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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences BIOTROPIA - The Southeast Asian Journal of Tropical Biology ANNALES BOGORIENSES Pharmaceutical Sciences and Research (PSR) JURNAL REKAYASA KIMIA & LINGKUNGAN Annales Bogorienses
Djumali Mangunwidjaja
Departemen Teknologi Industri Pertanian, FTP, Institut Pertanian Bogor
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Engineering Environmental Science Immunology & microbiology Medicine & Pharmacology Veterinary

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Application of Microwave Heating in Biomass Hydrolysis and Pretreatment for Ethanol Production Hermiati, Euis; Mangunwidjaja, Djumali; Sunarti, Ttiti C; Suparno, Ono; Prasetya, Bambang
ANNALES BOGORIENSES Vol 14, No 1 (2010): Annales Bogorienses
Publisher : Research Center for Biotechnology - Indonesian Institute of Sciences (LIPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (505.18 KB) | DOI: 10.1234/33

Abstract

Recently, due to depletion of  fossil derived energy stock in the world, there are growing  interests in utilizing biomass sources of bioethanol. There are basically two types of biomass that are usually used or converted to ethanol, starchy and lignocellulosic biomass. The conversion of starchy and lignocellulosic materials are widely explored,  however,  there  are  still  some  drawbacks,  such  as  high  enzyme  cost  and  intensive  energy  needed. Therefore, lower cost as well as energy and time efficient process technology in biomass conversion to ethanol  is important in enhancing the use of biomass to substitute fossil fuel. Microwave heating offers some advantages to overcome these drawbacks, especially due to its quick heat transfer and its heating selectivity. In conventional heating the  heat  was  transferred  through  conduction  or  convection  process  which  took  longer  time.  Thus,  by using microwave, degradation of starchy and lignocellulosic biomass could be completed in shorter time than by using conventional heating method. The roles of microwave heating in the degradation of biomass, especially starchy and lignocellulosic biomass  and its relation to the hydrolysis and pretreatment of that particular biomass for ethanol production are reviewed and discussed.   Keywords: biomass, pretreatment, ethanol, microwave
Glycerol Utilization as Substrate for Ethanol Production in Escherichia coli Recombinant under an Aerobic Condition Pranata, Wahyu Suradi; Suryadarma, Prayoga; Mangunwidjaja, Djumali
Journal of Tropical Life Science Vol 8, No 1 (2018)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1142.696 KB) | DOI: 10.11594/jtls.08.01.14

Abstract

The utilization of glycerol as a substrate for ethanol production in E. coli recombinant harboring ethanologenic gens (PDC and ADHB) under aerobic conditions was investigated. This research was conducted by using E. coli BW25113 which compared the growth characteristics on glycerol and glucose as carbon source. E. coli can grow well on both substrates and it consumed glycerol faster than glucose. On glucose, E. coli occurred overflow metabolism that indicated by high acetate accumulation. Meanwhile, on substrate of glycerol the acetate accumulation could be reduced. Using glycerol substrate on E. coli increased piruvate accumulation, comparing with glucose. Therefore, the growth characteristic of glycerol was more effective. In E. coli ∆pta/pHfdh/pTadhB-pdc utilized glycerol substrate was able to accumulate pyruvate as intermediate metabolite for produce 2.18 gL-1 ethanol.
Potency of (Poly) Acrylic/Carboxymethyl Starch-Chitosan Biohydrogel for Curcumin Oral Delivery Matrix Ruriani, Eka; Mangunwidjaja, Djumali; Richana, Nur; Sunarti, Titi Candra
Pharmaceutical Sciences and Research Vol. 5, No. 1
Publisher : UI Scholars Hub

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Abstract

Biohydrogel has gathered great interest in the pharmaceuticals field. This natural polymers were biodegradable, non-toxic, biocompatible, and its specific ability to response environment change can be considered for the controlled released matric of bioactive compound. In this study, the biohydrogel was synthesized by graft-copolymerization of acrylic acid onto carboxymethyl starch (CMS) and chitosan. The objective of this research was to determine the effect of CMS-chitosan ratio on the biohydrogel characteristic. The acrylic acid was grafted on to the backbone (3:1) using cerric ammonium nitrate as the inisiator.A standarded curcumin was applied to test the binding potency of matrix. A higher CMS ratio in the polymer mixture (4:1) revealed the highest swelling power (16.9 w/w) and percentage of curcumin absorption (17.34%). All samples have pH-responsive swelling properties, with the swelling trend was observed in the order of distilled water >HCl solution > phosphate buffer solution. FTIR spectra and SEM micrographs has confirmed the graft-copolymerization of PAA/CMSCs biohydrogel by describing the appearance of peak around 1600 cm-1and the morphology of granular structure, respectively. The graft-copolymerization of acrylic acid onto the two anionic natural polymer by cerric ammonium nitrate as the initiator has resulted a pH-dependent swelling biohydrogel, and it has the ability to deliver curcumin in stomach-targeted system.
Adsorpsi Surfaktan Nonionik Alkil Poliglikosida pada Antar muka Fluida-Fluida Adisalamun, Adisalamun; Mangunwidjaja, Djumali; Suryani, Ani; Sunarti, Titi Candra; Arkeman, Yandra
Jurnal Rekayasa Kimia & Lingkungan Vol 9, No 1 (2012): Jurnal Rekayasa Kimia & Lingkungan
Publisher : Chemical Engineering Department, Syiah Kuala University, Banda Aceh, Indonesia

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Abstract

Nonionic surfactants have been used extensively in various industrial applications such as cleaning, personal care, crop protection, paint and coating, textile finishing, emulsion stabilization, food and leather processing. In this study, we have studied the adsorption of three nonionic surfactants of alkyl polyglycoside, namely commercial APG from Cognis and APG produced from glucose as well as APG synthesized from sago starch, at fluidfluid interfaces. The variation of surface and interfacial tension with the concentration of surfactant in the bulk was studied, and the data were fitted using a surface equation of state derived from the Langmuir isotherm. The agreement between ?(c) data and Langmuir isotherm model was very good.Keywords: adsorption, air/water interface, interfacial tension, surface tension
Application of Microwave Heating in Biomass Hydrolysis and Pretreatment for Ethanol Production Hermiati, Euis; Mangunwidjaja, Djumali; Sunarti, Titi C.; Suparno, Ono; Prasetya, Bambang
Annales Bogorienses Vol. 14 No. 1 (2010): Annales Bogorienses
Publisher : BRIN

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Recently, due to depletion of fossil derived energy stock in the world, there are growing interests in utilizing biomass as sources of bioethanol. There are basically two types of biomass that are usually used or converted to ethanol, starchy and lignocellulosic biomass. The conversion of starchy and lignocellulosic materials are widely explored, however, there are still some drawbacks, such as high enzyme cost and intensive energy needed. Therefore, lower cost as well as energy and time efficient process technology in biomass conversion to ethanol is important in enhancing the use of biomass to substitute fossil fuel. Microwave heating offers some advantages to overcome these drawbacks, especially due to its quick heat transfer and its heating selectivity. In conventional heating the heat was transferred through conduction or convection process which took longer time. Thus, by using microwave, degradation of starchy and lignocellulosic biomass could be completed in shorter time than by using conventional heating method. The roles of microwave heating in the degradation of biomass, especially starchy and lignocellulosic biomass and its relation to the hydrolysis and pretreatment of that particular biomass for ethanol production are reviewed and discussed.
Antibreast Cancer Activity of Nanopropolis Indonesia on Induced Mammary Gland Tumor by DMBA in Virgin Sprague-Dawley Rats Hasan, Akhmad Endang Zainal; Mangunwidjaja, Djumali; Sunarti, Titi Candra; Suparno, Ono; Setiyono, Agus
BIOTROPIA Vol. 23 No. 1 (2016): BIOTROPIA Vol. 23 No. 1 June 2016
Publisher : SEAMEO BIOTROP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.285 KB) | DOI: 10.11598/btb.2016.23.1.473

Abstract

The objective of this study was to determine the effect of nanopropolis on DMBA-induced mammary tumors in rats. After the first tumor appearance, twenty-eight rats were divided into seven groups. Groups 1, 2, and 3 served as recipients of nanopropolis treatments at dosages of 8, 32, and 56 μg/mL, respectively. Group 4 received propolis at 233 μg/mL, Group 5 served as the treatment control, Group 6 received DMBA only, and Group 7 served as the normal control. The effects of nanopropolis at 32 μg/mL and propolis at 233 μg/mL were similar in reducing tumor size, healing wounds caused by the tumor, and eliminating cancer cells. Furthermore, the study suggested a relationship between particle size of the absorbent material and its effectiveness. Overall, nanopropolis was very effective in treating mammary gland tumors and breast cancer even at small concentrations.
Co-Authors Adisalamun Adisalamun Agus Setiyono Akhmad Endang Zainal Hasan Anas Miftah Fauzi Ani Suryani Bambang Prasetya EKA RURIANI Euis HERMIATI Khaswar Syamsu Lanjar Sumarno Nastiti Siswi Indrasti Nur Richana Ono Suparno Pranata, Wahyu Suradi Sapta Raharja Sunarti, Ttiti C Titi C. Sunarti Titi Candra Sunarti Yandra Arkeman