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All Journal PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JURNAL FARMASIMED (JFM) Jurnal Buana Farma JURNAL PENGABDIAN MASYARAKAT KOMUNITAS KESEHATAN
Rilyn Novita Maramis
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Jurnal Buana Farma

 1 
AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN NILAM (Pogostemon cablin Benth.) DAN DAUN KEMANGI (Ocimum basilicum L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Rindengan, Elvie Rifke; Gurning, Sri Handayani; Paputungan, Marcelia; Ulaen, Selfie Petronela Joice; Maramis, Rilyn Novita
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1503

Abstract

Infections caused by Staphylococcus aureus bacteria can lead to various health problems, including skin infections that result in redness, swelling, blisters, and pus-filled lumps. The use of herbal plants is an alternative treatment for infections. Plants known to have antibacterial potential include patchouli leaves (Pogostemon cablin Benth.) and basil leaves (Ocimum basilicum L.). This study aims to determine the antibacterial activity of a combination of patchouli leaf extract (Pogostemon cablin Benth.) and basil leaves (Ocimum basilicum L.) against the growth of Staphylococcus aureus bacteria. The type of research used is a laboratory experiment. Extraction of patchouli leaves and basil leaves was performed using the maceration method with 96% ethanol. The test solution was prepared in three concentrations: 10%, 15%, and 20%. The combination was made by mixing each concentration in 1:1 ratio. The antibacterial activity test was conducted using the disc diffusion method, with a positive control consisting of erythromycin discs and a negative control of a 1% Tween 80 solution. Observations were made for 24 hours, then the inhibition zone around the paper disc was measured using a caliper. The combination of patchouli and basil leaf extracts can inhibit the growth of Staphylococcus aureus bacteria.
POTENSI ANTIJAMUR MINYAK ATSIRI DAGING BUAH PALA (Myristica fragrans Houtt) ASAL PULAU SANGIHE PADA Malassezia furfur Nahor, Evelina Maria; Rindengan, Elvie Rifke; Maramis, Rilyn Novita; Rintjap, Djois Sugiaty; Soenjono, Steven Jacob; Kalonio, Donald Emilio
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1513

Abstract

Pityriasis versicolor or tinea versicolor is a skin disease caused by the fungus Malassezia furfur. Nutmeg fruit pulp essential oil contains myristicin compounds that have potential as antimicrobials. The purpose of this study was to determine the antifungal activity of nutmeg fruit pulp essential oil (Myristica fragrans Houtt) from Sangihe Island against Malassezia furfur fungus using the Agar Diffusion and Vapor Phase Test methods. The samples used were nutmeg fruit taken directly from the garden, isolated nutmeg fruit pulp essential oil using the water vapor distillation method. The antifungal activity test for Malassezia furfur used the Agar Diffusion method, using nutmeg oil with concentrations of 20%, 40%, 60%, 80% and 100%, while the antifungal test with the Vapor Phase Test method used nutmeg oil with volumes of 0 μL, 10 μL, 20 μL, 40 μL, 80 μL and 100 μL. Observations were made by measuring the diameter of the clear zone after 24 hours of incubation. The results showed that essential oils of nutmeg fruit flesh at concentrations of 20%, 40%, 60%, 80% and 100% using the Agar Diffusion method were able to inhibit the growth of Malassesia furfur fungus, while with the Vapor Phase Test method the antifungal activity of essential oils of nutmeg fruit flesh was at test volumes of 40 μL, 80 μL and 100 μL.
Co-Authors Djois Sugiaty Rintjap Dumanauw, Jovie Mien ELVIE RIFKE RINDENGAN, ELVIE RIFKE Gurning, Sri Handayani Kalonio, Donald Emilio Nahor, Evelina Maria Paputungan, Marcelia Soenjono, Steven Jacob Suleman, Nurningsih Ulaen, Selfie Petronela Joice Yos Banne