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All Journal Jurnal Anestesi Perioperatif Bali Journal of Anesthesiology Majalah Anestesia dan Critical Care Majalah Kedokteran Andalas The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Arif H. M. Marsaban
Departemen Anestesiologi Dan Intensive Care Fakultas Kedokteran Universitas Indonesia/RSUPN Cipto Mangunkusumo
Education Health Professions Medicine & Pharmacology Public Health Other

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Efektivitas Pemberian Cairan Praoperatif Ringer Laktat 2 mL/kgBB/jam Puasa untuk Mencegah Mual Muntah Pascaoperasi Wijaya, Andi Ade; Fithrah, Bona A.; Marsaban, Arif H. M.; Hidayat, Jefferson
Jurnal Anestesi Perioperatif Vol 2, No 3 (2014)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Teknik nonfarmakologi yang dapat dilakukan untuk menurunkan angka kejadian mual muntah pascaoperasi adalah pemberian cairan praoperatif. Tujuan penelitian ini untuk mengetahui efektivitas pemberian cairan praoperatif Ringer laktat 2 mL/kgBB/jam puasa untuk menurunkan angka kejadian mual muntah pascamastektomi. Penelitian ini merupakan uji klinis acak yang dilakukan pada bulan Maret–April 2013 di Rumah Sakit Kanker Dharmais, Rumah Sakit Persahabatan, Rumah Sakit Fatmawati, dan Rumah Sakit Cipto Mangunkusumo Jakarta, pada pasien status fisik American Society of Anesthesiologist (ASA) 1–2. Sebanyak 102 pasien diacak ke dalam kelompok hidrasi dan kelompok kontrol. Analisis data dilakukan menggunakan uji chi-kuadrat. Terdapat perbedaan yang signifikan dalam kejadian mual pada 0–1 jam pascaoperasi (kelompok hidrasi 20% vs kelompok kontrol 39%) dan pada 0–24 jam pascaoperasi (kelompok hidrasi 22% vs kelompok kontrol 41%). Walaupun tidak berbeda secara statistik, angka kekerapan mual pada 1–24 jam pascaoperasi lebih rendah pada kelompok hidrasi 12% (6) dibandingkan dengan kelompok kontrol 23% (12). Tidak ada perbedaan secara statistik pada angka kekerapan muntah di kedua kelompok penelitian. Pemberian cairan praoperatif Ringer laktat 2 mL/kgBB/jam puasa efektif untuk menurunkan angka kejadian mual pascaoperasi mastektomi pada 1 jam pertama pascaoperasi.  Kata kunci: Cairan praoperatif, mastektomi, mual muntah pascaoperasi Effectiveness of Pre-operative Lactated Ringer’s Solution 2 mL/kgBW/h in Fasting Patients to Prevent Post-operative Nausea and Vomiting Non pharmacologic approaches to overcome post operative nausea and vomiting include giving pre-operative hydration. The objective of this study was to learn the efficacy of pre-operative lactated Ringer’s solution (2 mL/kgBW/hour) in fasting patients to overcome the post-operative nausea and vomiting in mastectomy surgery. This study was a randomized clinical trial that conducted in March to April 2013 in Dharmais Hospital-National Cancer Center,  Persahabatan Hospital, Fatmawati Hospital, and Rumah Sakit Cipto Mangunkusumo Jakarta to patients with  American Society of Anesthesiologist (ASA) physical status 1–2. A total of 102 patients were randomized into the hydration group and control group. Data analysis was performed using chi-square test or appropriate test using SPSS ver. 15. There were statistically significant differences in the incidence of nausea at 0–1 hour post-operative (19.6% in hydration group vs. 39.2% in control group) and at 0–24 hours post-operative (21.6% in hydration group vs. 41.2% control group). The incidence of 1–24 hours PONV, although not statistically significant, was higher in the control group (11.8% in hydration group vs. 23.5% in control group). There was no difference in vomiting incidence between the two groups. Pre-operative lactated Ringer’s solution 2 mL/kgBW/hour in fasting patients effectively reduces the incidence of post-operative nausea one hour after operation. Key words: Mastectomy, post-operative nausea and vomiting pre-operative hydration DOI: 10.15851/jap.v2n3.332
Deksametason Intravena dalam Mengurangi Insidens Nyeri Tenggorok Pascabedah Wijaya, Andi Ade; Garditya, Rama; Marsaban, Arif H. M.
Jurnal Anestesi Perioperatif Vol 3, No 2 (2015)
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Anestesia umum dengan pipa endotrakeal digunakan untuk memberikan ventilasi tekanan positif dan mencegah aspirasi, namun penggunaannya dapat menimbulkan komplikasi nyeri tenggorok pascabedah. Penelitian ini dilakukan membandingkan efektivitas deksametason intravena dengan triamsinolon asetonid topikal dalam mengurangi nyeri tenggorok pascabedah. Penelitian ini merupakan uji klinis acak tersamar ganda yang dilakukan selama bulan Maret–April 2013 di Rumah Sakit Cipto Mangunkusumo pada pasien yang menjalani pembedahan dalam anestesia umum menggunakan pipa endotrakeal. Subjek dibagi menjadi dua kelompok, kelompok deksametason sebanyak 61 orang dan kelompok triamsinolon sebanyak 60 orang. Sebelum induksi, pasien dalam grup deksametason diberikan 10 mg deksametason intravena dan pasta plasebo dioleskan pada balon pipa endotrakeal. Pasien dalam grup triamsinolon diberikan 2 mL NaCl 0,9% intravena dan pasta triamsinolon asetonid dioleskan pada balon pipa endotrakeal. Skor nyeri tenggorok pascabedah dievaluasi sesaat setelah pembedahan berakhir, 2 jam dan 24 jam pascabedah. Hasil penelitian, tidak didapatkan perbedaan bermakna pada kedua kelompok  kejadian nyeri tenggorok pascabedah sesaat setelah pembedahan berakhir (27,9% pada kelompok A dan 18,3% pada kelompok B, p=0,214). Triamsinolon asetonid topikal memiliki efektivitas yang sama dengan deksametason intravena dalam mengurangi insidens nyeri tenggorok pascabedah.  Kata kunci:  Deksametason, intubasi endotrakeal, nyeri tenggorok pascabedah, pasta triamsinolon asetonidComparison between Topical Triamcinolone Acetonide and Intravenous Dexamethasone in Reducing Postoperative Sore Throat IncidenceTracheal intubation is often used to give positive-pressure ventilation and prevent aspiration during general anesthesia. However, the use of this airway device can cause postoperative sore throat (POST). This study was conducted to compare the effectiveness of prophylactic intravenous dexamethasone and triamcinolone acetonide paste in reducing POST. This study was a double-blind randomized clinical trial conducted during April–May 2013 in Cipto Mangunkusumo General Hospital on patients scheduled for surgery under general anesthesia using endotracheal tube. Subjects were randomly allocated into two groups; 61 patients in dexamethasone group and 60 patients in triamcinolone group. Before induction, the dexamethasone group received 10 mg of intravenous dexamethasone and placebo paste on the endotracheal tube cuff. Triamcinolone group received 2 mL of intravenous normal saline and triamcinolone acetonide paste on the endotracheal tube cuff. POST scores were evaluated immediately after the operation, 2-hours, and 24-hours after the operation. There was no significant difference in the incidence of POST immediately after the operation between the two groups (27.9% in group dexamethasone vs 18.3% in group triamcinolone, p=0.214). Topical triamcinolone acetonide is equally effective compared to prophylactic intravenous dexamethasone in reducing the incidence of POST.  Key words: Dexamethasone, endotracheal intubation, posts operative sore throat, triamcinolone acetonide paste
Effectiveness of Partial and Adjustment Neostigmine Dose as a Neuromuscular Reversal for Single Dose Rocuronium Hidayat, Jefferson; Marsaban, Arif HM; Daryono, Maria Veronica Tita Ekaputri Hadi
Bali Journal of Anesthesiology Vol 2, No 1 (2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bjoa.v2i1.62

Abstract

Background: Routine reversal (neostigmine) and the use of quantitative monitoring of neuromuscular blockade (Train of Four Ratio (TOFR)) are recommended to prevent the occurrence of residual paralysis. This study attempted to determine the effectiveness between neostigmine partial dose 0.02 mg/kgbw and adjusted dose based on TOFR value in recovering neuromuscular blockade of single dose rocuronium 0.6 mg/kgbw.Methods: This randomized clinical trial was performed in the operating room of Integrated Surgical Care Unit of Cipto Mangunkusumo General Hospital and Kirana Clinic. Sixty-one patients who underwent elective surgery in general anesthesia were randomized in to 2 groups: administration of neostigmine in partial dose 0.02 mg/kgbw (group A) and adjusted dose based on TOFR value (group B). Quantitative monitoring evaluation of neuromuscular blockade was performed four times: after adequate spontaneous breathing, 5, 10, and 15 minutes after reversal.Result: The mean of TOFR values in group A and group B respectively: after spontaneous breathing 42% and 50% (p=0.436); 5 minutes after reversal 80.2% and 89.2% (p=0.083); 10 minutes after reversal 92.2% and 94% (p=0.399); 15 minutes after reversal 94.3% and 94.9% (p=0.526). After the 5 minutes of reversal, group B (80.6%) reaches TOFR value ≥ 90% many more than group A (63.3%) (p=0.132).Conclusion: Neostigmine partial dose 0.02 mg/kgbw was as effective as administering neostigmine in adjustment dose based on TOFR values to achieve complete recovery from the neuromuscular block effect of single-dose rocuronium 0.6 mg/kgbw. This study also show the complete recovery of neuromuscular block when TOFR value ≥ 90%.
Mual Muntah Pasien Pascavitrektomi: Perbedaan Rumatan Kombinasi Sevofluran 1,2%-Fentanil 1,2 μg/kgBB/jam dengan Rumatan Sevofluran 2% Marsaban, Arif H. M.; Kapuangan, Christopher; Yulian, Anggadria Iqbal
Jurnal Anestesi Perioperatif Vol 5, No 1 (2017)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (700.098 KB) | DOI: 10.15851/jap.v5n1.996

Abstract

Vitrektomi merupakan operasi yang sering dilakukan dengan insidens mual muntah pascaoperatif yang cukup tinggi. Kombinasi opioid - anestetik inhalasi merupakan pilihan dalam rumatan anestesia umum karena mempunyai efek sinergis. Perbandingan dosis kombinasi fentanil dan sevofluran dengan timbulnya efek samping mual muntah pascaoperatif belum pernah dilaporkan. Penelitian ini bertujuan mengetahui perbedaan insidens mual muntah pascavitrektomi antara rumatan kombinasi sevofluran 1,2%- fentanil 1,2 μg/kgBB/jam dan sevofluran 2%. Penelitian ini merupakan uji klinis acak tersamar tunggal terhadap pasien yang menjalani vitrektomi dengan anestesia umum di Ruang operasi mata Kirana RSUPN Cipto Mangunkusumo Jakarta Mei–Juli 2015. Enam puluh dua pasien yang akan menjalani vitrektomi dengan anestesia umum dirandomisasi ke dalam dua kelompok, yaitu kelompok yang mendapat rumatan kombinasi sevofluran 1,2%-fentanil 1,2 μg/kgBB/jam dan kelompok dengan rumatan sevofluran 2%. Pengukuran mual muntah pascabedah dilakukan dengan metode wawancara langsung. Analisis data dilakukan dengan uji chi-kuadrat dan uji Fisher sebagai uji alternatif. Insidens mual antara kedua kelompok berbeda bermakna pada periode 0–2 jam pascaoperasi (p<0,05), sedangkan pada periode 2–6 jam, insidens mual antara kedua kelompok tidak berbeda bermakna (p>0,05). Simpulan, rumatan anestesia dengan sevofluran 1,2%-fentanil 1,2 μg/kgBB/jam menimbulkan insidens mual dalam 2 jam pertama pascavitrektomi yang lebih rendah dibanding dengan sevofluran 2%.Kata kunci: Fentanil, mual muntah pascavitrektomi, sevoflurane Anesthesia for vitrectomy patient has a high incidence of postoperative nausea and vomiting (PONV).Combination of opioid and inhalation anesthesias has been commonly used for anesthesia maintenance  due to their sinergystic effect. The effect of fentanyl-sevoflurane dosage to PONV incidence in vitrectomy surgery has never been studied. This study aimed to determine the difference in PONV incidence between combination of sevoflurane 1.2%-fentanyl 1.2 μg/kgBW/hour and sevoflurane 2% for anesthesia maintenance. This study was a single blind randomized study in vitrectomy patients with general anesthesia at Kirana Operating Theatre of Dr.Cipto Mangunkusumo National General Hospital during May–July 2015. Sixty two patients who were undergoing vitrectomy surgery with general anesthesia were randomized into sevofluran 1.2%- fentanil 1.2 μg/kgBW/hour group and sevoflurane 2% group. Postoperatively, the incidences of PONV were recorded. Data were collected by anamnesis method and analyzed by chi-square and Fisher test. There was a significant difference of nausea incidence between the two intervention groups within 0–2 hours postvitrectomy period (p<0.05) but no significant difference within 2–6 hours postvitrectomy period (p>0.05). In conclusion, sevoflurane 1.2%-fentanyl 1.2 μg/kgBW/hour has lower incidence of postvitrectomy nausea within the first 2 hour compared to sevoflurane 2%.Key words: Fentanyl, postvitrectomy nausea and vomiting, sevoflurane 
Pengaruh Edukasi Pra-anestesia terhadap Tingkat Kecemasan Pasien Dewasa yang Menjalani Operasi Jantung Terbuka Marsaban, Arif H. M.; Hidayat, Jefferson; Kusumadewi, Irmia; Nainggolan, Gina Adriana
Majalah Anestesia dan Critical Care Vol 34 No 3 (2016): Oktober
Publisher : Perdatin Pusat

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Abstract

Kecemasan praoperasi mengaktifkan stres respon&nbsp; yang menyebabkan stimulasi sistem saraf simpatis (menstimulasi sistem kardiovaskular dengan meningkatkan jumlah katekolamin darah yang menyebabkan takikardi, hipertensi, iskemik dan infark miokardial). Respon tersebut merugikan sirkulasi koroner, menyebabkan peningkatan morbiditas dan mortalitas. Salah satu penanganannya adalah dengan pemberian informasi (edukasi), melalui komunikasi efektif, informatif dan empati, diharapkan terjadi penurunan tingkat kecemasan pasien sebelummenjalani pembiusan dan pembedahan. Penelitian ini menginvestigasi pengaruh edukasi pra-anestesia terhadap tingkat kecemasan pasien operasi jantung terbuka di RSUPN Cipto Mangunkusumo. Penelitian ini menggunakan uji kuasi eksperimen pada pasien operasi jantung terbuka dewasa di Instalasi PJT RSUPN Cipto Mangunkusumo pada bulan Maret 2016. Setelah mendapatkan ijin komite medik dan informed consent, pada 36 subyek dilakukan penilaian tingkat kecemasan sebelum dan sesudah edukasi dengan menggunakan instrumen APAIS. Sebelumedukasi dilakukan pengukuran tanda vital, dilanjutkan dengan pemberian edukasi dan diskusi. Terdapat penurunan bermakna rerata tingkat kecemasan sebelum edukasi dibandingkan dengan sesudah edukasi (p&lt;0,001). Edukasi pra-anestesia menurunkan tingkat kecemasan pasien dewasa yang akan menjalani operasi jantung terbuka di Instalasi PJT RSUPN Cipto Mangunkusumo. Kata kunci: Edukasi, komunikasi efektif, tingkat kecemasan, operasi jantung terbuka The Effect of Education on the Anxiety Level of Adults Patient Undergoing Open Heart Surgery Pre-operative anxiety activates the stress response, causing stimulation of the sympathetic nervous system, which timulates cardiovascular system by increasing the blood catecholamines levels, causing tachycardia, hypertension, ischemia and myocardial infarction. The response may have detrimental effects on the coronary circulation, increasing morbidity and mortality. One of the management is by the provision of information (education) through effective and informative communication with empathy, which are expected to decrease patients’ anxiety level before undergoing anesthesia and surgery. This study aimed to determine the effect of preanesthesia education to the anxiety level in open heart surgery patients in Cipto Mangunkusumo Hospital. This was a quasi-experimental trials of adult open heart surgery patients in Integrated Cardiac Center of Cipto Mangunkusumo Hospital in March 2016. After permission from the medical committee and informed consent were obtained, the anxiety level of 36 subjects was assessed before and after the education using APAIS instrument. Before the education was given, vital signs were measured, continued by education and discussion. There was a significant decrease in the average level of anxiety before education compared with after education (p&lt;0.001). Preanesthesia education lowers the anxiety level in adult open heart surgery patients in Cipto Mangunkusumo Hospital. Key words: Education, effective communication, the level of anxiety, opens heart surgery
Perbandingan Kemudahan Pemasangan Laryngeal Mask Airway antara Teknik Baku disertai Penekanan Lidah dengan Teknik Baku Marsaban, Arif HM; Martaria, Nency; Firdaus, Riyadh; Cahyadi, Arief
Majalah Anestesia dan Critical Care Vol 32 No 3 (2014): Oktober
Publisher : Perdatin Pusat

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Abstract

Laryngeal mask airway (LMA) merupakan suatu alat bantu jalan napas. Teknik baku pemasangan LMA disertai penekanan lidah memberikan angka keberhasilan pemasangan 100%. Penelitian ini bertujuan membandingan kemudahan dan komplikasi pemasangan LMA menggunakan teknik baku dengan penekanan lidah dibandingkan dengan teknik baku. Penelitian ini merupakan studi uji klinis acak tersamar tunggal yang dilakukan antara Mei – Juni 2013 di RSCM, pada 80 pasien dewasa yang menjalani operasi elektif dengan anestesia umum menggunakan LMA. Pada 40 pasien mengalami pemasangan LMA dengan teknik baku disertai penekanan lidah dan 40 pasien dengan teknik baku. Upaya pemasangan dan kemudahan dicatat dan dinilai. Pemasangan mudah bila ≤2 kali. Komplikasi pemasangan berupa noda darah, nyeri menelan dan nyeri tenggorokan dicatat dan dinilai. Analisis statistik dilakukan dengan uji chi-kuadrat dan eksak fisher. Batas kemaknaan untuk semua uji adalah p &lt;0,05. Perbandingan proporsi keberhasilan upaya pemasangan pertama dan kedua antara kelompok teknik baku disertai penekanan lidah dan teknik baku adalah 87,5% banding 65% dan 100% banding 97,5%, secara berurutan. Pemasangan LMA dengan teknik baku disertai penekanan lidah tidak lebih mudah dibanding dengan teknik baku. Kekerapan komplikasi yang berbeda bermakna berupa noda darah 0% pada teknik baku disertai penekanan lidah dan 6,2% pada teknik baku. Kata kunci: Kemudahan pemasangan, komplikasi, laryngeal mask airway, teknik baku disertai penekanan lidah, teknik baku LMA is one of the airway management device. Novel technique of LMA insertion combined with tongue supression technique resulted in 100% succes rate of insertion. The objective of this study was to compare easiness and complications of inserting LMA using classic approach combined with tongue supression and classic approach. This study was a single-blind randomized clinical trial conducted from May ̶June 2013 in RSCM on 80 adult patients who underwent elective surgery with general anesthesia using LMA. In 40 patients underwent LMA insertion with classic approached combined with tongue supression technique and 40 patients with classic approached. Effort and success rate was noted and evaluated. Insertion was considered easy if the insertion was attempted maximally twice. Complications such as blood stains, sore throat, and dysphagia was noted and evaluated. Statistical analysis conducted by Chi-square Test and Fischer Exact. P &lt;0,05 was considered significant. Proportion of first and second attempt LMA insertion between both technique was 87,5% compared with 65% and 100% compared with 97,5%, respectively. LMA insertion with classic approached combined with tongue supression technique was not easier than with classic approached technique. Complication which statistically significant different was blood stains 0% with classic approached combined with tongue supression technique compared with 6,2% classic approached technique. Key words: Classic approached combined with tongue supression, classic approached technique easy installation complications, laryngeal mask airway Reference Sinha PK, Misra S. Supraglottic airway devices other than LMA and its prototypes. Indian J anaesth. 2005;49(4):281–92. Hein C, Owen H, Plummer J. Randomized comparison of the SLIPA and the SS-LM by medical students. Emergency Medicine Australasia. 2006;18:478–83. Basket PJF, Brain AIJ, Handbook of the use of LMA in CPR. Intavent. 1998:1–14. Hein C. The Prehospital practitioner and the LMA: are you keeping Up?. J Emerg Primary Health Care. 2004:2; 1–2. Brimacombe JR, Berry AM, Daves SM, The LMA, Airway Management. Dalam: Hanowel LH, Penyunting Lippincott: Raven Publishers, Philadelphia;1996. Hlm.195–221. Rieger A, Brunne B, Striebel W. Use of manometry for laryngeal mask airway reduces postoperative pharyngolaryngeal adverse events, a prospective randomize trial. Anesthesiol. 2010; 112:652–7. Park PG, Choi GJ, Kim WJ, Yang SY, Shin HY, Kang H, dkk, A comparative study among normal saline, water soluble gel and 2% lidocaine gel as a SLIPA lubricant, Korean J Anesthesiol. 2014 February; 66(2): 105–111. Hein C. The prehospital practitioner and the laryngeal mask airway: “Are you keeping up?”. Austral Jo Paramed. 2004:2 (1) Vaida S. Airway management-Supraglotic Airway Devices. Timisoara. 2004. Strydom C, Le Roux. A clinical comparison of disposable airway devices. SAJAA. 2008; 14(6):31–36. Andre AZ. Comparison of the LMA-Classic with the new disposable soft seal laryngeal mask in spontaneously breathing adult patients. Anesthesiology. 2003;99:1066–71. Keijzer C, Buitelaar D. A Comparison of postoperative throat and neck complaints after the use of I-gel and the La Premiere Disposable laryngeal mask: a double-blinded, randomized, controlled trial. Anaesth Analg 2009; 109(4);1092–4. Cook TM, Gatward et al. A Cohort evaluation of the I-Gel airway in 100 elective patients. J Association Anaesthetists Great Britain Ireland 2008;63:1124–30. Roodneshin F, Agah M, Novel technique for placement of LMA in difficult pediatric airways. Tanaffos.2011;10(2):56–8. Mun’im A. Perbandingan dua macam teknik pemasangan sungkup laring pada penderita operasi elektif di RSUPN-CM tahun 1997. [Tesis]. Jakarta: Departemen Anestesiologi dan Terapi Intensif FKUI/RSCM. 1997. Payne FB, Wilkes NC. A prospective study of two insertion techniques of the laryngeal mask airway. Anesthesiol. 1996;85:3A. Malayanti. Keberhasilan pemasangan sungkup laring: perbandingan antara teknik baku dengan teknik putar 180o pada pasien operasi elektif. [Tesis]. Jakarta: Departemen Anestesiologi dan Terapi Intensif FKUI/ RSCM. 2002. Brimacombe J, Berry AM, Insertion of the LMA A Prospective Study of Four Techniques. Anaesth Intens Care. 1993;21:89–92 (4).
Waktu Pulih Pasien Pascavitrektomi: Perbandingan antara Rumatan Kombinasi Sevofluran 1,2 Vol% - Fentanil 1,2 Mcg/Kg/Jam dengan Rumatan Sevofluran 2 Vol% Marsaban, Arif HM.; Kapuangan, Christopher; Andria, Krisna
Majalah Anestesia dan Critical Care Vol 34 No 2 (2016): Juni
Publisher : Perdatin Pusat

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Waktu pulih yang cepat dan lancar telah menjadi kebutuhan yang penting bagi unit pembedahan, khususnya bagi unit yang &nbsp;memiliki beban jadwal operasi yang &nbsp;banyak. Kecepatan waktu pulih diperlukan untuk meningkatkan turn-over-rate unit tersebut. Efek sinergis kombinasi opioid dan gas anestesi telah digunakan secara umum untuk mempertahankan kedalaman anestesia intraoperatif. Hanya saja tidak terlalu banyak data mengenai waktu pulih kombinasi opioid dan gas inhalasi, khususnya kombinasi sevofluran-fentanil.&nbsp;&nbsp; Penelitian ini bertujuan untuk mengetahui perbedaan waktu pulih antara rumatan kombinasi sevofluran 1,2 vol% - fentanil 1,2 mcg/kg/jam dengan rumatan sevofluran 2 vol%. Penelitian ini merupakan uji klinis acak tersamar tunggal terhadap pasien yang menjalani operasi elektif vitrektomi di Rumah Sakit Cipto Mangunkusumo periode bulan Mei–Juli 2015 sebanyak 30 sampel subjek penelitian diambil dengan metode konsekutif. Waktu pulih pascaoperasi dicatat dan data waktu pulih dianalisis dengan uji independent sample t-test. Waktu pulih antara rumatan kombinasi sevofluran 1,2 vol%-fentanil 1,2 mcg/kg/jam dengan rumatan sevofluran 2 vol% memiliki perbedaan yang signifikan (p&lt;0,005 kombinasi rumatan sevofluran 1,2 vol%-fentanil 1,2 mcg/kg/jam memiliki waktu pulih (6,47±1,727 detik) yang lebih singkat dibanding dengan rumatan sevofluran 2 vol% (11,87±1,846 detik). Waktu pulih pascavitrektomi pada kelompok rumatan kombinasi sevofluran 1,2 vol%-fentanil 1,2 mcg/kg/jam lebih singkat secara bermakna dari pada waktu pulih pada kelompok rumatan sevofluran 2 vol%. Kata Kunci: Fentanil, paskavitrektomi, sevofluran, waktu pulih &nbsp; Postvitrectomy Recovery Time: The Comparison between Combination of Sevoflurane 1,2% - Fentanyl 1,2 mcg/kg/hour Maintenance and Sevofluran 2 vol% as Maintenance A fast and smooth anesthesia recovery time is desiredin &nbsp;surgical units, especially in units with tight operation schedules. Faster recovery time creates &nbsp;a high turn over rate. Opioid – volatile anesthetic combination has been used widely to maintain the depth of anesthesia because of their synergistic effect. But there was lack of data about recovery time of opioid-inhalation combination maintenance, particularly sevoflurane-fentanyl combination, whereas sevofluran and fentanyl has been used widely in anesthesia practice. The study aimed to compare the recovery time between combination of sevoflurane 1.2 vol% - fentanyl 1.2 mcg/kg/hour maintenance and sevoflurane 2 vol% maintenance. Methods. This was a single blind randomized study in patients underwentvitrectomy at Cipto Mangunkusumo hospital between May and July 2015. A total of 30 subjects were included in this study. The recovery time after surgery was recorded. Data was analyzed by independent sample t-test. There was a significant difference of recovery time between combination of sevoflurane 1.2 vol% - fentanyl 1.2 mcg/kg/hour as maintenance (6.47±1.727 seconds) and sevoflurane 2 vol% as maintenance (11.87±1.846 seconds) &nbsp;(p&lt;0.005. Postvitrectomy anesthesia recovery time was significantly faster in combination of sevoflurane 1,2 vol% - fentanyl 1,2 mcg/kg/hour maintenance group compared tosevoflurane 2 vol% maintenance group. Key words: Fentanyl, postvitrectomy, recovery time, sevoflurane
RETRACTED: Perubahan fungsi kognitif dan psikomotor residen anestesiologi dan terapi intensif setelah 32 jam kerja Muhammad Zulfadli Syahrul; Muhammad Ruswan Dachlan; Arif Hari Martono Marsaban; Diatri Nari Lastri
Majalah Kedokteran Andalas Vol 40, No 1 (2017): Published in May 2017
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22338/mka.v40.i1.p19-30.2017

Abstract

RETRACTEDFollowing a rigorous, carefully concerns and considered review of the article published in Majalah Kedokteran Andalas to article entitled "Perubahan fungsi kognitif dan psikomotor residen anestesiologi dan terapi intensif setelah 32 jam kerja" Vol 40, No 1, pp. 19-30, May 2017, DOI: http://dx.doi.org/10.22338/mka.v40.i1.p19-30.2017.This paper has been found to be in violation of the Majalah Kedokteran's Publication Ethics and has been retracted.The reason: Not all authors approve journal submission for publication based on the report from one of co-author.The document and its content has been removed from Majalah Kedokteran Andalas, and reasonable effort should be made to remove all references to this article.
Comparison between Intermittent Propofol Bolus Techniques and Target-Controlled Infusion in Patients Underwent Gastrointestinal Endoscopy Arif HM Marsaban; Luki Sumaratih; Pryambodho Pryambodho
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 3, December 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.499 KB) | DOI: 10.24871/1432013132-138

Abstract

Background: Nowadays, the use of propofol for sedation during gastrointestinal endoscopic procedure has become more popular, either by intermittent-bolus (IB) technique or target-controlled infusion (TCI). Theaim of this study was to compare the outcomes of both techniques including the total consumption of propofol, consumption per minute, total cost, side effects and its recovery time.Method: This study was a single-blinded randomized clinical trial conducted at Digestive Endoscopy Center, Cipto Mangunkusumo Hospital, Jakarta between October and November 2013. There were fifty patients with pre-operative American Society of Anesthesiologist (ASA) Physical Status Classification I-III, aged 18-65 years, body mass index 18-30 kg/m2 who were randomized to obtain sedation with IB propofol or TCI after having a premedication with 1 μg/kgBW fentanyl. The outcomes including the duration of sedation, total dose, propofol consumption per minute, the total cost, the incidence of hypotension, the incidence of desaturation, and recovery time were then evaluated using SPSS version 21.0.Results: Duration of procedure between two groups was not significantly different (p = 0.718). Total dose of propofol, its consumption per minute and total cost were higher in TCI group (p = 0.010; p = 0.004; p = 0.001). The incidence of hypotension, desaturation and recovery time were not  significantly different (p = 0.248; p = 0.609; p = 0.33) in both groups.Conclusion: IB technique is more efficient in terms of total propofol dose, consumption per minute and total cost compared to the TCI technique. The incidences of hypotension, desaturation and recovery time profiles were comparable between the two groups.Keywords: gastrointestinal endoscopy, intermittent bolus, propofol, sedation, TCI
Co-Authors Aldy Heriwardito Andi Ade Wijaya Andria, Krisna Arief Cahyadi Bona A. Fithrah Daryono, Maria Veronica Tita Ekaputri Hadi Firdaus, Riyadh Fransiska Kaligis Indah Pudjiningsih Irmia Kusumadewi Jefferson Hidayat Kapuangan, Christopher Lastri, Diatri Nari Luki Sumaratih Luki Sumaratih, Luki Martaria, Nency Muhammad Ruswan Dachlan Nainggolan, Gina Adriana Pryambodho Pryambodho Pryambodho Pryambodho, Pryambodho Rama Garditya, Rama Ratna F Soenarto Syahrul, Muhammad Zulfadli Yulian, Anggadria Iqbal Yundha, I G.N.A.D.