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All Journal ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) Conservative Dentistry Journal Odonto dental journal
Mandojo Rukmo
Department Of Conservative Dentistry, Faculty Of Dental MEdicene, Universitas Airlangga
Dentistry Health Professions Medicine & Pharmacology

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The effects of propylene glycol addition in the combination of calcium hydroxide and propolis on compressive and flexural strength Mandojo Rukmo; Nirawati Pribadi; Elisa Kusuma Wardani; Sukaton; Belinda Belinda Meilani Perdana Putri
Conservative Dentistry Journal Vol. 12 No. 1 (2022): January-June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cdj.v12i1.2022.32-37

Abstract

Background: The mechanical properties of pulp-capping materials may affect their resistance to fracture during placement of a final restorative material or while supporting an overlying restoration over time when the mastication process is carried out. The combination of calcium hydroxide and propolis as a pulp capping material has the weakness on mechanical properties so it is necessary to add another material to improve its mechanical properties. Propylene glycol is used as a vehicle because it improves its handling property. Purpose: To explain how the compressive and flexural strength of the pulp capping material in the combination of calcium hydroxide, propolis, and propylene glycol compared without adding of propylene glycol. Methods: The study used 4 treatment groups with each group consisting of 7 replications. Control group is a combination of calcium hydroxide-propolis with a ratio of 1: 1.5, group 1 is a combination of calcium hydroxide-propolis-propylene glycol 20% with a ratio of 1:1.5:0.375, group 2 is a combination of calcium hydroxide-propolis-propylene glycol 30% with a ratio of 1:1.5:0.375, and group 3 is a combination of calcium hydroxide-propolis-propylene glycol 30% with a ratio of 1:1.5:0.375. Materials were mixed according to comparison and printed on a cylindrical mold with the size of 4 mm x 6 mm and a block mold with the size 65 mmx10 mmx6 mm. Then, the compressive and flexural strength was tested using an Autograph test instrument. Results: The statistical analysis was performed with ANOVA and Tukey HSD’s post-hoc test. There were statistically significant differences on compressive and flexural strength between groups (P<0.05). Conclusion: Addition of propylene glycol in the combination of calcium hydroxide and propolis have an influence of increasing of compressive and flexural strength, especially in the addition of 40% propylene glycol.
STIMULASI EKSTRAK PROPOLIS PADA ODONTOBLAST LIKE CELLS YANG DIINDUKSI LACTOBACILLUS ACIDOPHILUS INAKTIF TERHADAP EKSPRESI TLR2 DAN TNFα Ira Widjiastuti; Nadia Irnatari; Mandojo Rukmo
Odonto : Dental Journal Vol 4, No 2 (2017): December 2017
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (446.899 KB) | DOI: 10.30659/odj.4.2.85-93

Abstract

Background: Lactobacillus acidophilus, Gram-positive bacterias that enterthe dentinal tissue during the carious process are suspected to influence the immune response in human dental pulp. Odontoblasts situated at the pulp dentin interface are the frst cells encountered by these bacteria and have an important role in this response. Lipoteichoic acid (LTA), a wall component of Gram-positive bacteria, triggered the activation of the odontoblasts. LTA upregulated the expression of its own receptor TLR2, as well as the production of proinflammatory cytokineTNFα. Propolis is a resinous material that holds a great potential as an antiinflammatory agent. Present studies have shown that propolis has a reduction effect towards the proinflammatory cytokines expression and favor pulp healing.Purpose: To reveal the moleculer mechanism of propolis stimulation onodontoblast like cells, induced by inactive Lactobacillus acidophilus.Methods: This review was presented in odontoblasts like cells culture induced by inactive Lactobacillus acidophilus and exposed to propolis extract. Pulp cell culture isolated from human impacted thirds molar that has been extracted. Observation and measurement the expression of TLR2 and TNFα was processed by using immunocytochemistry (ICC) technic.Result: Data analysis with ANOVA test, a signifcant difference in every group(p<0,05) was present. The expression of TLR2 and TNFα were shown at lowlevel percentation on odontoblast like cells, induced by Lactobacillus acidophilus and propolis extract stimulation.Conclusion: Propolis extract stimulations lower the TLR2 and TNFα expression on odontoblast like cells, induced by inactive Lactobacillus acidophilus
Co-Authors Adelina Kristanti Tandadjaja Afiono Agung Prasetyo Aprillia Sonya Federika Belinda Belinda Meilani Perdana Putri Deavita Dinari Devi Eka Juniarti Edhie Arief Prasetyo Edhie Arif Prasetyo Elisa Kusuma Wardani FX Ady Soesetijo, FX Ady Hendy Jaya Kurniawan Ira Widjiastuti Khilyat Ulin Nur Zaini Nadia Irnatari Nirawati Pribadi Qurni Restiani Randy Carlos Sietho Ratna Puspita Hadi Risya Cilmiaty Risya Cilmiaty Rosita Rahmawati Sepdhyo Wahyu Nugroho Setyabudi Setyabudi Suhartono Taat Putra Sukaton, Sukaton Tamara Yuanita Uli Sasi Andari Widya Asmara