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All Journal Universa Medicina GIZI INDONESIA Jurnal Penelitian dan Pengembangan Pelayanan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Kefarmasian Indonesia
Mihardja, Laurentia K.
National Institute Of Health Research And Develoment . Ministry Of Health Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Merokok dan usia sebagai faktor risiko katarak pada pekerja berusia ³ 30 tahun di bidang pertanian Tana, Lusianawaty; Mihardja, Laurentia; Rif’ati, Lutfah
Universa Medicina Vol 26, No 3 (2007)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2007.v26.120-128

Abstract

LATAR BELAKANGRuang lingkup penelitian ini adalah peranan faktor merokok dan katarak pada pekerja di bidang pertanian di Kabupaten Karawang. Katarak adalah kelainan mata berupa kekeruhan lensa, yang dapat mengganggu penglihatan bahkan sampai buta. 16% dari jumlah buta katarak di Indonesia terjadi di usia produktif. Salah satu tujuan penelitian adalah mendapatkan hubungan antara faktor merokok dengan katarak dalam rangka memperlambat katarak. METODERancangan adalah belah lintang. Sampel penelitian adalah petani dan keluarganya di Kecamatan Teluk Jambe Barat Kabupaten Karawang, dengan usia 30 tahun ke atas, yang terpilih secara purposive random sampling. Data diperoleh dengan wawancara, pemeriksaan dan pengukuran. Diagnosis katarak ditentukan oleh dokter spesialis mata dengan ophthalmoscope tanpa midriatika.Hasil Di samping faktor usia, faktor merokok mempunyai hubungan positif dengan katarak. Katarak berhubungan positip dengan merokok. Semakin berat derajat merokok maka semakin tinggi katarak.KesimpulanUsia dan merokok merupakan faktor risiko yang berhubungan positif dengan katarak pada pekerja di bidang pertanian.
KEBIASAAN MAKAN SAYUR DAN BUAH PADA PETANI YANG BERKAITAN DENGAN KEJADIAN KATARAK DI KECAMATAN TELUK JAMBE JAWA BARAT Mihardja, Laurentia; Tana, Lusianawaty; Ghani, Lannywati
GIZI INDONESIA Vol 31, No 2 (2008): September 2008
Publisher : PERSATUAN AHLI GIZI INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.271 KB)

Abstract

RISK OF CATARACT ASSOCIATED WITH FRUIT AND VEGETABLE INTAKE AMONG FARMERS OF WEST JAVARisk for cataract increases with age, but also has been associated with exposure to sunlight, andfactors such as smoking, and diet. We explored the risk of cataract in West Java, and found a strongassociation with diet, and a higher risk among malnourished adults. The aim of the study was to knowthe relationship between risk of c ataract and consumption of fruit and vegetables intake among farmersof West Java. This study using cross sectional design which was conducted among farmers and theirfamilies in West Teluk Jambe subdistrict, Karawang West Java, Indonesia. Randomly sampledindividual 30 years and older in the population and identified 1223 subjecs to participated in the study.Each subject was interviewed about vegetables and fruit consumption per day and per week previouslyand historical quantity of intake by use of questionnaire and food models. Anthropometry measurement(weight and height) were also undertaken. Ocular examinations were carried out by opthalmologist.The results showed that risk of cataract increases by age. The subjects for >55 years vs 30 – 54 yearsold give an odds ratio of 30.6.( 95% CI: 22.04- 42.5, p= 0.0001). Consumption of vegetables < 5serving vs = 5 serving perday had a significant odds ratio for cataract risks of 1.74 ( 95% CI: 1.04-2.91, p= 0.031). Intake of colourfull fruits had a similar odds ratio for < 1 serving vs = 1 serving per daywith an odds ratio for cataracts risks of 1.74 (95% CI: 1.26 – 2.4, p=0.001). Underweight (body massindex < 18.5) vs with > or = normal body weight was also very important with an odds ratio of 4 ( 95%CI: 3.2 – 5.8, p= 0.0001). Using binary logistic regression only ages, and nutritional status showed asignificant relationship with cataract risk. This study demonstrates that consumption of vegetables andfruits >5 serving per day, intake colourfull fruits >1 serving per day and having good nutrition withstatus BMI normal can reduce the risk for cataracs. To prevent cataracts it is important to promote theconsumption of vegetables and fruits, colourful fruit and to promote good nutritional status.Key words: cataract, fruit, vegetable, underweight
KEBIASAAN MAKAN SAYUR DAN BUAH PADA PETANI YANG BERKAITAN DENGAN KEJADIAN KATARAK DI KECAMATAN TELUK JAMBE JAWA BARAT Mihardja, Laurentia; Tana, Lusianawaty; Ghani, Lannywati
GIZI INDONESIA Vol 31, No 2 (2008): September 2008
Publisher : PERSATUAN AHLI GIZI INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36457/gizindo.v31i2.57

Abstract

RISK OF CATARACT ASSOCIATED WITH FRUIT AND VEGETABLE INTAKE AMONG FARMERS OF WEST JAVARisk for cataract increases with age, but also has been associated with exposure to sunlight, andfactors such as smoking, and diet. We explored the risk of cataract in West Java, and found a strongassociation with diet, and a higher risk among malnourished adults. The aim of the study was to knowthe relationship between risk of c ataract and consumption of fruit and vegetables intake among farmersof West Java. This study using cross sectional design which was conducted among farmers and theirfamilies in West Teluk Jambe subdistrict, Karawang West Java, Indonesia. Randomly sampledindividual 30 years and older in the population and identified 1223 subjecs to participated in the study.Each subject was interviewed about vegetables and fruit consumption per day and per week previouslyand historical quantity of intake by use of questionnaire and food models. Anthropometry measurement(weight and height) were also undertaken. Ocular examinations were carried out by opthalmologist.The results showed that risk of cataract increases by age. The subjects for 55 years vs 30 – 54 yearsold give an odds ratio of 30.6.( 95% CI: 22.04- 42.5, p= 0.0001). Consumption of vegetables 5serving vs = 5 serving perday had a significant odds ratio for cataract risks of 1.74 ( 95% CI: 1.04-2.91, p= 0.031). Intake of colourfull fruits had a similar odds ratio for 1 serving vs = 1 serving per daywith an odds ratio for cataracts risks of 1.74 (95% CI: 1.26 – 2.4, p=0.001). Underweight (body massindex 18.5) vs with or = normal body weight was also very important with an odds ratio of 4 ( 95%CI: 3.2 – 5.8, p= 0.0001). Using binary logistic regression only ages, and nutritional status showed asignificant relationship with cataract risk. This study demonstrates that consumption of vegetables andfruits 5 serving per day, intake colourfull fruits 1 serving per day and having good nutrition withstatus BMI normal can reduce the risk for cataracs. To prevent cataracts it is important to promote theconsumption of vegetables and fruits, colourful fruit and to promote good nutritional status.Key words: cataract, fruit, vegetable, underweight
Peran dan Sinergitas Puskesmas Campakamulya Cianjur dalam Upaya Mengatasi Stunting di Wilayah Kerja Nova Sri Hartati; Made Dewi Susilawati; Laurentia Mihardja
Jurnal Penelitian dan Pengembangan Pelayanan Kesehatan List Just Accepted Manuscript and Article In Press 2020
Publisher : Jurnal Penelitian dan Pengembangan Pelayanan Kesehatan (Journal of Research and Development in Health Services)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jpppk.v0i0.3712

Abstract

Abstrak Gizi stunting saat ini menjadi salah satu masalah yang masih dihadapi. Sejak pemerintah mengeluarkan kebijakan tentang percepatan penanggulangan stunting, penanganan masalah stunting masih sangat lambat. Puskesmas menjadi ujung tombak dalam penanganan stunting melalui intervensi spesifik. Tujuan penulisan artikel ini adalah untuk mengetahui bagaimana peran puskesmas dalam penanganan stunting. Metodologi penelitian ini menggunakan rancangan studi mix method dengan menggali informasi dari pihak puskesmas, tokoh masyarakat dan masyarakat sehingga didapatkan gambaran mendalam tentang peranan puskesmas dalam usaha mengatasi stunting di wilayah kerja Puskesmas Campakamulya, Kabupaten Cianjur. Hasil penelitian menunjukkan bahwa puskesmas Campakamulya dalam keterbatasan geografis, SDM, berupaya dalam menangani stunting, namun belum maksimal dikarenakan tidak ada pedoman juknis penatalaksanaan stunting yang dapat diterapkan di puskesmas. Sementara ini penanganan masih berdasarkan pengalaman penanggulangan gizi buruk. Dukungan dari aparat desa dan masyarakat sudah mulai terlihat dalam menurunkan kasus stunting. Puskesmas perlu membuat inovasi yang dapat mengubah perilaku masyarakat dalam pencegahan stunting dengan memperhatikan penanganan perbaikan nutrisi pada anak sejak 1000 hari pertama kehidupan (HPK). Kata kunci: puskesmas, penanganan stunting Abstract Stunting nutrition is currently one of the problems that are still being faced. Since the government issued a policy on accelerating stunting reduction, the handling of stunting problems has been very slow. Primary health center are at the forefront of stunting management through specific interventions. The purpose of writing this article is to find out how the role of primary health center in handling stunting. Methodology this research used mix method study design by extracting information from the health center, community leaders and the community so that an in-depth picture of the role of the community health center in the effort to overcome stunting in the working area of ​​the Campakamulya primary health center, Cianjur Regency was obtained. The results showed that the Campakamulya primary health center in terms of geographic limitations, human resources, tried to deal with stunting, but it was not optimal because there were no technical guidelines for stunting management that could be applied in the primary health center. Meanwhile, the treatment is based on experience in overcoming malnutrition. Support from village officials and the community has begun to appear in reducing stunting cases. Primary health center need to make innovations that can change people's behavior in preventing stunting by paying attention to the handling of improved nutrition in children since the first 1000 days of life. Key words: primary health center, handling stunting
Potensi Fraksi Etil Asetat Ekstrak Daun Gambir (Uncaria gambir Roxb.) sebagai Antihiperlipidemia Yunarto, Nanang; Elya, Berna; Konadi, Laurentia
Jurnal Kefarmasian Indonesia VOLUME 5, NOMOR 1, FEBRUARI 2015
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v5i1.2959

Abstract

Hyperlipidemia is the main risk factor for atherosclerosis and coronary heart disease. Ethyl acetate fraction of gambier leaves extract (Uncaria gambir Roxb.) contains catechin secondary metabolites which have potency to be used as antihyperlipidemic. This study aimed to examine the antihyperlipidemic effect of ethyl acetate fraction of gambier leaves extract in vivo. Thirty six males of Sprague Dawley strain, 2,5 months old, were randomly divided into six groups: normal group, negative group (distilled water), positive group (simvastatin 2 mg/200 g bw), dose I (5 mg/200 g bw fraction), II (10 mg/200 g bw fraction) and III (20 mg/200 g bw fraction) groups. Rats were induced with high cholesterol and saturated fat feeds for 28 days, except in the normal group. Furthermore, rats were given the treatment for 28 days. The results showed when compared than negative control, dose III reduced of total cholesterol, triglycerides, LDL levels and increased HDL level (p
Hubungan Indeks Massa Tubuh Pada Pasien Diabetes Melitus Tipe 2 Dengan Komplikasi Retinopati Diabetik Di Rumah Sakit Bintang Amin Andriawan, Kadek; Prasetia, Toni; Yuniastini, Yuniastini; Mihardja, Laurentia
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 9 (2025): Volume 12 Nomor 9
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i9.20363

Abstract

Retinopati diabetik (RD) adalah Penyakit penyerta mikrovaskular umumnya ditemukan di penderita diabetes tipe 2 (DMT2) dan menjadi faktor pemicu utama hilangnya kemampuan melihat yang sebenarnya bisa dihindari. Peningkatan kejadian RD di Indonesia berbanding lurus dengan meningkatnya prevalensi DMT2. Salah satu faktor risiko penting dalam terjadinya penyakit penyerta tersebut adalah indeks massa tubuh (BMI). Studi ini dirancang untuk menganalisis korelasi antara BMI dengan penyakit penyerta retinopati diabetik pada pasien DMT2 Pengumpulan data dalam studi ini menggunakan analisis statistik berbasis cross-sectional yang dilaksanakan di Rumah Sakit Bintang Amin. Sampel terdiri dari 106 pasien DMT2 dengan komplikasi RD yang diambil menggunakan teknik purposive sampling. Dianalisis dengan uji chi-square dan tingkat signifikansi 5%. Hasil studi menunjukkan bahwa pasien didominasi oleh usia >55 tahun (67,9%), laki-laki (54,7%), dan memiliki BMI normal (43,4%). Penyakit penyerta retinopati diabetik yang paling umum adalah tahap proliferatif (PDR) sebesar 52,8%. Ditemukan bahwa pasien kegemukan yang tidak sehat dan obesitas tingkat lanjut memiliki tingkat insiden PDR yang lebih tinggi daripada NPDR, yaitu 81,2% pada pasien kelebihan berat badan dan 66,7% pada pasien obesitas. Hasil tes statistik menunjukkan hubungan yang signifikan antara komplikasi BMI dan RD (p = 0,015). Studi ini menunjukkan bahwa peningkatan BMI berkontribusi pada tingkat keparahan retinopati diabetik pada pasien DMT2.
Co-Authors Andriawan, Kadek Berna Elya Lannywati Ghani Lusianawaty Tana Lutfah Rif’ati Made Dewi Susilawati Nanang Yunarto Nanang Yunarto Nova Sri Hartati Prasetia, Toni Yuniastini, Yuniastini