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Journal : JURNAL ILMIAH SIMANTEK

EFEKTIFITAS EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA NESS) DENGAN KLORAMFENIKOL TERHADAP PERTUMBUHAN BAKTERI SALMONELLA TYPHI SECARA IN VITRO FAJAR MUHAMMAD NASUTION; MUHAMMAD JALALUDDIN ASSUYUTHI CHALIL; ANNISA .; MELVIANA LUBIS
JURNAL ILMIAH SIMANTEK Vol 3 No 3 (2019): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

S. typhi is a stem bacteria, and gram-negative bacteria causes of typhid fever that until now became a health problem . Sambiloto (Andrographis paniculata Ness) is a potentially medicinal plants because it has antibiotic effect on bacteria. Objective: This study aims to determine the effectiveness of sambiloto’s leaf ectract on Salmonella typhi growth in vitro. Method: this research use experimental method. The technique used in measuring antibiotic activity is the method of disk diffusion. Result: The result showed that the sambiloto’s leaf extract (Andrographis paniculata Ness) with concentration of 80%, 40%, 20% and 10% yielded the mean of clear zone diameter ie 9.93 mm, 9.61 mm, 8.74 mm, and 7.49 mm. in this study showed that each concentration has different inhibitory power between the one with the other which obtained the value (p<0.05) but in the concentration ratio of 40% with 80% obtained value (p>0.05). Conclusion: Sambiloto’s leaf extract has an inhibitory power to the growth of Salmonella typhi bacteria and it can be seen in the result of the study. The higher the concentration of sambiloto’s leaf extract given, more higher the clear zone forme on the agar medium.
HUBUNGAN KUANTITAS TIDUR DENGAN TINGKAT KONSENTRASI PADA MAHASISWA STAMBUK 2014 FAKULTAS KEDOKTERAN UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA PADA TAHUN 2017 HUDDY ARTICA SINULINGGA; MELVIANA .; GUSBAKTI RUSIP; ANITA SURYA
JURNAL ILMIAH SIMANTEK Vol 3 No 3 (2019): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Sleep affects the ability to concentrate, speak, understand what we are reading, and conclude what we are hearing. If the sleep is disturbed, then it also disturbed mood, body functions and social relationships with people around. The concentration and understanding of a person are influenced by serotonin neurotransmitters whose concentration will decrease if lack of sleep. Therefore, to obtain adequate and balanced serotonin concentrations, an adequate quantity of sleep is required. Objective: the purpose of study is to determine the relationship of quantity of sleep with the level of concentration at student class of 2014. Method: analytical descriptive with the cross sectional design. A total of 96 respondents were selected with total sampling technique. Sleep quantity data were taken using the Pittsburgh quality sleep index (PSQI) and the concentration level of the Stroop test. At the end of the research, Gamma statistical test was done to find out the relationship between the two variables.Results:statistic analysis using spearman test, n =96, p = 0,001 (p <0,05), and r =0944.Conclusion: in this research, there is a correlation between quantity of sleep with the level of concentration at student class of 2014, in Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara.
PERBANDINGAN DAYA HAMBAT EKSTRAK DAUN KAYU MANIS (CINNAMOMUM BURMANNII) KONSENTRASI 10% DAN 20% TERHADAP PERTUMBUHAN JAMUR DERMATOFITA PADA PASIEN TINEA KORPORIS SECARA IN VITRO FITRI DYANA SIAGIAN; MELVIANA LUBIS
JURNAL ILMIAH SIMANTEK Vol 4 No 4 (2020): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Dermatophytosis is one of the superficial dermatomycosis groups caused by dermatophyte fungal infections of the skin,occurring as a reaction of the host to fungal metabolite products and due to invasion by an organism in a living tissue.Cinnamomum burmannii leaves have an antifungal effect on fungi. Flavonnoids, saponins, alkaloids, and tannins on theleaves of cinnamon are known to inhibit dermatophytic fungi. This type of research is an experimental research because inthis study the treatment was carried out, namely the administration of cinnamon leaf extract (Cinnamomun burmannii) with aconcentration of 10% and 20% and then the effect on the growth of dermatophytic fungi will be seen. This study uses a staticgroup comparative research method (Static Group Comparison) that is by making measurements (observations) made afterthe treatment group accepts the program or intervention. From the results of the study showed that the leaves of cinnamon(Cinnamomum burmannii) with a concentration of 10% and 20% can inhibit the growth of Microsporum sp. In the fourthpatient. Cinnamomun burmannii leaf extract with a concentration of 10% and 20% has the ability as an antifungal to thegrowth of microsporum sp. in the fourth patient and cinnamon burmannii leaf extract 20% concentration was the mosteffective in inhibiting the growth of microsporum sp. (highest clear zone).