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All Journal PROSIDING SEMINAR KIMIA Fullerene Journal of Chemistry Journal of Patchouli and Essential Oil Products
Binawati Ginting
Universitas Syiah Kuala
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Medicine & Pharmacology

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UJI TOKSISITAS EKSTRAK DAUN (Myristica fragrans Houtt) DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) Binawati Ginting; Tonel Barus; Lamek Marpaung; Partomuan Simanjuntak
PROSIDING SEMINAR KIMIA SEMINAR NASIONAL KIMIA 2014
Publisher : PROSIDING SEMINAR KIMIA

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Abstract

Tumbuhan Pala (Myristica fragrans Houtt) termasuk dalam famili Myristicaceae. Penelitian tentang ekstraksi daun Pala dan uji toksisitasnya dengan metode Brine Shrimp Lethality Test (BSLT) telah dilakukan. Ekstraksi 3 Kg (3000 g) daun Pala dengan metanol diperoleh ekstrak metanol 417,60 g (13,92%). Ekstrak metanol d i larutkan ke dalam et il asetat diperoleh ekstrak et il asetat 104,1 g (5,96%). Hasil part isi ekstrak etil asetat dengan n-heksana diperoleh esktrak n-heksana 67,24 (68,53%) dan totalflavonoid 32,76 g (31,47%). Hasil uji akt ivitas sitotoksik ekstrak etil asetat, total flavonid metanol, dan n-heksana dengan metode Brine Shrimp Lethality Test (BSLT) berturut-turut LC 50 15,34 pp m; 30,92 pp m; 89,72 pp m dan 118,00 pp m.
Evaluation of Physical Quality of Patchouli Oil (Pogostemon cablin Benth.) Body Butter Formulation Nadia Isnaini; Khairan Khairan; Meutia Faradhilla; Elly Sufriadi; Binawati Ginting; Vicky Prajaputra; Friesca Erwan; Raihan Dara Lufika; Syaifullah Muhammad
Journal of Patchouli and Essential Oil Products JOURNAL OF PACTHOULI AND ESSENTIAL OIL PRODUCT : VOLUME 1, ISSUE 1 (JUNE 2022)
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.546 KB) | DOI: 10.24815/jpeop.v1i1.23762

Abstract

Patchouli oil (Pogostemon cablin Benth.) has antioxidant and antibacterial activities that can be used as an active ingredient in cosmetic products, such as body butter. Body butter preparations have the highest oil content. Therefore, they usually have the shortest storage period because they can easily damage during the storage period. The study aimed to evaluate the physical quality of patchouli oil body butter formulation in an accelerated stability test process for seven cycles. The formula was tested for its physical stability by organoleptic test, homogeneity, pH, absorption, adhesion, and dispersibility. Preparation evaluation was carried out in each cycle and analyzed using Student's t-test. The evaluation result of body butter preparation showed no significant difference (p 0.05) in the preparation in each cycle. Therefore, it can be concluded that the body butter formulation of patchouli oil was stable during the storage period for ± six months.
Fractionation, Purification, and Toxicity of Methanolic Cacao Pod Husk Extract (Theobroma cacao L.) Agnia Purnama; Mustanir Yahya; Binawati Ginting; Nurdin Saidi; Muhammad Ridha Afifi; Ruhul Maghfirah; Mutia Farida; Ikhsan Ikhsan
Jurnal Kimia Fullerene Vol 11 No 2: Fullerene Journal Of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37033/fjc.v11i2.772

Abstract

Cacao (Theobroma cacao, L.) is a plantation product that has good prospects, but its processing produces a by-product in the form of cacao pod husks that have not been optimally utilized. This study aims to analyze the toxicity of methanol extracts, fractions, and subfractions of cacao pod husks using the Brine shrimp lethality test (BSLT) assay, and to purify active compounds using gravity column chromatography and thin-layer chromatography (TLC). The fractionation process of the methanol extract produced 5 fractions and 4 subfractions. The results of the toxicity analysis showed that the TCM 2 fraction and the TCM 2.1 subfraction had the highest toxicity, with IC₅₀ values of 38.68 ppm and 28.85 ppm, respectively. Further purification process produced a single isolate identified as a terpenoid compound. The results of this study indicate that cacao pod husks have the potential to serve as a natural source of toxicity and can be developed for use in the pharmaceutical field.
Co-Authors Agnia Purnama Elly Sufriadi Friesca Erwan Ikhsan Ikhsan Khairan Khairan Lamek Marpaung Meutia Faradhilla Muhammad Ridha Afifi Mustanir Yahya Mutia Farida Nadia Isnaini Nurdin Saidi Partomuan Simanjuntak Raihan Dara Lufika Ruhul Maghfirah Syaifullah Muhammad Tonel Barus Vicky Prajaputra