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All Journal Jurnal Riset Industri Hasil Hutan Pharmascience Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Journal of Islamic Scriptures in Non-Arabic Societies Prosiding SeNTIK STI&K
Khoerul Anwar
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences

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SINTESIS FEROMON 3-METIL 4-OKTANOL SEBAGAI ZAT PEMBASMI HAMA KUMBANG KELAPA Rhynchoporus spp. Evy Setiawati; Khoerul Anwar
Jurnal Riset Industri Hasil Hutan Vol 3, No 2 (2011)
Publisher : Kementerian Perindustrian

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.096 KB) | DOI: 10.24111/jrihh.v3i2.1191

Abstract

The compound of 3-methyl-4-octanol had been synthesized by the formation of Grignard reagent sec-buthyl magnesium bromide. The choosing of reactant 2-bromo butane and n-pentanal were resulted from retrosynthesize analysize of 3-methyl-4octanol pheromone. The reaction of sec-buthyl magnesium bromide was done at temperature 400C for 30 minutes, while the reaction between this reagent with n-pentanal was done for two hours. The formed compound was hydrolized using saturated NH4Cl solution and then cooled. The compound was identified using Infra Red spectrophotometre (IR), Gas Chromatography (GC), and Gas Chromatography-Mass Spectroscopy (GC-MS). The yield persentage of the compound was 12,70%.Keywords: synthesis, hydrolisis, pheromone, Grignard reagent, Rhynchoporus spp
FTIR and Chemometrics Application on Determination of Total Flavonoid Content of Pasak Bumi Root Extract (Eurycoma longifolia Jack.) Liling Triyasmono; Ana Ulfah; Muhammad Ikhwan Rizki; Khoerul Anwar; Totok Wianto; Heri Budi Santoso
Jurnal Pharmascience Vol 7, No 2 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.7923

Abstract

The combination of FTIR and chemometrics is an alternative method on determination of total flavonoid content of pasak bumi (Eurycoma longifolia Jack.) root extract. This study aims to determine the method of FTIR and chemometrics can be used for determination of total flavonoid content and determine the total flavonoid content of E. longifolia root extract using FTIR and chemometrics. The samples from three growing area were determined their flavonoid content by colorimetric method and measured their absorbance by FTIR spectrophotometer. The analysis was done by PCA chemometrics to grouping IR spectra based on growing area and PLSR to determine prediction model of total flavonoid content of E. longifolia root extract. The best grouping and prediction model is shown by IR spectra in the range of wavenumbers 1800-1540 cm-1 with  total variation is 99%  and prediction model with equation y = 0.995x + 0.002 (R2 calibration = 0.995; R2 validation = 0.970; RMSEC = 0.008; RMSECV = 0.021). The total flavonoid content of E. longifolia root extract (% b/b ± SD) from Mandiangin, Condong, and Sabuai is 0.225 ± 0.009; 0.437 ± 0.007; and 0.466 ± 0.016 (R2 = 0.995 and RMSEP = 0.008). Based on this, the combination of FTIR and chemometrics can be used to predict the total flavonoid content of unknown E. longifolia root extract
Evaluasi Kejadian Efek Samping pada Pasien Rheumatoid Arthritis yang Menggunakan DMARDs di Rumah Sakit di Banjarmasin Valentina Meta Srikartika; Khoerul Anwar; Amalia Amalia
Jurnal Pharmascience Vol 8, No 2 (2021): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v8i2.11681

Abstract

Rheumatoid Arthritis merupakan penyakit inflamasi kronis dengan pembengkakan, nyeri, dan kerusakan sendi. Obat yang digunakan pasien rheumatoid arthritis (RA) termasuk dalam Disease Modifying Anti-Rheumatoid Drugs (DMARDs) yang dilaporkan menyebabkan berbagai efek samping. Penelitian ini bertujuan untuk mengevaluasi kejadian efek samping dalam penggunaan DMARDs serta hubungan karakteristik pasien dan pola penggunaan DMARDs terhadap kejadian efek samping. Desain penelitian ini adalah cross sectional dengan pengambilan data secara retrospektive. Populasi penelitian adalah seluruh pasien RA yang memenuhi kriteria yang berobat rawat jalan di poli sub spesialis Rheumatology pada salah satu Rumah Sakit di Banjarmasin. Pasien RA yang mengalami efek samping pada penggunaan DMARDs berjumlah 45 pasien (80,36%). Efek samping yang terbanyak pada pasien RA ialah alopesia yaitu sebesar 26 kejadian (23,21%) serta yang terkecil ialah diare 6 kejadian (5,36%) dan retinopati sebesar 6 kejadian (5,36%). Terdapat hubungan bermakna antara jenis kelamin dengan kejadian alopesia (p-value  = 0,004), jenis obat dengan kejadian diare (p-value  = 0,003), dan lama pengobatan dengan kejadian ruam (p-value = 0,038). Berdasarkan penelitian dapat disimpulkan bahwa mayoritas pasien rawat jalan RA yang menggunakan DMARDs mengalami berbagai efek samping dan terdapat hubungan antara karakteristik dengan kejadian efek samping tertentu. Kata Kunci: Rheumatoid Arthritis (RA), Disease Modifying Anti-Rheumatoid Drugs (DMARDs), Efek samping, Karakteristik pasien, Alopesia, Diare, Retinopati  Rheumatoid Arthritis (RA) is a chronic inflammatory-disease characterized by joint’s swelling, pain, and damage. The drug used to treat patients with RA is categorised as Disease Modifying Anti-Rheumatoid Drugs (DMARDs) that has been reported has various side-effects. This study aimed to evaluate the profile of side-effect DMARDs use and the relationship of patient characteristics and DMARDs use to the incidence of adverse events. This study used cross sectional study design with retrospective data collection. The population were all RA outpatients that met the criteria treated in the poly sub-specialist Rheumatology Hospital in Banjarmasin. RA patients experienced adverse events on the use of DMARDs were 45 patients (80,36%). Most adverse events in RA patients were alopecia 26 events (23,21%) and the smallest was diarrhea 6 events (5,36%) and retinopathy of 6 events (5,36%). There was significant relation between sex and alopecia occurrence (p-value = 0,004), drug type and diarrhea occurrence (p-value = 0,003), and duration of treatment and rash occurrence (p-value = 0,038). It can be concluded that the majority of RA outpatients who use DMARDs experienced various side-effects and there was significant relationship between patient characteristics and particular side-effects.
Uji Karakteristik Fisik Sediaan Gel Ekstrak Daun Kirinyuh (Chromolaena odorata L.) dengan Variasi Karbopol dan HPMC Nurlely Nurlely; Aulia Rahmah; Prima Happy Ratnapuri; Valentina Meta Srikartika; Khoerul Anwar
Jurnal Pharmascience Vol 8, No 2 (2021): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v8i2.9346

Abstract

Daun Kirinyuh (Chromolaena odorata L) mengandung alkaloid, flavonoid, tannin, saponin, antrakuinon, glikosida dan terpenoid yang secara empiris digunakan sebagai obat luka. Gel merupakan sediaan farmasi yang lebih mudah diaplikasikan secara topical, tidak berminyak dan mudah untuk dibersihkan untuk menyembuhkan luka yang menggunakan gelling agent HPMC dan Karbopol. Penelitian ini bertujuan untuk menentukan pengaruh variasi konsentrasi HPMC dan karbopol terhadap karakteristik fisik sediaan gel ekstrak etanol daun kirinyuh (C. odorata). Sediaan gel dibuat dengan menggunakan ekstrak etanol daun kirinyuh 0,5% dan gelling agent HPMC dan karbopol dengan variasi konsentrasi dalam 3 formula serta bahan tambahan gel lainnya. Perbandingan HPMC dan karbopol untuk formula 1,2 dan 3 berturut-turut adalah : 70%:30% ; 50%:50% dan 30%:70%. Setelah itu dilakukan uji karakteristik fisik yaitu organoleptis, homegenitas, daya sebar, daya lengket, viskositas dan pH untuk ketiga formula. Hasil penelitian menunjukkan bahwa sediaan gel pada ketiga formula adalah berwarna hijau olive, berbau khas, konsistensi kental hingga sangat kental, homogen, daya sebar : 5,8-8,6 cm, daya lekat; 2,19-6,76 detik, viskositas: 3600-18000 cps dan pH: 5,1 – 5,88. Pada formula 1 dihasilkan daya sebar dan daya lekat yang belum memenuhi persyaratan sediaan gel yang baik sedangkan formula 2 dan 3 telah memenuhi semua persyaratan pada hasil uji karakteristik fisik sediaan gel. Oleh karena itu dapat disimpulkan bahwa HPMC dan Karbopol memberikan pengaruh terhadap karakteristik sediaan gel ekstrak etanol daun kirinyuh (C. odorata). Kata Kunci: Kirinyuh, Gel, Karakteristik Fisik         Kirinyuh leaves (Chromolaena odorata L) containing alkaloid, flavonoid, tannin, saponin, anthraquinone, glicoside and terpenoid possess an activity as wound healing empirically. Gel is one of pharmaceutical preparations containing HPMC and Carbopol as gelling agents. It is also cosmetically acceptable, tends to be drying easily, and can be easily removed from the skin. This research aimed to determine the effect of gel of ethanol extract of Kirinyuh leaves (C. odorata) contained various concentrations of gelling agent of HPMC and Carbopol in 3 formulas. Gel was formulated with 0.5% ethanol extract of Kirinyuh leaves (C. odorata) and used variation concentration of gelling agent of HPMC and Carbopol in formula 1, 2 and 3 of 70%:30% ; 50%:50% and 30%:70% respectively. Physical characteristics of gel included organoleptic, homogeneity, spreadability, adhesion, viscosity and pH value were analysed for all formulas. All prepared gels were acceptable in organoleptic tests, homogeneity test, speadibility : 5,8-8,6 cm, adhesion: 2. 19-6.76 sec, viscosity: 3600-18000 cps and pH: 5.1 – 5.88. Spreadibility and adhesion in Formula 1 did not meet al..l of the requirements for good gel formulations while Formula 2 and 3 have met al..l of the requirements. Therefore, it can be concluded that HPMC and Carbopol possess an effect on the physical characteristics of gel of ethanol extract of kirinyuh leaves (C. odorata)
FORMULASI SEDIAAN TABLET EFFERVESCENT DARI EKSTRAK KUNYIT (Curcuma domestica Val.) DENGAN VARIASI JUMLAH ASAM SITRAT-ASAM TARTRAT SEBAGAI SUMBER ASAM Khoerul Anwar
Jurnal Sains dan Terapan Kimia Vol 4, No 2 (2010)
Publisher : Program Studi Kimia, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.074 KB) | DOI: 10.20527/jstk.v4i2.2065

Abstract

Kunyit (Curcuma domestica Val.) merupakan obat tradisional yang banyak digunakan sebagai peluruh haid, penambah nafsu makan, anti radang, memperlancar pengeluaran empedu, dan obat sakit perut. Formulasi dalam bentuk sediaan effervescent diharapkan mempermudah cara penggunaannya. Pada penelitian ini digunakan asam sitrat dan asam tartrat sebagai unsur asam dan diharapkan dapat menghasilkan tablet effervescent ekstrak kunyit dengan sifat fisik yang memenuhi persyaratan.Pembuatan ekstrak kunyit dimulai dengan melakukan soxhletasi menggunakan pelarut petroleum eter dan perkolasi menggunakan pelarut metanol terhadap serbuk kunyit. Tablet effervescent ekstrak kunyit dibuat dalam 5 formula dengan variasi kadar asam sitrat dan asam tartrat. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh variasi jumlah dan jenis unsur asam, yaitu asam sitrat dan asam tartrat, terhadap sifat alir granul yang meliputi waktu alir dan sudut diam, sifat fisik tablet yang meliputi keseragaman bobot, kekerasan, kerapuhan, dan waktu hancur tablet, serta respon terhadap rasa yang dihasilkan.Analisis sifat alir granul dan sifat fisik tablet effervescent dilakukan dengan pendekatan teoritis dan pendekatan statistika dengan uji Anava satu jalan dengan taraf kepercayaan 95% dilanjutkan dengan uji Scheffe. Dari hasil penelitian dapat disimpulkan bahwa asam sitrat memberikan granul dengan waktu alir dan sudut diam yang lebih kecil, serta waktu hancur yang lebih cepat dari asam tartrat. Rasa getir dari kunyit kurang tertutupi karena belum adanya pemanis dan flavoring agent. Kata kunci : kunyit, tablet effervescent, asam sitrat, asam tartrat 
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL, METANOL, DAN AQUADES DARI KULIT BUAH MUNDAR (Garcinia forbesii) Muhammad Ikhwan Rizki; Liling Triyasmono; Khoerul Anwar; Anna Khumaira Sari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.882

Abstract

Mundar (Garcinia forbesii) is a typical plant from South Kalimantan. Mundar pericaps can be used as a natural antioxidant. The use of solvents in the extraction process can affect the antioxidant activity. The purpose of this study was to determine of phytochemical compounds and antioxidant activity of the ethanol, methanol, and aquades extracts from pericaps of mundar (Garcinia forbesii). Mundar pericaps is dried, then made into powder. Mundar pericaps powder was extracted with three different solvents, ethanol 70%, methanol, and aquades. Phytochemical screening and analysis by thin layer chromatography were performed on the three extracts. The three extracts were tested for antioxidant activity by DPPH method. The results showed that ethanol and methanol extracts contained phytochemical compounds of phenolic, flavonoids, tannins, alkaloids, steroids, and terpenoids. Aquades extract contains phenolic, flavonoids, tannins, and alkaloids. The chromatographic profile showed that the ethanol and methanol extracts had an Rf value of 0.307. The antioxidant activity from highest to lowest was ethanol extract (192.64 ppm), methanol extract (236.64 ppm), and aquades extract (443.13 ppm) from mundar pericaps
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL, METANOL, DAN AQUADES DARI KULIT BUAH MUNDAR (Garcinia forbesii) Muhammad Ikhwan Rizki; Liling Triyasmono; Khoerul Anwar; Anna Khumaira Sari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.882

Abstract

Mundar (Garcinia forbesii) is a typical plant from South Kalimantan. Mundar pericaps can be used as a natural antioxidant. The use of solvents in the extraction process can affect the antioxidant activity. The purpose of this study was to determine of phytochemical compounds and antioxidant activity of the ethanol, methanol, and aquades extracts from pericaps of mundar (Garcinia forbesii). Mundar pericaps is dried, then made into powder. Mundar pericaps powder was extracted with three different solvents, ethanol 70%, methanol, and aquades. Phytochemical screening and analysis by thin layer chromatography were performed on the three extracts. The three extracts were tested for antioxidant activity by DPPH method. The results showed that ethanol and methanol extracts contained phytochemical compounds of phenolic, flavonoids, tannins, alkaloids, steroids, and terpenoids. Aquades extract contains phenolic, flavonoids, tannins, and alkaloids. The chromatographic profile showed that the ethanol and methanol extracts had an Rf value of 0.307. The antioxidant activity from highest to lowest was ethanol extract (192.64 ppm), methanol extract (236.64 ppm), and aquades extract (443.13 ppm) from mundar pericaps
APLIKASI SISTEM PAKAR UNTUK DETEKSI KEPRIBADIAN ANAK USIA DINI MEGGUNAKAN FIVE FACTOR MODEL (FMM) BERDASARKAN GESTURE TUBUH ANAK Khoerul Anwar; Randho Bagaskara; Linda Suvi Rahmawati
Prosiding Seminar SeNTIK Vol. 5 No. 1 (2021): Prosiding SeNTIK 2021
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Secara umum orang tua tidak memahami kepribadian anak diusia dini karena anak pada usia dini masih didominasi gestur tubuh bila dibandingkan denganbicara, sehingga orang tua sering salah menerjemahkan gestur tersebut. Oleh karena itu sering didapat informasi terjadi kekerasan terhadap anak.Kesalahan-kesalahan perlakuan/stimulasi pada anak akan berdampak kepada terjadinya gangguan belajar, psikologis bahkan pada kasus tertentu mengakibatkan hilangnya potensi berharga pada diri anak, apalagi dalam bentuk kekerasan. Pada masa pandemi Covid-19 ini menjadi penting kehadiran media digital atau aplikasi yang bisa menterjemahkan gesture tubuh anak usia dini selayaknya seorang ahli tentang perilaku anak yang bisa diakses oleh masyarakat luas. Tantangan yang dihadapi adalah bagaimana menghadirkan aplikasi yang mampu mendeteksi kepribadian anak usia dini dengan akurat dan mudah diakses. Beberapa penelitian telah menghasilkan aplikasi deteksi kepribadian berbasis dekstop ataupun android. Penelitian ini menawarkan aplikasi sistem pakar untuk deteksi kepribadia anak di usia dini berdasarkan Five Factor Model (FFM) Personality. Metode yang digunakan adalah Backward Chaining dengan pelacakan gejala menggunakan Depth First Search (DFS). Hal yang baru pada penelitian ini dibanding penelitian sebelumnya adalah pengembangan pelacakan gejala di node dari model DFS. Tujuan dari penelitian adalah menghadirkan sistem aplikasi deteksi kepribadian anak diusia dini dengan kemampuan seperti seorang pakar kepribadian. Aplikasi ini telah diuji dengan 45 pengujian dan juga telah divalidasi oleh seorang pakar kepribadian dengan tingkat akurasi sistem mencapai 100%.
Membentuk Peserta Didik Menjadi Pribadi Ulul al-bab Prespektif Ma’na-Cum Maghza (Kajian Qs. Ar-Ra’d Ayat 19) Moh. Solikul Hadi; Abdul Kahfi Amrulloh; Khoerul Anwar
Journal of Islamic Scriptures in Non-Arabic Societies Vol. 1 No. 1 (2024): Journal of Islamic Scriptures in Non-Arabic Societies (JISNAS)
Publisher : Kuras Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51214/jisnas.v1i1.772

Abstract

This research explores the formation of students into Ulul al-bab individuals through the Ma'na-Cum Maghza perspective, focusing on the analysis of verse 19 of Surah Ar-Ra'd. The research uses a Quranic studies approach to understand the concept of Ulul al-bab and explore its practical implications in the context of education. Through the interpretation of verse 19, the research identifies factors that support the process of Ulul al-bab's formation and details the implications of Ma'na Cum Maghza in the context of education. The research methodology involves textual and contextual analysis of the verse and an interdisciplinary approach that integrates Islamic educational principles. The results of this study can provide practical guidance for educators in shaping students towards Ulul al-bab individuals through the teachings of the Qur'an and the values of Islamic education. This research has the potential to contribute to a deeper understanding of the development of character and spirituality of students in the context of Islamic education
Co-Authors Abdul Kahfi Amrulloh Amalia Amalia Ana Ulfah Anna Khumaira Sari Aulia Rahmah Evy Setiawati Heri Budi Santoso Liling Triyasmono Linda Suvi Rahmawati Moh. Solikul Hadi Muhammad Ikhwan Rizki Nurlely, Nurlely Prima Happy Ratnapuri Randho Bagaskara Totok Wianto Valentina Meta Srikartika Valentina Meta Srikartika