Claim Missing Document
Check
Articles

Found 4 Documents
Search

Jamu formula could reduce plasma cholesterol patients with mild Hypercholesterolemia Zuraida Zulkarnain; Agus Triyono; Fajar Novianto
Health Science Journal of Indonesia Vol 9 No 2 (2018)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/hsji.v9i2.808

Abstract

Latar belakang: Pengobatan hiperkolesterolemia sering berlangsung seumur hidup sehingga menyebabkanpenderita meninggalkan obat kimia dan memilih obat herbal. Penelitian ini merupakan uji klinik yang bertujuanuntuk mengetahui khasiat dari formula jamu antikolesterol yang terdiri dari daun jati belanda, daun jati cina,daun tempuyung, daun teh hijau, rimpang temulawak, rimpang kunyit dan herba meniran dalam menurunkankadar kolesterol darah sebagai bagian dari program Saintifikasi Jamu. Metode: Penelitian ini menggunakan metode kuasi eksperimental dengan desain pre dan post. Jumlah subjek50 pasien dengan hiperkolesterolemia ringan yang memenuhi kriteria inklusi. Penelitian dilakukan di RumahRiset Jamu (RRJ) Hortus Medicus Tawangmangu pada bulan September sampai Desember 2014. Uji statistikyang digunakan adalah uji t berpasangan dengan bantuan program SPSS 16. Hasil: Formula jamu antihiperkolesterol yang diminum setiap hari selama 28 hari mampu menurunkan rataratakadar kolesterol plasma subjek dari 212.42 mg / dl menjadi 196.6 mg / dl. Uji t test berpasangan didapatkanhasil p<0,05 yang berarti ada perbedaan rerata kadar kolesterol sebelum dan sesudah pemberian jamu.Kesimpulan: Formula jamu antihiperkolesterol mampu menurunkan kadar kolesterol plasma pasiendengan hiperkolesterolemia ringan pada pemberian selama 28 hari. (Health Science Journal of Indonesia2018;9(2):87-92) Kata kunci: hiperkosterolemia, jamu, saintifikasi jamu Abstract Background: Treatment of hypercholesterolemia often lasts a lifetime, therefore patients leavechemical drugs and choose herbal medicines. The aim of this clinical study is to evaluate the efficacy ofantihiperkolesterol jamu formula consists of Guazuma ulmifolia leaves, Cassia senna leaves, Sonchusarvensis leaves, Camellia sinensis leaves, Curcuma xanthorrhiza rhizomes, Curcuma longa rhizomes andPhyllanthus niruri herbs to lowering cholesterol plasma level as part of Saintifikasi Jamu program. Methods: This study was a quasi-experimental with pre and post test design. The total subjects were 50patients with mild hypercholesterolemia who met the inclusion criteria. The research took place at RRJ‘Hortus Medicus’ Tawangmangu between September to December 2014. The data were analyzed using apaired t-test with SPSS 16 software. Results: Results showed jamu anticholesterol formula which is taken every day for 28 days lowered themean of cholesterol plasma level of 212.42 mg / dl to 196.6 mg / dl. Paired t test at 95% confidence levelacquired p value <0.05, showed that there is significant differences in the mean cholesterol level subjectsbefore and after the study. Conclusion: The administration of jamu antihypercholesterol formula for 28 days could reduce plasmacholesterol level in subjects with mild hypercholesterolemia. (Health Science Journal of Indonesia2018;9(2):87-92) Keywords: hypercholesterolemia, Jamu, Saintifikasi Jamu
PENGARUH PEMBERIAN JAMU ANTI FIBRO ADENOMA MAMMAE TERHADAP FUNGSI GINJAL DI RUMAH RISET JAMU (RRJ) ‘HORTUS MEDICUS’ Zuraida Zulkarnain; Ulfatun Nisa; Ulfa Fitriani; Enggar Wijayanti
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Perkembangan Terbaru Pemanfaatan Herbal Sebagai Agen Preventif Pada Tera
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.008 KB) | DOI: 10.31942/jiffk.v0i0.1205

Abstract

ABSTRAK Fibro Adenoma Mammae (FAM) merupakan tumor jinak kelenjar mammae (payudara) yang paling sering dijumpai pada wanita. Sebagian penderita FAM mencari pengobatan alternatif dengan meminum formula jamu yang dianggap memiliki khasiat anti tumor karena takut atau tidak punya biaya untuk operasi.  Formula jamu ini harus diminum rutin dan dalam jangka waktu lama. Penelitian ini bertujuan untuk mengetahui pengaruh formula jamu anti FAM yang terdiri dari temu mangga  15 gram, daun teh hijau  7 gram, benalu  8 gram, kunir putih 10 gram, bidara upas 5 gram terhadap kadar ureum dan kreatinin plasma sebagai parameter fungsi ginjal. Penelitian dilakukan pada tahun 2013 dengan desain pre dan post test. Subyek penelitian adalah pasien dengan diagnosis FAM yang memenuhi kriteria inklusi dan eksklusi yang datang dan berobat di RRJ ‘Hortus Medikus’ Tawangmangu dengan jumlah sampel 26 orang. Subyek diharuskan meminum formula jamu tersebut di atas setiap hari selama 4 bulan. Data penelitian diolah menggunakan uji p berpasangan dengan bantuan SPSS for windows versi 16. Hasil penelitian didapatkan tidak terdapat perbedaan bermakna kadar ureum dan kreatinin pada awal dan akhir penelitian (p>0.05). Dapat disimpulkan bahwa formula jamu anti FAM tidak mengubah atau mengganggu fungsi ginjal pada konsumsi rutin setiap hari selama 4 bulan. Kata Kunci : FAM, formula jamu, fungsi ginjal
EFEK PEMBERIAN KAPSUL EKSTRAK JAMU HIPERGLIKEMI TERHADAP KUALITAS HIDUP: The Effect of Hyperglycemic Herbal Extract Capsules on Quality of Life Ulfa Fitriani; Agus Triyono; Danang Ardiyanto; Zuraida Zulkarnain; Peristiwan Ridha Widhi Astana; Ulfatun Nisa; Fajar Novianto; Enggar Wijayanti
Jurnal Tumbuhan Obat Indonesia Vol. 16 No. 1 (2023): July 2023
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v16i1.600

Abstract

Quality of Life (QoL) in diabetes mellitus (DM) has become highly emphasized in recent years as health care outcome. Hyperglicemic herbs potio, one of scientific herbs, has been proven to be safe and efficacious. The use of extract capsules as an innovative form of herbal medicine continues to be developed. The study aimed to examine the effect of giving hyperglicemic herbal extract capsules on the QoL of hyperglycemic patients at Rumah Riset Jamu (RRJ) Hortus Medicus. The method used was pre and post-test design with quasi-experimental. A total of 60 patients followed the study during September-November 2019. The hyperglycemic herbs formula consisting of 5 grams daun Salam, 5 grams sambiloto, 7 grams kayu manis and 10 grams temulawak which converted to the one extract capsule. For the daily doses are two capsules twice a day. The Metformin 500 mg single dose as a control of the study. Before this study and on day 28th, the patients had been examined the QoL using the short form-36 (SF-36). The data were analyzed using the Wilcoxon and Mann Whitney test. The results showed that there was a significant increase in total score of SF-36 (p=0,000) between before and after taking extract capsules, especially for the general health domain (p=0,002). The total score of SF-36 between extract capsules and Metformin groups was not significantly difference (p=0,323). Hyperglycemic herbal extract capsules improved the QoL of the hyperglycemic patients.
EFEK PEMBERIAN KAPSUL EKSTRAK JAMU HIPERGLIKEMI TERHADAP KUALITAS HIDUP: The Effect of Hyperglycemic Herbal Extract Capsules on Quality of Life Ulfa Fitriani; Agus Triyono; Danang Ardiyanto; Zuraida Zulkarnain; Peristiwan Ridha Widhi Astana; Ulfatun Nisa; Fajar Novianto; Enggar Wijayanti
Jurnal Tumbuhan Obat Indonesia Vol. 16 No. 1 (2023): July 2023
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v16i1.600

Abstract

Quality of Life (QoL) in diabetes mellitus (DM) has become highly emphasized in recent years as health care outcome. Hyperglicemic herbs potio, one of scientific herbs, has been proven to be safe and efficacious. The use of extract capsules as an innovative form of herbal medicine continues to be developed. The study aimed to examine the effect of giving hyperglicemic herbal extract capsules on the QoL of hyperglycemic patients at Rumah Riset Jamu (RRJ) Hortus Medicus. The method used was pre and post-test design with quasi-experimental. A total of 60 patients followed the study during September-November 2019. The hyperglycemic herbs formula consisting of 5 grams daun Salam, 5 grams sambiloto, 7 grams kayu manis and 10 grams temulawak which converted to the one extract capsule. For the daily doses are two capsules twice a day. The Metformin 500 mg single dose as a control of the study. Before this study and on day 28th, the patients had been examined the QoL using the short form-36 (SF-36). The data were analyzed using the Wilcoxon and Mann Whitney test. The results showed that there was a significant increase in total score of SF-36 (p=0,000) between before and after taking extract capsules, especially for the general health domain (p=0,002). The total score of SF-36 between extract capsules and Metformin groups was not significantly difference (p=0,323). Hyperglycemic herbal extract capsules improved the QoL of the hyperglycemic patients.