effect Knowledge and Attitude with Behaviour of HPV Vaccination in Women of Reproductive Age: Pengaruh Pengetahuan dan Sikap dengan Perilaku Vaksinasi HPV pada Wanita Usia Reproduksi Darmawan, Budi; Laihad, Bismarck J.; Wagey, Frank M. M.
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 1 January 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i1.1736

Abstract

To observe the association between knowledgeand attitude towards HPV vaccination with the behaviortowards HPV vaccination on reproductive woman inIndonesia.Methods: We conducted observational analytic studywith cross-sectional design. The study was conducted inobstetric and gynecologic outpatient clinic in Prof. Dr. R.D. Kandou General Hospital, Manado Indonesia throughJuly and August 2021. Reproductively active woman wereincluded as the subject. Univariate and bivariate analysiswere conducted in this study.Results: We included 364 reproductive woman. The majorityof the subject were 20-35 year-old woman (50.8%) and weremarried (61.3%). The majority of the subject (72.8%) havereceived information about HPV vaccination. We foundsignificant association between knowledge and attitudewith the OR of 5.57 (p=0.00). Knowledge and attitudeshowed significant association with eagerness towards HPVvaccination. However, knowledge and behavior did notshow any significant association towards HPV vaccinationbehavior.Conclusion: There is a significant association betweenknowledge and attitude of HPV vaccination with eagernesstoward HPV vaccination in reproductive women in Indonesia.Keywords: behavior, HPV vaccination, knowledge,reproductive women. Keywords: behavior, HPV vaccination, knowledge,reproductive women. AbstrakTujuan: Untuk mengetahui hubungan pengetahuan dansikap terhadap perilaku vaksinasi HPV pada perempuan usiareproduktif di RSUP Prof. DR. R. D. Kandou, Manado.Metode: Penelitian ini merupakan penelitian analitikobservasional dengan pengambilan subjek potong lintang.Penelitian dilakukan di unit pelayanan bagian Obstetri danGinekologi RSUP Prof. Dr. R. D. Kandou Manado pada Juli-Agustus 2021. Subjek penelitian merupakan perempuanusia reproduktif yang bersedia untuk mengikuti penelitianini. Analisis data akan dilakukan secara univariat dan bivariatserta dilaporkan pada penelitian ini.Hasil: Penelitian ini mencakup 364 perempuan dengan usiaproduktif. Mayoritas subjek merupakan perempuan denganusia 20-35 tahun (50,8%) dan sudah menikah (61,3%).Mayoritas subjek (72,8%) pernah mendapatkan informasivaksinasi HPV sebelumnya. Hubungan antara pengetahuandan sikap terhadap vaksinasi menunjukkan hasil yangsignifikan (p=0,00) dengan OR 5,57. Pengetahuan dansikap juga menunjukkan hubungan yang signifikan dengankesediaan vaksin (p<0,05). Pengetahuan dan sikap tidakmenunjukkan hubungan yang bermakna terhadap perilakuvaksin (p>0,05).Kesimpulan: Terdapat hubungan yang bermakna antarapengetahuan dan sikap dengan perilaku keinginan vaksinasiHPV pada perempuan usia reproduktif.Kata kunci: pengetahuan, perempuan usia reproduktif,sikap, Vaksinasi HPV.
Co-Authors Budi Darmawan Frank M. M. Wagey, Frank M. M. Juneke J. Kaeng Mamesah, Frits