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All Journal Saintifika Majalah Kedokteran Sriwijaya ACCRUALS (Accounting Research Journal of Sutaatmadja) International Journal of Marine Engineering Innovation and Research JURNAL PENDIDIKAN, SAINS DAN TEKNOLOGI Jurnal Riset Fisika Indonesia JIPOR: Jurnal Iptek Olahraga dan Rekreasi SAINTIFIKA Journal of Global Pharma Technology Jurnal Pengabdian Fakultas Pertanian Universitas Lampung Jurnal Iptek Olahraga dan Rekreasi
Rusdianto Rusdianto
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Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Other

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Journal : Majalah Kedokteran Sriwijaya

 1 
C-KIT EXPRESSION IN VARIOUS DEGREES OF HISTOPATHOLOGY DIFFERENTIATION OF RETINOBLASTOMA IN MOHAMMAD HOESIN HOSPITAL PALEMBANG Rusdianto Rusdianto; Keisha Devita Primananda
Majalah Kedokteran Sriwijaya Vol 52, No 2 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i2.11978

Abstract

Retinoblastoma is a malignant intraocular neoplasm in pediatric which composed of embyonic tumour cells from retinoblasts of neuroepithelial origin with a relative incidence of 3% of all pediatric tumours. Histopathology examination can confirmed the diagnosis of retinoblastoma. Immunohistochemical staining with C-kit antibody can be used to identify the expression of C-kit in paraffin block of retinoblastoma sample.This study was conducted to identify C-kit expresion in various degrees of histopathology differentiation’s retinoblastoma in Mohammad Hoesin Hospital Palembang.. A descriptive study used on the paraffin blocks of 19 cases retinoblastoma in RSUP dr. Mohammad Hoesin from January 2012- July 2017. The degree of histopathologic differentiation and invasion of retinoblastoma was investigated by Hematoksilin-Eosin stain, and the C-kit expression stained by immunohistochemistry using antibody C-kit ready to use. Data was being presented in tabular form to identify C-kit expression. Retinoblastoma which expressed C-kit in this study are 63,16% among all sample. C-kit expressions were detected in 25% well differentiated, 50 % moderately differentiated, and 25% poorly differentiated of histopathological differentiation degree, also in 50% sample with optic nerve invasion and 58,33% in scleral invasion. C-kit expression was negative in 36,84% sample. In this study, C-kit expression was found more than half in retinoblastoma sample.
SEROLOGY AND MOLECULAR IDENTIFICATION OF RUBELLA VIRUS IN PEDIATRIC CATARACT AT MOEHAMMAD HOESIN PALEMBANG Rusdianto Rusdianto; Reny Violeta; Irsan Saleh
Majalah Kedokteran Sriwijaya Vol 52, No 3 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i3.12502

Abstract

Congenital cataract can be found 0.6 - 6 in every 10.000 births. The most etiology is the genetic abnormality but infection is the etiology that can be controlled. Rubella infection is about 10-15 % from all etiology of congenital cataract. Rubella virus is linked with congenital rubella syndrome (CRS). Today there is no data in Indonesia about identification of rubella virus in cataract lens. The purposed of this study to identify rubella virus in children with cataract by blood serology examination and molecular (PCR from lens). The design of this study was descriptive study and this is a pilot study about rubella virus in cataract lens in Indonesia. We had 9 samples - 15 eyes with congenital cataract and juvenile cataract from July 2016 until September 2016. We did blood serological examination IgG rubella, and PCR examination from lens which was taken from aspiration intraoperative. Result: from 15 eyes; 6 eyes PCR (+) with IgG rubella (+) (40 %), 2 eyes (13.33 %) PCR (-) but IgG (+), 4 eyes (26.67 %) with PCR (+) with igG (-), and 3 eyes (20 %) d PCR (-) with IgG (-). Overall from 9 samples there are 7 samples with PCR (+) rubella and 2 samples with PCR (-). There were 7 cases with rubella positive from 9 samples in the lens from pediatric cataract patient during July 2016 until September 2016. PCR examination from cataract lens is much more sensitive than serological blood examination.
Co-Authors ADITYA KURNIAWAN Ana Wardatul Jannah Anastasya Eka Saputri Andi Wahjono Budi Barata Kusuma Utami Christine Wulandari Dadang Hendrawan Diah Wahyuni Djanggan Sargowo Eddy Setyo Koenhardono Eka Ria Novita Sari Sirait Ilhafurroihan Apriliazmi Imran Saidi Indra Gumay Febryano Irsan Saleh Jayarani Fatimah Putri Juniarko Prananda Keisha Devita Primananda Kuswandono Kuswandono Liyana Aryanto Luh Putu Ratna Sundari Mifetika Lukitasari Miryanti Cahyaningtias Moh. Nu'man Ash Shiddieqiey Mursid Mursid Reny Violeta Rina Yudha Saifur Rohman Samsul Bakri Sasmojo Widito Slamet Budi Yuwono Sri Wahyuni Supeno Supeno Susanti Susanti Syachrul Ivandi Talitha Talitha Tri Kusmita Ulin Nuha widodo Ph.D yanna indrayana Yoan Melly Nurrahma Yuli Agustin Zainur Rasyid Ridlo