Juneke J. Kaeng
Department of Obstetric and Gynecology, Faculty of Medicine, Sam Ratulangi University, Medan

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The status of probiotics supplementation during pregnancy Wibowo, Noroyono; Mose, Johanes C.; Karkata, Made K.; Purwaka, Bangun T.; Kristanto, Herman; Chalid, Maisuri T.; Yusrawati, Yusrawati; Sitepu, Makmur; Kaeng, Juneke J.; Bernolian, Nuswil; Prasmusinto, Damar; Irwinda, Rima
Medical Journal of Indonesia Vol 24, No 2 (2015): June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (514.372 KB) | DOI: 10.13181/mji.v24i2.1223

Abstract

Probiotics have been known for their use in medical field for quite a long time. Strong evidences are now available for the use of probiotics in clinical setting. One of the current issues on this topic is the use of probiotics in pregnancy. Recent studies showed that probiotics may be safe and beneficial for prenatal supplementation. In this review, we highlighted several proven use of probiotics supplementation in pregnant women. A few selected strains of probiotics showed promising outcome to prevent preterm labor and preeclampsia, and to reduce atopic eczema but not asthma and wheezing, in offspring of women who had prenatal probiotics supplementation. The mechanism of action responsible for this effect is closely related to the regulation of T cells, although the exact pathways are not defined yet.
Creatinine clearance levels are associated with the incidence of preeclampsia Sanusi, Jesslyn M; Tendean, Hermie M. M.; Kaeng, Juneke J.
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.899 KB) | DOI: 10.32771/inajog.v6i4.843

Abstract

Abstract Objective: Determine thecorrelation between creatinine clearance relationship with preeclampsia incidence. Method: Cross sectional research. Result: Creatinine clearance examination conducted on 60 sample of pregnant women > 20 weeks,30 normotensive samples and 30 preeclampsia samples. The obtained data analyzed using SPSS software version 22.0 and discussed using the existing literature theory. Creatinine clearance average level in normotensive pregnancy 124.650 ± 14.3699ml/minutes/1,73m2and preeclampsia 74.003 ± 23.169ml/minutes/1,73m2. After Mann-Whitney statistical test obtained p value = 0,000. From ROC curve analysis for creatinine clearance obtained sensitivityvalue 100% and specificity 99,53%. Conclusion:There is a significant correlation between the creatinine clearance levels with preeclampsia. Keywords: creatinine clearance, normotensive, preeclampsia.   Abstrak Tujuan: Menentukan hubungan antara creatinine clearance dengan kejadian preeklamsia. Metode: Penelitian potong lintang. Hasil:Dilakukan pemeriksaan creatinine clearance pada 60 sampel ibuhamil > 20 minggu, 30 sampel darah normal dan 30 sampel preeklamsia. Data yang diperoleh dianalisa dengan menggunakan software SPSS versi 22.0 dan dibahas dengan menggunakan  teori literatur yang ada. Kadar rerata creatinine clearance pada kehamilan normotensi 124,650 ± 14,3699 ml / menit / 1,73m2 dan preeklampsia 74,003 ± 23,169 ml / menit / 1,73m2. Setelah uji statistik Mann-Whitney diperoleh nilai p = 0,000. Dari analisis kurva ROC untuk creatinine clearance diperoleh nilai sensitivitas 100% dan spesifisitas 99,53%. Kesimpulan: Ada hubungan yang signifikan  antara creatinine clearance dengan kejadian preeklamsia. Kata kunci: creatinine clearance, normotensi, preeklampsia.
Creatinine clearance levels are associated with the incidence of preeclampsia Sanusi, Jesslyn M; Tendean, Hermie M. M.; Kaeng, Juneke J.
Indonesian Journal of Obstetrics and Gynecology Volume 6 No. 4 October 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.899 KB) | DOI: 10.32771/inajog.v6i4.843

Abstract

Abstract Objective: Determine thecorrelation between creatinine clearance relationship with preeclampsia incidence. Method: Cross sectional research. Result: Creatinine clearance examination conducted on 60 sample of pregnant women > 20 weeks,30 normotensive samples and 30 preeclampsia samples. The obtained data analyzed using SPSS software version 22.0 and discussed using the existing literature theory. Creatinine clearance average level in normotensive pregnancy 124.650 ± 14.3699ml/minutes/1,73m2and preeclampsia 74.003 ± 23.169ml/minutes/1,73m2. After Mann-Whitney statistical test obtained p value = 0,000. From ROC curve analysis for creatinine clearance obtained sensitivityvalue 100% and specificity 99,53%. Conclusion:There is a significant correlation between the creatinine clearance levels with preeclampsia. Keywords: creatinine clearance, normotensive, preeclampsia.   Abstrak Tujuan: Menentukan hubungan antara creatinine clearance dengan kejadian preeklamsia. Metode: Penelitian potong lintang. Hasil:Dilakukan pemeriksaan creatinine clearance pada 60 sampel ibuhamil > 20 minggu, 30 sampel darah normal dan 30 sampel preeklamsia. Data yang diperoleh dianalisa dengan menggunakan software SPSS versi 22.0 dan dibahas dengan menggunakan  teori literatur yang ada. Kadar rerata creatinine clearance pada kehamilan normotensi 124,650 ± 14,3699 ml / menit / 1,73m2 dan preeklampsia 74,003 ± 23,169 ml / menit / 1,73m2. Setelah uji statistik Mann-Whitney diperoleh nilai p = 0,000. Dari analisis kurva ROC untuk creatinine clearance diperoleh nilai sensitivitas 100% dan spesifisitas 99,53%. Kesimpulan: Ada hubungan yang signifikan  antara creatinine clearance dengan kejadian preeklamsia. Kata kunci: creatinine clearance, normotensi, preeklampsia.
Insiden dan Mortalitas Penderita Kanker Serviks di RSUP Prof. Dr. R. D. Kandou Periode Januari 2014 - September 2015 Mamesah, Frits; Laihad, Bismarck J.; Kaeng, Juneke J.
e-CliniC Vol 6, No 1 (2018): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v6i1.19501

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Abstract: Cervical cancer is caused by human papiloma virus (HPV). It is a malignant disease in obstetrics and gynecology field which still occupies the highest position cancer among females woman. This study was aimed to obtain the incidence and mortality of cervical cancer patients at Prof. Dr. R. D. Kandou Hospital Manado from january 2014- september 2015. This was a descriptivease retrospective study using patients’ medical record data of cervical cancer. The results showed that there were 121 patients of cervical cancer, most were in the age group of 41-50 years (39.67%) and stage III B (41 people; 33.89%); 23 patients (19.00%) died. Conclusion: The incidence of cervical cancer at Prof. Dr. R. D. Kandou Hospital Manado was high enough with a mortality rate of 19.00%.Keywords: cervical cancer Abstrak: Kanker serviks disebabkan oleh Human Papiloma Virus (HPV) dan merupakan salah satu penyakit keganasan di bidang obstetrik dan ginekologi yang masih menempati posisi tertinggi sebagai penyakit kanker yang menyerang kaum perempuan. Penelitian ini bertujuan untuk mengetahui insiden dan mortalitas pasien kanker serviks di RSUP Prof. Dr. R. D. Kandou Manado sejak Januari 2014-Septemper 2015. Jenis penelitian ialah deskriptif retrospektif dengan menggunakan data rekam medik pasien kanker serviks. Hasil penelitian mendapatkan 121 kasus kanker serviks, terbanyak pada kelompok usia 41-50 tahun (39,67%). Kebanyakan pasien berada pada stadium IIIB sebanyak 41 orang (33,89%) dan 23 penderita (19,00%) dinyatakan meninggal dunia. Simpulan: Insiden penderita kanker serviks di RSUP Prof. Dr. R. D. Kandou Manado cukup tinggi dengan angka mortalitas sebesar 19,00%.Kata kunci: kanker serviks
GAMBARAN PERSALINAN PADA PROGRAM JAMPERSAL DI RSU PROF. DR. R. D KANDOU MANADO Tondolambung, Priscillia; Tendean, Hermie; Kaeng, Juneke J.
e-Biomedik Vol 1, No 1 (2013): eBiomedik
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ebm.v1i1.4598

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Abstract: Jampersal stand for financing service childbirth is covering to examine the pregnancy, birth aid, the parturition, including family planning service post delivery and newborn service performed by health professionals in health facilities. The purpose of this study was to know description of childbirth on Jampersal program at Prof. Dr. R. D Kandou. This research used retrospective descriptive methods. The sample in this study were all of the birthing mother who used Jampersal at Prof. Dr. R. D Kandou general hospital Manado from April to December 2011. This study has shown indicate that there are 2800 delivery cases was found using the Jampersal program from 3561 total of childbirth. Most childbirth which used Jampersal program is followed by multigravida (55,18%) at the age of 20 to 25 years (29,00%). Most woman came directly to the hospital (71,82%) and treated in hospital for more than 3 days (39,11%). Most labors using the Jampersal program were commonly aided spontaneously (66,93%). Conclusion: Description of childbirth on Jampersal program at Prof. Dr. R. D Kandou General Hospital most was followed by multigravida, at the age of 20-25 years, came directly to the hospital, treated for more than 3 days, and aided spontaneously. Keywords: Jampersal, Childbirth.     Abstrak: Jampersal adalah jaminan pembiayaan pelayanan persalinan yang meliputi pemeriksaan kehamilan, pertolongan persalinan, pelayanan nifas termasuk pelayanan Keluarga Berencana (KB) paska persalinan dan pelayanan bayi baru lahir yang dilakukan oleh tenaga kesehatan di fasilitas kesehatan.Tujuan penelitian ini untuk mengetahui gambaran persalinan pada program Jampersal di RSU Prof. Dr. R. D Kandou. Penelitian ini menggunakan metode retrospektif deskriptif. Sampel penelitian yaitu semua ibu bersalin dengan program Jampersal di RSU Prof. Dr. R. D Kandou periode April - Desember 2011. Hasil penelitian menunjukkan bahwa terdapat 2800 kasus persalinan menggunakan program Jampersal dari 3561 total persalinan. Kebanyakan persalinan dengan menggunakan program Jampersal diikuti oleh ibu yang multigravida (55,18%) dengan usia 20-25 tahun (29,00%). Ibu yang bersalin paling banyak langsung datang sendiri ke rumah sakit (71,82%) dan kebanyakan dirawat di rumah sakit selama lebih dari 3 hari (39,11%). Persalinan menggunakan program Jampersal paling sering ditolong secara spontan (66,93%). Simpulan: Gambaran persalinan pada program Jampersal di RSU Prof. Dr. R. D Kandou kebanyakan diikuti oleh ibu yang multigravida, usia 20-25 tahun, langsung datang sendiri ke rumah sakit, dirawat selama lebih dari 3 hari dan ditolong secara spontan. Kata kunci: Jampersal, Persalinan.
HUBUNGAN INDEKS MASSA TUBUH IBU DAN PENINGKATAN BERAT BADAN SAAT KEHAMILAN DENGAN PREEKLAMPSIA Quedarusman, Hermanto; Wantania, John; Kaeng, Juneke J.
e-Biomedik Vol 1, No 1 (2013): eBiomedik
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ebm.v1i1.4363

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Abstract: Preeclampsia is a health problem that occurs when a pregnancy reaches 20 weeks or more, preeclampsia is accompanied by hypertension and protenuria as main signs. Women with obesity before pregnancy are known to have higher risk to get preeclampsia during pregnancy than those with normal IMT. Excessive weight gain during pregnancy can also increase the risk of preeclampsia in pregnant woman. The purpose of this research is to examine the relationship between maternal body mass index and weight gain during pregnancy with preeclampsia.This research used observasional-analytic method through case-control approach. The number of case group is 38 people and the number of control group is 38 people. The result shows that at risk women were four times more likely to develop preeclampsia during pregnancy than those with normal IMT (OR= 4,32 95% CI= 1,15-16,12), and obese women were five times more likely to develop preeclampsia during pregnancy than those with normal IMT (OR= 5,06 95% CI= 1,46-12,67). The result also shows that women with excessive weight gain during pregnancy were almost three times more likely to develop preeclampsia during preeclampsia than women with normal weight gain during pregnancy (OR=2,53 95% IK= 0,99-31,81). The results show that there is a significant association between maternal IMT and weight gain during pregnancy with preeclampsia. Key Word: BMI, obesity, pregnancy and preeclampsia     Abstrak: Preeklampsia adalah masalah kesehatan yang terjadi pada usia kehamilan 20 minggu ke atas dengan tanda utama hipertensi dan protenuria. Wanita dengan obesitas sebelum kehamilan memiliki risiko lebih besar untuk menderita preeklampsia dibandingkan wanita normal. Peningkatan berat badan berlebihan saat kehamilan juga dapat meningkatkan risiko terjadinya preeklampsia pada wanita hamil. Tujuan dari penelitian ini yaitu untuk mengetahui hubungan antara indeks massa tubuh (IMT) ibu dan peningkatan berat badan saat kehamilan dengan preeklampsia. Penelitian ini menggunakan metode observasional-analitik dengan desain case-control. Jumlah sampel untuk kelompok kasus 38 orang dan untuk kelompok kontrol 38 orang. Hasil dalam penelitian ini menunjukkan bahwa kelompok IMT at risk berisiko empat kali lebih besar untuk menderita preeklampsia dibandingkan kelompok IMT normal (OR= 4,32 95% IK= 1,15-16,12), sedangkan kelompok IMT obesitas berisiko lima kali lebih besar untuk menderita preeklampsia dibandingkan kelompok IMT normal (OR= 5,06 95% IK= 1,46-12,67). Kelompok dengan peningkatan berat badan tinggi berisiko hampir tiga kali lebih besar untuk menderita preeklampsia dibandingkan wanita dengan peningkatan berat badan saat hamil normal (OR=2,53 95% IK= 0,99-31,81). Hasil penelitian ini menunjukkan bahwa terdapat hubungan bermakna antara indeks massa tubuh ibu dan peningkatan berat badan saat kehamilan dengan preeklampsia. Kata Kunci: IMT, obesitas, kehamilan, dan preeklampsia.
KARAKTERISTIK PERSALINAN KEMBAR DI RSUP PROF DR. R. D. KANDOU MANADO TAHUN 2012 – 2013 Lumempow, Irmi; Kaeng, Juneke J.; Rarung, Max R.
e-CliniC Vol 3, No 1 (2015): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v3i1.6762

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Abstract: Some factors (as maternal characteristics), which play a role in multiple pregnancies, such as maternal age, parity, and heredity. As for the infant risk factors in multiple deliveries, such as gestational age, birth weight, and APGAR Score. This study provides a description of maternal characteristics and infant risk factors in multiple deliveries in the Prof. Dr. R. D. Kandou Manado Hospital during 2012 to 2013. The results are most of maternal characteristics who performed multiple deliveries in the Prof. Dr. R. D. Kandou Manado Hospital were between 30-34 years of age, second parity, 64% positive in heredity factor, and 73% performed vaginal delivery. The majority of infant risk factors were gestational age in deliveries averaged over 37-40 weeks, with birth weight under 2500 grams and APGAR Score 7-9.Keywords: multiple deliveries, maternal characteristics, infant risk factorAbstrak: Faktor-faktor sebagai karakteristik ibu, yang dapat memicu kehamilan kembar, antara lain faktor usia, jumlah paritas, dan faktor hereditas. Adapun faktor-faktor risiko bayi dalam persalinan kembar, antara lain usia kehamilan sang ibu, berat badan lahir bayi, serta APGAR Score bayi. Penelitian ini memberikan gambaran mengenai karakteristik ibu dan faktor risiko bayi, khususnya dalam persalinan kembar di RSUP Prof Dr. R. D. Kandou Manado periode 1 Januari 2012 sampai dengan 31 Desember 2013. Hasil yang didapatkan adalah kelompok usia ibu terbanyak adalah 30 tahun – 34 tahun, jumlah paritas terbanyak adalah paritas 2, 64% faktor hereditas positif, serta 73% dilakukan persalinan pervaginam. Pada faktor risiko bayi, didapatkan yang terbanyak bayi kembar lahir pada usia kehamilan 37 minggu – 40 minggu, banyak bayi memiliki berat badan lahir di bawah 2500 gram, dan APGAR Score 7 – 9.Kata kunci: persalinan kembar, karakteristik ibu, faktor risiko bayi
HUBUNGAN PENGGUNAAN KONTRASEPSI DENGAN KEJADIAN KEHAMILAN EKTOPIK TERGANGGU DI BLU RSUP PROF. DR. R. D. KANDOU MANADO PERIODE 2009 – 2013 Aling, Deanette M. R.; Kaeng, Juneke J.; Wantania, John
e-CliniC Vol 2, No 3 (2014): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v2i3.5758

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Abstract: Ectopic pregnancy accounts for 1 in 200 (5-6%) maternal mortality in developed countries.2 According to the WHO, with over 60 000 annual cases in Indonesia– that is 3% of its population, the number of ectopic pregnancies in Indonesia is estimated to be on the brink to cases in developed countries.6 A risk factor for ectopic pregnancy that has surged over the years is the use of contraceptive methods. According to the research at the Department of Epidemiology and Social Medicine University of Brussels in the 90s and two consecutive research the at the Department of Obstetrics and Gynecology BLU RSUP Prof. dr. R. D. Kandou Manado in 2001 and 2011, the use of contraceptive methods have proven to have significant correlation with the incidence of ectopic pregnancy (p>0.05).5,10The issues above are what underlie the aim of this research – that is to investigate the possibility for ectopic pregnancies to occur in patients diagnosed with ectopic pregnancy with prior use of contraceptive methods at the Department of Obstetrics and Gynecology BLU RSUP Prof. dr. R. D. Kandou Manado from October 2009 – October 2013. The method applied for this research is by performing a 5 year retrospective study - analyzing the number of patients with ectopic pregnancy as well as those with prior use of contraceptive methods. The result from a Chi-Square analysis is p = 0.457, where if p < 0.05, means there is a significant correlation. Thus with such result, it is proven that there is no significant correlation between the use of contraceptive methods with the incidence of ectopic pregnancy. Keywords: ectopic pregnancy, contraceptive methods.   Abstrak: Kehamilan Ektopik Terganggu (KET) merupakan penyebab 1 dari 200 (5-6%) mortalitas maternal di negara maju.2 Dengan 60.000 kasus setiap tahun atau 3% dari populasi masyarakat, angka kejadian KET di Indonesia diperkirakan tidak jauh berbeda dengan negara maju, menurut WHO.6 Adapun salah satu faktor risiko KET yang dinilai semakin meningkat dewasa ini adalah pemakaian alat-alat/ metode kontrasepsi. Ditinjau dari penelitian di Department of Epidemiology and Social Medicine University of Brussels pada tahun 90an dan penelitian di BLU RSUP Prof. dr. R. D. Kandou Manado pada tahun 2001 dan 2011, pemakaian alat kontrasepsi dengan kejadian KET memiliki hubungan yang signifikan, dengan p > 0.05. Masalah tersebut yang menjadi dasar tujuan penelitian ini, yaitu untuk menindaklanjuti kemungkinan terjadinya KET pada pasien-pasien KET dengan riwayat pemakaian kontrasepsi, dengan memberikan gambaran mengenai data-data kasus KET dengan riwayat  penggunaan kontrasepsi yang diperiksa di bagian Obstetri dan Ginekologi BLU RSUP Prof. dr. R. D. Kandou Manado periode Oktober 2009 – Oktober 2013.Metode yang digunakan pada penelitian ini adalah dengan melakukan studi retrospektif, yaitu dengan melakukan pendataan jumlah pasien KET, serta riwayat penggunaan kontrasepsi oleh pasien-pasien KET tersebut dalam kurun waktu 5 tahun. Hasil yang ditemukan memperlihatkan hasil uji Chi-Square adalah p = 0.457, dimana jika nilai p < 0.05, maka dikatakan terdapat hubungan yang signifikan. Oleh karena nilai p pada uji Chi-Square di tabel 4.4.A >0.05, maka dapat dikatakan bahwa tidak terdapat hubungan yang signifikan antara riwayat penggunaan kontrasepsi dengan kejadian KET. Kata kunci: KET (Kehamilan Ektopik Terganggu), kontrasepsi.
KARAKTERISTIK PERSALINAN LETAK SUNGSANG DI RSUP PROF. DR. R. D. KANDOU MANADO PERIODE 1 JANUARI 2014 – 31 DESEMBER 2014 Silinaung, Matricia Delaros G.; Kaeng, Juneke J.; Suparman, Erna
e-CliniC Vol 4, No 1 (2016): Jurnal e-CliniC (eCl)
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v4i1.10984

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Abstract: The cause of breech presentation is unknown, but there are some risk factors besides prematurity such as structural abnormality of the uterus, polyhydramnion, placenta previa, multiparity, uterine myoma, multiple pregnancy, fetal anomalies (anencephaly, hydrocephalus), and previous history of breech presentation. Before the age of 28 weeks, the incidence of breech presentation ranges from 25-30%, and most fetus will turn into a cephalic presentation after 34 weeks of gestation. This study aimed to determine the characteristics of breech delivery.This was a descriptive retrospective study using medical records of Prof. Dr. R. D. Kandou Hospital Manado period 1 January 2014 – 31 December 2014. This study obtained 214 cases of breech delivery out of the total of 3,347 deliveries. Breech delivery was most common in multigravida, at the age of 37-41 weeks The most common type of presentation was incomplete breech presentation and the management of labour was mostly per vaginam (spontaneous Bracht). Birthweights were more common in the range of 2500 - 3999 grams and the newborn babies were not asphyxiated. Complications were rarely found, however, there were 15 cases of infant death. Keywords: breech delivery, breech presentation Abstrak: Penyebab terjadinya presentasi bokong tidak diketahui, tetapi terdapat beberapa faktor risiko selain prematuritas, yaitu abnormalitas struktural uterus, polihidramnion, plasenta previa, multiparitas, mioma uteri, kehamilan multiple, anomali janin (anensefali, hidrosefalus), dan riwayat presentasi bokong sebelumnya.Sebelum umur kehamilan 28 minggu, kejadian presentasi bokong berkisar antara 25-30%, dan sebagian besar akan berubah menjadi presentasi kepala setelah umur kehamilan 34 minggu.Tujuan penelitian ini untuk mengetahui karakteristik dari persalinan letak sungsang. Penelitian ini menggunakan metode deskriptif retrospektif melalui rekam medik di RSUP Prof. dr. R. D. Kandou Manado periode 1 Januari 2014 – 31 Desember 2014. Dari penelitian ini diperoleh 214 kasus persalinan letak sungsang dari total persalinan 3.347 persalinan. Persalinan letak sungsang paling banyak ditemukan pada multigravida, kelompok usia kehamilan 37 – 41 minggu, jenis presentasi bokong kaki (incomplete breech) dengan penanganan paling banyak ialah persalinan pervaginam (spontaneus Bracht). Berat badan lahir bayi letak sungsang paling sering berkisar 2500 – 3999 gram, umumnya bayi tidak mengalami asfiksia. Walaupun jarang ditemukan komplikasi, mortalitas bayi letak sungsang terdapat sebanyak 15 kasus.Kata kunci: persalinan letak sungsang, presentasi letak sungsang