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All Journal Berkala Kedokteran Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
FX Hendriyono
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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NILAI RUJUKAN HEMATOLOGI ORANG DEWASA NORMAL DI RSUD ULIN BANJARMASIN Azma Rosida; FX Hendriyono
Berkala Kedokteran Vol 11, No 1 (2015)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.712 KB) | DOI: 10.20527/jbk.v11i1.190

Abstract

Results of laboratory tests are interpreted through value. Hematological examination is an examination that is often requested and performed to determine the state of the blood and its components so that the patient's medical condition can be known. Reference value can be obtained from brochure instruments or laboratory has its own research using populations in the laboratory because of possible variation between the laboratory values with other laboratories due to differences in methods of examination and patient characteristics. The objective of the study is to get hematology reference values in Ulin Hospital, Banjarmasin. This study is cross-sectional observasional analytic  study, conducted in hospitals Ulin Banjarmasin, June-July 2014. The subject of the study consisted of 120 women and 120 men who came for medical examinations in clinical pathology laboratories Hospital Ulin, Banjarmasin. Results obtained Hb 12.5-16.7 from the men and women are from 12.0 to 15.6 g / dL. The numbers of male erythrocytes are from 4.1 to 6.0 million / uL and women are 4.0 to 5.3 million / uL. Leukocyte numbers are 4650-10300 / uL. Platelet numbers are 150-356 thousand from men and women are 177-401 thousand / uL. Parameters 75-96 fL MCV, MCH 28-32 pg, MCHC 33-37 g / dL, and RDW-CV 12.1 to 14%. The results of this study did not differ significantly with the reference value that has been used but the obtained values of MCV are lower. Keywords: Reference value, haematology, normal adult,  RSUD Ulin
Efek Jus Buah Karamunting (Melastoma malabathricum L.) Terhadap Kadar Trigliserida Serum Darah Tikus Putih Yang Diinduksi Propiltiourasil Muhammad Ichwan Noorrafiqi; Alfi Yasmin; FX Hendriyono
Berkala Kedokteran Vol 9, No 2 (2013)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i2.952

Abstract

ABSTRACT: This study was aimed to understand the effect of karamunting fruit juice on triglyceride serum level in white rats induced with propylthiouracil (PTU). This study design was experimental, conducted on 7 groups, that is, group I who was not given any treatments (normal group), group II who was given PTU and labelled as negative control, group III who was given PTU and fenofibrate and labelled as positive control, group IV-VII who were given PTU and karamunting fruit juice. Result showed that the average values of triglyceride level in  group VI-VII were 105 mg/dL, 222.75 mg/dL, 85.25 mg/dL, 123 mg/dL, 135.25 mg/dL, 132 mg/dL, and 122.5 mg/dL, respectively. There were significant differences between group II and groups VI-VII who were given karamunting fruit juice. It was concluded that karamunting fruit juice from the dose of 1 mg/gBW could inhibit the increase in triglyceride serum level in white rats induced with PTU and given cholesterol diet. Keywords: karamunting juice, triglyceride, propylthiouracil ABSTRAK: Penelitian ini bertujuan mengetahui efek jus buah karamunting terhadap kadar trigliserida pada tikus putih yang diinduksi propiltiourasil (PTU). Penelitian ini bersifat eksperimental yang dilakukan pada 7 kelompok, yaitu kelompok I yang tidak diberikan perlakuan (kelompok normal), kelompok II yang diberi PTU sebagai kontrol negatif, kelompok III yang diberi PTU dan fenofibrat sebagai kontrol positif, dan kelompok IV-VII yang diberi PTU dan jus buah karamunting. Hasil penelitian menunjukkan rerata kadar trigliserida pada kelompok I-VII berturut-turut adalah sebesar 105 mg/dL, 222,75 mg/dL, 85,25 mg/dL, 123 mg/dL, 135,25 mg/dL, 132 mg/dL, dan 122,5 mg/dL. Terdapat perbedaan bermakna antara kelompok II dan kelompok VI-VII yang diberikan jus buah karamunting. Dapat disimpulkan bahwa jus buah karamunting mulai dosis 1 mg/gBB dapat menghambat peningkatan kadar trigliserida dalam serum darah tikus putih yang diberi pakan kolesterol dan diinduksi PTU. Kata-kata kunci: jus buah karamunting, trigliserida, propiltiourasil
Perbedaan Aktivitas SGPT Sebelum dan Sesudah Kemoterapi Neoadjuvan Penderita Ca Mammae Stadium Lanjut Lokal Subtipe Luminal Murti Fatiya Filayati; FX Hendriyono; Sasongko Hadi Priyono
Homeostasis Vol 3, No 3 (2020)
Publisher : Homeostasis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.934 KB)

Abstract

Abstract: Neoadjuvant chemotherapy is given 3-4 cycles before surgery for locally advanced breast cancer. Aimed at reducing tumour size, killing micrometastases. The purpose was to determine differences in SGPT activity before the first cycle and third cycle of neoadjuvant chemotherapy in patients locally advanced breast cancer luminal subtypes. The research was analytic observational, retrospective cohort method. Sampling with a total sampling technique, data analysis using a paired t-test. Results obtained 18 samples inclusion criteria with median SGPT activity before first cycle of neoadjuvant chemotherapy 13.5U/L with lowest value of 6 U/L highest value of 51 U/L, median SGPT activity before third cycle of neoadjuvant chemotherapy 17.5 U/L lowest value of 9 U/L highest value of 50 U/L. There was a significant difference (p=0.044) SGPT activity before the first cycle and third cycle of neoadjuvant chemotherapy in patients locally advanced breast cancer luminal subtypes in Ulin Hospital Banjarmasin in January-June 2019 period. Keywords: locally advanced breast cáncer, luminal subtype, neoadjuvant chemotherapy, SGPT activity. Abstrak: Kemoterapi neoadjuvan dilakukan sebelum operasi sebanyak 3-4 siklus untuk ca mammae lanjut lokal. Bertujuan memperkecil ukuran tumor dan membunuh mikrometastasis. Tujuan penelitian untuk mengetahui apakah terdapat perbedaan aktivitas SGPT sebelum siklus pertama dan siklus ketiga kemoterapi neoadjuvan pada penderita ca mammae stadium lanjut lokal subtipe luminal. Penelitian bersifat observasional analitik dengan metode Kohort Retrospektif. Penganbilan sampel dengan teknik total sampling dan analisis data menggunakan uji t berpasangan. Hasil penelitian didapatkan 18 sampel yang memenuhi kriteria inklusi dengan median aktivitas SGPT sebelum siklus pertama kemoterapi neoadjuvan 13,5U/L dengan nilai terendah 6 U/L nilai tertinggi 51 U/L, median aktivitas SGPT sebelum siklus ketiga kemoterapi neoadjuvan 17,5 U/L dengan nilai terendah 9 U/L nilai tertinggi 50 U/L. Terdapat perbedaan bermakna (p = 0,044) aktivitas SGPT sebelum siklus pertama dan siklus ketiga kemoterapi neoadjuvan pada penderita ca mammae stadium lanjut lokal subtipe luminal di RSUD Ulin Banjarmasin periode Januari - Juni 2019. Kata-kata kunci:  ca mammae lanjut lokal subtipe luminal, kemoterapi neoadjuvan, aktivitas SGPT
PERBEDAAN KADAR CRP PADA REMAJA TERLATIH DAN TIDAK TERLATIH SETELAH LARI INTENSITAS SEDANG 30 MENIT Raida Namira; Huldani Huldani; Siti Kaidah; Asnawati Asnawati; FX Hendriyono
Homeostasis Vol 6, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i1.8792

Abstract

Aktivitas fisik dapat menimbulkan respons inflamasi. Biomarker inflamasi yang mudah untuk diukur adalah C-reaktif protein. Penelitian ini bertujuan menjelaskan perbedaan kadar CRP sebelum dan setelah lari 30 menit dengan intensitas sedang pada remaja terlatih dan tidak terlatih. Penelitian dilangsungkan melalui Cross Sectional Study pada 15 remaja terlatih yaitu pemain sepak bola dari Klub Perseban Banjarmasin dan 15 remaja tidak terlatih di Banjarmasin yang berkisar umur 16-22 tahun dengan jenis kelamin laki-laki. Teknik pemilihan sampel menggunakan metode purposive sampling. Pengukuran kadar CRP dilakukan sebelum dan setelah lari intensitas sedang 30 menit. Penelitian didapatkan nilai kadar rata-rata CRP 5.3 mg/L pada kelompok remaja terlatih setelah lari intensitas sedang 30 menit dan 11.58 mg/L pada kelompok remaja tidak terlatih setelah lari. Selanjutnya dilakukan uji t tidak berpasangan untuk membandingkan perbedaan (setelah lari) kadar CRP antara 2 kelompok yang dikumpulkan yakni nilai p=0.000 yang menujukkan nampak korelasi berarti. Hasil penelitian ini menyimpulkan bahwa terjadi perbedaan kadar CRP atas remaja terlatih serta tidak terlatih sesudah lari intensitas sedang 30 menit.
Co-Authors Alfi Yasmin Asnawati Asnawati Azma Rosida Huldani Huldani Muhammad Ichwan Noorrafiqi Murti Fatiya Filayati Raida Namira Sasongko Hadi Priyono Siti Kaidah